公开(公告)号：US20180320242A1

公开(公告)日：2018-11-08

申请号：US15772571

申请日：2016-11-07

申请人： UNIVERSITY OF COPENHAGEN

发明人： Mette Nicolaisen ,  Stefan Olsson ,  Ole Nybro ,  Behnoushsadat Ghodsalavi ,  Deborah Jean Springer ,  Michael A. Furlan

IPC分类号： C12R1/80 ,  A01N63/04 ,  A01H3/00 ,  C12R1/07

CPC分类号： C12R1/80 ,  A01C1/06 ,  A01H3/00 ,  A01H6/20 ,  A01H6/4684 ,  A01H6/54 ,  A01N63/00 ,  A01N63/04 ,  C12N1/14 ,  C12N1/20 ,  C12R1/07 ,  A01N25/00

摘要： Disclosed are methods for identifying microbes that associate with other microbes, and possess new or improved characteristics. Also disclosed are microbes isolated using the methods. Also disclosed are methods for using the microbes.

公开(公告)号：US09994804B2

公开(公告)日：2018-06-12

申请号：US14247134

申请日：2014-04-07

申请人： Menon Renewable Products, Inc.

发明人： Suresh M. Menon ,  Arul Victor Suresh ,  Samantha S. Orchard ,  Kashinatham Alisala ,  Jagadish C. Sircar ,  Sara Ingegard Hash

IPC分类号： A23K1/18 ,  A23K1/00 ,  A23L1/28 ,  A23L1/22 ,  A23C9/12 ,  A23C17/00 ,  A23C21/00 ,  A23B7/10 ,  A23F3/00 ,  C12M1/00 ,  C11B1/10 ,  C11C3/00 ,  C12M1/06 ,  C12N1/14 ,  C12P5/00 ,  C12P5/02 ,  C12P7/64 ,  C12R1/645 ,  C12M1/12 ,  C12R1/80 ,  A23K10/12 ,  A23K20/158 ,  A23K50/10 ,  A23K50/80 ,  A01N63/04 ,  A23K40/20 ,  A23K20/147 ,  A23K20/142 ,  A23K50/75 ,  A23K50/42 ,  A23L33/12

CPC分类号： C12M21/12 ,  A01N63/04 ,  A23K10/12 ,  A23K20/142 ,  A23K20/147 ,  A23K20/158 ,  A23K40/20 ,  A23K50/10 ,  A23K50/42 ,  A23K50/75 ,  A23K50/80 ,  A23L33/12 ,  A23V2002/00 ,  C11B1/10 ,  C11C3/003 ,  C12M25/02 ,  C12M27/02 ,  C12M27/20 ,  C12N1/14 ,  C12P5/005 ,  C12P5/02 ,  C12P7/6463 ,  C12P7/6481 ,  C12P2203/00 ,  C12R1/645 ,  C12R1/80 ,  Y02A40/818 ,  Y10S426/805 ,  Y10S426/807

摘要： Disclosed herein are compositions comprising an isolated cellulose degrading fungus. Also disclosed are culture compositions and bioreactor compositions comprising the cellulose degrading fungus. Further described herein are filtration and extraction devices comprising the cellulose degrading fungus. Still further disclosed are bioprocessing facilities for and methods for producing co-products resulting from one or more bioprocesses of the cellulose degrading fungus.

公开(公告)号：US20120058550A1

公开(公告)日：2012-03-08

申请号：US13102965

申请日：2011-05-06

申请人： Suresh M. Menon ,  Samantha S. Orchard ,  Jessica Badger ,  David Lipson ,  Sara Guidi ,  David Newman

发明人： Suresh M. Menon ,  Samantha S. Orchard ,  Jessica Badger ,  David Lipson ,  Sara Guidi ,  David Newman

IPC分类号： C12M1/00 ,  C12M1/12

CPC分类号： C12M21/12 ,  A01N63/04 ,  A23K10/12 ,  A23K20/142 ,  A23K20/147 ,  A23K20/158 ,  A23K40/20 ,  A23K50/10 ,  A23K50/42 ,  A23K50/75 ,  A23K50/80 ,  A23L33/12 ,  A23V2002/00 ,  C11B1/10 ,  C11C3/003 ,  C12M25/02 ,  C12M27/02 ,  C12M27/20 ,  C12N1/14 ,  C12P5/005 ,  C12P5/02 ,  C12P7/6463 ,  C12P7/6481 ,  C12P2203/00 ,  C12R1/645 ,  C12R1/80 ,  Y02A40/818 ,  Y10S426/805 ,  Y10S426/807

摘要： Disclosed herein are compositions comprising an isolated cellulose degrading fungus. Also disclosed are culture compositions and bioreactor compositions comprising the cellulose degrading fungus. Further described herein are filtration and extraction devices comprising the cellulose degrading fungus. Still further disclosed are bioprocessing facilities for and methods for producing co-products resulting from one or more bioprocesses of the cellulose degrading fungus.

摘要翻译： 本文公开了包含分离的降解纤维素的真菌的组合物。 还公开了包含纤维素降解菌的培养组合物和生物反应器组合物。 本文进一步描述的是包含纤维素降解菌的过滤和提取装置。 还公开了生物处理设备和用于生产由一种或多种纤维素降解真菌生物处理产生的副产物的方法。

公开(公告)号：US20120058510A1

公开(公告)日：2012-03-08

申请号：US13318850

申请日：2010-05-07

申请人： Neville Marshall Fish ,  Lone Brønd Miller

发明人： Neville Marshall Fish ,  Lone Brønd Miller

IPC分类号： C12P1/00 ,  C12N9/42 ,  C12C7/04 ,  A23L1/105 ,  C12C7/17 ,  A23L2/02 ,  C12G1/022 ,  C12N9/24 ,  C12C7/165

CPC分类号： C12N9/2437 ,  A23L2/02 ,  C12C5/004 ,  C12C5/006 ,  C12C7/04 ,  C12G3/12 ,  C12N1/14 ,  C12N9/244 ,  C12N9/2482 ,  C12P7/06 ,  C12R1/80 ,  C12R1/885 ,  C12Y302/01004 ,  C12Y302/01006 ,  C12Y302/01008 ,  Y02E50/17

摘要： The invention relates to an improved enzyme complex having a plurality of enzyme activities of an expression product obtained by fermentation of the genus Trichoderma in combination with one or more enzymes of a different fungus strain.

公开(公告)号：US08043844B2

公开(公告)日：2011-10-25

申请号：US11154793

申请日：2005-06-16

申请人： Alain Sabatier ,  Neville Marshall Fish ,  Nigel Paterson Haigh

发明人： Alain Sabatier ,  Neville Marshall Fish ,  Nigel Paterson Haigh

IPC分类号： C12N1/00

CPC分类号： C12R1/80 ,  A23K20/189 ,  A23K30/18 ,  A23K50/30 ,  C12N9/18 ,  C12N9/2434 ,  C12N9/2437 ,  C12N9/248 ,  C12Y301/01073 ,  C12Y302/01008 ,  Y02P60/877

摘要： The present invention relates to a micro-organism, Penicillium funiculosum, to enzyme mixtures obtained from it and nucleic acid sequences thereto.

摘要翻译： 本发明涉及微生物，青霉菌，从其获得的酶混合物及其核酸序列。

公开(公告)号：US20080227164A1

公开(公告)日：2008-09-18

申请号：US11576712

申请日：2004-10-05

申请人： Surekha Prabhu ,  Pinakee Devi Sharma ,  Sanjay Tiwari ,  Ramakrishnan Melarkode ,  Ramavana Gururaja ,  Shrikumar Suryanarayan

发明人： Surekha Prabhu ,  Pinakee Devi Sharma ,  Sanjay Tiwari ,  Ramakrishnan Melarkode ,  Ramavana Gururaja ,  Shrikumar Suryanarayan

IPC分类号： C12P17/04 ,  C12N1/14

CPC分类号： C12P17/04 ,  C12R1/80 ,  Y10S435/933

摘要： The present invention discloses the manufacture of MPA by fermentation under optimal fermentation parameters using a new strain of Penicillium arenicola.

摘要翻译： 本发明公开了使用新的青霉菌菌株在最佳发酵参数下通过发酵制备MPA。

公开(公告)号：US20070105883A1

公开(公告)日：2007-05-10

申请号：US10551417

申请日：2004-03-29

申请人： Nobuaki Kushida ,  Naoko Watanabe ,  Takashi Yaguchi ,  Fumikazu Yokoyama ,  Goh Tsujiuchi ,  Takako Okuda

发明人： Nobuaki Kushida ,  Naoko Watanabe ,  Takashi Yaguchi ,  Fumikazu Yokoyama ,  Goh Tsujiuchi ,  Takako Okuda

IPC分类号： A61K31/4747 ,  C07D471/10

CPC分类号： C07D471/20 ,  C12P17/182 ,  C12R1/80

摘要： This invention provides novel PF1270A substance, PF1270B substance and PF1270C substance represented by the following formula (1) or pharmaceutically acceptable salts thereof, a method for producing the same and a pharmaceutical composition which comprises at least one of the same as the active ingredient. Since a group of the PF1270 substances of the invention show high affinity for histamine H3 receptor, they are expected as novel histamine H3 receptor ligands useful as medicaments.

摘要翻译： 本发明提供由下式（1）表示的新型PF1270A物质，PF1270B物质和PF1270C物质或其药学上可接受的盐，其制备方法和含有至少一种作为活性成分的药物组合物。 由于本发明的一组PF1270物质对组胺H 3 H 3受体表现出高亲和力，所以它们被认为是用作药物的新型组胺H 3 N 3受体配体。

公开(公告)号：US20050227344A1

公开(公告)日：2005-10-13

申请号：US11154793

申请日：2005-06-16

申请人： Alain Sabatier ,  Neville Fish ,  Nigel Haigh

发明人： Alain Sabatier ,  Neville Fish ,  Nigel Haigh

IPC分类号： A23K1/165 ,  A23K1/18 ,  A23K3/03 ,  C12N1/14 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/16 ,  C12N9/18 ,  C12N9/24 ,  C12N9/42 ,  C12N11/18 ,  C12N15/09 ,  C12R1/80 ,  C12N1/16

CPC分类号： C12R1/80 ,  A23K20/189 ,  A23K30/18 ,  A23K50/30 ,  C12N9/18 ,  C12N9/2434 ,  C12N9/2437 ,  C12N9/248 ,  C12Y301/01073 ,  C12Y302/01008 ,  Y02P60/877

摘要： The present invention relates to novel micro-organism, Penicillium funiculosum, to new enzymes mixture obtained from it and nucleic acid sequences thereto.

摘要翻译： 本发明涉及新颖的微生物，青霉菌，从其获得的新的酶混合物和其核酸序列。

公开(公告)号：US06440709B1

公开(公告)日：2002-08-27

申请号：US09651812

申请日：2000-08-30

申请人： Hideo Hirai ,  Toshio Ichiba ,  Hiroko Tonai

发明人： Hideo Hirai ,  Toshio Ichiba ,  Hiroko Tonai

IPC分类号： C12P1706

CPC分类号： C12R1/80 ,  C07D311/76 ,  C12P17/06

摘要： This invention relates to the isochroman compound of formula (I) and its pharmaceutically acceptable salts, which are useful as an amyloid aggregation inhibitor and for treating Alzheimer's disease. This invention also relates to processes for producing the isochroman compound, which comprises cultivating Penicillium simplicissimum FERM BP-6357 and then isolating the isochroman compound from the fermentation broth. The present invention also relates to a pharmaceutical composition comprising the isochroman compound.

摘要翻译： 本发明涉及式（I）的异苯并二氢吡喃化合物及其药学上可接受的盐，其可用作淀粉样聚集抑制剂并用于治疗阿尔茨海默氏病。 本发明还涉及异苯并二氢吡喃化合物的制备方法，该方法包括培养简单微生物FERM BP-6357的青霉菌，然后从发酵液中分离异色素化合物。 本发明还涉及包含异色满化合物的药物组合物。

公开(公告)号：US06323021B1

公开(公告)日：2001-11-27

申请号：US09334739

申请日：1999-06-17

申请人： Yun-Ping Wang ,  Yen-Chun Chen ,  Weimao Chang ,  Chi-Luan Lin

发明人： Yun-Ping Wang ,  Yen-Chun Chen ,  Weimao Chang ,  Chi-Luan Lin

IPC分类号： C12N114

CPC分类号： C12R1/80

摘要： A novel microorganism, Penicillium citrinum CCRC 930024 and a process of using the microorganism for the production of compactin comprising cultivating Penicillium citrinum CCRC 930024 in a fermentation medium and recovering compactin from the fermentation broth are disclosed.

摘要翻译： 公开了一种新型微生物，青霉菌CCRC930024，以及使用微生物生产压实蛋白的方法，包括在发酵培养基中培养柑桔青霉CCRC 930024并从发酵液中回收贝伐菌素。