Separation structure
    3.
    发明授权

    公开(公告)号:US07833478B2

    公开(公告)日:2010-11-16

    申请号:US11871614

    申请日:2007-10-12

    IPC分类号: G01N9/30 G01N33/00 F16K17/36

    摘要: A centrifugal-based microfluidic device (1) that comprises a hydrophilic microchannel structure (2) in which there is a A) a separation microcavity I (4) that comprises i) a liquid inlet I (5), and ii) a liquid outlet I (6) that is at a level below the level of liquid inlet I (5) and above the level of the bottom (8) of the microcavity (4) thereby defining a lower part (4b) and an upper part (4a) of the microcavity (4), and B) a microconduit I (17) that has an inlet end I (16) directly connected to liquid outlet I (6), and an outlet end I (18) that is at a lower level than inlet end I (6). A capillary valve I (24) is associated with microconduit I (17). The flow direction through liquid outlet I (6) is directed upwards and/or liquid outlet I (6) is placed in a downwardly turned part of an inner wall of the separation microcavity (4), and/or the part of microconduit I (17) next to liquid outlet I (6) is directed upwards.

    SEPARATION STRUCTURE
    4.
    发明申请
    SEPARATION STRUCTURE 审中-公开
    分离结构

    公开(公告)号:US20080206110A1

    公开(公告)日:2008-08-28

    申请号:US11871614

    申请日:2007-10-12

    IPC分类号: B01L11/00

    摘要: A centrifugal-based microfluidic device (1) that comprises a hydrophilic microchannel structure (2) in which there is a A) a separation microcavity I (4) that comprises i) a liquid inlet I (5), and ii) a liquid outlet I (6) that is at a level below the level of liquid inlet I (5) and above the level of the bottom (8) of the microcavity (4) thereby defining a lower part (4b) and an upper part (4a) of the microcavity (4), and B) a microconduit I (17) that has an inlet end I (16) directly connected to liquid outlet I (6), and an outlet end I (18) that is at a lower level than inlet end I (6). A capillary valve I (24) is associated with microconduit I (17). The flow direction through liquid outlet I (6) is directed upwards and/or liquid outlet I (6) is placed in a downwardly turned part of an inner wall of the separation microcavity (4), and/or the part of microconduit I (17) next to liquid outlet I (6) is directed upwards.

    摘要翻译: 一种离心式微流体装置(1),其包括亲水性微通道结构(2),其中存在A)分离微腔I(4),其包括i)液体入口I(5),和ii)液体出口 I(6)处于低于液体入口I(5)的水平并且高于微腔(4)的底部(8)的水平的水平面,由此限定下部(4b)和上部(4) a)的微腔(4),以及B)具有直接连接到液体出口I(6)的入口端I(16)的微型管I(17)和位于下部的出口端I(18) 水平高于入口端I(6)。 毛细管阀I(24)与微管I(17)相关联。 通过液体出口I(6)的流动方向被向上引导和/或液体出口I(6)放置在分离微腔(4)的内壁的向下转动的部分中,和/或微管I 液体出口I(6)旁边的图17所示向上。

    Structural units that define fluidic functions
    10.
    发明授权
    Structural units that define fluidic functions 失效
    定义流体功能的结构单元

    公开(公告)号:US07429354B2

    公开(公告)日:2008-09-30

    申请号:US10472255

    申请日:2002-03-19

    IPC分类号: G01N21/00

    摘要: A microfluidic device that comprises several microchannel structures in which there are an inlet port, an outlet port and therebetween a substructure comprising a fluidic function. The device has an axis of symmetry around which the microchannel structures are arranged as two or more concentric annular zones. for an inlet port and an outlet port of the same microchannel structure the inlet port is typically closer to the axis of symmetry than the outlet port. Each microchannel structure comprises a substructure that can retain liquid while the disc is spun around the axis and/or the inlet ports are positioned separate from the paths waste liquid leaving open waste outlet ports will follow across the surface of the disc when it is spun. For the microchannel structures of an annular zones the corresponding substructures are at essentially at the same radial distance while corresponding substructures in microchannel structures of different annular zones are at different radial distances. The invention also refers to several other substructures. The substructure are primarily adapted for transporting liquid aliquots that have a surface tnsion >5 mN/m with centrifugal force.

    摘要翻译: 一种微流体装置,其包括几个微通道结构,其中存在入口端口,出口以及其间具有流体功能的子结构。 该装置具有对称轴,微通道结构围绕该轴布置为两个或更多个同心的环形区域。 对于相同微通道结构的入口和出口,入口通常比出口更接近对称轴。 每个微通道结构包括一个子结构,其可以在圆盘围绕轴线旋转时保持液体,和/或入口端口与路径分离,离开开放废料出口的废液在旋转时将跟随盘的表面。 对于环形区域的微通道结构,相应的子结构基本上处于相同的径向距离,而不同环形区域的微通道结构中的相应子结构处于不同的径向距离。 本发明还涉及几个其他子结构。 子结构主要适用于输送具有离心力的表面尺寸> 5mN / m的液体等分试样。