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公开(公告)号:US10195605B2
公开(公告)日:2019-02-05
申请号:US15161768
申请日:2016-05-23
Applicant: EMD Millipore Corporation
Inventor: Rene Reinbigler , Jean-Louis Weissenbach
IPC: B29C49/00 , B01L3/00 , B29C33/02 , B29C49/48 , A61L2/00 , C12M1/00 , B29C65/02 , B29C49/02 , B29L31/00 , B29K23/00 , B29L9/00
Abstract: The method comprises the step of forming pipes (12) by clamping a bag between shells (13, 14) and by injecting an inflating agent via an inflating connector.The circuit comprises a bag (126) and a press (10) comprising two shells (13, 14) clamping said bag in a state in which pipes (12) are formed between the films (25, 26) of the bag.
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132.
公开(公告)号:US20190002176A1
公开(公告)日:2019-01-03
申请号:US15743361
申请日:2016-08-15
Applicant: EMD Millipore Corporation
Inventor: Stephen Proulx , David DeCoste
Abstract: A device for storing, transporting and/or handling a liquid or liquids and methods for using the device are described. The device is suitable for use with sterile or aseptic liquids, particularly with large liquid volumes such as 10-1000 liters or more, and avoids the need for bags, bins and carriers commonly used for storing and transporting large volumes of liquids. The device comprises a coiled tubing. The coiled tubing can be loaded onto a spool to support the coiled tubing. The tubing can be filled, sealed, stored and transported in a more robust manner than previously achieved with bags, bins and carriers.
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公开(公告)号:US20180372600A1
公开(公告)日:2018-12-27
申请号:US16115762
申请日:2018-08-29
Applicant: EMD Millipore Corporation
Inventor: Phillip Clark , Kurt Greenizen , John Doyle
Abstract: Fluid containment pressure vessel that eliminates the outer support housing present in certain conventional vessels, and provides an improved cap-to-body interface. In certain embodiments, the cap is threaded and configured to threadingly engage with the body of the pressure vessel, and has sufficient structural integrity to withstand the pressures in the device without the need for a support housing. In certain embodiments, an interlock mechanism is provided that prevents the cap from being opened (e.g., removed from the body) while the device is under pressure. In certain embodiments, a pressure relief valve is provided with a pre-loaded biasing mechanism to achieve the required pressure release rate. The vessel can be used for sample preparation, including purification or concentration of samples, particularly protein samples.
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公开(公告)号:US20180275043A1
公开(公告)日:2018-09-27
申请号:US15958480
申请日:2018-04-20
Applicant: EMD Millipore Corporation
Inventor: Philip Janmin Lee , Paul Ju-Sung Hung , Narendra Maheshri
IPC: G01N15/14 , B01L3/00 , G01N33/487 , G01N33/543 , G01N15/00
CPC classification number: G01N15/1484 , B01L3/502707 , B01L3/502761 , B01L2200/0668 , B01L2300/0867 , B01L2300/123 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , G01N15/1459 , G01N15/1463 , G01N15/147 , G01N15/1475 , G01N33/487 , G01N33/54366 , G01N2015/0065 , G01N2015/1493
Abstract: The method, device, and system relate to particle analysis, and in particular, to a microfluidic device designed for trapping particles for analysis. Particles include beads and cells.
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公开(公告)号:US20180275012A1
公开(公告)日:2018-09-27
申请号:US15520082
申请日:2015-12-17
Applicant: EMD Millipore Corporation
Inventor: Stephen G. Hunt , Nicholas Landry , Martin Szyk
CPC classification number: G01M3/2876 , B01D61/243 , B01D65/022 , B01D65/104 , B01D2201/167 , B01D2273/18 , B01D2313/13 , B01D2313/16 , B01D2313/18 , B01D2313/58 , B01D2313/90 , F16J15/002 , F16K1/46
Abstract: The present disclosure relates to a filter capsule that supports direct integrity testing of an internal filter element. The filter capsule includes a filter housing having an inlet port, an outlet port, a passage running longitudinally between the inlet port and outlet port and holding a filter element, and an aseptic vent assembly. The filter housing also includes an integrity test assembly that can be used as a direct connection for integrity testing hardware, as opposed to upstream of the filter capsule. In one embodiment, the integrity test assembly comprises a body having a bore formed through its interior and a movable plunger within the bore. The plunger includes a handle to move the plunger between a closed position and an open position. Various seals between the plunger and the bore form a fluid tight seal between various portions of the plunger and the bore.
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公开(公告)号:US20180214876A1
公开(公告)日:2018-08-02
申请号:US15518298
申请日:2015-10-14
Applicant: EMD Millipore Corporation
Inventor: Joseph Muldoon , Rene Reinbigler
Abstract: A fluid transfer device includes a syringe barrel having a chamber, a first plunger slidably movable inside the chamber, and a second plunger slidably movable inside the chamber. The distal end portion of the first plunger is engageable with the proximal end portion of the second plunger such that when the distal end portion of the first plunger and the proximal end portion of the second plunger are engaged, the second plunger is movable by the first plunger. A check valve may be incorporated into the distal end portion of the second plunger to allow a fluid to pass therethrough in a direction towards the proximal end portion of the second plunger and prevent a fluid to pass therethrough in a reverse direction. A fluid transfer assembly and a sampling method are also described.
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公开(公告)号:US20180169593A1
公开(公告)日:2018-06-21
申请号:US15575596
申请日:2016-08-12
Applicant: EMD Millipore Corporation
Inventor: Jad Jaber , Wilson Moya , Mikhail Kozlov
CPC classification number: B01D71/08 , B01D61/145 , B01D67/0006 , B01D67/0011 , B01D67/0013 , B01D67/0016 , B01D69/02 , B01D69/10 , B01D69/125 , B01D2323/30 , B01D2325/02 , B01D2325/04 , B01D2325/36
Abstract: The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.
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公开(公告)号:US09943616B2
公开(公告)日:2018-04-17
申请号:US15691369
申请日:2017-08-30
Applicant: EMD Millipore Corporation
Inventor: Mikhail Kozlov , Wilson Moya , Gabriel Tkacik
CPC classification number: A61L2/0017 , B01D39/1623 , B01D67/0004 , B01D67/002 , B01D69/00 , B01D2239/025 , B01D2323/39 , C02F1/444 , C02F2303/04
Abstract: A method for removing microorganisms from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention. Microorganisms such as bacteria, particularly B. Diminuta, are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a B. Diminuta LRV greater than about 9, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. Another method for removing microorganisms such as bacteria and Mycloplasma, includes passing the liquid through a porous nanofiber containing filtration medium having a microorganism LRV greater than about 8, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. The filtration medium can be in the form of a fibrous electro spun polymeric nanofiber liquid filtration medium mat.
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公开(公告)号:US20180071687A1
公开(公告)日:2018-03-15
申请号:US15562110
申请日:2016-03-10
Applicant: EMD Millipore Corporation
Inventor: Joseph M. Almasian , Mark E. Chisholm , George A. Gagne, Jr. , Martin Szyk
CPC classification number: B01D63/082 , B01D63/14 , B01D69/10 , B01D2313/025 , B01D2313/04 , B01D2319/04 , C02F1/001 , C02F2103/003 , C02F2103/343 , C02F2201/002 , C02F2203/006 , C02F2301/04 , C02F2303/04
Abstract: A membrane-based separation device comprises multiple interconnected flat sheets of membrane bonded to a flexible film. The bonded films are bonded in a way to create an accordion or zig-zag shape. In certain embodiments, the first or upstream layer is affixed to a suitable housing, and the last or most downstream layer is also affixed to the suitable housing. The housing may contain an inlet port for the introduction of sample, and an outlet port for the removal of filtered sample. Flow through the segments is in parallel. Since the membranes are not folded or pleated, higher performance membranes (e.g., polysulfone based membranes with some degree of asymmetry) than those usable in pleated or folded systems can be used.
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140.
公开(公告)号:US09910041B2
公开(公告)日:2018-03-06
申请号:US14891727
申请日:2014-04-04
Applicant: EMD Millipore Corporation
Inventor: Matthew T. Stone , Ushma Mehta , Damon Asher , Patricia Greenhalgh
IPC: C07K16/00 , C07K1/36 , C07D471/02 , C07K1/16 , C07K1/18 , G01N33/569 , C07K1/20 , C07K1/22 , C12Q1/04 , C12Q1/06
CPC classification number: G01N33/56983 , C07K1/20 , C07K1/22 , C07K16/00 , C12Q1/04 , C12Q1/06 , G01N2333/015 , G01N2333/15
Abstract: The present invention provides methods for determining whether activated carbon can be used for removing viruses or a certain virus from a sample containing a target protein.
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