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19 条记录 (耗时 0.076 秒)

    Anti-microbial device and method for its manufacture
    3.
    发明授权
    Anti-microbial device and method for its manufacture 有权

    公开(公告)号：US11129924B2

    公开(公告)日：2021-09-28

    申请号：US16776980

    申请日：2020-01-30

    申请人： NANOVIS, LLC

    发明人： Matthew Hedrick ,  Chang Yao

    IPC分类号： A61L27/54 ,  C23C22/05 ,  C25D11/02 ,  C23C22/78 ,  A61L27/04 ,  A61L27/30 ,  C25D11/26 ,  C25D11/34 ,  C09D1/00 ,  C09D7/61 ,  C04B35/447 ,  C04B35/622 ,  C09D5/14

    摘要： An antimicrobial medical device that includes a substrate having a metal surface that is made from a metal or metal alloy that may include stainless steel, cobalt, and titanium. Disposed on the metal surface is a first antimicrobial oxide layer that includes an antimicrobial metal that may include silver, copper, and zinc, and combinations thereof. The atoms of antimicrobial metal in the first antimicrobial oxide layer are of a first concentration. The first antimicrobial oxide layer is positioned in a direction opposite that of the metal surface. The device further includes a second antimicrobial oxide layer that includes an antimicrobial metal that may be silver, copper, and zinc, and combinations thereof. The atoms of the antimicrobial metal present in the second antimicrobial oxide layer are of a second concentration. The first concentration and the second concentration are not equal. Methods for making the antimicrobial medical device are also disclosed.

    METHOD TO ENHANCE OSTEOBLAST FUNCTIONALITY AND MEASURE ELECTROCHEMICAL PROPERTIES FOR A MEDICAL IMPLANT
    5.
    发明申请
    METHOD TO ENHANCE OSTEOBLAST FUNCTIONALITY AND MEASURE ELECTROCHEMICAL PROPERTIES FOR A MEDICAL IMPLANT 审中-公开
    增强机械功能的方法和测量医疗植入物的电化学性质

    公开(公告)号：US20110301716A1

    公开(公告)日：2011-12-08

    申请号：US12668706

    申请日：2008-07-10

    申请人： Sirinrath Sirivisoot ,  Chang Yao ,  Xingcheng Xiao ,  Brian Sheldon ,  Thomas Webster

    发明人： Sirinrath Sirivisoot ,  Chang Yao ,  Xingcheng Xiao ,  Brian Sheldon ,  Thomas Webster

    IPC分类号： A61F2/28 ,  B05D7/14 ,  C23C28/00 ,  A61N1/00 ,  B05D5/00 ,  C25D11/02 ,  B82Y40/00

    CPC分类号： A61L27/50 ,  A61L2400/18

    摘要： A method to enhance osteoblast functionality of a medical implant. The method may include obtaining the medical implant and treating a surface of the medical implant to modify the surface characteristics causing increase functionality of adjacent positioned osteoblasts. A method of increasing cellular activity of a medical implant is also disclosed. A medical device having enhanced cytocompatibility capabilities includes a metallic substrate with an outer surface. Attached to the outer surface is a composition of nanosized structures. A biosensor for use with a medical device, includes an electrode that is attached to an outer surface of the medical device. The biosensor measures electrochemical changes adjacent to the medical implant. Further, a method of manufacturing a medical implant with a biosensor for use in vivo and a method of integrating a biosensor with a medical implant for use in monitoring conductivity and electrochemical changes adjacent to the medical implant are disclosed.

    摘要翻译： 一种增强医学植入物成骨细胞功能的方法。 该方法可以包括获得医疗植入物并处理医用植入物的表面以改变表面特征，导致相邻定位的成骨细胞增加功能。 还公开了增加医疗植入物的细胞活性的方法。 具有增强的细胞相容性能力的医疗装置包括具有外表面的金属基底。 附着于外表面的是纳米尺寸结构的组合物。 用于医疗装置的生物传感器包括附着在医疗装置的外表面上的电极。 生物传感器测量与医用植入物相邻的电化学变化。 此外，公开了一种制造具有用于体内的生物传感器的医用植入物的方法以及将生物传感器与医用植入物整合的方法，用于监测与医疗植入物相邻的导电性和电化学变化。

    Anti-microbial device and method for its manufacture
    6.
    发明授权
    Anti-microbial device and method for its manufacture 有权

    公开(公告)号：US10576186B2

    公开(公告)日：2020-03-03

    申请号：US15276048

    申请日：2016-09-26

    申请人： NANOVIS, LLC

    发明人： Matthew Hedrick ,  Chang Yao

    IPC分类号： A61L27/54 ,  C23C22/05 ,  C25D11/02 ,  C23C22/78 ,  A61L27/04 ,  A61L27/30 ,  C25D11/26 ,  C25D11/34 ,  C09D1/00 ,  C09D7/61 ,  C04B35/447 ,  C04B35/622 ,  C09D5/14

    摘要： An antimicrobial medical device that includes a substrate having a metal surface that is made from a metal or metal alloy that may include stainless steel, cobalt, and titanium. Disposed on the metal surface is a first antimicrobial oxide layer that includes an antimicrobial metal that may include silver, copper, and zinc, and combinations thereof. The atoms of antimicrobial metal in the first antimicrobial oxide layer are of a first concentration. The first antimicrobial oxide layer is positioned in a direction opposite that of the metal surface. The device further includes a second antimicrobial oxide layer that includes an antimicrobial metal that may be silver, copper, and zinc, and combinations thereof. The atoms of the antimicrobial metal present in the second antimicrobial oxide layer are of a second concentration. The first concentration and the second concentration are not equal. Methods for making the antimicrobial medical device are also disclosed.

    Farby-perot laser with wavelength control
    8.
    发明申请
    Farby-perot laser with wavelength control 有权
    Farby-perot激光器具有波长控制

    公开(公告)号：US20020196826A1

    公开(公告)日：2002-12-26

    申请号：US10064002

    申请日：2002-06-03

    申请人： Nanovis LLC

    发明人： Robert J. Mears ,  Augustin Yiptong ,  Adam D. Cohen

    IPC分类号： H01S005/00 ,  H01S003/063 ,  H01S003/08

    CPC分类号： G02B6/02085 ,  G02B5/18 ,  G02B6/02057 ,  G02B6/122 ,  G02B2006/12107 ,  G02F1/225 ,  G02F1/2252 ,  G02F1/3136 ,  G02F1/3517 ,  G02F1/3521 ,  G02F1/3558 ,  G02F2001/212 ,  G02F2201/30 ,  G02F2201/307 ,  H01S5/1206 ,  H01S5/125 ,  H01S5/18361

    摘要： A laser device, in particular a semiconductor laser, emitting optical radiation with a defined mode pattern can be produced from a standard Fabry-Perot (FP) laser by post-processing at the wafer level, i.e. before the wafer is separated into individual dies by cleaving/dicing. A sub-cavity is formed within the FP laser cavity. The sub-cavity has a predetermined length and is located between the FP facets. An aperiodic grating composed of a small number of contrast elements, typically less than 10, with predetermined inter-element separations and predetermined spacings relative to the sub-cavity is formed on or in the optical waveguide. The inter-element separations and the spacings relative to the sub-cavity produce a filtering function of the aperiodic grating for optical radiation propagating in the waveguide. The laser device is suitable for telecommunications applications due to its high side-mode-suppression ratio and narrow-linewidth.

    摘要翻译： 可以通过在晶片级进行后处理，即在晶片被分离成单独的裸片之前，从标准的法布里 - 珀罗（FP）激光器产生具有限定模式图案的发射光辐射的激光装置，特别是半导体激光器 切割/切割 在FP激光腔内形成子腔。 子腔具有预定长度并且位于FP面之间。 在光波导上或光波导中形成有由少量对比元件（通常小于10个）组成的非周期性光栅，具有相对于子腔的预定的元件间隔离和预定间隔。 元件间分离和相对于子腔的间隔产生用于波导中传播的光辐射的非周期光栅的滤波函数。 激光器件由于具有高侧模抑制比和窄线宽，适用于电信应用。