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    Skeletal muscle revascularization
    1.
    发明申请
    Skeletal muscle revascularization 审中-公开
    骨骼肌血运重建

    公开(公告)号：US20080114343A1

    公开(公告)日：2008-05-15

    申请号：US11598476

    申请日：2006-11-13

    申请人： James Lowe ,  Gary Allen ,  Elbert Tzeng ,  Richard Lanigan ,  John McIntyre

    发明人： James Lowe ,  Gary Allen ,  Elbert Tzeng ,  Richard Lanigan ,  John McIntyre

    IPC分类号： A61B18/18 ,  A61B17/34

    CPC分类号： A61B18/22 ,  A61B17/22012 ,  A61B17/3476 ,  A61B2017/00247 ,  A61B2017/3445 ,  A61B2017/3447 ,  A61B2018/00392 ,  A61B2018/2005

    摘要： Methods for the treatment of ischemic limbs. An energy source, which will typically be a laser energy source deployed through an optic fiber, is deployed subcutaneously to a site of ischemic skeletal muscle. At the site, a plurality of channels are preferably systematically formed with an appropriate amount of activated energy, which in turn can facilitate the restoration of blood flow through new blood vessel formation. Optionally, a needle or cannula can be deployed in conjunction with the energy source to help facilitate the formation of channel formation and/or deliver a therapeutic agent at the sight of channel formation. A sheath may also be utilized to house the optic fiber and deliver a therapeutic agent.

    摘要翻译： 治疗缺血性肢体的方法。 通常将通过光纤部署的激光能量源的能源皮下部署到缺血性骨骼肌的部位。 在该部位，多个通道优选地系统地形成有适量的活化能，这反过来可以促进通过新的血管形成恢复血流。 任选地，针或套管可以与能量源一起部署，以帮助促进通道形成的形成和/或在通道形成的视线下递送治疗剂。 也可以使用护套来容纳光纤并递送治疗剂。

    Tube occluder for occluding collapsible tubes
    3.
    发明申请
    Tube occluder for occluding collapsible tubes 有权
    用于封闭可收缩管的管封堵器

    公开(公告)号：US20050069425A1

    公开(公告)日：2005-03-31

    申请号：US10951441

    申请日：2004-09-28

    申请人： Larry Gray ,  Richard Lanigan

    发明人： Larry Gray ,  Richard Lanigan

    IPC分类号： A61M5/142 ,  A61M5/145 ,  A61M39/22 ,  F04B43/067 ,  F04B49/06 ,  F04B49/00 ,  F04B9/08

    CPC分类号： F04B45/06 ,  A61M1/1649 ,  A61M1/267 ,  A61M1/367 ,  A61M5/14 ,  A61M5/14224 ,  A61M5/14593 ,  A61M5/172 ,  A61M39/228 ,  A61M2205/12 ,  A61M2209/02 ,  F04B43/02 ,  F04B43/067 ,  F04B45/00 ,  F04B45/02 ,  F04B49/065 ,  F04B49/12 ,  F04B53/10 ,  F04B53/16 ,  G01M3/26 ,  G01M3/32 ,  G05D16/20

    摘要： The present invention involves, in some embodiments, mechanisms and methods of occluding collapsible tubing with an occluder to prevent fluid flow therethrough. In some embodiments, a tube occluding mechanism is disclosed that includes a bendable occluding member for creating a force that can be applied to a collapsible tube to occlude the tube. In some embodiments, the collapsible tube can be an inlet/outlet tube on a removable pumping cartridge that is coupled to a reusable pump drive component when the system is in operation. In such embodiments, the occluding mechanism can be attached to the reusable component and can be used to block fluid flow to and from the pumping cartridge. In some embodiments, the occluding member can comprises a spring plate which can create a force to occlude tubing when in a relaxed, unbent configuration, and which can be bent to unocclude the tubing. In some preferred embodiments, in a default configuration of the tube occluder mechanism (when no external force is applied to the occluding member) the tubes are occluded, so that the tube occluder mechanism provides a fail-safe configuration preventing fluid flow to and from a pumping cartridge to which the tubes can be connected.

    摘要翻译： 在一些实施例中，本发明涉及用闭塞器封闭可收缩管道以防止流体流过其中的机构和方法。 在一些实施例中，公开了一种管闭塞机构，其包括用于产生能够施加到可收缩管以封闭管的力的可弯曲闭塞构件。 在一些实施例中，可折叠管可以是可拆卸泵筒上的入口/出口管，其在系统运行时与可重复使用的泵驱动部件联接。 在这样的实施例中，闭塞机构可以附接到可重复使用的部件，并且可以用于阻止流入和流出泵送的流体。 在一些实施例中，闭塞构件可以包括弹簧板，弹簧板可以在处于松弛的，未弯曲的构造中时产生阻塞管道的力，并且可以弯曲以排除管道。 在一些优选实施例中，在管堵塞机构的默认配置（当外力不对阻塞构件施加时）管被封闭，使得管封堵器机构提供故障安全配置，防止流体流入和流出 泵可以连接到管道上。

    Vial loading method and apparatus for intelligent admixture and delivery of intravenous drugs
    4.
    发明授权
    Vial loading method and apparatus for intelligent admixture and delivery of intravenous drugs 失效
    用于智能混合和递送静脉注射药物的小瓶装载方法和装置

    公开(公告)号：US6070761A

    公开(公告)日：2000-06-06

    申请号：US916886

    申请日：1997-08-22

    申请人： Nicole D. Bloom ,  Dean L. Kamen ,  Richard Lanigan ,  Charles M. Grinnell ,  Kevin Grant

    发明人： Nicole D. Bloom ,  Dean L. Kamen ,  Richard Lanigan ,  Charles M. Grinnell ,  Kevin Grant

    IPC分类号： A61J3/00 ,  A61J7/00 ,  B65B3/00

    CPC分类号： A61J3/002 ,  G06F19/3468

    摘要： The present invention is directed toward a vial-loading mechanism for a system that prepares and delivers one or more IV drugs to a patient. The vial-loading mechanism is used to load a vial onto a cassette spike and includes a vertical support member located adjacent to the spike. A holding assembly holds at least one vial. The holding assembly is mounted to the support member so as to be positionable between an upper position for loading a vial and a lower position for piercing the vial with a spike. The holding assembly has an arcuate-shaped holding member for holding the vial. A catch is provided with an engagement unit for securing the holding assembly in the lower position. This arrangement provides an easy way to add, retain, and remove vials from the system and protects the clinicians that do this from contacting the spikes and hurting themselves.

    摘要翻译： 本发明涉及一种用于向患者制备和递送一种或多种IV药物的系统的小瓶装载机构。 小瓶加载机构用于将小瓶装载到盒钉上，并且包括邻近尖峰定位的垂直支撑构件。 保持组件容纳至少一个小瓶。 保持组件安装到支撑构件上，以便可以在用于装载小瓶的上部位置和用于用尖钉刺穿小瓶的下部位置之间定位。 保持组件具有用于保持小瓶的弓形保持构件。 卡扣具有用于将保持组件固定在较低位置的接合单元。 这种安排提供了一种简单的方法来添加，保留和从系统中移除小瓶，并保护临床医生不要接触尖峰并伤害自己。

    Disposable cassette, delivery set and system for peritoneal dialysis
    5.
    发明授权
    Disposable cassette, delivery set and system for peritoneal dialysis 失效
    一次性胶囊，输送装置和腹膜透析系统

    公开(公告)号：US5989423A

    公开(公告)日：1999-11-23

    申请号：US709864

    申请日：1996-09-10

    申请人： Dean Kamen ,  Richard Lanigan ,  Douglas E. Vincent

    发明人： Dean Kamen ,  Richard Lanigan ,  Douglas E. Vincent

    IPC分类号： A61M5/142 ,  A61M1/28 ,  F04B43/02

    CPC分类号： A61M1/28 ,  A61M1/281 ,  A61M2205/12

    摘要： A disposable cassette for use in peritoneal dialysis includes a pair of diaphragms, tube connectors, pump chambers, channel paths, and valves. A disposable dialysate delivery set for use in peritoneal dialysis includes a cassette, multiple liquid flow paths, multiple valves, tube connectors, and disposable flexible plastic tubes to convey dialysate to and from the patient and other locations within the system. A system for performing peritoneal dialysis includes disposable supply containers of fresh dialysate, a cassette including a pump, a disposable heater container, and conduits for carrying fresh dialysate and carrying heated dialysate.

    摘要翻译： 用于腹膜透析的一次性盒包括一对隔膜，管连接器，泵室，通道路径和阀。 用于腹膜透析的一次性透析液输送装置包括盒，多个液体流路，多个阀，管连接器和一次性柔性塑料管，以将透析液输送到患者和系统内的其他位置。 用于进行腹膜透析的系统包括新鲜透析液的一次性供应容器，包括泵，一次性加热器容器的盒，以及用于携带新鲜透析液并携带加热的透析液的导管。

    Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure
    9.
    发明授权
    Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure 失效
    使用流体压力的腹膜透析系统的液体泵送机制

    公开(公告)号：US5634896A

    公开(公告)日：1997-06-03

    申请号：US420196

    申请日：1995-04-11

    申请人： Robert J. Bryant ,  Clement D. Bouchard ,  Dean Kamen ,  Richard Lanigan ,  Bradley D. Miller ,  Geoffrey P. Spencer ,  Douglas E. Vincent

    发明人： Robert J. Bryant ,  Clement D. Bouchard ,  Dean Kamen ,  Richard Lanigan ,  Bradley D. Miller ,  Geoffrey P. Spencer ,  Douglas E. Vincent

    IPC分类号： A61M5/142 ,  A61M1/28 ,  A61M1/00 ,  A61M31/00

    CPC分类号： A61M1/28 ,  A61M1/281 ,  A61M1/288 ,  A61M2205/12 ,  Y10S128/12 ,  Y10S128/13

    摘要： Pumping mechanisms for performing peritoneal dialysis and the like employ a pumping mechanism comprising a diaphragm that operate in response to applied fluid pressure. Flexible tubing is attached to the pumping mechanism for carrying liquid to and from the patient's peritoneal cavity. An actuating station for pumping mechanism receives the pumping mechanism and attached tubing. A pressure transfer element conveys fluid pressure to the diaphragm for moving liquid through the cassette. An occluder element contacts and crimps closed the tubing attached to the cassette. A first reservoir inflates with positive fluid pressure for contacting the pressure transfer element to hold it in operative contact against the diaphragm. A second reservoir inflates with positive fluid pressure for contacting the occluding element to hold it away from crimping contact with the tubing. At least one of the first and second reservoirs also transports fluid pressure to the pressure transfer element for conveyance to the diaphragm.

    摘要翻译： 用于进行腹膜透析等的泵送机构采用泵送机构，其包括响应于所施加的流体压力而操作的隔膜。 柔性管连接到泵送机构，用于将液体输送到患者的腹膜腔和从患者的腹膜腔输送液体。 用于泵送机构的致动站接收泵送机构和连接的管道。 压力传递元件将流体压力传递到隔膜以使液体通过盒。 闭塞器元件接触并卷曲封闭连接到盒式磁带的管道。 第一储存器以正的流体压力膨胀以接触压力传递元件以使其与隔膜有效接触。 第二储存器以正的流体压力膨胀以接触封闭元件以将其远离与管道的压接接触。 第一和第二储存器中的至少一个还将流体压力传送到压力传递元件以传送到隔膜。

    Peritoneal dialysis systems and methods employing a liquid distribution and pump cassette with self-contained air isolation and removal
    10.
    发明授权
    Peritoneal dialysis systems and methods employing a liquid distribution and pump cassette with self-contained air isolation and removal 失效
    腹膜透析系统和采用液体分配的方法和具有独立空气隔离和去除的泵盒

    公开(公告)号：US5628908A

    公开(公告)日：1997-05-13

    申请号：US401352

    申请日：1995-03-09

    申请人： Dean Kamen ,  Richard Lanigan ,  Douglas E. Vincent

    发明人： Dean Kamen ,  Richard Lanigan ,  Douglas E. Vincent

    IPC分类号： A61M5/142 ,  A61M1/28

    CPC分类号： A61M1/28 ,  A61M1/281 ,  A61M2205/12

    摘要： Systems and methods for peritoneal dialysis establish flow communication between a patient's peritoneal cavity and a drain through a pump chamber having generally vertically spaced upper and lower regions andt a diaphragm. The systems and methods operate the pump chamber, with the upper and lower regions oriented generally vertically, by applying fluid pressure to the diaphragm. The systems and methods direct liquid to the patient's peritoneal cavity only from the lower region of the pump chamber. In this way, the improved systems and methods collect air in the upper region of the vertically oriented pump chamber, while isolating the patient's peritoneal cavity from air in the pump chamber.

    摘要翻译： 用于腹膜透析的系统和方法通过具有大致垂直间隔开的上部和下部区域的泵室以及隔膜来建立患者腹膜腔和排水管之间的流动连通。 系统和方法通过向隔膜施加流体压力来操作泵室，其中上部和下部区域大致垂直地取向。 系统和方法仅将液体从泵室的下部区域直接引导至患者的腹膜腔。 以这种方式，改进的系统和方法在垂直定向的泵室的上部区域中收集空气，同时将患者的腹膜腔与泵室中的空气隔离。