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    Systems configured to transmit optical power signals transdermally out of a living subject, and devices and methods
    5.
    发明授权
    Systems configured to transmit optical power signals transdermally out of a living subject, and devices and methods 有权
    被配置为透过光学功率信号从活体传送的系统，以及设备和方法

    公开(公告)号：US09166411B2

    公开(公告)日：2015-10-20

    申请号：US13710138

    申请日：2012-12-10

    Applicant: SEARETE LLC

    Inventor： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Dennis J. Rivet ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

    IPC: A61N1/378 ,  H02J4/00 ,  A61N1/372 ,  H02J17/00 ,  H04B10/114 ,  H04B13/00

    CPC classification number: H02J4/00 ,  A61N1/37217 ,  A61N1/37223 ,  A61N1/3785 ,  H02J17/00 ,  H02J50/30 ,  H02J50/40 ,  H02J50/90 ,  H04B10/1141 ,  H04B13/005

    Abstract: In an embodiment, a system includes an internal optical power transmitter configured to be disposed within a living subject. The internal optical power transmitter includes a power source configured to provide electrical energy and an electrical-optical converter operably coupled to the power source. The electrical-optical converter may be configured to convert at least a portion of the electrical energy into one or more optical power signals transdermally transmittable out of the living subject. The system further includes an external optical-electrical converter configured to convert the one or more optical power signals into one or more electrical power signals and at least one external device configured to be operably coupled to the external optical-electrical converter and powered by the one or more electrical power signals. Embodiments of methods, biocompatible electrical-optical converters, and internal optical power transmitters are also disclosed.

    Abstract translation: 在一个实施例中，系统包括被配置为设置在活体内的内部光功率发射器。 内部光功率发射器包括被配置为提供电能的电源和可操作地耦合到电源的电 - 光转换器。 电 - 光转换器可以被配置为将至少一部分电能转换成从活体中经皮透过的一个或多个光功率信号。 该系统还包括外部光电转换器，其被配置为将一个或多个光功率信号转换成一个或多个电功率信号，以及至少一个外部设备，被配置为可操作地耦合到外部光电转换器并由一个 或更多的电功率信号。 还公开了方法，生物相容性电光转换器和内部光功率发射器的实施例。

    Device for passively removing a target component from blood or lymph of a vertebrate subject
    7.
    发明授权
    Device for passively removing a target component from blood or lymph of a vertebrate subject 有权
    用于从脊椎动物受试者的血液或淋巴中被动成分去除目标成分的装置

    公开(公告)号：US09061094B2

    公开(公告)日：2015-06-23

    申请号：US13656964

    申请日：2012-10-22

    Applicant: Searete LLC

    Inventor： Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Robert Langer ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Elizabeth A. Sweeney ,  Lowell L. Wood, Jr.

    IPC: A61M37/00 ,  A61M1/00 ,  A61F2/82 ,  A61M1/36 ,  A61B5/145 ,  A61M5/00 ,  A61B18/18 ,  A61M5/142 ,  A61N5/02 ,  A61N5/06 ,  A61N7/00

    CPC classification number: A61B5/14503 ,  A61B18/18 ,  A61F2/82 ,  A61M1/00 ,  A61M1/362 ,  A61M1/3679 ,  A61M1/3681 ,  A61M1/3683 ,  A61M5/00 ,  A61M5/007 ,  A61M5/14276 ,  A61M2202/0405 ,  A61M2205/04 ,  A61N5/02 ,  A61N5/0601 ,  A61N5/062 ,  A61N7/00

    Abstract: Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components.

    Abstract translation: 本文描述了用于控制或调节脊椎动物受试者的血液和/或淋巴中的一种或多种靶组分的水平的装置，系统和方法。 提供了设备和系统，其包括限定被配置用于流体流动的至少一个内腔的主体; 流体流入所述至少一个内腔中的至少一个可控流动屏障; 设置在体内并被配置为包括一个或多个双功能标签的至少一个第一储存器，其中所述一个或多个双功能标签被配置为选择性地结合脊椎动物的一种或多种血液流体或淋巴液中的一种或多种靶组分 学科; 设置在所述至少一个内腔内的至少一个治疗区域; 以及设置在所述至少一个处理区域中并且被配置为包括一个或多个反应性组分的至少一个第二储存器，其中所述一个或多个反应性组分被配置为当结合到所述一种或多种靶组分时螯合所述一种或多种双功能标签 。

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