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公开(公告)号：US09445809B2
公开(公告)日：2016-09-20
申请号：US13901888
申请日：2013-05-24
Applicant: Searete LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y.H. Wood
IPC: A61B17/068 , A61B17/072 , A61B17/115 , A61B17/00 , A61B17/29
CPC classification number: A61B17/068 , A61B17/00491 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/00022 , A61B2017/00221 , A61B2017/00398 , A61B2017/00402 , A61B2017/00871 , A61B2017/07214 , A61B2017/07278 , A61B2017/2905
Abstract: Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.
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公开(公告)号：US09020592B2
公开(公告)日：2015-04-28
申请号：US14101022
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with electrical blocking stimuli are disclosed. In an aspect, neural activity is blocked cyclically with an electrical blocking stimulus source implanted adjacent a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过具有电阻塞刺激的周围神经结构中的传导的循环阻断来调节神经活动的方法和相关系统。 在一个方面，神经活动被循环地阻挡，其中植入邻近神经的电阻塞刺激源。 在一方面，在感觉神经中产生传导阻滞。 神经调节可用于例如调节免疫或炎症反应或过程。
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公开(公告)号：US09014802B2
公开(公告)日：2015-04-21
申请号：US14100982
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61N1/18 , A61N7/00 , A61B5/11 , A61B5/00 , A61M5/142 , A61M5/172 , A61M35/00 , A61N1/04 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/145 , A61F7/00 , A61M5/168 , A61M37/00 , A61N1/30 , A61N1/32 , A61N1/36 , A61N1/372 , A61N2/00
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclically blocking conduction in peripheral neural structures are disclosed. In an aspect, neural activity is blocked cyclically with a blocking stimulus source positioned adjacent a skin surface in a vicinity of a nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过循环阻断外周神经结构传导来调节神经活动的方法和相关系统。 在一个方面，神经活动被周期性阻断，其中阻塞刺激源位于邻近神经附近的皮肤表面。 神经调节可用于例如调节免疫或炎症反应或过程。
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公开(公告)号：US09358374B2
公开(公告)日：2016-06-07
申请号：US14683198
申请日：2015-04-10
Applicant: Searete LLC
Inventor： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61N1/18 , A61M35/00 , A61B5/11 , A61B5/00 , A61M5/142 , A61M5/172 , A61N1/04 , A61N7/00 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/145 , A61F7/00 , A61M5/168 , A61M37/00 , A61N1/30 , A61N1/32 , A61N1/36 , A61N1/372 , A61N2/00
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures are disclosed. Neural activity may blocked cyclically by blocking stimuli delivered via various types of blocking stimulus sources. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an undesired sensation, such as pain, or an immune or inflammatory response or process. Delivery of blocking stimuli may be controlled in part in response to an input from a user input device.
Abstract translation: 公开了通过循环阻断外周神经结构传导来调节神经活动的方法和相关系统。 通过阻断通过各种类型的阻断刺激源递送的刺激，神经活动可能会周期性阻断。 在一方面，在感觉神经中产生传导阻滞。 例如，可以使用神经调节来调节不期望的感觉，例如疼痛，或免疫或炎症反应或过程。 可以部分地响应于来自用户输入设备的输入来控制传递阻塞刺激。
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5.发明授权Systems, devices, and methods including infection-fighting and monitoring shunts 有权系统，设备和方法，包括感染和监控分流公开(公告)号：US09149648B2
公开(公告)日：2015-10-06
申请号：US13715296
申请日：2012-12-14
Applicant: Searete LLC
Inventor： Ralph G. Dacey, Jr. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC: A61B19/00 , A61N5/06 , A61L2/00 , A61L2/08 , A61L2/14 , A61N1/20 , A61M27/00 , A61B5/00 , A61B5/145 , A61M5/142 , A61N1/372 , A61N1/378 , A61N1/40 , A61N5/02 , A61N5/10 , A61N7/00 , A61B5/053 , A61B5/1459 , A61B5/1473 , A61B18/20
CPC classification number: A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
Abstract: Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
Abstract translation: 描述了用于提供被配置为例如监视，治疗或预防感染的主动控制分路的系统，装置，方法和组合物。
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Patent Agency Ranking
公开(公告)号：US08815163B2
公开(公告)日：2014-08-26
申请号：US13950849
申请日：2013-07-25
Applicant: Searete LLC
Inventor： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Jordin T. Kare , Erez Lieberman Aiden , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
IPC: G05B9/00
CPC classification number: G01N31/223 , D03D15/00 , D10B2401/20 , G08B21/245 , Y10T428/239
Abstract: A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling layer is configured to release a gas-phase chemical compound to signal to a detector indicating a breach of the multilayer material. A multilayer material, a system, an article of clothing, or a method is described herein.
Abstract translation: 本文描述了一种多层材料，其包括柔性内层和柔性外层，其被配置为包围至少一个信号层，所述至少一个信号层包括至少一种化学化合物。 包括至少一个信号层内的化合物的多层材料被配置为释放气相化合物以向检测器发出信号，指示破坏多层材料。 本文描述了多层材料，系统，服装或方法。
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公开(公告)号：US20140163432A1
公开(公告)日：2014-06-12
申请号：US14100998
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, JR. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, JR. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61N7/00
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with ultrasound are disclosed. In an aspect, neural activity is blocked cyclically with an ultrasonic blocking stimulus source positioned adjacent a skin surface in a vicinity of a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过用超声周期性阻断外周神经结构传导来调节神经活动的方法和相关系统。 在一个方面，神经活动被周期性阻挡，超声阻断刺激源位于神经附近的皮肤表面附近。 在一方面，在感觉神经中产生传导阻滞。 神经调节可用于例如调节免疫或炎症反应或过程。
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公开(公告)号：US20130309137A1
公开(公告)日：2013-11-21
申请号：US13950849
申请日：2013-07-25
Applicant: Searete LLC
Inventor： Mahalaxmi Gita Bangera , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Jordin T. Kare , Erez Lieberman Aiden , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Lowell L. Wood
IPC: G01N31/22
CPC classification number: G01N31/223 , D03D15/00 , D10B2401/20 , G08B21/245 , Y10T428/239
Abstract: A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling layer is configured to release a gas-phase chemical compound to signal to a detector indicating a breach of the multilayer material. A multilayer material, a system, an article of clothing, or a method is described herein.
Abstract translation: 本文描述了一种多层材料，其包括柔性内层和柔性外层，其被配置为包围至少一个信号层，所述至少一个信号层包括至少一种化学化合物。 包括至少一个信号层内的化合物的多层材料被配置为释放气相化合物以向检测器发出信号，指示破坏多层材料。 本文描述了多层材料，系统，服装或方法。
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公开(公告)号：US09563934B2
公开(公告)日：2017-02-07
申请号：US14788455
申请日：2015-06-30
Applicant: SEARETE LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Thomas A. Weaver , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC classification number: G06T3/0075 , G06K2209/05 , G06T3/0006 , G06T7/0012 , G06T7/33 , G06T2200/04 , G06T2207/10072 , G06T2207/30016 , G06T2207/30048 , G06T2207/30061 , G06T2207/30101
Abstract: A method may include processing two or more fiducials included in a three-dimensional medical image and included in a current image to generate two or more transform coefficients of a transform, and applying the transform to the three-dimensional medical image to form a present image.
Abstract translation: 一种方法可以包括处理包括在三维医学图像中并包括在当前图像中的两个或更多个基准以产生变换的两个或更多个变换系数，并将变换应用于三维医学图像以形成当前图像 。
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公开(公告)号：US20140163483A1
公开(公告)日：2014-06-12
申请号：US14100982
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, JR. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, JR. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61M35/00
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclically blocking conduction in peripheral neural structures are disclosed. In an aspect, neural activity is blocked cyclically with a blocking stimulus source positioned adjacent a skin surface in a vicinity of a nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过循环阻断外周神经结构传导来调节神经活动的方法和相关系统。 在一个方面，神经活动被周期性阻断，其中阻塞刺激源位于邻近神经附近的皮肤表面。 神经调节可用于例如调节免疫或炎症反应或过程。
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