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141.发明授权Catalytic processes for obtaining inorganic nanostructures by using soft metals 有权通过使用软金属获得无机纳米结构的催化方法公开(公告)号：US09527735B2
公开(公告)日：2016-12-27
申请号：US14635345
申请日：2015-03-02
Inventor： Reshef Tenne , Olga Brontvein , Jeffrey Gordon , Daniel Feuerman
IPC: H01B1/10 , C01B19/00 , H01B1/08 , C01G39/00 , C01G39/02 , C01G39/06 , C01G41/00 , C01G41/02 , C01B13/32 , C01B13/36 , B82Y30/00 , C10M125/22 , H01B1/06
CPC classification number: C01B19/007 , B82Y30/00 , C01B13/322 , C01B13/366 , C01G39/006 , C01G39/02 , C01G39/06 , C01G41/00 , C01G41/02 , C01P2002/54 , C01P2004/03 , C01P2004/04 , C01P2004/13 , C01P2004/16 , C01P2006/40 , C10M125/22 , C10M2201/065 , C10M2201/066 , H01B1/06 , H01B1/08 , H01B1/10
Abstract: The present invention concerns inorganic nanostructures comprising soft metals at low concentrations and catalytic processes utilizing soft metals for obtaining inorganic nanostructures.
Abstract translation: 本发明涉及包含低浓度的软金属和利用软金属获得无机纳米结构的催化方法的无机纳米结构。
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公开(公告)号：US09526749B2
公开(公告)日：2016-12-27
申请号：US14627593
申请日：2015-02-20
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Michael D. Walker , Yoav Soen , Revital Sharivkin
CPC classification number: A61K35/39 , C12N5/0676 , C12N2501/415 , C12N2501/50 , C12N2501/505 , C12N2501/585 , C12N2501/599 , G01N33/56966 , G01N2333/70596 , G01N2333/71 , G01N2500/10
Abstract: Methods of isolating distinct specific cell types within mixed populations of cells. Methods of isolating specific cell types among pancreatic cells, particularly from human islets of Langerhans. Markers and combinations thereof for use in methods of isolating insulin producing islet beta cells for treatment of diabetes.
Abstract translation: 在混合细胞群中分离不同特定细胞类型的方法。 在胰腺细胞，特别是胰岛细胞中分离特异性细胞类型的方法。 用于分离产生胰岛素胰岛β细胞用于治疗糖尿病的方法的标记物及其组合。
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143.发明申请(BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS 审中-公开（BACTERIO）氯仿荧光素治疗眼病和疾病公开(公告)号：US20160354468A1
公开(公告)日：2016-12-08
申请号：US15240221
申请日：2016-08-18
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Avigdor SCHERZ , Yoram SALOMON , Arie MARCOVICH , Alexander BRANDIS , Daniel WAGNER
IPC: A61K41/00 , A61K31/519 , A61N5/06 , A61K47/18 , A61K9/00 , A61K31/407 , A61K47/36
CPC classification number: A61K41/0071 , A61K9/0048 , A61K31/407 , A61K31/519 , A61K31/555 , A61K47/186 , A61K47/36 , A61N5/062 , A61N2005/0659
Abstract: An ophthalmic composition is provided, comprising chlorophyll or bacteriochlorophyll compounds for photodynamic treatment (PDT) of diseases, disorders and conditions associated with corneal or scleral anomalies, such as corneal thinning and scleral stretching.
Abstract translation: 提供了一种眼用组合物，其包含用于光动力学治疗（PDT）的叶绿素或细菌叶绿素化合物，所述疾病，病症和病症与角膜或巩膜异常相关，例如角膜变薄和巩膜拉伸。
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144.发明申请ATTENUATION OF ENCRUSTATION OF MEDICAL DEVICES USING COATINGS OF INORGANIC FULLERENE-LIKE NANOPARTICLES 审中-公开使用无机富勒烯类纳米粒子涂层对医疗器械进行加强的衰减公开(公告)号：US20160331874A1
公开(公告)日：2016-11-17
申请号：US15109822
申请日：2015-01-06
Inventor： Reshef TENNE , David ZBAIDA , Racheli RON , Ilan KAFKA , Ilan LEIBOVITZ
CPC classification number: A61L31/088 , A61L29/106 , A61L29/14 , A61L29/18 , A61L31/082 , A61L31/14 , A61L31/18 , A61L2400/12 , A61L2420/02
Abstract: A new approach is presented to reduce encrustation of catheters by the application of nanoparticles. It is demonstrated that the negatively surface charged nanoparticles produce coating films comprised of long-range domains in which the nanoparticles are self-assembled into a mosaic-like order, showing a relatively small tendency to agglomerate.
Abstract translation: 提出了一种新方法，通过应用纳米颗粒来减少导尿管的结垢。 证明负表面带电的纳米颗粒产生包括远距离域的涂膜，其中纳米颗粒自组装成马赛克状的顺序，显示出相对较小的附聚倾向。
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公开(公告)号：US20160294224A1
公开(公告)日：2016-10-06
申请号：US15177418
申请日：2016-06-09
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yaron SILBERBERG , Haim SUCHOWSKI , Nikolay V. VITANOV , Andon A. RANGELOV
Abstract: A method or apparatus for wireless transferring energy between a source coil and a drain coil, comprises setting an initial resonant frequency of the source coil as a first condition; setting the source coil and said drain coil in positions relative to each other to define an initial coupling coefficient therebetween, so that the initial coupling coefficient comprises a second condition; and adiabatically changing one or both of the conditions while pumping energy into the source coil. The source coil energy is transferred to the drain coil over the course of the adiabatic change.
Abstract translation: 一种用于在源极线圈和漏极线圈之间无线传输能量的方法或装置，包括将源极线圈的初始谐振频率设置为第一条件; 将源极线圈和所述漏极线圈设置在相对于彼此的位置以限定其间的初始耦合系数，使得初始耦合系数包括第二条件; 并绝热地改变一个或两个条件，同时将能量泵入源线圈。 在绝热变化的过程中，源极线圈能量被传递到漏极线圈。
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Patent Agency Ranking
公开(公告)号：US20160279169A1
公开(公告)日：2016-09-29
申请号：US15180152
申请日：2016-06-13
Inventor： Daniel OFFEN , Michal DADON-NACHUM , Tali BEN-ZUR , Eldad MELAMED , David YAFFE
CPC classification number: A61K35/34 , A61K35/12 , A61K38/00 , A61K38/185 , A61K38/1866 , A61K38/30 , C12N5/0658 , C12N5/0659 , C12N2501/105 , C12N2501/13 , C12N2501/165 , C12N2510/00
Abstract: An isolated muscle progenitor cell being MyoD positive, CD34 negative and CD45 negative is disclosed. The muscle progenitor cell is genetically modified to express at least one neurotrophic factor. In addition, cell populations are disclosed, comprising at least four subpopulations of muscle cells each being genetically modified to express a different neurotrophic factor, wherein said neurotrophic factor is selected from the group consisting of glial derived neurotrophic factor (GDNF), insulin growth factor (IGF-1), vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). Uses of the cell populations are also disclosed.
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147.发明申请SELECTIVE INHIBITORS OF ALPHA2 ISOFORM OF Na,K-ATPase AND USE FOR REDUCTION OF INTRA-OCULAR PRESSURE 有权ALPHA2的选择性抑制剂Na，K-ATP酶的鉴定和用于减少内压的用途公开(公告)号：US20160244479A1
公开(公告)日：2016-08-25
申请号：US14913366
申请日：2014-08-27
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor： Steven J.D. KARLISH , Adriana KATZ , Daniel M. TAL
IPC: C07J43/00
CPC classification number: C07J43/003 , C07J19/005
Abstract: The present invention relates to digoxin and digitoxin derivatives that are selective inhibitors of the α2 isoform of Na,K-ATPase, and that reduce intra-ocular pressure. The invention further relates to uses of these derivatives for treating disorders associated with elevated intraocular pressure, such as glaucomas, and/or as cardiotonic agents.
Abstract translation: 本发明涉及作为Na，K-ATP酶的α2同种型的选择性抑制剂的地高辛和洋地黄毒苷衍生物，并且降低眼内压。 本发明进一步涉及这些衍生物用于治疗与眼内压升高相关的疾病，例如青光眼，和/或作为强心剂。
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148.发明授权公开(公告)号：US09387264B2
公开(公告)日：2016-07-12
申请号：US13856788
申请日：2013-04-04
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD , THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV
Inventor： Michal Neeman , Raz Zarivach , Marina Radoul , Batya Cohen , Moriel Vandsburger , Limor Lewin
IPC: A61K49/14 , C07K14/47 , C07K14/195
CPC classification number: A61K49/14 , C07K14/195 , C07K14/47 , C07K2319/00 , C07K2319/42
Abstract: The invention provides a fusion ferritin protein wherein a ferritin heavy chain polypeptide is fused to a peptide, wherein the peptide is fused to the C-terminal end of the ferritin heavy chain; and the peptide includes at least a portion of a Mms6 protein sequence and at least one heterologous amino acid at its N-terminal end. The invention further provides methods of use of the ferritin fusion protein for Magnetic Resonance Imaging.
Abstract translation: 本发明提供融合铁蛋白，其中铁蛋白重链多肽与肽融合，其中该肽融合到铁蛋白重链的C末端; 并且肽在其N-末端包括至少一部分Mms6蛋白序列和至少一个异源氨基酸。 本发明还提供了用于磁共振成像的铁蛋白融合蛋白的使用方法。
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公开(公告)号：US09382293B2
公开(公告)日：2016-07-05
申请号：US14384685
申请日：2013-03-14
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Michal Eisenbach-Schwartz , Matityahu Fridkin , Michal Cardon-Yaakov
CPC classification number: C07K7/06 , A61K9/0053 , A61K38/00 , C07K7/64
Abstract: The present application provides synthetic modified peptides of five to seven natural or non-natural amino acids as well as pharmaceutical compositions comprising them, for use in the treatment a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, depression or cognitive impairment, particularly schizophrenia and Alzheimer's disease.
Abstract translation: 本申请提供五至七个天然或非天然氨基酸的合成修饰肽以及包含它们的药物组合物，用于治疗与感觉门控功能障碍，抑郁症或认知障碍相关的行为异常的疾病或病症 ，特别是精神分裂症和阿尔茨海默病。
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150.发明申请ARTIFICIAL CELLULOSOMES COMPRISING MULTIPLE SCAFFOLDS AND USES THEREOF IN BIOMASS DEGRADATION 审中-公开包含多种镰刀菌的人造细胞及其在生物质降解中的用途公开(公告)号：US20160186156A1
公开(公告)日：2016-06-30
申请号：US14910001
申请日：2014-08-03
Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
Inventor： Edward A. BAYER , Yael VAZANA , Yoav BARAK , Johanna STERN , Hadar GILARY , Sarah MORAIS
CPC classification number: C12N9/2437 , C07K2319/20 , C07K2319/70 , C12N9/16 , C12N9/24 , C12N9/88 , C12N9/96 , C12N11/12 , C12N11/18 , C12N15/62 , C12P19/02 , C12P19/14 , C12Y302/01004 , Y02E50/16
Abstract: Multi-enzyme complexes comprising an array of scaffold subunits designed for efficient integration of a plurality of carbohydrate-active enzymes are provided.
Abstract translation: 提供了包含设计用于多个碳水化合物活性酶的有效整合的支架亚基阵列的多酶复合物。
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