摘要:
The present invention provides immunomodulatory compositions include an immune response modifier moiety coupled to a targeting moiety. In another aspect, the invention provides methods of providing targeted delivery of an IRM, generating a localized immune response, and treating a condition in a subject. Generally, the methods include administering to the subject an immunomodulatory composition that includes an immune response modifier moiety coupled to a targeting moiety that recognizes a delivery target.
摘要:
Fluoropolymeric substrates are modified by a photochemical process that includes at least one species having the formula wherein: R represents hydrogen or an alkyl or cycloalkyl group having from 1 to 18 carbon atoms or an aryl, alkaryl, or aralkyl group having from 6 to 18 carbon atoms; X represents O or NH; and each of R1, R2, R3, and R4 independently represents H, an alkyl group having from 1 to 18 carbon atoms, an alkenyl group having from 1 to 18 carbon atoms, an aryl group having from 6 to 10 carbon atoms, or any two of R, R1, R2, R3, and R4 taken together represent an alkylene group having from 2 to 6 carbon atoms, with the proviso that at least one of R1 and R2 or at least one of R3 and R4 is not H.
摘要:
An economic, optically transmissive, stain and ink repellent, durable low refractive index fluoropolymer composition for use in an antireflection film or coupled to an optical display. In one aspect of the invention, the composition is formed from the reaction product of a fluoropolymer and a fluoroalkyl containing multi-olefinic crosslinker. In another aspect of the invention, the composition further includes surface modified inorganic nanoparticles.
摘要:
An economic, optically transmissive, stain and ink repellent, durable low refractive index fluoropolymer composition for use in an antireflection film or coupled to an optical display. In one aspect of the invention, the composition is formed from the reaction product of a fluoropolymer or reactive fluoropolymer, an amino silane ester coupling agent or ester equivalent, a multi-olefinic crosslinker, and optional surface modified inorganic particles or sol gel precursors.
摘要:
An economic, optically transmissive, stain and ink repellent, durable low refractive index fluoropolymer composition for use in an antireflection film or coupled to an optical display. In one aspect of the invention, the composition is formed from the reaction product of a fluoropolymer, a C═C double bond group containing silane ester agent, and an optional multi-olefinic crosslinker. In another aspect of the invention, the composition further includes surface modified inorganic nanoparticles. In another aspect, the multi-olefinic crosslinker is an alkoxysilyl-containing multi-olefinic crosslinker.
摘要:
The present application is directed to a method of making an article. The method comprises coating a composition to a surface of a substrate. The coating composition comprises an aqueous continuous liquid phase, a silica nano-particle dispersed in the aqueous continuous liquid phase, and a polymer latex dispersion. The coated substrate is then heated to at least 300° C.
摘要:
The invention features a coating composition that comprises a non-urethane acrylate or methacrylate compound in combination with a fluorochemical. Typically, the non-urethane (meth)acrylate is an aliphatic or aromatic (meth)acrylate compound and the fluorochemical typically comprises a monofunctional (per)fluoropolyether (meth)acrylate compound. The coating compositions can provide a protective topcoat layer to a variety of substrates, including wood and vinyl.
摘要:
A coating composition which imparts antifog, antireflective, easy-cleaning, and/or antistatic properties to substrates coated therewith. The coating compositions utilize nanoparticles funtionalized with amine groups and/or protected amine groups, and amine-reactive groups.
摘要:
A method is provided for obtaining crosslinked polymers having pendent sulfonic acid groups by crosslinking through the sulfonic acid groups or their precursors with aromatic crosslinkers or aromatic pendent crosslinking groups to form aromatic sulfones. Such crosslinked polymers may be used to make polymer electrolyte membranes (PEM's) that may be used in electrolytic cells such as fuel cells.
摘要:
Fluorocarbon- and urethane-(meth)acryl-containing additives and hardcoats. The hardcoats are particularly useful as a surface layer on an optical device.