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    Bifurcation delivery systems and methods
    3.
    发明申请
    Bifurcation delivery systems and methods 失效
    分岔输送系统和方法

    公开(公告)号：US20080065141A1

    公开(公告)日：2008-03-13

    申请号：US11520920

    申请日：2006-09-13

    申请人： Tom Holman ,  Jan Weber

    发明人： Tom Holman ,  Jan Weber

    IPC分类号： A61M29/00 ,  A61F2/06

    CPC分类号： A61F2/954 ,  A61F2/856 ,  A61F2/958 ,  A61F2002/9583 ,  A61F2210/0033 ,  A61F2250/0074 ,  A61F2250/0097

    摘要： A catheter assembly including a side branch locator that is moveable between a retracted position within a main vessel of a vessel bifurcation, and an extended position wherein a distal end of the side branch locator extends into a branch vessel of the vessel bifurcation. The side branch locator includes a first end fixed relative to a portion of the catheter assembly that remains in the main vessel. A second end of the side branch locator is moveable between the retracted and extended positions. The catheter assembly can include a moveable sheath that holds the side branch locator in the retracted position. The catheter assembly can further include a stent having a lateral branch opening through which the side branch locator extends.

    摘要翻译： 一种导管组件，其包括可在容器分叉的主容器内的缩回位置之间移动的侧分支定位器和其中所述侧分支定位器的远端延伸到所述血管分叉的分支容器中的延伸位置。 侧分支定位器包括相对于保留在主容器中的导管组件的一部分固定的第一端。 侧分支定位器的第二端可在缩回位置和伸出位置之间移动。 导管组件可以包括将侧分支定位器保持在缩回位置的可移动护套。 导管组件还可以包括具有横向分支开口的支架，侧分支定位器通过所述横向分支开口延伸。

    Bifurcation delivery systems and methods
    4.
    发明授权
    Bifurcation delivery systems and methods 失效
    分岔输送系统和方法

    公开(公告)号：US08454681B2

    公开(公告)日：2013-06-04

    申请号：US11520920

    申请日：2006-09-13

    申请人： Tom Holman ,  Jan Weber

    发明人： Tom Holman ,  Jan Weber

    IPC分类号： A61F2/06

    CPC分类号： A61F2/954 ,  A61F2/856 ,  A61F2/958 ,  A61F2002/9583 ,  A61F2210/0033 ,  A61F2250/0074 ,  A61F2250/0097

    摘要： A catheter assembly including a side branch locator that is moveable between a retracted position within a main vessel of a vessel bifurcation, and an extended position wherein a distal end of the side branch locator extends into a branch vessel of the vessel bifurcation. The side branch locator includes a first end fixed relative to a portion of the catheter assembly that remains in the main vessel. A second end of the side branch locator is moveable between the retracted and extended positions. The catheter assembly can include a moveable sheath that holds the side branch locator in the retracted position. The catheter assembly can further include a stent having a lateral branch opening through which the side branch locator extends.

    摘要翻译： 一种导管组件，其包括可在容器分叉的主容器内的缩回位置之间移动的侧分支定位器和其中所述侧分支定位器的远端延伸到所述血管分叉的分支容器中的延伸位置。 侧分支定位器包括相对于保留在主容器中的导管组件的一部分固定的第一端。 侧分支定位器的第二端可在缩回位置和伸出位置之间移动。 导管组件可以包括将侧分支定位器保持在缩回位置的可移动护套。 导管组件还可以包括具有横向分支开口的支架，侧分支定位器通过所述横向分支开口延伸。

    Medical device having a coating layer with structural elements therein and method of making the same
    7.
    发明申请
    Medical device having a coating layer with structural elements therein and method of making the same 审中-公开
    具有其中具有结构元件的涂层的医疗装置及其制造方法

    公开(公告)号：US20060025848A1

    公开(公告)日：2006-02-02

    申请号：US10902747

    申请日：2004-07-29

    申请人： Jan Weber ,  Tom Holman

    发明人： Jan Weber ,  Tom Holman

    IPC分类号： A61F2/06

    CPC分类号： A61F2/82 ,  A61F2250/0067 ,  A61L31/08 ,  A61L31/127

    摘要： The invention pertains to coated medical devices, such as stents and balloon catheters, for delivering a biologically active material to body tissue of a patient. The medical device has a coating layer comprising a biocompatible polymer, non-polymer material, or biologically active material disposed on its surface, and at least one structural element embedded within the coating layer. The structural elements reduce the compressibility of the coating layer. The structural element may be any shape or configuration. A biologically active material may be dispersed within the coating layer or structural elements. Methods for making such medical devices are also disclosed.

    摘要翻译： 本发明涉及用于将生物活性物质递送到患者的身体组织的涂覆医疗装置，例如支架和球囊导管。 该医疗装置具有包含生物相容性聚合物，非聚合物材料或设置在其表面上的生物活性材料的涂层和至少一个嵌入该涂层内的结构元件。 结构元件降低了涂层的压缩性。 结构元件可以是任何形状或构造。 生物活性材料可以分散在涂层或结构元件内。 还公开了制造这种医疗装置的方法。

    Functional coatings and designs for medical implants
    8.
    发明申请
    Functional coatings and designs for medical implants 审中-公开
    功能性涂层和医疗植入物的设计

    公开(公告)号：US20050159805A1

    公开(公告)日：2005-07-21

    申请号：US10759605

    申请日：2004-01-20

    申请人： Jan Weber ,  Tom Holman ,  Tracee Eidenschink ,  John Chen

    发明人： Jan Weber ,  Tom Holman ,  Tracee Eidenschink ,  John Chen

    IPC分类号： A61F2/00 ,  A61F2/06 ,  A61F2/90 ,  A61L27/30 ,  A61L27/54 ,  A61L27/56 ,  A61L31/08 ,  A61L31/14 ,  A61L31/16

    CPC分类号： A61L31/16 ,  A61F2/91 ,  A61F2250/0068 ,  A61L31/082 ,  A61L31/146 ,  A61L2300/606

    摘要： The present invention regards an implant that may be uniquely shaped to enhance its functionality and that may also be coated with a coating system that affects its functionality. In one embodiment the implant may have a first surface that is covered with a filter material, the filter material being in contact with a catalyst that promotes the decomposition of Hydrogen Peroxide into Hydrogen and Oxygen. In this and other embodiments, this filter material may be made from ceramic materials and may be meso-porous. In another embodiment, the implant may or may not be coated with this system and may have at least one strut with a tapered cross-section, the cross-section becoming smaller in area when moving from a reference point on the inside of the implant to the outside of the implant.

    摘要翻译： 本发明涉及一种植入物，其可以是独特的形状以增强其功能，并且还可以涂覆有影响其功能的涂层系统。 在一个实施例中，植入物可以具有被过滤材料覆盖的第一表面，过滤材料与促进过氧化氢分解成氢气和氧气的催化剂接触。 在该实施例和其它实施例中，该过滤材料可以由陶瓷材料制成，并且可以是中孔多孔的。 在另一个实施例中，植入物可以涂覆或可以不涂覆该系统，并且可以具有至少一个具有锥形横截面的支柱，当从植入物内侧的参考点移动到该植入物的横截面时，横截面变小 外植入物。

    Applications of LIPSS in polymer medical devices
    9.
    发明授权
    Applications of LIPSS in polymer medical devices 有权
    LIPSS在聚合物医疗器械中的应用

    公开(公告)号：US08550985B2

    公开(公告)日：2013-10-08

    申请号：US11011454

    申请日：2004-12-14

    申请人： Jan Weber ,  Tom Holman

    发明人： Jan Weber ,  Tom Holman

    IPC分类号： A61B1/04 ,  A61B1/00 ,  A61M31/00 ,  A61M37/00

    CPC分类号： A61M25/0009 ,  A61M25/1027 ,  A61M2025/006 ,  A61M2025/0062 ,  A61M2025/09108 ,  A61M2025/09133 ,  A61M2025/1031

    摘要： Medical devices have material that that has a laser induced periodic surface structure (LIPSS) pattern on at least a portion thereof. The LIPSS pattern is provided by exposing a material surface to a pulsed polarized laser energy fluence below the ablation threshold. The LIPSS pattern is useful for purposes such as reducing contact areas on sliding surfaces, increasing total surface area for adhesions, providing anisotropic reinforcement of a material layer or layers, and to provide multiple channels for directing cell growth.

    摘要翻译： 医疗器械具有在其至少一部分上具有激光诱发的周期性表面结构（LIPSS）图案的材料。 通过将材料表面暴露于低于消融阈值的脉冲偏振激光能量通量来提供LIPSS图案。 LIPSS图案可用于减少滑动表面上的接触面积，增加用于粘连的总表面积，提供材料层或层的各向异性加强，以及提供用于引导细胞生长的多个通道。