公开(公告)号：US09476809B2

公开(公告)日：2016-10-25

申请号：US12527443

申请日：2008-02-13

申请人： Tobias Krebs

发明人： Tobias Krebs

IPC分类号： C12M1/00 ,  C12M3/00 ,  G01N1/28 ,  B01F3/04 ,  B01F5/04 ,  G01N35/00

CPC分类号： G01N1/28 ,  B01F3/0446 ,  B01F5/0471 ,  C12M23/40 ,  C12M29/06 ,  G01N2035/00178

摘要： Gassing or fumigation apparatus comprising a one-piece specimen receptacle block including at least two specimen receptacles formed therein and a fluid supply device formed therein for the at least two specimen receptacles, and a gassing or fumigation head for supplying gassing or fumigation medium, which gassing or fumigation head is connected to the specimen receptacle block, comprises a gassing or fumigation medium outlet for each of the at least two specimen receptacles and a device formed therein for conducting gassing medium to the gassing or fumigation medium outlets, and gassing or fumigation system including such a gassing or fumigation apparatus.

摘要翻译： 放气或熏蒸装置包括一体式样品容器块，其包括形成在其中的至少两个样品容器和形成在其中的用于至少两个样品容器的流体供应装置，以及用于提供放气或熏蒸介质的放气或熏蒸头， 或熏蒸头连接到样品容器块，包括用于至少两个样品容器中的每一个的气体或熏蒸介质出口，以及其中形成的用于将放气介质输送到放气或熏蒸介质出口的装置，以及气体或熏蒸系统，包括 这样的放气或熏蒸装置。

公开(公告)号：US20020196435A1

公开(公告)日：2002-12-26

申请号：US09989684

申请日：2001-11-20

发明人： David Samuel Cohen ,  Yih Far Chen ,  Lynn Kim ,  Chih-Hsin Shih

IPC分类号： G01N001/10

CPC分类号： G01N15/05 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2300/0806 ,  B01L2300/0861 ,  B01L2300/168 ,  B01L2400/0409 ,  G01N15/0272 ,  G01N15/042 ,  G01N21/07 ,  G01N33/491 ,  G01N35/00069 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/0092 ,  G01N2015/045 ,  G01N2035/00178 ,  G01N2035/00504

摘要： Rotating apparatus has a separation zone structure having solid components spaced apart to form gaps. The gaps are large enough to allow disperse particles to change position relative to the center of rotation by passing through the separation zone structure. The gaps are too small to allow particle agglutinants to pass through the separation zone structure.

摘要翻译： 旋转装置具有分离区结构，其具有间隔开的固体组分以形成间隙。 间隙足够大以允许分散颗粒通过穿过分离区结构相对于旋转中心改变位置。 间隙太小，不能使颗粒凝集物通过分离区结构。

公开(公告)号：US20230417642A1

公开(公告)日：2023-12-28

申请号：US18037227

申请日：2021-11-17

申请人： LTS Lohmann Therapie-Systeme AG

发明人： Helena Gallinger ,  Andreas Koch

IPC分类号： G01N13/00 ,  G01N33/15 ,  G01N1/44 ,  G01K5/48 ,  F28D1/06 ,  G09B23/28 ,  G05D23/19 ,  G05D23/27

CPC分类号： G01N13/00 ,  G01N33/15 ,  G01N1/44 ,  G01K5/48 ,  F28D1/06 ,  G09B23/28 ,  G05D23/1919 ,  G05D23/27 ,  G01N2013/003 ,  G01N2035/00178

摘要： A temperature control system for a diffusion cell. The temperature control system includes a cell head and a temperature control device connected to the cell head. Moreover, a diffusion cell having such a temperature control system. Furthermore a diffusion cell system having such a temperature control system or such a diffusion cell. Finally, a method for controlling the temperature of a cell head of a diffusion cell, including introducing the temperature control fluid into the cell head.

公开(公告)号：US20180193843A1

公开(公告)日：2018-07-12

申请号：US15866073

申请日：2018-01-09

申请人： MRIGlobal

发明人： Jonathan L. Jacobs ,  Joseph A. Russell ,  Jacob R. Aspinwall

IPC分类号： B01L9/02 ,  C12Q1/04 ,  B01L7/00 ,  C12M1/00 ,  B01L3/00 ,  C12Q1/24 ,  G01N15/04 ,  G01N21/64 ,  G01N33/483 ,  G01N33/50 ,  G01N1/00 ,  G01N15/00

CPC分类号： B01L9/02 ,  A45C11/20 ,  A45C15/00 ,  A45F3/04 ,  A45F4/02 ,  B01L1/52 ,  B01L3/0275 ,  B01L3/502 ,  B01L3/5082 ,  B01L7/52 ,  B01L9/06 ,  B01L9/543 ,  B01L2200/028 ,  B01L2200/16 ,  B01L2200/18 ,  B01L2300/046 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0877 ,  B01L2300/18 ,  B01L2400/0424 ,  B01L2400/0487 ,  C12M41/14 ,  C12Q1/04 ,  C12Q1/24 ,  G01N15/04 ,  G01N21/6428 ,  G01N33/483 ,  G01N33/50 ,  G01N35/00871 ,  G01N2001/002 ,  G01N2015/0019 ,  G01N2015/0065 ,  G01N2035/00178 ,  G01N2035/00326 ,  G01N2035/00881 ,  G01N2800/00 ,  G01N2800/26

摘要： A mobile field-deployable laboratory to more conveniently enable the detecting, sequencing and analyzing of biological agents at the point-of-need. This device enables field operators to go from sample to actionable information in the field without the need for an internet connection or grid-based power. The mobile laboratory can be configured either in a single backpack configuration or in a footlocker configuration wherein both configurations include a plurality of different compartments specifically configured for holding all of the necessary equipment for successfully extracting, amplifying, sequencing and characterizing specific viruses, pathogens and other bacteria directly in the field including an integrated power supply for providing power to the relevant components for up to 72 hours of continuous use without the need for any external power source, a cold storage compartment for frozen and chilled critical reagents, a PCR detection system, a DNA/RNA sequencing system, a bioinformatics analysis system, a centrifuge, and a deployable workbench area which provides a stable workstation when either the backpack or footlocker configuration is deployed.

公开(公告)号：US11796553B2

公开(公告)日：2023-10-24

申请号：US17265726

申请日：2019-06-27

申请人： Hitachi High-Tech Corporation

发明人： Nobuhiko Sasaki ,  Takanori Sawada ,  Toshiyuki Shimamori ,  Chie Yabutani

IPC分类号： G01N35/10 ,  G01N35/00

CPC分类号： G01N35/1011 ,  G01N35/1002 ,  G01N2035/00178

摘要： A chemical dispensing mechanism detects the liquid surface of a chemical including a chemical container mounted on a chemical disk. A calculation control unit controls the operation of the chemical dispensing mechanism. The calculation control unit performs a first raising operation, in which a chemical stored in the chemical container is suctioned by the chemical dispensing mechanism, which is then raised up to a first bubble detection position, determines whether a liquid surface is present, and outputs an alert indicating the presence of a bubble on the liquid surface when the liquid surface has been determined to be absent. The first bubble detection position is when the tip of a dispensing nozzle of the chemical dispensing mechanism remains inside the liquid when there are no bubbles present on the liquid surface, and is exposed from the inside of the liquid when there are bubbles present on the liquid surface.

公开(公告)号：US06743632B2

公开(公告)日：2004-06-01

申请号：US09805057

申请日：2001-03-14

申请人： Mark S. F. Clarke ,  Daniel L. Feeback

发明人： Mark S. F. Clarke ,  Daniel L. Feeback

IPC分类号： G01N3500

CPC分类号： B01L3/502707 ,  B01L3/502723 ,  B01L3/50273 ,  B01L9/527 ,  B01L2200/0689 ,  B01L2300/0803 ,  B01L2400/0409 ,  B01L2400/0633 ,  G01N1/31 ,  G01N21/07 ,  G01N2035/00178 ,  G01N2035/00336 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/112499

摘要： Centrifugal analyzer and method for staining biological or non-biological samples in microgravity, wherein the method utilizes an increase in weight of a fluid sample as a function of g-load, to overcome cohesive and frictional forces from preventing its movement in a preselected direction. Apparatus is characterized by plural specimen reservoirs and channels in a slide, each channel being of differing cross-section, wherein respective samples are selectively dispensed, from the reservoirs in response to an imposed g-factor, precedent to sample staining. Within the method, one thus employs microscope slides which define channels, each being of a differing cross-section dimension relative to others. In combination therewith, centrifugal slide mounting apparatus controllably imposes g-vectors of differing magnitudes within a defined structure of the centrifuge such as a chip array.

摘要翻译： 用于在微重力中染色生物或非生物样品的离心分析仪和方法，其中所述方法利用作为g-载荷的函数的流体样品的重量增加，以克服粘性和摩擦力以防止其沿预选方向移动。 装置的特征在于载玻片中的多个样品储存器和通道，每个通道具有不同的横截面，其中响应于施加的g因子，样品染色的先例，从储存器中选择性地分配相应的样品。 在该方法中，因此使用限定通道的显微镜载玻片，每个通道相对于其它通道具有不同的横截面尺寸。 与此同时，离心式滑动安装装置可控制地将不同大小的g向量施加在离心机的限定结构内，例如芯片阵列。

公开(公告)号：US20020142470A1

公开(公告)日：2002-10-03

申请号：US09805057

申请日：2001-03-14

发明人： Mark S.F. Clarke ,  Daniel L. Feeback

IPC分类号： B04B013/00 ,  B04B005/12 ,  G01N001/30

CPC分类号： B01L3/502707 ,  B01L3/502723 ,  B01L3/50273 ,  B01L9/527 ,  B01L2200/0689 ,  B01L2300/0803 ,  B01L2400/0409 ,  B01L2400/0633 ,  G01N1/31 ,  G01N21/07 ,  G01N2035/00178 ,  G01N2035/00336 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/112499

摘要： Centrifugal analyzer and method for staining biological or non-biological samples in microgravity, wherein the method utilizes an increase in weight of a fluid sample as a function of g-load, to overcome cohesive and frictional forces from preventing its movement in a preselected direction. Apparatus is characterized by plural specimen reservoirs and channels in a slide, each channel being of differing cross-section, wherein respective samples are selectively dispensed, from the reservoirs in response to an imposed g-factor, precedent to sample staining. Within the method, one thus employs microscope slides which define channels, each being of a differing cross-section dimension relative to others. In combination therewith, centrifugal slide mounting apparatus controllably imposes g-vectors of differing magnitudes within a defined structure of the centrifuge such as a chip array.

摘要翻译： 用于在微重力中染色生物或非生物样品的离心分析仪和方法，其中所述方法利用作为g-载荷的函数的流体样品的重量增加，以克服粘性和摩擦力以防止其沿预选方向移动。 装置的特征在于载玻片中的多个样品储存器和通道，每个通道具有不同的横截面，其中响应于施加的g因子，样品染色的先例，从储存器中选择性地分配相应的样品。 在该方法中，因此使用限定通道的显微镜载玻片，每个通道相对于其它通道具有不同的横截面尺寸。 与此同时，离心式滑动安装装置可控制地将不同大小的g向量施加在离心机的限定结构内，例如芯片阵列。

公开(公告)号：US20150307293A1

公开(公告)日：2015-10-29

申请号：US14682688

申请日：2015-04-09

申请人： IDS CO., LTD.

发明人： Teruaki ITOH

IPC分类号： B65G57/16 ,  G01N35/00

CPC分类号： B65G57/165 ,  A61B10/007 ,  B65B35/50 ,  G01N35/0099 ,  G01N2035/00178 ,  G01N2035/00277

摘要： A container collecting device which stacks and collects containers each formed by closing a small-diameter side of a tapered cylinder. The container collecting device comprises that a guide cylinder having an inner diameter larger than the largest outer diameter of the container and extending in a gravity direction, and a supporter that supports the container at a lower end of the guide cylinder; and an actuator to move the container.

摘要翻译： 容器收集装置，其堆放和收集通过关闭锥形圆筒的小直径侧形成的容器。 容器收集装置包括具有大于容器的最大外径并且在重力方向上延伸的内径的引导筒和在引导筒的下端处支撑容器的支撑件; 以及用于移动容器的致动器。

公开(公告)号：US20100093067A1

公开(公告)日：2010-04-15

申请号：US12527443

申请日：2008-02-13

申请人： Tobias Krebs

发明人： Tobias Krebs

IPC分类号： G01N1/28

CPC分类号： G01N1/28 ,  B01F3/0446 ,  B01F5/0471 ,  C12M23/40 ,  C12M29/06 ,  G01N2035/00178

摘要： Gassing or fumigation apparatus comprising a one-piece specimen receptacle block including at least two specimen receptacles formed therein and a fluid supply device formed therein for the at least two specimen receptacles, and a gassing or fumigation head for supplying gassing or fumigation medium, which gassing or fumigation head is connected to the specimen receptacle block, comprises a gassing or fumigation medium outlet for each of the at least two specimen receptacles and a device formed therein for conducting gassing medium to the gassing or fumigation medium outlets, and gassing or fumigation system including such a gassing or fumigation apparatus.

摘要翻译： 放气或熏蒸装置包括一体式样品容器块，其包括形成在其中的至少两个样品容器和形成在其中的用于至少两个样品容器的流体供应装置，以及用于提供放气或熏蒸介质的放气或熏蒸头， 或熏蒸头连接到样品容器块，包括用于至少两个样品容器中的每一个的气体或熏蒸介质出口，以及其中形成的用于将放气介质输送到放气或熏蒸介质出口的装置，以及气体或熏蒸系统，包括 这样的放气或熏蒸装置。

公开(公告)号：US20050185569A1

公开(公告)日：2005-08-25

申请号：US10351604

申请日：2003-01-23

申请人： James Coombs ,  Kevin McIntyre ,  Mark Worthington

发明人： James Coombs ,  Kevin McIntyre ,  Mark Worthington

IPC分类号： G01N21/01 ,  G01N35/00 ,  G11B7/007 ,  G11B7/24

CPC分类号： G01N21/253 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/143 ,  B01L2300/021 ,  B01L2300/0806 ,  B01L2400/0409 ,  G01N35/00069 ,  G01N2035/00178

摘要： An optical analysis disc includes grooves defining corresponding laser-readable tracks and trigger marks that identify respective target regions on the disc. The trigger marks are implemented as a radial interruption of the grooves to thereby produce an increased reflection of a laser beam. There is also provided an optical analysis disc system including a trigger mechanism having a trigger detector adapted to detect interruptions in grooves of an optical analysis disc. A related method for triggering through interrupted grooves of an optical analysis disc includes detecting interruption in the grooves, generating an electrical reflection signal corresponding to the interruptions detected, and elaborating said reflection signal, so that to generate a trigger signal.

摘要翻译： 光学分析盘包括限定对应的激光可读轨迹的槽，以及标识盘上各个目标区域的触发标记。 触发标记被实现为凹槽的径向中断，从而产生激光束的增加的反射。 还提供了一种光学分析盘系统，其包括具有适于检测光学分析盘的凹槽中的中断的触发检测器的触发机构。 用于触发光学分析盘的中断凹槽的相关方法包括检测凹槽中的中断，产生与所检测到的中断相对应的电反射信号，并且阐述所述反射信号，以便产生触发信号。