公开(公告)号：US20190033193A1

公开(公告)日：2019-01-31

申请号：US15755782

申请日：2016-08-10

Applicant: CHELSEA TECHNOLOGIES GROUP LTD

Inventor： Kevin OXBOROUGH ,  John ATTRIDGE ,  David ANDREWES

IPC: G01N15/06 ,  G01N33/18 ,  G01N1/38

CPC classification number: G01N15/06 ,  B63J4/002 ,  C02F1/00 ,  C02F1/008 ,  C02F2103/008 ,  C02F2209/001 ,  C02F2209/36 ,  C02F2303/04 ,  G01N1/38 ,  G01N21/6408 ,  G01N21/6486 ,  G01N33/1826 ,  G01N2001/2064 ,  G01N2001/386 ,  G01N2015/0693 ,  G01N2021/635 ,  G01N2021/6419 ,  G01N2021/6478 ,  G01N2021/6482 ,  G01N2201/0627 ,  G01N2201/0631 ,  G01N2201/0638 ,  G01N2201/064 ,  G01N2201/0696 ,  Y02A20/206

Abstract: A ballast water monitoring device and a method for detecting live phytoplankton are disclosed. The device comprises a chamber for receiving a sample, at least one light source to emit light towards the sample, a light detector to receive light from the sample and generate a light signal, and a controller. The controller is configured to control the at least one light source to emit a single pulse of light, calculate the variable fluorescence [Fv] of the sample in response to the pulse of light, at time intervals less than the duration of the pulse of light, compare the calculated variable fluorescence to a predetermined reference limit, and perform an action if the calculated variable fluorescence is greater than the predetermined reference limit.

公开(公告)号：US09913582B2

公开(公告)日：2018-03-13

申请号：US14966824

申请日：2015-12-11

Applicant: SEIKO EPSON CORPORATION

Inventor： Hideto Yamashita ,  Yoshitaka Iijima

IPC: G01N21/55 ,  A61B5/00 ,  A61B5/024 ,  A61B5/1455 ,  G01N21/47 ,  G01N21/49 ,  A61B5/0205

CPC classification number: A61B5/0059 ,  A61B5/02055 ,  A61B5/02427 ,  A61B5/02438 ,  A61B5/02444 ,  A61B5/14552 ,  A61B5/681 ,  A61B5/7278 ,  A61B2562/0219 ,  A61B2562/0238 ,  G01N21/474 ,  G01N21/49 ,  G01N2201/064

Abstract: A biological information detector includes a wristband, a housing, an opening, a light-emitting part, a reflecting part, a light-receiving part, and a protecting part. The opening is defined in a surface of the housing adapted to face a surface of the wrist of the user. The light-emitting part is disposed inside the housing and configured to emit green light. The reflecting part is disposed in periphery of the light emitting part, and configured to reflect the light emitted by the light-emitting part, wherein the reflecting part is disposed inside the housing. The light-receiving part is disposed inside the housing, and configured to receive reflected light reflected at a detection site of the wrist of the user. The protecting part is configured to protect the light-emitting part and the reflecting part, and is disposed at the opening of the housing to contact with the detection site.

公开(公告)号：US20170371139A1

公开(公告)日：2017-12-28

申请号：US15539706

申请日：2015-01-05

Applicant: Shimadzu Corporation

Inventor： Atsushi UEDA

IPC: G02B21/04 ,  G01N21/35 ,  G01N21/552 ,  G02B7/18

CPC classification number: G02B21/04 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/552 ,  G01N2201/0636 ,  G01N2201/0638 ,  G01N2201/064 ,  G02B7/1805 ,  G02B21/26

Abstract: An objective optical system includes a convex secondary mirror configured to reflect a measurement light irradiated from an infrared microscope, a concave primary mirror configured to reflect the measurement light reflected by the secondary mirror, a prism to which the measurement light reflected by the primary mirror is irradiated, and a light shielding means provided on an optical path of the measurement light between the primary mirror and the prism to shield a part of the light beam of the measurement light.

公开(公告)号：US20160266111A1

公开(公告)日：2016-09-15

申请号：US15033319

申请日：2014-10-31

Applicant: KONICA MINOLTA, INC.

Inventor： Kosuke NAGAE ,  Hiroshi HIRAYAMA

IPC: G01N33/543 ,  G01N1/14 ,  G01N33/553 ,  G01N21/64

CPC classification number: G01N33/54373 ,  B01L3/5027 ,  B01L2200/16 ,  B01L2300/0636 ,  B01L2300/0654 ,  B01L2300/1816 ,  G01N1/14 ,  G01N21/0332 ,  G01N21/13 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/648 ,  G01N33/553 ,  G01N2021/6439 ,  G01N2201/0231 ,  G01N2201/06113 ,  G01N2201/064

Abstract: This detection device has a holder and a heating unit. The holder holds a detection chip that has the following: a prism that has an incidence surface and a film-formation surface; a metal film formed on said film-formation surface; trapping bodies laid out on the surface of said metal film; and a substrate that is laid out on the surface of the metal film, and together with the metal film, forms a liquid collection section in which a liquid is collected. The heating unit heats at least one of the substrate, the prism, and the metal film either while in contact therewith or without contacting same. Also, the heating unit is positioned so as to avoid the path that excitation light takes from an excitation-light emission unit to the abovementioned incidence surface.

Abstract translation: 该检测装置具有支架和加热单元。 保持器保持具有以下的检测芯片：具有入射表面和成膜表面的棱镜; 形成在所述成膜表面上的金属膜; 在所述金属膜的表面上布置的捕获体; 以及布置在金属膜的表面上的基板，与金属膜一起形成收集液体的液体收集部。 加热单元在与其接触或不与其接触的同时加热基板，棱镜和金属膜中的至少一个。 此外，加热单元被定位成避免激发光从激发光发射单元到上述入射表面的路径。

公开(公告)号：US20160258872A1

公开(公告)日：2016-09-08

申请号：US15028820

申请日：2014-06-25

Applicant: KOREA OCEANIC AND ATMOSPHERIC SYSTEM TECHNOLOGY (KOAST)

Inventor： Hyo Hyuc IM ,  Kyu Young CHOI ,  Deok Whan CHOI

IPC: G01N21/64 ,  G01N33/483

CPC classification number: G01N21/6486 ,  G01N21/6456 ,  G01N33/4833 ,  G01N33/5097 ,  G01N33/5308 ,  G01N2201/061 ,  G01N2201/064

Abstract: A plankton examination apparatus comprises: a sub-pipe in which a transparent pipe unit; a light source unit which radiates only blue-series light; a detection unit which receives light radiated in the direction on the other side outside the transparent pipe unit through the transparent pipe unit from the light source unit and generates an image of the plankton; and a dichroic mirror installed between the transparent pipe unit and the detection unit in such a way as to transmit only red-series light which belongs to the light radiated by the light source unit and passed through the transparent pipe unit and has a wavelength of 620 nm to 780 nm and to deliver the red-series light to the detection unit.

Abstract translation: 浮游生物检查装置包括：副管，其中透明管单元; 仅发射蓝色系列光的光源单元; 检测单元，其从所述光源单元通过所述透明管单元接收在所述透明管单元的外侧的另一侧的方向上照射的光，并生成所述浮游生物的图像; 以及安装在透明管单元和检测单元之间的分色镜，以仅透射属于由光源单元辐射的光并通过透明管单元并具有620的波长的红色系列的光 nm至780nm，并将红色系列光输送到检测单元。

公开(公告)号：US09404869B2

公开(公告)日：2016-08-02

申请号：US14049470

申请日：2013-10-09

Applicant: Howard Hughes Medical Institute

Inventor： Philipp Johannes Keller

IPC: G01N21/64 ,  G01N21/17 ,  A61B5/00

CPC classification number: G01N21/6486 ,  A61B5/0071 ,  A61B2503/42 ,  G01N21/64 ,  G01N33/4833 ,  G01N2021/1736 ,  G01N2201/06193 ,  G01N2201/064 ,  G02B21/0004 ,  G02B21/0048 ,  G02B21/06 ,  G02B21/16 ,  G02B21/361 ,  G02B21/362 ,  G02B21/367 ,  G02B27/1013

Abstract: A live biological specimen is imaged by generating a plurality of light sheets; directing the plurality of light sheets along an illumination axis through the biological specimen such that the light sheets spatially and temporally overlap within the biological specimen along an image plane, and optically interact with the biological specimen within the image plane; and recording, at each of a plurality of views, images of the fluorescence emitted along a detection axis from the biological specimen due to the optical interaction between the light sheets and the biological specimen. The temporal overlap is within a time shift that is less than a resolution time that corresponds to a spatial resolution limit of the microscope.

Abstract translation: 通过生成多个光片对活体生物样本进行成像; 沿着照明轴线引导多个光片通过生物样本，使得光片沿着图像平面在空间和时间上在生物样本内重叠，并与图像平面内的生物样本光学相互作用; 并且在多个视图的每一个处，由于光片和生物样本之间的光学相互作用，沿着检测轴从生物样本记录荧光的图像。 时间重叠在时间偏移之内，其小于对应于显微镜的空间分辨率极限的分辨率时间。

公开(公告)号：US20160120450A1

公开(公告)日：2016-05-05

申请号：US14926174

申请日：2015-10-29

Applicant: Seiko Epson Corporation

Inventor： Kazunori SAKURAI

IPC: A61B5/1455 ,  A61B5/00 ,  G01J3/02

CPC classification number: A61B5/14552 ,  A61B5/6831 ,  A61B5/6833 ,  A61B2560/0406 ,  A61B2562/0233 ,  A61B2562/185 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0259 ,  G01J3/0291 ,  G01J3/26 ,  G01N21/01 ,  G01N21/31 ,  G01N2201/0227 ,  G01N2201/064

Abstract: A biological body inspection apparatus includes a measurement module that acquires an amount of light having a wavelength under measurement contained in light incident on the measurement module and an enclosure that accommodates the measurement module and has a window that transmits light traveling toward the measurement module. An adhesive member is provided on a surface of the enclosure at least in an area thereof that surrounds the window. The adhesive member has a light blocking section that is located in an area outside the window and surrounds the window in a plan view in the direction along the optical axis of the light traveling toward the measurement module and blocks light that belongs to a measurement wavelength region within which at least the wavelength under measurement is present.

Abstract translation: 生物体检查装置包括测量模块，该测量模块获取入射在测量模块上的光所包含的测量波长的光量，以及容纳测量模块的外壳，并且具有透射朝向测量模块传播的光的窗口。 至少在其围绕窗户的区域中，在外壳的表面上设置粘合构件。 所述粘接部件具有遮光部，所述遮光部位于所述窗外部的区域中，并且沿着朝向所述测量模块行进的所述光的光轴方向的俯视图中包围所述窗，并且遮挡属于所述测量波长区域的光 其中至少存在测量波长。

公开(公告)号：US20160003731A1

公开(公告)日：2016-01-07

申请号：US14768680

申请日：2014-02-19

Applicant: ABBOTT POINT OF CARE, INC.

Inventor： Manav Mehta ,  Robert Holt

IPC: G01N21/03 ,  G01N21/59 ,  G01N33/49

CPC classification number: G01N21/0303 ,  B01L3/502715 ,  B01L3/502746 ,  G01N21/59 ,  G01N21/6428 ,  G01N33/49 ,  G01N2021/0307 ,  G01N2021/6482 ,  G01N2035/00158 ,  G01N2201/064

Abstract: A biological fluid sample analysis chamber and a method for analyzing a biological fluid sample is provided. The chamber includes a first chamber panel, a second chamber panel, and a plurality of beads disposed between the first chamber panel and the second chamber panel, which beads are configured to not reflect light incident to the beads in an amount that appreciably interferes with a photometric analysis of the biologic fluid.

Abstract translation: 提供生物流体样品分析室和分析生物流体样品的方法。 腔室包括第一腔室面板，第二腔室面板和设置在第一腔室面板和第二腔室面板之间的多个珠子，所述珠子被配置为不反射入射到珠子的光，其量明显干扰 生物液的光度分析。

公开(公告)号：US20150330901A1

公开(公告)日：2015-11-19

申请号：US14716438

申请日：2015-05-19

Applicant: Lumos Technology Co., Ltd.

Inventor： Chih-Yi Yang

IPC: G01N21/64

CPC classification number: G02B21/06 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2201/062 ,  G01N2201/064 ,  G02B21/16 ,  G02B21/361

Abstract: A fluorescent biological sample operating and monitoring system for restricting the range of movement of a biological sample to facilitate observation. The system includes: a base formed with a predetermined observation position; a shield formed with an operation opening and cooperating with the base to define a light shielding cavity; an infrared illuminating device for illuminating the predetermined observation position; a low-angle excitation light source device including an excitation light source that emits light in a direction oriented toward the predetermined observation position and of a wavelength smaller than that of light emitted by the infrared illuminating device; and an observation display device including an image capturing device having a lens disposed within the shield for capturing an infrared image and oriented toward the predetermined observation position, and an image display.

Abstract translation: 用于限制生物样品的运动范围的荧光生物样品操作和监测系统，以便于观察。 该系统包括：形成有预定观察位置的底座; 形成有操作开口并与基座配合以限定遮光腔的屏蔽件; 用于照亮所述预定观察位置的红外线照明装置; 低角度激发光源装置，其具有：朝向所述规定观察位置的方向发光的激励光源，并且比由所述红外线照明装置发出的光的波长小的波长; 以及观察显示装置，其包括具有设置在所述屏蔽内的用于捕获红外图像并朝向所述预定观察位置定向的所述透镜的图像捕获装置和图像显示器。

公开(公告)号：US20150211986A1

公开(公告)日：2015-07-30

申请号：US14411373

申请日：2012-10-22

Applicant: ZHEJIANG UNIVERSITY

Inventor： Cuifang Kuang ,  Shuai Li ,  Xiang Hao ,  Zhaotai Gu ,  Xu Liu

IPC: G01N21/27 ,  G02B21/00 ,  G01N21/25

CPC classification number: G01N21/27 ,  G01N21/255 ,  G01N21/6458 ,  G01N2201/06113 ,  G01N2201/064 ,  G02B21/002 ,  G02B21/0032 ,  G02B21/0068 ,  G02B27/58

Abstract: This invention discloses a super-resolution microscopy method and device, of which the method comprises the following steps: converting laser beam into linearly polarized light after collimation; linearly polarized light is deflected and phase modulated by a spatial light modulator; the deflected beam is focused, collimated and then converted into circularly polarized light for projection on the sample to collect signal light from various scanning points on the sample, and obtaining the first signal light intensity; switching over modulation function to project linearly polarized light modulated by the second phase modulation on the sample to collect signal light from various scanning points on the sample, and obtaining the second signal light intensity; calculating valid signal light intensity to obtain the super-resolution image. This device features in a simple structure and easy operation, which can obtain a super-resolution beyond diffraction limit at a lower luminous power; it is quick in image formation with the frame frequency over 15 frames when the number of scanning points in each image is 512×512 .

Abstract translation: 本发明公开了一种超分辨率显微镜方法和装置，其方法包括以下步骤：准直后将激光束转换成线偏振光; 线性偏振光被空间光调制器偏转和相位调制; 偏转光束被聚焦，准直，然后转换成圆偏振光，用于投射在样品上，以从样品上的各个扫描点收集信号光，并获得第一信号光强度; 切换调制功能，将样品上的第二相位调制调制的线偏振光投射到样品上的各个扫描点，以获得第二信号光强度; 计算有效信号光强度以获得超分辨率图像。 该器件结构简单，操作方便，可以在较低的发光功率下获得超过衍射极限的超分辨率; 当每个图像中的扫描点数量为512×512时，帧频超过15帧的图像形成速度很快。