公开(公告)号：US4411955A

公开(公告)日：1983-10-25

申请号：US316806

申请日：1981-11-02

申请人： Josef Mondt ,  Gerd Walz ,  Thaddaus Wirth

发明人： Josef Mondt ,  Gerd Walz ,  Thaddaus Wirth

IPC分类号： C08G59/00 ,  C08G59/14 ,  C08G59/24 ,  C08G59/34 ,  C08G59/42 ,  C08G59/48 ,  C08G59/68 ,  C08L33/00 ,  C08L33/02 ,  C08L63/00 ,  C08L67/00 ,  C09D163/00 ,  C09J163/00 ,  B32B27/28

CPC分类号： C08G59/027 ,  C08G59/145 ,  C08G59/24 ,  C08G59/42 ,  C08G59/4246 ,  C08G59/685 ,  C09D163/00 ,  Y10T428/31511

摘要： A reactive hardenable binder composition based on(A) at least one aliphatic, cycloaliphatic or aliphatic-cycloaliphatic polyepoxide wherein at least 2 epoxidized cycloaliphatic radicals are bound via an aliphatic bridge,(B) at least one polycarboxylic acid unit of formula ##STR1## having an acid number between 30 and 400 whereinR.sup.1 is a radical of an at least oligomer product selected from the group consisting of polyesters and polymers having initially free OH-groups,R.sup.2 is a radical of a dicarboxylic carbocyclic acid having a COOH-group in ortho-position to its ester bond and(C) a catalyst component of the formula ##STR2## wherein R.sup.3 is a radical of a homo- or copolymer or combination of both of an unsaturated carboxylic acid with a statistically distributed number of COOH side groups or the radical of a polyester having initially free COOH-groups andMe is one equivalent of an alkaline or an alkaline earth metal, thus being present in its salt form, a process for the preparation of hardened products from said composition and a coated article having a coating based on said composition.

摘要翻译： 一种基于（A）至少一种脂肪族，脂环族或脂族 - 脂环族聚环氧化物的反应性可硬化粘合剂组合物，其中至少2个环氧化脂环族基团通过脂族桥键合，（B）至少一种式（IMAGE）的多元羧酸单元 I），其酸值在30和400之间，其中R1是选自具有起始游离OH-基团的聚酯和聚合物的至少低聚物产物的基团，R 2是具有COOH- （C）催化剂组分，其中R 3是具有统计分布数的不饱和羧酸的均聚物或共聚物或两者的组合的基团 的COOH侧基或具有起始游离COOH基团的聚酯的基团，Me为1当量碱金属或碱土金属，因此以其盐形式存在，制备方法 所述组合物的硬化产物的定量和具有基于所述组合物的涂层的涂覆制品。

公开(公告)号：US4208488A

公开(公告)日：1980-06-17

申请号：US877868

申请日：1978-02-15

申请人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth

发明人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth

IPC分类号： C09D5/08 ,  C08G59/00 ,  C08G59/42 ,  C08L1/00 ,  C08L23/00 ,  C08L27/00 ,  C08L33/00 ,  C08L33/02 ,  C08L67/00 ,  C08L67/08 ,  C08L101/00 ,  C09D163/00 ,  C09D167/00 ,  C09J133/04 ,  C09J163/00 ,  C09J167/00 ,  C08L63/00

CPC分类号： C09D167/00 ,  C08K5/04 ,  C09J167/00

摘要： A thermosetting coating or adhesive composition based on (A) at least one component selected from the group consisting of oligomeric and polymeric compounds containing at least one of the functional groups hydroxyl and epoxy groups, and (B) a polycarboxylic acid mixture comprising trimellitic acid and a major amount of at least one compound of one of the formulae ##STR1## wherein R, R' and R'", being the same or different, each represents a di- to hexavalent hydrocarbon radical having a total of from 1 to 12 carbon atoms, said radical containing from zero to 2 olefinic double bonds, said radical without double bonds being interrupted by up to 3 ether bridges:x and y which may be the same or different, each represents an integer of from 2 to 6;t an integer of from 1 to 5; andz and u, which may be the same or different, each represents zero or an integer of from 1 to 5 and a process for coating a substrate with said composition.

摘要翻译： 一种基于（A）选自包含至少一个官能团羟基和环氧基团的低聚物和聚合物的至少一种成分的组合物的热固性涂料或粘合剂组合物，和（B）包含偏苯三酸和 主要量的至少一种下式之一的化合物：其中R，R'和R“'相同，其中R，R'和R”'相同 或不同的，每个表示总共具有1至12个碳原子的二价至六价烃基，所述基团含有0至2个烯属双键，所述无双键的基团被多达3个醚桥隔开：x和 y可以相同或不同，各自表示2〜6的整数; t为1〜5的整数; 和可以相同或不同的z和u各自表示0或1〜5的整数，以及用所述组合物涂布基材的方法。

公开(公告)号：US4465798A

公开(公告)日：1984-08-14

申请号：US357573

申请日：1982-03-12

申请人： Gerd Walz ,  Thaddaus Wirth ,  Walter Sprenger

发明人： Gerd Walz ,  Thaddaus Wirth ,  Walter Sprenger

IPC分类号： C08G59/00 ,  C08G59/14 ,  C08G59/34 ,  C08G59/42 ,  C09D163/00 ,  C08G59/04 ,  C08G59/08 ,  C08L63/04 ,  C08L63/10

CPC分类号： C08G59/027 ,  C08G59/4292 ,  C09D163/00 ,  Y10T428/31511 ,  Y10T428/31529

摘要： A water-dilutable epoxide which is free from glycidyl ester and glycidyl ether groups, characterized in that it contains, in addition to at least one epoxide group, at least one ester group of a monocarboxylic acid and a further ester group which is vicinally arranged thereto, this further ester group having been obtained by reaction of an OH group with a polycarboxylic monoanhydride, wherein the second COOH group formed from the anhydride by the esterification occurs wholly or partially in the form of a salt with a base; processes for preparing it and the use thereof in aqueous media or media compatible with water.

摘要翻译： 不含缩水甘油酯和缩水甘油醚基团的水可稀释的环氧化物，其特征在于，除了至少一个环氧基之外，它还包含至少一个单羧酸的酯基和其相邻的另外的酯基 该另外的酯基是通过OH基与多元羧酸单酐的反应获得的，其中通过酯化由酸酐形成的第二COOH基团全部或部分地与碱形成盐形成; 制备方法及其在与水相容的水性介质或介质中的用途。

公开(公告)号：US4542192A

公开(公告)日：1985-09-17

申请号：US382419

申请日：1982-05-26

申请人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth

发明人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth

IPC分类号： C08G59/00 ,  C08G59/42 ,  C08L33/00 ,  C08L33/02 ,  C08L63/00 ,  C08L67/00 ,  C09D163/00 ,  C08G85/00

CPC分类号： C08G59/4246

摘要： A reactive hardenable polymer mixture which comprises(A) at least one epoxy compound and(B) at least one polycarboxylic acid compound in the form of a component selected from the group consisting of(a) at least one compound of formula ##STR1## wherein R.sup.1 is a radical derived from at least one polymeric product containing hydroxy groups selected from the group consisting of a polymerization and a condensation product and a combination thereof in the form of polyesters, polymers each having a hydroxy number between 20 and 300, phenol resins having a hydroxy number between 100 and 800 and combinations thereof,R.sup.2 is a radical of an at least tetrabasic cyclic carboxylic acid having at least one COOH-group in an o- or peri-position to the ester bond,R.sup.5 is a radical of an at least dibasic cyclic carboxylic acid having at least one COOH-group in o- or peri-position to the ester bond and R.sup.5 may also be as defined for R.sup.2 ;(b) at least one at least tetrabasic cyclic carboxylic acid compound having 2 carboxylic groups in an o- or peri-position or at least one anhydride group or both together with at least one of the OH-group containing compounds from which the above defined group R.sup.1 is derived;(c) a least one compound corresponding to formula (I) or (Ia) as defined under (a) but with the proviso that the anhydride groups are replaced at least partially by a free acid or ester group or by both;(d) at least one compound as defined under (b) wherein the anhydride groups of the polycarboxylic acid compounds are replaced least partially by a free acid or ester group by both; and(e) any combination of (a) to (d), a process for the preparation of hardened products in hardening said composition.

摘要翻译： 一种反应性可硬化聚合物混合物，其包含（A）至少一种环氧化合物和（B）至少一种选自以下的组分形式的多元羧酸化合物：（a）至少一种式（IMAGE）化合物 （Ia）和其中R1是衍生自至少一种含聚合物的聚合物的基团，所述聚合物含有选自聚酯和聚合产物的聚合物的聚合物，其聚合物各自具有 羟基数在20和300之间，羟基数在100和800之间的酚树脂及其组合，R2是至少四元环状羧酸的基团，其具有至少一个COOH基， 酯键，R5是至少二元环状羧酸的基团，其在酯键的邻位置或至少一个位置具有至少一个COOH基团，R5也可以如R2所定义; （b）至少一种至少四元环状羧酸化合物，其在邻位或周期或至少一个酸酐基团中具有2个羧基，或者与至少一个含OH基化合物一起，上述定义的 组R1得出; （c）对应于（a）中定义的式（I）或（Ia）的至少一种化合物，但条件是至少部分地由游离酸或酯基或二者取代酸酐基团; （d）至少一种如（b）所定义的化合物，其中多羧酸化合物的酸酐基团被两者的最小部分地被游离酸或酯基取代; 和（e）（a）至（d）的任何组合，在硬化所述组合物时制备硬化产物的方法。

公开(公告)号：US4390688A

公开(公告)日：1983-06-28

申请号：US357571

申请日：1982-03-12

申请人： Gerd Walz ,  Thaddaus Wirth ,  Walter Sprenger

发明人： Gerd Walz ,  Thaddaus Wirth ,  Walter Sprenger

IPC分类号： C08G59/42 ,  C08G63/42 ,  C08G63/58 ,  C08G63/54 ,  C08L63/00

CPC分类号： C08G63/42 ,  C08G59/4284 ,  C08G63/58

摘要： A water dilutable polyester having a good resistance to hydrolysis based on(A) at least one dicarboxylic acid unit,(B) at least one polycarboxylic monoanhydride and(C) at least one alcohol component containing at least dihydric alcohol,the COOH groups of the polyester being at least partially present in the form of salts with amine, characterized in that the polyester is also derived from(D) at least one epoxy compound which contains at least two oxiran rings and is selected from the group consisting of epoxidized fatty acids, derivatives thereof and epoxidized aliphatic hydrocarbons or mixtures thereof with up to 30% of monoepoxides, the percentage being based on the epoxy groups, and in that the polycarboxylic monoanhydride (B) is incorporated in the form of a half ester and is other than phthalic anhydride and maleic anhydride.The invention also relates to a process for the preparation of such polyester, its use in a coating composition and to articles coated with such coating compositions.

摘要翻译： 基于（A）至少一种二羧酸单元，（B）至少一种聚羧酸单酐和（C）至少一种含至少二元醇的醇组分，具有良好的抗水解性的水可稀释聚酯， 聚酯至少部分以胺的形式存在，其特征在于聚酯还衍生自（D）至少一种含有至少两个环氧乙烷环的环氧化合物，并且选自环氧化脂肪酸， 其衍生物和环氧化脂族烃或其混合物与高达30％的单环氧化物，其百分比基于环氧基，并且多羧酸单酐（B）以半酯的形式引入，并且不同于邻苯二甲酸酐 和马来酸酐。 本发明还涉及制备这种聚酯的方法，其在涂料组合物中的用途以及用这种涂料组合物涂覆的制品。

公开(公告)号：US4240938A

公开(公告)日：1980-12-23

申请号：US021566

申请日：1979-03-16

申请人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth ,  Ernst-August Theiling

发明人： Kurt Kraft ,  Gerd Walz ,  Thaddaus Wirth ,  Ernst-August Theiling

IPC分类号： C08L67/00 ,  C08F20/26 ,  C08G59/00 ,  C08G59/14 ,  C08G59/18 ,  C08G59/42 ,  C08G63/12 ,  C08K5/09 ,  C08L63/00 ,  C08L67/08 ,  C09D163/00 ,  C09D167/00 ,  C09J163/00 ,  C09J167/00 ,  C08G85/00 ,  C09J3/12 ,  C09J3/14

CPC分类号： C08G59/4284 ,  C08G59/186 ,  C08G59/4246 ,  C09D167/00 ,  C09J167/00 ,  Y10T428/31515 ,  Y10T428/31786 ,  Y10T428/31794

摘要： A water-soluble reactive binder, characterized by a combination of at least three of the components(a) at least one halogen-free polycarboxylic acid compound;(b) at least one salt-forming substance selected from the group consisting of alkali metal, alkaline earth metal and quaternary ammonium salts, organic bases and ammonia;(c) at least one component selected from the group consisting of(c1) a polymer containing OH groups; and(c2) an epoxide compound,wherein the components (a) to (c2) are present as such or at least partially in chemically bonded form, a process for its preparation, an article coated with said binder and an adhesive containing said binder.

摘要翻译： 一种水溶性反应性粘合剂，其特征在于至少三种组分（a）至少一种无卤多元羧酸化合物的组合; （b）至少一种选自碱金属，碱土金属和季铵盐，有机碱和氨的成盐物质; （c）至少一种选自（c1）含OH基团的聚合物的组分; 和（c2）环氧化合物，其中组分（a）至（c2）本身或至少部分以化学键合形式存在，其制备方法，用所述粘合剂涂布的制品和含有所述粘合剂的粘合剂。

公开(公告)号：US20110229895A1

公开(公告)日：2011-09-22

申请号：US12160696

申请日：2007-01-17

申请人： Gerd Walz

发明人： Gerd Walz

IPC分类号： C12Q1/68 ,  C07K16/18 ,  G01N33/53

CPC分类号： G01N33/5091 ,  G01N33/6893 ,  G01N2800/347

摘要： The present invention relates to the diagnosis of renal disorders, in particular of polycystic kidney disease (PKD). The invention provides methods for diagnosing or monitoring the progression of PKD and test kits useful in those methods.

摘要翻译： 本发明涉及肾病，特别是多囊肾病（PKD）的诊断。 本发明提供用于诊断或监测PKD进展的方法和用于那些方法的测试试剂盒。

公开(公告)号：US5723583A

公开(公告)日：1998-03-03

申请号：US480036

申请日：1995-06-07

申请人： Brian Seed ,  Gerd Walz

发明人： Brian Seed ,  Gerd Walz

IPC分类号： A61K35/12 ,  A61K20060101 ,  A61K35/14 ,  A61K38/00 ,  A61K39/395 ,  A61P9/10 ,  A61P17/06 ,  A61P29/00 ,  A61P43/00 ,  C07K14/00 ,  C07K14/47 ,  C07K14/705 ,  C07K16/00 ,  C07K16/28 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N5/16 ,  C12N9/10 ,  C12N15/09 ,  C12N15/13 ,  C12N15/54 ,  C12P21/06 ,  C12P21/08 ,  G01N33/48 ,  G01N33/50 ,  G01N33/53 ,  G01N33/566 ,  G01N33/68

CPC分类号： C07K16/2854 ,  C07K14/4703 ,  C07K14/70564 ,  C07K14/70596 ,  C07K16/00 ,  A61K38/00 ,  C07K2317/41 ,  C07K2319/00 ,  Y10S435/972

摘要： Disclosed is a method of inhibiting the binding of a cell bearing a cell adhesion protein to a molecule or cell bearing a carbohydrate determinant specific for the cell adhesion molecule. The method involves contacting the cell adhesion protein-bearing cell with an inhibitor molecule bearing the carbohydrate determinant. Also disclosed is a method of inhibiting the binding of the first member of a specific binding pair to the second member of the specific binding pair, involving contacting the first member with an antibody which is specific for the first member and which is covalently bonded to a carbohydrate moiety which interferes with the antibody's ability to fix complement and bind an F.sub.c receptor. The methods of the invention may be used, for example, to reduce inflammation.

摘要翻译： 公开了抑制携带细胞粘附蛋白的细胞与具有细胞粘附分子特异性的碳水化合物决定簇的分子或细胞的结合的方法。 该方法包括使含细胞粘附蛋白的细胞与带有碳水化合物决定簇的抑制剂分子接触。 还公开了抑制特异性结合对的第一个成员与特异性结合对的第二个成员的结合的方法，包括使第一个成员与第一个成员具有特异性并且共价结合的抗体接触 碳水化合物部分干扰抗体固定补体并结合Fc受体的能力。 本发明的方法可以用于例如减少炎症。

公开(公告)号：US5466772A

公开(公告)日：1995-11-14

申请号：US205600

申请日：1994-03-03

申请人： Karl-Hans Angelmayer ,  Gerd Walz ,  Joachim Zoeller

发明人： Karl-Hans Angelmayer ,  Gerd Walz ,  Joachim Zoeller

IPC分类号： C08G18/67 ,  B01F17/52 ,  C08G18/08 ,  C08G18/28 ,  C08G18/32 ,  C08G18/34 ,  C08G18/48 ,  C08G18/66 ,  C08J3/03 ,  C08L67/00 ,  C08L67/02 ,  C08L75/16 ,  C09D175/14

CPC分类号： C08J3/03 ,  C08G18/0819 ,  C08G18/2825 ,  C08G18/283 ,  C08G18/284 ,  C08G18/2865 ,  C08G18/4833 ,  C08J2367/08 ,  Y10T428/31645 ,  Y10T428/31649

摘要： Unsaturated polyurethanes containing from 20 to 80% by weight of polyethylene glycol units, which can be prepared by reactinga) at least one organic polyisocyanate,b) an unsaturated fatty alcohol or its polyalkylene glycol ether, an unsaturated fatty amine or a reaction product of an unsaturated fatty acid and a monoepoxide,c) a compound which contains not only two groups which react with isocyanate groups but also at least one group which is ionic.d) a polyalkylene glycol having a molecular mass of from 750 to 10,000, and if desirede) a compound containing from three to six hydroxyl or amino groups,the ratio of the isocyanate groups in a) to the hydroxyl and amino groups in the remaining components being from 0.7:1 to 1.2:1. These unsaturated polyurethanes are used as dispersants for alkyd resins.

摘要翻译： 含有20至80重量％的聚乙二醇单元的不饱和聚氨酯可通过使a）至少一种有机多异氰酸酯，b）不饱和脂肪醇或其聚亚烷基二醇醚，不饱和脂肪胺或不饱和脂肪胺或 不饱和脂肪酸和单环氧化物，c）不仅含有与异氰酸酯基反应的两个基团，而且还含有至少一个离子性基团的化合物。 d）分子量为750至10,000的聚亚烷基二醇，如果需要，e）含有3-6个羟基或氨基的化合物，a）中的异氰酸酯基与剩余的羟基和氨基的比例 组分为0.7:1至1.2:1。 这些不饱和聚氨酯用作醇酸树脂的分散剂。

公开(公告)号：US4704442A

公开(公告)日：1987-11-03

申请号：US826789

申请日：1986-02-06

申请人： Christoph Just ,  Dieter Plath ,  Gerd Walz

发明人： Christoph Just ,  Dieter Plath ,  Gerd Walz

IPC分类号： C08F222/22 ,  C09D135/00 ,  C08F24/00

CPC分类号： C08F222/22 ,  C09D135/00

摘要： Copolymers based on (A) 5-95% by weight of at least one polymerizable carbamoyloxyalkyldicarboxylic acid ester, carrying hydroxyl groups, of the general formula I ##STR1## in which R.sup.1 represents hydrogen or alkyl or hydroxyalkyl having in each case 1 to 30 carbon atoms in the alkyl radical, R.sup.2 represents alkyl or hydroxyalkyl having in each case 1 to 30 carbon atoms in the alkyl radical, or the radical ##STR2## subject to the proviso that R.sup.1 is hydrogen and x is an integer from 2 to 10, R.sup.3 represents linear or branched alkylene having 2 to 5 carbon atoms, R.sup.4 represents hydrogen or methyl and R.sup.5 represents hydroxyalkyl or hydroxyaminoalkyl having in each case 2 to 20 carbon atoms in the alkyl radical, or an alkyl radical of this type which also contains ester groups and/or ether groups, and (B) 5-95% by weight of at least one copolymerizable monomer belonging to the group comprising (a) .alpha.,.beta.-olefinically unsaturated monocarboxylic acid and alkyl and hydroxyalkyl esters thereof having in each case 1 to 18 carbon atoms in the alkyl radical, and amides and nitriles thereof, and also monoalkyl and dialkyl esters of .alpha.,.beta.-olefinically unsaturated dicarboxylic acids having 1 to 18 carbon atoms in the alkyl radical, (b) vinyl-aromatic monomers, (c) vinyl esters of organic monocarboxylic acids having 1 to 18 carbon atoms in the carboxylic acid radical, and (d) glycidyl esters of unsaturated monocarboxylic and/or dicarboxylic acids, the sum of the components (A) and (B) being in all cases 100% by weight, and a process for their preparation.The copolymers are used for the preparation of shaped articles and/or coatings which have excellent properties.

摘要翻译： 基于（A）5-95重量％的至少一种带有羟基的可聚合的氨基甲酰氧基烷基二羧酸酯，其通式为Ⅰ，其中R1代表氢或烷基或羟基烷基，其中在每种情况下为1-30碳 烷基中的原子，R 2表示在每个情况下在烷基中具有1至30个碳原子的烷基或羟烷基，或者基团，条件是R 1是氢且x是2至10的整数，R 3 表示具有2至5个碳原子的直链或支链亚烷基，R4表示氢或甲基，R5表示在烷基中各自为2至20个碳原子的羟基烷基或羟基氨基烷基，或还含有酯基的这种类型的烷基， /或醚基，和（B）5-95重量％的至少一种可共聚单体，其属于包含（a）α，β-烯属不饱和一元羧酸及其烷基和羟烷基酯的组 在每种情况下，烷基中的1至18个碳原子，以及其酰胺和腈，以及在烷基中具有1至18个碳原子的α，β-烯属不饱和二羧酸的单烷基和二烷基酯，（b）乙烯基 - 芳族单体，（c）在羧酸基团中具有1至18个碳原子的有机单羧酸的乙烯基酯，和（d）不饱和一元羧酸和/或二羧酸的缩水甘油酯，组分（A）和（ B）在所有情况下为100重量％，以及其制备方法。 共聚物用于制备具有优异性能的成型制品和/或涂层。