公开(公告)号：US10473611B2

公开(公告)日：2019-11-12

申请号：US14886798

申请日：2015-10-19

申请人： ARKRAY, Inc.

发明人： Yosuke Murase

IPC分类号： G01N27/30 ,  H05K1/09 ,  G01N27/40 ,  A61B5/1486 ,  H05K1/02 ,  H05K1/03

摘要： An electrochemical sensor includes a base member, a conductor disposed on the base member, an insulating layer covering the conductor with a portion of the conductor exposed, a silver/silver chloride electrode formed on at least the exposed portion of the conductor, and a water-permeable organic layer covering the silver/silver chloride electrode.

公开(公告)号：US10436738B2

公开(公告)日：2019-10-08

申请号：US15384799

申请日：2016-12-20

申请人： Endress+Hauser Conducta GmbH+Co. KG

发明人： Andreas Löbbert ,  Alexander Hörig

IPC分类号： G01N27/40 ,  B05D3/06 ,  B05D3/14 ,  G01N21/77 ,  G01N21/64

摘要： The present disclosure concerns a membrane for a sensor, such as an opto-chemical or electrochemical sensor, including a polymer layer, for example, one featuring pores or openings, that is permeable to a measuring fluid and/or an analyte contained in the measuring fluid, with a surface designed to be in contact with a measuring fluid, wherein the surface is designed such that, at least in a moist condition of the polymer layer obtained by moistening the surface, a contact angle of a water drop applied to the surface is less than 50°, including less than 30°, and including less than 10°.

公开(公告)号：US10416113B2

公开(公告)日：2019-09-17

申请号：US15505015

申请日：2015-08-20

申请人： Carrier Corporation

发明人： Lei Chen ,  Zhiwei Yang ,  Antonio M. Vincitore ,  Michael L. Perry ,  Warren Clough

IPC分类号： G01N27/40 ,  G01N27/416 ,  G01N27/404 ,  G01N33/00 ,  G01N27/407

摘要： A gas sensor for detecting one or more contaminants in a refrigerant includes a housing having disposed therein a membrane electrode assembly comprising a sensing electrode, a counter electrode, and a solid polymer electrolyte disposed between the sensing electrode and the counter electrode. The sensing electrode comprises nanoparticles of a first catalyst comprising noble metal. The counter electrode comprises nanoparticles of a second catalyst comprising noble metal. The sensing electrode in the sensor has been preconditioned by exposure under a positive voltage bias to a preconditioning gas comprising the contaminant(s) or their precursors or derivatives.

公开(公告)号：US10408785B2

公开(公告)日：2019-09-10

申请号：US15565254

申请日：2016-04-06

申请人： Robert Bosch GmbH

发明人： Michael Fey

IPC分类号： G01N27/40 ,  G01N27/406 ,  G01N27/407 ,  G01N27/417

摘要： A method for determining an internal resistance of a sensor element. The method includes: a) applying a current pulse to the sensor element; the current pulse inducing a charge transfer in the sensor element; the occurrence of the charge transfer causing an increase in the electrical voltage between the first electrode and the second electrode of the sensor element; b) ascertaining a value for the increase in the electrical voltage between the first electrode and the second electrode, step b) being performed at least twice at different points in time during the occurrence of the charge transfer; and a value for increasing the electrical voltage being ascertained therefrom at various points in time; and c) determining the internal resistance of the sensor element from the values for increasing the electrical voltage that are ascertained at different points in time during the occurrence of the charge transfer.

公开(公告)号：US20190246958A1

公开(公告)日：2019-08-15

申请号：US15894255

申请日：2018-02-12

申请人： Giner, Inc.

发明人： Michael Moeller ,  Brian Rasimick

IPC分类号： A61B5/1477 ,  G01N27/403 ,  G01N27/40 ,  A61B5/145 ,  A61B5/00

CPC分类号： A61B5/1477 ,  A61B5/14546 ,  A61B5/4845 ,  A61B2560/0252 ,  A61B2562/125 ,  G01N27/40 ,  G01N27/403

摘要： Waterless electrochemical transdermal alcohol sensor. In one embodiment, the sensor includes a proton exchange membrane imbibed with an imbibing liquid that includes at least one cationic substance that is liquid at room temperature. As examples, the cationic substance may be one or more ionic liquids with an imidazolium, phosphonium, ammonium, pyridinium, pyrrolidinium, or sulfonium backbone structure. The imbibing of the proton exchange membrane with the cationic substance obviates the need for the periodic addition of water to the electrochemical cell. The sensor additionally includes a sensing electrode, which is bonded to one side of the proton exchange membrane, and a counter electrode and a reference electrode, both of which are bonded to the opposite side of the proton exchange membrane. The sensor may be incorporated into a wearable transdermal alcohol sensor device, which, in turn, may be incorporated into a system for detecting transdermal alcohol.

公开(公告)号：US20180328877A1

公开(公告)日：2018-11-15

申请号：US15900639

申请日：2018-02-20

申请人： MEDTRONIC MINIMED, INC.

发明人： Santhisagar Vaddiraju ,  Dennis Slomski ,  Raeann Gifford

IPC分类号： G01N27/327 ,  G01N27/40 ,  C23C14/20 ,  C23C14/34 ,  C23C14/58 ,  A61B5/145 ,  A61B5/1486

CPC分类号： A61B5/1486 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/14865 ,  A61B2562/0209 ,  A61B2562/125 ,  B23K26/36 ,  B41M1/06 ,  B41M1/10 ,  B41M1/12 ,  B41M5/0047 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  C23C14/205 ,  C23C14/34 ,  C23C14/5813 ,  G01N27/3271 ,  G01N27/3272

摘要： Analyte sensors and methods for fabricating analyte sensors are provided. In an exemplary embodiment, a planar flexible analyte sensor includes a flexible base layer and a first electrode formed from a layer of sputtered platinum on the base layer. Also, the analyte sensor includes an insulating dielectric layer over the base layer, wherein the insulating dielectric layer leaves a portion of the first electrode exposed. Further, the analyte sensor includes an electrochemical sensing stack over the exposed portion of the first electrode, including a glucose oxidase layer over the layer of sputtered platinum and a glucose limiting membrane over the glucose oxidase layer.

公开(公告)号：US20180256137A1

公开(公告)日：2018-09-13

申请号：US15769435

申请日：2016-10-23

申请人： Eccrine Systems, Inc.

发明人： Jason Heikenfeld ,  Hector Wong ,  Kevin Plaxco ,  Jacob A. Bertrand

IPC分类号： A61B10/00 ,  G01N33/487 ,  A61B5/145 ,  A61B5/1477 ,  A61B5/00 ,  G01N27/327 ,  G01N27/40

CPC分类号： A61B10/0064 ,  A61B5/14521 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/4266 ,  A61B5/6802 ,  A61B5/6803 ,  A61B5/6804 ,  A61B2562/04 ,  A61B2562/16 ,  G01N27/3276 ,  G01N27/40 ,  G01N33/48707 ,  G01N33/50

摘要： Embodiments of the disclosed invention provide devices and methods for buffering fluid samples to enable accurate concentration measurements of analytes by salinity-sensitive or pH-sensitive sensors. The buffering capabilities of the device include the ability to control the salinity and pH of a fluid sample, specifically, through the management of solutes such as salts, H+, other ions, and other solutes, that are found in sweat, biofluids, or other fluids. The purpose of such control is to enhance particular fluid sensing device applications by improving detectability of the targeted analyte, or improving performance of analyte sensors. Some embodiments also include components to enable sample concentration to enhance the measurement of low-concentration solutes found in the fluid.

公开(公告)号：US20180092562A1

公开(公告)日：2018-04-05

申请号：US15282926

申请日：2016-09-30

申请人： Lev Cherkashin ,  John Carroll Gordon

发明人： Lev Cherkashin ,  John Carroll Gordon

IPC分类号： A61B5/0402 ,  G01N27/04 ,  G01N27/327 ,  G01N27/40 ,  A61B5/0408 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/0496

CPC分类号： A61B5/04026 ,  A61B5/0408 ,  A61B5/0478 ,  A61B5/0492 ,  A61B5/0496 ,  A61B2562/0209 ,  G01N27/04 ,  G01N27/327 ,  G01N27/40

摘要： In various embodiments, methods and systems, of an ionic varistor system is provided. The ionic varistor system includes an electrolyte-membrane assembly having a liquid electrolyte that is enclosed in a solid electrolyte membrane. The ionic varistor system further includes conductive contacts operably coupled to the electrolyte-membrane assembly. The electrolytic-membrane assembly is operably coupled to an electrical potential surface. As the ionic concentration in the electrical potential surface is increased or decreased, some ions diffuse through the solid electrolyte membrane, causing the ions to mix with the liquid electrolyte to achieve an electrostatic equilibrium state that is thermally and mechanically stable. The liquid electrolyte and the diffused ions create an encapsulated ion channel in the electrolyte-membrane assembly. The electrical conductivity of the encapsulated ion channel increases as the ion concentration increases such that the complete electrolyte-membrane assembly produces electrical resistance. The ion concentration is measured as indicator of electrical potential of the electrical potential surface.

公开(公告)号：US20180023205A1

公开(公告)日：2018-01-25

申请号：US15597126

申请日：2017-05-16

申请人： FCET, INC. ,  UT-Battelle, LLC

发明人： Leonid V. Budaragin ,  Mark A. Deininger ,  Michael M. Pozvonkov ,  D. Morgan Spears, II ,  Paul D. Fisher ,  Arvid E. Pasto

IPC分类号： C25B13/04 ,  C25B9/00 ,  C25B9/08 ,  G01N27/407 ,  G01N27/28 ,  G01N27/40 ,  H01M8/00 ,  H01B1/12 ,  C25B5/00 ,  C25B9/10

CPC分类号： C25B13/04 ,  C25B9/08 ,  C25B9/10 ,  G01N27/40 ,  G01N27/4073 ,  H01B1/122 ,  H01M8/004 ,  H01M8/0271 ,  H01M8/1006 ,  H01M8/1007 ,  H01M8/1016 ,  H01M8/1246 ,  H01M8/1253 ,  H01M8/126 ,  H01M8/243 ,  H01M2008/1293 ,  H01M2300/0071 ,  H01M2300/0074 ,  H01M2300/0077 ,  H01M2300/0091 ,  Y02E60/525 ,  Y02P70/56

摘要： Methods for forming a metal oxide electrolyte improve ionic conductivity. Some of those methods involve applying a first metal compound to a substrate, converting that metal compound to a metal oxide, applying a different metal compound to the metal oxide, and converting the different metal compound to form a second metal oxide. Electrolytes so formed can be used in solid oxide fuel cells, electrolyzers, and sensors, among other applications.

公开(公告)号：US20170370948A1

公开(公告)日：2017-12-28

申请号：US15543151

申请日：2015-07-28

申请人： FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ICIQ) ,  INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS ,  UNIVERSITAT ROVIRA I VIRGILI

发明人： Louis ADRIAENSSENS ,  Pau BALLESTER ,  Francisco Javier ANDRADE ,  Pascal BLONDEAU ,  Francesc Xavier RIUS ,  Tomas De Aquino GUINOVART PAVON ,  Daniel HERNANDEZ ALONSO

IPC分类号： G01N33/70 ,  C08K5/55 ,  C08K5/5373 ,  C07D491/22 ,  B01J39/16 ,  C08J5/22 ,  C07F9/6571 ,  G01N27/40 ,  C08K5/32

CPC分类号： G01N33/70 ,  B01J39/16 ,  C07D403/14 ,  C07D487/22 ,  C07D491/22 ,  C07F9/657181 ,  C08J5/22 ,  C08J2327/06 ,  C08K5/32 ,  C08K5/5373 ,  C08K5/55 ,  G01N27/40

摘要： Compounds are of the formula (Ia), (Ib), (Ic), or are stereoisomers thereof, wherein: R1 is hydrogen, (C1-C20)alkyl; (C3-C20)alkenyl; (C3 C20)alkynyl; (C1-C6)alkyl-O—; (C3-C20)cycloalkyl; (C1 C20)haloalkyl; (C6-C20)aryl optionally substituted; (C6-C20)heteroaryl optionally substituted; R2 and R2′ are hydrogen; (C1-C20)alkyl; (C1-C6)alkyl-O—; (C1-C6)haloalkyl; halogen;cyano; and nitro; Z1 to Z4 are diradicals of formula (III) wherein Al and A2 are O—or —NR3-, wherein R3 is selected from the group consisting of hydrogen and (C1-C20)alkyl; and G is (C1-C6)alkyl; —P(═S)R5-; —P(═O)R4; P(═O)(OR4)-; —P(═O)(NR6R7)-; —S(=0)2-; S(═O)—; or —C(═O)—; and Y1 to Y4 are (C1-C8)alkyl; (C3-C7)cycloalkyl; (C6-C20)aryl optionally substituted; or (C6-C20)heteroaryl optionally substituted; and FG1 and FG2 are H, OH, or NHR8.