公开(公告)号：US11959911B2

公开(公告)日：2024-04-16

申请号：US17561823

申请日：2021-12-24

申请人： CHENGDU SHEN MINDRAY MEDICAL ELECTRONICS TECHNOLOGY RESEARCH INSTITUTE CO., LTD. ,  SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.

发明人： Wenjun Tong ,  Yijie Yang ,  Huaming Xu ,  Xing Shi

IPC分类号： G01N33/50 ,  G01N1/18 ,  G01N1/38 ,  G01N15/01 ,  G01N15/10 ,  G01N15/14 ,  G01N33/72 ,  G01N35/00 ,  G01N35/10 ,  G01N15/04 ,  G01N15/05

CPC分类号： G01N33/5094 ,  G01N1/18 ,  G01N1/38 ,  G01N15/10 ,  G01N15/14 ,  G01N33/721 ,  G01N33/726 ,  G01N35/00871 ,  G01N35/1097 ,  G01N2015/011 ,  G01N2015/016 ,  G01N2015/055 ,  G01N2015/1006 ,  G01N2015/1024 ,  G01N15/1459 ,  G01N2015/1486 ,  G01N35/1095 ,  G01N2333/805

摘要： The present disclosure provided a blood cell analyzer, a control device and a blood analysis method thereof. In the method, a first reagent is mixed with a sample to obtain a first testing sample, and then a second reagent is mixed with the first testing sample for a further reaction to get a second testing sample for basophil classification and/or HGB measurement. A blood sample may be tested in one reaction cell through time-division multiplexing technology to obtain four groups leukocytes classification result and HGB result by single detection channel. Thus, the structure of the analyzer may be greatly simplified on the premise of guaranteeing the performance of the analyzer, the size and cost of the analyzer may reduce and a performance-price ratio of the analyzer may increase.

公开(公告)号：US11946034B2

公开(公告)日：2024-04-02

申请号：US16932957

申请日：2020-07-20

申请人： NIHON KOHDEN CORPORATION

发明人： Hodaka Makino ,  Hirotsugu Kubo

IPC分类号： C12M1/32 ,  C12M1/12 ,  G01N1/18 ,  G01N1/26 ,  G01N1/10 ,  G01N1/20

CPC分类号： C12M37/00 ,  C12M33/06 ,  G01N1/18 ,  G01N1/26 ,  G01N2001/1056 ,  G01N2001/205

摘要： A sterile sampling apparatus includes a first to seventh flow paths, a sampling section, a first and second pumps, and a first to sixth opening/closing mechanism. The sampling section is disposed in the seventh flow path. The first pump is disposed in the sixth flow path. The second pump is disposed in the seventh flow path. The second flow path includes a first opening/closing mechanism. The third flow path includes a second opening/closing mechanism. The fourth flow path includes a third opening/closing mechanism. The first flow path includes a fourth opening/closing mechanism. The sixth flow path includes a fifth opening/closing mechanism. The seventh flow path includes a sixth opening/closing mechanism. The rate of the second pump is higher than that of the first pump.

公开(公告)号：US11724255B2

公开(公告)日：2023-08-15

申请号：US16792175

申请日：2020-02-14

申请人： Marshall Venture Partners LLC

发明人： Alan R Loudermilk ,  Herbert Hunt Allred ,  Kevin Fuller ,  Wayde J Altendorf

IPC分类号： B01L3/00 ,  G01N1/18 ,  G01N1/28 ,  A61B10/00 ,  G01N1/02

CPC分类号： B01L3/5023 ,  A61B10/0051 ,  B01L3/5025 ,  B01L3/5029 ,  G01N1/18 ,  B01L2200/141 ,  B01L2300/042 ,  B01L2300/0825 ,  G01N2001/028

摘要： A fluid sample testing apparatus has a housing with a test chamber and first and second fluid collector tubes and first and second fluid collectors in fluid communication with the test chamber. A sample holding container is in fluid communication with the second fluid collector tube. The first fluid collector is inserted into the first fluid collector tube and pressure is generated to release fluid from the first fluid collector into the test chamber, and air passes outside of the apparatus from the test chamber via an opening from the test chamber into the first fluid collector tube. The second fluid collector is inserted into the second fluid collector tube concurrently and pressure is generated to release fluid from the second fluid collector into the sample holding container, and air passes outside of the apparatus from the second fluid collector tube.

公开(公告)号：US11692960B2

公开(公告)日：2023-07-04

申请号：US16615549

申请日：2018-05-24

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

发明人： Eric Gouze ,  Frederic Bottausci ,  Pascal Mailley ,  Olivier Fuchs

IPC分类号： G01N27/27 ,  G01N1/18 ,  G01N27/07 ,  G01N27/30 ,  G05D23/24 ,  G01N27/28

CPC分类号： G01N27/27 ,  G01N1/18 ,  G01N27/07 ,  G01N27/283 ,  G01N27/301 ,  G05D23/24

摘要： An electrochemical measurement cartridge includes a container including a first analysis chamber for receiving a fluid to be analyzed and a second calibration chamber for receiving a calibration fluid; an electrochemical measurement sensor including at least one work electrode and one reference electrode; a container supporting the sensor and a cover arranged mobile relative to one another to confer on the cartridge at least two separate operating configurations, a first configuration in which the sensor is communicating with the first analysis chamber and a second configuration in which the sensor is communicating with the second calibration chamber; sealing between the chambers of the container and the cover; and a drive member for providing a relative movement of the container relative to the cover.

公开(公告)号：US11614383B2

公开(公告)日：2023-03-28

申请号：US15733016

申请日：2018-08-31

申请人： MINEX CRC LTD

发明人： Fredrick Allan Blaine ,  Benjamin Graham Van Der Hoek

IPC分类号： G01N1/18 ,  G01N1/20

摘要： The invention relates to a sample collection system for collecting sub-samples from a material stream, the system including a valve arrangement and a static cone splitter, and wherein the valve arrangement is arranged to enable operation of the static cone splitter to collect a non-biased sample of the material stream fed to the static cone splitter under first and second operational conditions, the first operational condition requiring the material stream to be at substantially atmospheric pressure and flowing at a minimum functional flow rate, and the second operational condition requiring the material stream to be pressurised above atmospheric pressure and at a flow rate higher than the minimum functional flow rate. The invention also relates to a static cone splitter for use with the system, together with a cone member for use with the static cone splitter.

公开(公告)号：US20220364960A1

公开(公告)日：2022-11-17

申请号：US17744318

申请日：2022-05-13

申请人： Clarapath, Inc.

发明人： Weston Smith ,  Robert Shusko ,  Partha P. Mitra ,  Baris Yagci

IPC分类号： G01N1/06 ,  G01N1/14 ,  G01N1/18

摘要： Provided here are systems and methods for microtomy, including a microtome and a transfer tape system. The microtome can be used for sectioning a tissue section from a tissue block. The transfer tape system can include a transfer tape configured to adhere to a front face of the tissue block and collect one or more tissue sections sectioned by the microtome and to transfer the one or more tissue sections to one or more slides; and at least one tension device for controlling tension and an angle of the transfer tape relative the tissue block or the one or more slides. The at least one tension device can be configured to maintain the transfer tape at a predetermined tension or maintain the transfer tape at a predetermined angle relative to the tissue block or the one or more slides.

公开(公告)号：US11408903B2

公开(公告)日：2022-08-09

申请号：US17008561

申请日：2020-08-31

申请人： University of Washington

发明人： Daniel T. Chiu ,  Bryant S. Fujimoto ,  Jason E. Kreutz

IPC分类号： G01N1/18 ,  G01N35/10 ,  G01N21/64 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N15/14 ,  B01L3/00 ,  B01L7/00 ,  B01L9/00 ,  C12Q1/686 ,  G01N15/10

摘要： Systems, methods, and devices for discretizing and analyzing fluidic samples are provided. In one aspect, a microfluidic array for discretizing a fluidic sample comprises one or more flow channels and a plurality of fluidic compartments in fluidic communication with the one or more flow channels. In another aspect, a system for discretizing and analyzing fluidic samples comprises a rotor assembly shaped to receive a microfluidic device.

公开(公告)号：US20220117588A1

公开(公告)日：2022-04-21

申请号：US17421296

申请日：2020-01-10

申请人： CONFIRM BIOSCIENCES, INC.

发明人： Serhat Pala

IPC分类号： A61B10/00 ,  B01L3/00 ,  G01N1/18 ,  G01N33/543

摘要： A multi-chamber saliva-collection device is configured to segregate a saliva sample into at least two aliquots, each of the at least two aliquots being contained within a distinct chamber of the multi-chamber device, wherein the multi-chamber device is useful for performing an instant analyte test and a subsequent DNA confirmation to validate the identity of the tested individual. Related methods for using the device to obtain each of: an analyte test result, and a DNA confirmation of the identity of the individual from which the tested saliva sample, are also disclosed.

公开(公告)号：US20210396731A1

公开(公告)日：2021-12-23

申请号：US16907565

申请日：2020-06-22

申请人： Saudi Arabian Oil Company

发明人： Elaf A. Ahmed ,  Sebastien A. Duval ,  Simone Less ,  Ali S. Aldossary

IPC分类号： G01N33/24 ,  G01N1/18 ,  G01N1/20 ,  G01N1/40 ,  G01N27/22

摘要： To measure water content of liquid hydrocarbon using dried liquid hydrocarbon solvent, a liquid hydrocarbon sample is received from a flowline carrying the liquid hydrocarbon. The liquid hydrocarbon sample includes liquid hydrocarbon and liquid water at a concentration greater than a water saturation level. The liquid hydrocarbon sample is split into a first portion and a remainder portion. The first portion is dried to remove liquid water in the first portion. The remainder portion is mixed with the dried first portion causing the concentration of liquid water in a mixture of the remainder portion and the dried first portion to be below the water saturation level. After mixing the remainder portion with the dried first portion, a water content in the liquid hydrocarbon sample is determined.

公开(公告)号：US11099203B2

公开(公告)日：2021-08-24

申请号：US16658835

申请日：2019-10-21

申请人： BECTON, DICKINSON AND COMPANY

发明人： Stephen LaChance ,  Alyssa Shedlosky ,  Alexander Clark ,  Redeat Girma Alemu ,  Craig Bark ,  Steven Charles Rotundo ,  Michael T. Vansickler

IPC分类号： B01L3/00 ,  B01L3/02 ,  G01N1/18 ,  G01N35/10 ,  G01N1/14

摘要： Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.