POLYMERIC SYSTEMS AND USES THEREOF IN THERANOSTIC APPLICATIONS
    143.
    发明申请
    POLYMERIC SYSTEMS AND USES THEREOF IN THERANOSTIC APPLICATIONS 审中-公开
    聚合物系统及其在治疗应用中的应用

    公开(公告)号:US20170014531A1

    公开(公告)日:2017-01-19

    申请号:US15124360

    申请日:2015-03-13

    Abstract: Polymeric systems useful for theranostic applications are disclosed. The polymeric systems comprise a fluorescent or fluorogenic moiety and a therapeutically active agent, each attached to the same or different polymeric moiety. The polymeric systems are designed such that a fluorescent signal is generated in response to a chemical event, preferably upon contacting an analyte (e.g., an enzyme) that is over-expressed in a diseased tissue or organ. Probes useful for inclusion in such polymeric systems, processes of preparing such probes and the polymeric systems, and uses thereof in diagnostic and/or theranostic applications are also disclosed.

    Abstract translation: 公开了可用于有机应用的聚合体系。 聚合体系包含荧光或荧光部分和治疗活性剂,各自连接到相同或不同的聚合物部分。 聚合物体系被设计成使得响应于化学事件产生荧光信号,优选在接触在患病组织或器官中过度表达的分析物(例如酶)时产生荧光信号。 还公开了可用于包含在这种聚合物体系中的探针,制备这种探针的方法和聚合物体系,以及其在诊断和/或治疗应用中的用途。

    Angular rate sensor
    145.
    发明授权
    Angular rate sensor 有权
    角速度传感器

    公开(公告)号:US09528830B2

    公开(公告)日:2016-12-27

    申请号:US14334216

    申请日:2014-07-17

    CPC classification number: G01C19/5642 G01C19/574

    Abstract: A rotation sensing device is presented. The device comprises: a proof mass arrangement comprising at least one pair of proof masses spaced-apart from one another along a first axis; a suspension assembly comprising flexible suspension beams having a main axis deformable between their substantially straight and curved states, the suspension assembly coupling the proof masses to an anchor assembly, while allowing a drive-mode oscillatory movement of the proof masses at least along a second axis substantially perpendicular to the main axis of the beams; and an actuation mechanism configured and operable to cause the drive-mode oscillatory movement of the proof masses in opposite directions along said second axis, thereby generating a sense-mode oscillatory movement of the proof masses during the rotation of the device about at least one rotation axis perpendicular to said second axis, said sense-mode movement being indicative of a rate of the rotation.

    Abstract translation: 提出了一种旋转感测装置。 该装置包括:证明质量装置,其包括沿着第一轴线彼此间隔开的至少一对检验质量块; 悬架组件,其包括具有可在其基本上直线和弯曲状态之间变形的主轴的柔性悬挂梁,所述悬架组件将所述证明块联接到锚固组件,同时允许所述证明块的驱动模式振荡运动至少沿第二轴线 基本上垂直于梁的主轴线; 以及致动机构,其被配置和可操作以使所述证明质量块沿着所述第二轴线的相反方向的驱动模式振荡运动,从而在所述装置旋转期间产生所述证明质量块的感测模式振荡运动,该运动模式围绕至少一个旋转 垂直于所述第二轴的轴,所述感测模式运动指示旋转速率。

    APPARATUS AND METHOD FOR SNAPSHOT SPECTRAL IMAGING
    148.
    发明申请
    APPARATUS AND METHOD FOR SNAPSHOT SPECTRAL IMAGING 审中-公开
    装置和方法进行快速光谱成像

    公开(公告)号:US20160313181A1

    公开(公告)日:2016-10-27

    申请号:US14967398

    申请日:2014-06-16

    Abstract: Apparatus and method for obtaining a plurality of spectral images of a source object in a snapshot using comprising two-dimensional compressed sensing data cube reconstruction (2D CS-SCR) applied to a dispersed-diffused snapshot image. In some embodiments, the snapshot image is obtained through a RIP diffuser. In some embodiments, a randomizer is used to further randomized the dispersed-diffused snapshot image. The 2D CS-SCR includes applying a 2D framelet transform separately to arrays representing different wavebands of spectral cube data derived from the snapshot image. The application of the 2D framelet transform separately to the arrays representing the different wavebands includes application of direct and inverse 2D framelet transforms to the arrays. In some embodiments, the direct and inverse framelet transforms are included in a split Bregman iteration.

    Abstract translation: 一种用于在快照中获得源物体的多个光谱图像的装置和方法,包括应用于分散扩散的快照图像的二维压缩感测数据立方体重建(2D CS-SCR)。 在一些实施例中,通过RIP扩散器获得快照图像。 在一些实施例中,使用随机化器来进一步随机化分散扩散的快照图像。 2D CS-SCR包括将二维框架变换分别应用于表示从快照图像导出的频谱立方体数据的不同波段的阵列。 将2D框架单元变换成表示不同波段的阵列的应用包括将直接和反向的2D框架变换应用于阵列。 在一些实施例中,直接和反向帧组变换被包括在分割的Bregman迭代中。

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