公开(公告)号：US20230287218A1

公开(公告)日：2023-09-14

申请号：US18013406

申请日：2021-06-03

申请人： DIC Corporation

发明人： Keisuke Sakamoto ,  Yuji Tamura ,  Kentaro Oishi ,  Yuta Hidaka ,  Takeshi Yamada ,  Ryousuke Asami ,  Kengo Yasui ,  Mayumi Tokuoka ,  Katsunori Shimada

IPC分类号： C09B47/10 ,  C09B67/20 ,  C09B67/50

CPC分类号： C09B47/10 ,  C09B67/006 ,  C09B67/0026

摘要： The halogenated zinc phthalocyanine pigment is for use as a green pigment for color filters and capable of achieving high brightness. In the halogenated zinc phthalocyanine pigment, when a coating film containing 1.00 part by mass of the pigment, 0.95 parts by mass of a benzyl methacrylate-methacrylic acid copolymer, and 0.30 parts by mass of a dimethylaminoethyl methacrylate copolymer is heated at 230° C. for one hour to form an evaluation coating film having a thickness of 4 μm, an average scattering intensity at scattering angles 2θ in a range of 17° to 21° is determined from a two-dimensional scattering image obtained by GI-WAXS measurement of the evaluation coating film, and a normalized average scattering intensity is determined such that the average scattering intensity at an azimuth of 45° is 1, the normalized average scattering intensity at azimuths of 5° to 89° is 0.70 to 1.15.

公开(公告)号：US11753525B2

公开(公告)日：2023-09-12

申请号：US17708949

申请日：2022-03-30

申请人： E. & J. Gallo Winery

发明人： Joseph Rossi ,  Sundeep Kattamuri

IPC分类号： C08K5/3417 ,  A23L5/42 ,  A23L5/44 ,  A23L5/46 ,  C08K5/132 ,  C08K5/1545 ,  C09B61/00 ,  C12P7/06 ,  B01D1/06 ,  B01D3/00 ,  B01D9/00 ,  B01D11/04 ,  B01D15/08 ,  B01D61/14 ,  B01D61/58 ,  B01D63/10 ,  B01D71/68

CPC分类号： C08K5/3417 ,  A23L5/42 ,  A23L5/44 ,  A23L5/46 ,  B01D1/065 ,  B01D3/001 ,  B01D9/0031 ,  B01D11/0403 ,  B01D11/0492 ,  B01D15/08 ,  B01D61/145 ,  B01D61/58 ,  B01D63/10 ,  B01D71/68 ,  C08K5/132 ,  C08K5/1545 ,  C09B61/00 ,  C12P7/06 ,  A23V2002/00 ,  B01D2315/16 ,  B01D2325/20 ,  Y02E50/10

摘要： A crystalline pigment or colorant composition having high color intensity and/or low sugar content, and methods and processes of preparation. The composition may comprise purified fruit and/or vegetable color juices.

公开(公告)号：US20230279231A1

公开(公告)日：2023-09-07

申请号：US18197560

申请日：2023-05-15

申请人： The General Hospital Corporation ,  Northeastern University

发明人： Hak Soo Choi ,  Jonghan Kim ,  Georges El Fakhri

IPC分类号： C09B23/01 ,  C09B69/10

CPC分类号： C09B23/0066 ,  C09B23/0025 ,  C09B23/0033 ,  C09B23/0041 ,  C09B69/105

摘要： Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided.

公开(公告)号：US11751471B2

公开(公告)日：2023-09-05

申请号：US17669798

申请日：2022-02-11

申请人： Crius Technology Group, Inc.

发明人： Phillip Bogdanovich

IPC分类号： H04B3/00 ,  H04L25/00 ,  H10K85/60 ,  H04W4/80 ,  H04L41/0833 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/00 ,  C09B69/00 ,  C09K11/06 ,  H04B3/56 ,  H04L12/28 ,  H04L43/00 ,  H05B47/18 ,  H05B47/19 ,  H05B47/185 ,  H05B47/115 ,  H05B47/105 ,  H04B3/54 ,  H04L12/40 ,  H04L43/08 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18

CPC分类号： H10K85/633 ,  C07C209/60 ,  C07C211/61 ,  C07C217/80 ,  C07D209/86 ,  C07D209/94 ,  C07D213/06 ,  C07D213/16 ,  C07D219/02 ,  C07D221/08 ,  C07D223/26 ,  C07D265/38 ,  C07D279/22 ,  C07D307/91 ,  C07D307/93 ,  C07D311/80 ,  C07D333/76 ,  C07D405/04 ,  C07D405/12 ,  C07D407/12 ,  C07D471/06 ,  C07D487/04 ,  C09B19/00 ,  C09B21/00 ,  C09B57/008 ,  C09B69/008 ,  C09K11/06 ,  H04B3/54 ,  H04B3/56 ,  H04L12/2816 ,  H04L12/40 ,  H04L41/0833 ,  H04L43/00 ,  H04W4/80 ,  H05B47/105 ,  H05B47/115 ,  H05B47/18 ,  H05B47/185 ,  H05B47/19 ,  H10K85/636 ,  H10K85/6572 ,  H10K85/6574 ,  H10K85/6576 ,  C07C2601/14 ,  C07C2603/18 ,  C07C2603/26 ,  C07C2603/52 ,  C07C2603/54 ,  C07C2603/94 ,  C07C2603/97 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1029 ,  C09K2211/1088 ,  C09K2211/1092 ,  H04L43/08 ,  H04L2012/2843 ,  H05B47/175 ,  H10K50/11 ,  H10K50/15 ,  H10K50/17 ,  H10K50/18 ,  H10K85/615 ,  H10K85/626 ,  Y02E10/549

摘要： Methods, systems, and apparatus for monitoring and controlling electronic devices using wired and wireless protocols are disclosed. The systems and apparatus may monitor their environment for signals from electronic devices. The systems and apparatus may take and disambiguate the signals that are received from the devices in their environment to identify the devices and associate control signals with the devices. The systems and apparatus may use communication means to send control signals to the identified electronic devices. Multiple apparatuses or systems may be connected together into networks, including mesh networks, to make for a more robust architecture.

公开(公告)号：US20230272221A1

公开(公告)日：2023-08-31

申请号：US18111220

申请日：2023-02-17

申请人： Ultima Genomics, Inc.

发明人： Linda G. LEE ,  Steven MENCHEN

IPC分类号： C09B49/04 ,  C09B11/24 ,  C07H19/20

CPC分类号： C09B49/04 ,  C09B11/24 ,  C07H19/20

摘要： The present disclosure provides labeling reagents for labeling substrates such as nucleotides, proteins, antibodies, lipids, and cells. The labeling reagents provided herein may comprise fluorescent labels and semi-rigid linkers. Methods for nucleic acid sequencing using materials comprising such labeling reagents are also provided herein. Also provided are labeling reagents for labeling multiple substrates simultaneously using energy transfer.

公开(公告)号：US11738096B2

公开(公告)日：2023-08-29

申请号：US16334734

申请日：2017-09-22

申请人： University of Rhode Island Board of Trustees ,  Yale University

发明人： Yana K. Reshetnyak ,  Oleg A. Andreev ,  Donald M. Engelman

IPC分类号： A61K49/00 ,  C07K19/00 ,  C07K14/00 ,  A61B5/00 ,  G01N33/58 ,  A61K49/22 ,  C09B69/10 ,  C09K11/06 ,  A61K49/04

CPC分类号： A61K49/0056 ,  A61B5/0082 ,  A61K49/0034 ,  A61K49/04 ,  A61K49/221 ,  A61K49/227 ,  C07K14/001 ,  C07K19/00 ,  C09B69/107 ,  C09K11/06 ,  G01N33/582 ,  A61B5/0071 ,  C09K2211/1466

摘要： The present subject matter provides compounds, compositions, and methods for identifying, monitoring, treating, and removing diseased tissue. Compounds, compositions, and methods for identifying, monitoring, and detecting circulating fluids such as blood are also provided.

公开(公告)号：US20230266667A1

公开(公告)日：2023-08-24

申请号：US18012325

申请日：2021-06-10

申请人： AGFA Offset BV

发明人： Thomas Billiet ,  Kristof Heylen ,  Faïma Lazreg ,  Johan Loccufier

IPC分类号： G03F7/004 ,  B41C1/10 ,  G03F7/038 ,  C09B23/10

CPC分类号： G03F7/0045 ,  B41C1/1016 ,  G03F7/038 ,  C09B23/107 ,  B41C2201/12 ,  B41C2201/02 ,  B41C2210/04 ,  B41C2210/08 ,  B41C2210/22

摘要： A lithographic printing plate precursor is disclosed including on a support a coating comprising (i) a photopolymerisable layer including a polymerisable compound, a first infrared absorbing dye including at least one electron withdrawing substituent and a photoinitiator; and (ii) a top layer provided above the photopolymerisable layer which includes a second infrared absorbing compound which includes a thermocleavable group which transforms into a group which is a stronger electron-donor upon exposure to heat and/or IR radiation, and is capable of forming a print-out image upon exposure to heat and/or IR radiation.

公开(公告)号：US11732138B2

公开(公告)日：2023-08-22

申请号：US17955087

申请日：2022-09-28

申请人： BECTON, DICKINSON AND COMPANY

发明人： Yongchao Liang ,  Jonathan Hollinger ,  Brian Wall ,  David Moureau ,  Lucy Zhao ,  Glenn P. Bartholomew

IPC分类号： C09B69/10 ,  C08G61/10 ,  C08G61/12 ,  C09B69/00 ,  G01N33/58 ,  G01N33/542 ,  G01N33/533

CPC分类号： C09B69/109 ,  C08G61/10 ,  C08G61/12 ,  C09B69/00 ,  C09B69/101 ,  C09B69/102 ,  G01N33/582 ,  C08G2261/135 ,  C08G2261/143 ,  C08G2261/145 ,  C08G2261/1424 ,  C08G2261/1452 ,  C08G2261/1644 ,  C08G2261/312 ,  C08G2261/334 ,  C08G2261/344 ,  C08G2261/522 ,  C08G2261/90 ,  G01N33/533 ,  G01N33/542

摘要： Water solvated polymeric dyes having a deep ultraviolet excitation spectrum are provided. The subject polymeric dyes include a light harvesting multichromophore having conjugation-modifying repeat units incorporated into the polymer backbone to provide segments of π-conjugated co-monomers having limited π-conjugation between segments. Polymeric tandem dyes are also provided that further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are labelled specific binding members that include the subject water solvated polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.

公开(公告)号：US20230255929A1

公开(公告)日：2023-08-17

申请号：US18138351

申请日：2023-04-24

申请人： SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH

发明人： Mark G. Frattini ,  Hakim Djaballah ,  Thomas J. Kelly

IPC分类号： A61K31/365 ,  A61K31/122 ,  C09B13/02 ,  C09B61/00 ,  C12Q1/6886 ,  A61K31/352 ,  A61N5/10 ,  C07D493/08 ,  C07D493/18 ,  A61K9/00

CPC分类号： A61K31/365 ,  A61K31/122 ,  C09B13/02 ,  C09B61/00 ,  C12Q1/6886 ,  A61K31/352 ,  A61N5/10 ,  C07D493/08 ,  C07D493/18 ,  A61K9/0019 ,  C12Q2600/106 ,  C12Q2600/156

摘要： The invention provides compounds, methods, pharmaceutical compositions, and kits for the treatment of proliferative disorders such as cancer. In one aspect, the methods comprise compounds that inhibit the activity of protein kinases, such as cell division cycle (Cdc) kinase. In another aspect, the methods comprise compounds that inhibit Cdc7 and/or Dbf4 activity. In another aspect, the methods comprise compounds that exhibit anti-proliferative properties useful in treating diseases such as cancer. Compounds useful for any of the methods include compounds of the Formula (A) or (B):




or pharmaceutically acceptable salts thereof. Exemplary compounds of Formula (A) or (B) include granaticin A, granaticin B, dihydrogranaticin A, dihydrogranaticin B, medermycin, and actinorhodin.

公开(公告)号：US11723389B2

公开(公告)日：2023-08-15

申请号：US16766041

申请日：2018-11-06

申请人： DIC Corporation

发明人： Hiromasa Nakamura ,  Hisayoshi Arai ,  Junichi Itoh ,  Mitsuteru Ishiwara

IPC分类号： A23L5/46 ,  A23L2/58 ,  C09B61/00 ,  C09B67/20

CPC分类号： A23L5/46 ,  A23L2/58 ,  C09B61/00 ,  C09B67/0066 ,  A23V2002/00

摘要： The present invention provides an aqueous pigment-material solution which has excellent thermal stability and less fading particularly even under an acidic condition, a method for producing the same, and a blue-colored beverage. Provided are an aqueous pigment-material solution including a pigment material containing 20 mmol to 200 mmol of polycarboxylic acid having one or more hydroxy groups, in terms of carboxylic acid equivalent, per 1 g of phycocyanin, in which when both the phycocyanin and the polycarboxylic acid are added such that a color value represented by absorbance at 620 nm is 2.5 to 5, an optical density per 1 cm of an optical path length at 800 nm is 0.05 or lower at a hydrogen ion concentration (pH) of 3 or lower, a method for producing the aqueous pigment-material solution, and a blue-colored beverage.