摘要:
The object of the present invention is to provide a compound having a glucokinase-activating effect.A pharmaceutical composition comprising a compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein X means a nitrogen atom or CR6, wherein R6 means a hydrogen atom or a halogen atom; R1 means a hydrogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or a C1-C6 alkylthio group; R2 means a hydrogen atom or a fluorine atom; R3 means a hydrogen atom or a C1-C6 alkyl group; and one of R4 and R5 means a hydrogen atom or a C1-C6 alkyl group, and the other means a C1-C6 alkylenecarboxylic acid, a C1-C6 alkylsulfonyl group, a C1-C6 alkylcarbonyl group, or CONH2.
摘要:
A method is described for starting an internal combustion engine having an E-machine coupled to it in a motor vehicle, after the input of a certain torque command at a drive control of the internal combustion engine, the internal combustion engine being accelerated for the start by the E-machine, and the internal combustion engine being set by the drive control, via actuators, to specified characteristics values for the start. To reduce exhaust gas emissions at the start of the internal combustion engine, the internal combustion engine is accelerated by the E-machine, without the injection of fuel, until the engine torque that is able to be implemented by the internal combustion engine, essentially corresponds to the torque command, and the injection of fuel into the internal combustion engine is only then released.
摘要:
The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A1 and A2 each independently represent an optionally substituted C1-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR4, CO, CO2, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR4, SO or SO2;
摘要:
The invention relates to a craft comprising an energy storage system of the RFCS (regenerative fuel cell system) type and a system for pressurizing the propellants used for propulsion. The craft also comprises a plurality of means (31 to 38) for coupling the tanks of the fuel cell to the propellant-pressurizing tanks of the propulsion system of the craft when the tanks of the propellant-pressurizing system are no longer used.The invention also relates to the method of coupling the tanks of the propellant-pressurizing means to the energy storage system.The invention applies particularly to telecommunication satellites and more generally to spacecraft.
摘要:
A mounting plate for electronic components, including cooling conduits that are integrated into a plate body and that are traversed by a coolant, a fixing device for mounting electronic components that are to be cooled being located on the plate body. The mounting plate has the fixing device including at least one first groove with an approximately C-shaped cross-section, which extends in a linear manner in the extension direction of the mounting plate. At least one screw nut is inserted and locked against torsion in the groove in order to form a screw connection with an electronic component.
摘要:
The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A1 and A2 each independently represent an optionally substituted C1-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR4, CO, CO2, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR4, SO or SO2;
摘要:
The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A1 and A2 each independently represent an optionally substituted C1-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR4, CO, CO, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR4, SO or SO2.
摘要翻译:本发明涉及通式(I)的化合物的用途:其中在式(I)中,R为H,烷基,环烷基,芳基或杂芳基; R 1是H,烷基,环烷基,芳基或杂芳基; R 2是H,烷基,环烷基,芳基或杂芳基; A 1和A 2各自独立地表示任选取代的C 1 -C 20 -C 20 - 烷基,其可以含有 一个或多个Z基团或可以含有一个或多个基团X的单环或多环任选取代的芳族或非芳族环系统,并且在多环系统的情况下,所述体系包含至少一个 芳香环 Z选自S,O,N,NR 4,CO,CO,CS,SO或SO 2 X选自S ,O,N,NR 4,SO或SO 2。
摘要:
The present invention relates to the use of compounds of the general Formula (1): wherein in Formula (1), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A1 and A2 each independently represent an optionally substituted C1-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR4, CO, CO2, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR4, SO or SO2.
摘要翻译:本发明涉及通式(1)的化合物的用途:其中在式(1)中,R为H,烷基,环烷基,芳基或杂芳基; R 1是H,烷基,环烷基,芳基或杂芳基; R 2是H,烷基,环烷基,芳基或杂芳基; A 1和A 2各自独立地表示任选取代的C 1 -C 20 -C 20 - 烷基,其可以含有 一个或多个Z基团或可以含有一个或多个基团X的单环或多环任选取代的芳族或非芳族环系统,并且在多环系统的情况下,所述体系包含至少一个 芳香环 Z选自S,O,N,NR 4,CO,CO 2,CS,SO或SO 2 X 选自S,O,N,NR 4,SO或SO 2。
摘要:
A patient device (PD) for wireless data communication with an implant. The PD can be at least in an unpaired state or a paired state. In the paired state the PD is paired to a specific implant specified by an implant's identification code (IIC). The IIC is stored in PD memory. Automatic pairing of the PD to a specific implant is performed upon receiving an incoming data packet containing an IIC when the PD is in its unpaired state with no valid IIC stored in memory. Thus, the PD is tentatively paired to an implant identified by the IIC contained in the incoming data packet by storing the IIC in the memory. Tentative pairing is cancelled if no further communication occurs within a predetermined period of time. A soft paired state is entered if further data communication does occur.
摘要:
Carbon monoxide is generated carbon monoxide, in a conversion stage (DR), from a hydrocarbon-containing feed (1, 2), and also steam and/or carbon dioxide (CO2), resulting in the formation of a carbon monoxide (CO)—, hydrogen (H2)— and methane (CH4)-containing synthesis gas (3). The synthesis gas is subsequently fed to a fractionation device (Z) for separating off at least one hydrogen-rich fraction (7, 9) and one methane-rich fraction (10) and also a carbon monoxide product (6). The methane-rich fraction (10) separated off in the fractionation device (Z) is recirculated as feed (M feed) upstream of the conversion stage (DR).
摘要翻译:一氧化碳在转化阶段(DR),来自含烃进料(1,2)以及蒸汽和/或二氧化碳(CO 2 H 2)中产生一氧化碳,导致 形成一氧化碳(CO) - ,氢(H 2 H 2) - 和甲烷(CH 4 SO 4)的合成气(3)。 随后将合成气送入分馏装置(Z)以分离出至少一个富氢馏分(7,9)和一个富含甲烷的馏分(10)以及一氧化碳产物(6)。 在分馏装置(Z)中分离的富甲馏分(10)作为进料(M进料)在转化级(DR)的上游再循环。