公开(公告)号：US20240082605A1

公开(公告)日：2024-03-14

申请号：US18472034

申请日：2023-09-21

Applicant: RefleXion Medical, Inc.

Inventor： Yevgen VORONENKO ,  Jayakrishnan Janardhanan ,  Debashish Pal ,  Rostem Bassalow ,  Peter Demetri Olcott ,  Michael Kirk Owens

IPC: A61N5/10 ,  A61B6/00 ,  A61B6/03 ,  A61B6/04

CPC classification number: A61N5/1079 ,  A61B6/035 ,  A61B6/037 ,  A61B6/0407 ,  A61B6/4435 ,  A61B6/54 ,  A61N5/103 ,  A61N5/1045 ,  A61N5/1049 ,  A61N5/107 ,  A61N5/1071 ,  A61N5/1075 ,  A61N5/1081 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058 ,  A61N2005/1061 ,  A61N5/1068 ,  A61N2005/1072

Abstract: Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.

公开(公告)号：US11925510B2

公开(公告)日：2024-03-12

申请号：US17973386

申请日：2022-10-25

Applicant: URSUS Medical Designs LLC

Inventor： Sergei Koptenko ,  Thomas Hayes ,  Matthew Lyon

IPC: A61B8/06 ,  A61B8/00 ,  A61B8/08 ,  A61H31/00 ,  A61N5/10 ,  A61B17/00

CPC classification number: A61B8/56 ,  A61B8/06 ,  A61B8/4427 ,  A61B8/4472 ,  A61B8/4477 ,  A61B8/4488 ,  A61B8/462 ,  A61B8/485 ,  A61B8/488 ,  A61B8/5246 ,  A61H31/005 ,  A61N5/1049 ,  A61B8/4227 ,  A61B8/4281 ,  A61B2017/00106 ,  A61N2005/1058

Abstract: A distributed patient monitoring system comprises at least one standalone portable ultrasound imaging unit configured to be fixed to a stable position against the skin on a patient's body and capable of prolonged ultrasound data acquisition, including an ultrasound imaging array, transmit-receive circuitry, a beamformer, backend signal and image processing subsystem, power and communication subsystems, and a monitoring workstation connected to each standalone portable ultrasound imaging unit configured to request and receive ultrasound imaging information from each standalone portable ultrasound imaging unit, and configured to analyze and display acquired ultrasound information.

公开(公告)号：US11857807B2

公开(公告)日：2024-01-02

申请号：US16622050

申请日：2018-06-29

Applicant: Yoav Levy ,  Rafi De Picciotto ,  Javier Grinfeld ,  Eyal Zadicario

Inventor： Yoav Levy ,  Rafi De Picciotto ,  Javier Grinfeld ,  Eyal Zadicario

IPC: A61M37/00 ,  A61N7/00 ,  A61N5/10 ,  A61B5/00 ,  A61N7/02 ,  A61B34/10 ,  A61B6/12 ,  A61B6/03 ,  A61B6/00

CPC classification number: A61N5/1049 ,  A61B5/489 ,  A61B34/10 ,  A61M37/0092 ,  A61N5/103 ,  A61N5/1039 ,  A61N5/1048 ,  A61N5/1064 ,  A61N7/02 ,  A61B5/4836 ,  A61B6/03 ,  A61B6/12 ,  A61B6/504 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058 ,  A61N2005/1061 ,  A61N2005/1087 ,  A61N2005/1092 ,  A61N2005/1098 ,  A61N2007/0004 ,  A61N2007/0039 ,  A61N2007/0052 ,  A61N2007/0082 ,  A61N2007/027

Abstract: Various approaches for computationally generating a protocol for treatment of one or more target BBB regions within a tissue region of interest using a source of focused ultrasound include specifying (i) settings of sonication parameters for applying one or more sequence of sonications to the target BBB region using the source of focused ultrasound and (ii) a characteristic of microbubbles selected to be administered into the target BBB region; electronically simulating treatment in accordance with the protocol at least in part by computationally executing the sequence(s) of sonications and computationally administering the microbubbles having the characteristic; and computationally predicting a tissue disruption effect of the target BBB region resulting from the treatment.

公开(公告)号：US11819709B2

公开(公告)日：2023-11-21

申请号：US18166393

申请日：2023-02-08

Applicant: Videra Surgical Inc.

Inventor： Alex Vayser ,  Sunny Mitchell ,  Henry Jay Lee ,  Joseph Guido

IPC: A61N5/10 ,  A61B90/00 ,  G06T7/00 ,  A61B17/00

CPC classification number: A61N5/1007 ,  A61N5/1049 ,  G06T7/0012 ,  A61B2017/00004 ,  A61B2090/3908 ,  A61B2090/3966 ,  A61B2090/3991 ,  A61N2005/1008 ,  A61N2005/1058 ,  A61N2005/1062 ,  G06T2207/10081 ,  G06T2207/30068 ,  G06T2207/30096 ,  G06T2207/30204

Abstract: A method and apparatus for marking a target with a radiopaque marker is disclosed. The method may include providing a radiopaque filament and inserting at least portion of the radiopaque filament into tissue. The filament may extend continuously and at last partially around a perimeter of the target so that the filament is disposed in a plurality of surgical planes to demarcate the target with the radiopaque maker.

公开(公告)号：US11813114B2

公开(公告)日：2023-11-14

申请号：US15898495

申请日：2018-02-17

Applicant: Elekta LTD.

Inventor： Francois Marcil

IPC: A61B8/00 ,  A61B90/57 ,  A61N5/10 ,  A61B90/50 ,  A61B90/00

CPC classification number: A61B8/4209 ,  A61B8/40 ,  A61B90/50 ,  A61B90/57 ,  A61N5/1039 ,  A61N5/1049 ,  A61B2090/0808 ,  A61B2090/376 ,  A61B2090/378 ,  A61N2005/1058 ,  A61N2005/1097

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on an overlay on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

公开(公告)号：US11648418B2

公开(公告)日：2023-05-16

申请号：US16016272

申请日：2018-06-22

Applicant: RefleXion Medical, Inc.

Inventor： Michael Kirk Owens ,  Rostem Bassalow ,  Peter Demetri Olcott ,  Yevgen Voronenko ,  David Quentin Larkin ,  Samuel Mazin

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1039 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1067 ,  A61N5/1068 ,  A61N5/1036 ,  A61N5/1037 ,  A61N5/1038 ,  A61N5/1045 ,  A61N2005/1034 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058

Abstract: Disclosed herein are systems and methods for adapting and/or updating radiotherapy treatment plans based on biological and/or physiological data and/or anatomical data extracted or calculated from imaging data acquired in real-time (e.g., during a treatment session). Functional imaging data acquired at the time of radiation treatment is used to modify a treatment plan and/or dose delivery instructions to provide a prescribed dose distribution to patient target regions. Also disclosed herein are methods for evaluating treatment plans based on imaging data acquired in real-time.

公开(公告)号：US20190175940A1

公开(公告)日：2019-06-13

申请号：US15836474

申请日：2017-12-08

Applicant: Elekta, Inc.

Inventor： Sami Hissoiny ,  Michel Moreau

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1037 ,  A61N5/1038 ,  A61N5/1039 ,  A61N5/1064 ,  A61N2005/1034 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058 ,  A61N2005/1061

Abstract: Radiation treatment planning and administration can include a Monte Carlo computer simulation tool to simulate photo-generated electrons in tissue. In the simulation, electrons that have left tissue voxels and entered air voxels can be evaluated to identify electrons that are circling along a spiraling trajectory in the air voxels. After at least one full spiraling circumference or other specified distance has been traversed using a detailed electron transport model, a simpler linear ballistic motion model can be instituted. This speeds simulation while accurately accounting for spiraling electrons that re-enter tissue voxels.

公开(公告)号：US20180185671A1

公开(公告)日：2018-07-05

申请号：US15398683

申请日：2017-01-04

Applicant: Varian Medical Systems International AG

Inventor： Reto W. FILIBERTI ,  Stefan G. SCHEIB ,  Michael HUBER

IPC: A61N5/10 ,  A61B90/00

CPC classification number: A61N5/1049 ,  A61B5/113 ,  A61B5/1135 ,  A61B90/39 ,  A61B2090/3937 ,  A61N5/1065 ,  A61N5/1068 ,  A61N5/1069 ,  A61N5/1081 ,  A61N2005/1052 ,  A61N2005/1055 ,  A61N2005/1058 ,  A61N2005/1059 ,  A61N2005/1061

Abstract: An apparatus for assisting a selection of motion management technique for use with a treatment machine having an energy source, comprises: one or more input for obtaining motion trace of a target to be treated, and/or for obtaining motion data of a fiducial; and a motion management processor configured to determine motion management data based at least in part on at least a portion of the motion trace of the target and/or at least a portion of the motion data of the fiducial, wherein the motion management data indicates desirability and/or undesirability of one or more motion management option(s); wherein the motion management processor is also configured to output the motion management data for assisting the selection of the motion management technique for use with the treatment machine.

公开(公告)号：US20170333002A1

公开(公告)日：2017-11-23

申请号：US15588978

申请日：2017-05-08

Applicant: Toshiba Medical Systems Corporation

Inventor： Satoru OHISHI ,  Takayuki KUWAHARA

IPC: A61B8/00 ,  A61B8/08 ,  A61N5/10

CPC classification number: A61B8/4263 ,  A61B6/032 ,  A61B8/085 ,  A61B8/483 ,  A61B8/488 ,  A61N5/103 ,  A61N5/1049 ,  A61N2005/1058

Abstract: A support apparatus comprises processing circuitry. The processing circuitry is configured to calculate, based on an irradiation plan with radiation on a target site of a subject, a recommendation degree of disposition of an ultrasonic probe configured to scan the target site at irradiation with the radiation, for each position in the subject. And the processing circuitry is configured to notify an operator of the recommendation degree in association with a position in the subject.

公开(公告)号：US09743912B2

公开(公告)日：2017-08-29

申请号：US14068990

申请日：2013-10-31

Applicant: QUEEN'S UNIVERSITY AT KINGSTON

Inventor： Gabor Fichtinger ,  Purang Abolmaesumi ,  Clif E. Burdette ,  Thomas Kuiran Chen ,  Andras Lasso ,  Tamas Heffter

IPC: A61B8/00 ,  A61B8/08 ,  A61N5/10 ,  A61B8/12 ,  A61B17/00

CPC classification number: A61B8/587 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/4209 ,  A61B8/4263 ,  A61B8/4281 ,  A61B2017/00274 ,  A61N5/1007 ,  A61N5/1027 ,  A61N2005/1058

Abstract: An ultrasound calibration phantom comprises a portion including at least one fiducial structure having a selected geometric arrangement; a portion adapted for mechanical coupling of the ultrasound calibration phantom to a transrectal ultrasound (TRUS) stepper; and a guide for at least one surgical instrument, the guide being mechanically coupled to the fiducial structure and/or to the TRUS stepper at a selected pose relative to the fiducial structure. A calibration method uses the calibration phantom and provides automatic, intraoperative calibration of ultrasound imaging systems. The invention is useful in ultrasound-guided clinical procedures.