公开(公告)号：US09745427B2

公开(公告)日：2017-08-29

申请号：US13931951

申请日：2013-06-30

Applicant: King Abdulaziz City for Science and Technology

Inventor： Ahmed Ali Basfar ,  Salah Lofty Ahmed Khalil

IPC: C08F2/46 ,  C08F2/50 ,  C08G61/04 ,  C08J3/24 ,  C08J3/28 ,  B29C61/00

CPC classification number: C08J3/246 ,  B29C61/003 ,  C08J3/24 ,  C08J3/28 ,  C08J2329/04 ,  C08J2435/02 ,  C08K3/041 ,  C08K5/07 ,  C08K7/24 ,  C08L29/04 ,  C08L33/14 ,  C08L2201/12

Abstract: Shape memory polymers (SMP) based on poly vinyl alcohol (PVA) in the presence of 2-carboxyethyl acrylate oligomers (CEA), multi-wall carbon nanotubes (MWCNTs) and cross linked by ionizing radiation were investigated. Chemical crosslinking by glutaraldehyde for PVA in the presence of CEA and MWCNTs was also studied. Radiation cross linked SMP exhibits good temperature responsive shape memory behavior as demonstrated by thermal properties of radiation investigated by dynamic mechanical analysis. Transition temperature at Tan δ of radiation cross linked SMP decreased significantly by 6 and 13° C. due to addition of MWCNTs. The developed SMP exhibited promising shape memory behavior of radiation cross linked SMP for biomedical applications between temperatures range of Tan δ. Results on the gel fraction revealed significant reduction in swelling and increase in gelation due to chemical cross linking with glutaraldehyde. The radiation cross linked SMP reached 100% gelation at an irradiation dose of 50 kGy.

公开(公告)号：US09700077B2

公开(公告)日：2017-07-11

申请号：US13921869

申请日：2013-06-19

Applicant: NIKE, Inc.

Inventor： Michael R. Baron ,  Karin E. Carter ,  Sophie L. Mather ,  LaShurya M. Wise

IPC: A41B1/00 ,  A41D27/28 ,  A41D31/00 ,  A41D1/04 ,  D04B21/16 ,  D02G3/44 ,  A41D13/005

CPC classification number: A41B1/00 ,  A41D1/04 ,  A41D13/0053 ,  A41D27/28 ,  A41D31/0033 ,  A41D2400/20 ,  C08L2201/12 ,  D02G3/44 ,  D04B21/16 ,  D04B21/207 ,  D10B2401/02

Abstract: An article of apparel may include a torso region with a front area, a back area, and a pair of side areas. At least a portion of each of the side areas are formed from a material with (a) a first air permeability when unexposed to water and (b) a second air permeability when exposed to water. The first air permeability may be less than 279 cm3/second per cm2 measured in accordance with ASTM D 737, and the second air permeability may be greater than 279 cm3/second per cm2 measured in accordance with ASTM D 737. In some configurations, at least a portion of the back area may be formed from the material. The article of apparel may be a shirt, and the article of apparel may include arm regions that extend outward from the torso region.

公开(公告)号：US20170143582A1

公开(公告)日：2017-05-25

申请号：US15355877

申请日：2016-11-18

Applicant: Piri MILLER

Inventor： Piri MILLER

IPC: A61H19/00

CPC classification number: A61H19/34 ,  A61H19/40 ,  A61H23/02 ,  A61H2201/0165 ,  A61H2201/1645 ,  A61H2201/169 ,  A61H2201/1695 ,  A61H2201/50 ,  A61H2201/5097 ,  C08L2201/12

Abstract: A device for use by a female that includes an external housing, an internal skeleton, and a motorized portion. The external housing is configured to conform to the user's shape and form. The internal skeleton may be deformed by the user as desired. The internal skeleton includes shape-memory properties so that after deformation, the device retains the shape desired by the user. The motorized portion is secured within the external housing so that desired portions of the device receive the majority of the stimulation provided by the motorized portion.

公开(公告)号：US09610328B2

公开(公告)日：2017-04-04

申请号：US13582900

申请日：2011-03-07

Applicant: David J. Mooney ,  Cristina Borselli ,  Herman Vandenburgh ,  Dimitry Shvartsman ,  Hannah Storrie ,  Jeff Lichtman

Inventor： David J. Mooney ,  Cristina Borselli ,  Herman Vandenburgh ,  Dimitry Shvartsman ,  Hannah Storrie ,  Jeff Lichtman

IPC: A01N63/00 ,  C12N5/00 ,  A61K38/18 ,  A61K38/30 ,  A61L27/36 ,  A61L27/38 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61K35/34 ,  A61K35/12

CPC classification number: A61K38/30 ,  A61K9/06 ,  A61K9/19 ,  A61K35/12 ,  A61K35/34 ,  A61K38/18 ,  A61K38/1866 ,  A61L27/20 ,  A61L27/3612 ,  A61L27/3826 ,  A61L27/3873 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/414 ,  A61L2400/06 ,  A61L2400/16 ,  A61L2430/32 ,  C08L2201/12 ,  A61K2300/00

Abstract: An improved device and method for extended repair and regeneration of muscle tissue. An exemplary device comprises (a) a scaffold comprising an ECM component; (b) a combination of growth factors such as VEGF and IGF; and (c) a population of myogenic cells. Implantation of the device leads to muscle regeneration and repair over an extended period of time.

公开(公告)号：US09486302B2

公开(公告)日：2016-11-08

申请号：US14059231

申请日：2013-10-21

Applicant: NANYANG TECHNOLOGICAL UNIVERSITY

Inventor： Yin Chiang Freddy Boey ,  Zheng Wang ,  Joseph Tang

IPC: A61F2/00 ,  A61L27/34 ,  A61L27/56 ,  A61L31/10 ,  A61L31/14 ,  B32B27/08 ,  B32B5/14 ,  B32B9/02 ,  B32B9/04 ,  B32B27/16 ,  B32B27/18 ,  B32B27/30 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B3/26 ,  B32B3/30 ,  A61L31/04 ,  A61F2/24

CPC classification number: A61F2/0063 ,  A61F2/2481 ,  A61F2250/0031 ,  A61F2250/0067 ,  A61L27/34 ,  A61L27/56 ,  A61L31/048 ,  A61L31/10 ,  A61L31/146 ,  B32B3/266 ,  B32B3/30 ,  B32B5/142 ,  B32B9/02 ,  B32B9/04 ,  B32B9/045 ,  B32B27/08 ,  B32B27/16 ,  B32B27/18 ,  B32B27/302 ,  B32B27/304 ,  B32B27/308 ,  B32B27/32 ,  B32B27/322 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B2255/10 ,  B32B2255/26 ,  B32B2264/02 ,  B32B2264/10 ,  B32B2270/00 ,  B32B2307/538 ,  B32B2307/546 ,  B32B2307/706 ,  B32B2307/744 ,  B32B2307/746 ,  B32B2535/00 ,  C08L2201/12 ,  C08L27/16

Abstract: The present invention generally relates to the field of prostheses for surgical applications, to methods of their manufacturing and to methods of treating a patient by implanting them into a patient. More particularly, the present invention relates to prostheses having a multi-layered sheet structure and their use in hernia repair, the repair of anatomical defects of the abdominal wall, diaphragm, and chest wall, correction of defects in the genitourinary system, and repair of traumatically damaged organs such as the spleen, liver or kidney.

Abstract translation: 本发明一般涉及用于外科应用的假体领域，其制造方法以及通过将患者植入患者来治疗患者的方法。 更具体地，本发明涉及具有多层片结构的假体及其在疝修补中的应用，修复腹壁，隔膜和胸壁的解剖缺陷，修正泌尿生殖系统中的缺陷以及修复 创伤性损伤的器官如脾脏，肝脏或肾脏。

公开(公告)号：US09447253B2

公开(公告)日：2016-09-20

申请号：US14437014

申请日：2013-11-20

Applicant: Robert Weiss ,  Ying Shi ,  Mitra Yoonesi

Inventor： Robert Weiss ,  Ying Shi ,  Mitra Yoonesi

IPC: C08K5/098 ,  C08K5/17 ,  C08L71/10 ,  B29C41/12 ,  C08K5/19 ,  G02B1/04

CPC classification number: C08K5/098 ,  B29C41/12 ,  C08G2280/00 ,  C08K5/17 ,  C08K5/19 ,  C08L71/10 ,  C08L2201/12 ,  C08L2666/34 ,  C08L2666/36 ,  C08L2666/66 ,  G02B1/04

Abstract: A shape memory composition includes a high temperature ionomer having a glass transition temperature or a melting temperature of 100° C. or greater and a modulus at room temperature of 1×108 Pa or greater, the high temperature ionomer including a polymer with ionic units either within the backbone of the polymer or pendant to the backbone or both. The shape memory composition includes crystalline or glassy domains of a low molecular weight non-polymeric compound dispersed in the high temperature ionomer and interacting the ionic units of the high temperature ionomer to form a secondary network characterized by being a reversible network in that it is compromised by the heating of the low molecular weight non-polymeric compound to change out of its crystalline or glassy phase.

Abstract translation: 形状记忆组合物包括具有玻璃化转变温度或熔融温度为100℃以上的高温离聚物，室温下的模量为1×10 8 Pa以上，高温离聚物包含具有离子单元的聚合物 在聚合物的主链或侧链中的骨架或两者。 形状记忆组合物包括分散在高温离聚物中的低分子量非聚合化合物的结晶或玻璃状结构域，并与高温离子交联聚合物的离子单元相互作用以形成二次网络，其特征在于可逆网络，因为其被破坏 通过加热低分子量非聚合物以改变其结晶或玻璃态。

公开(公告)号：US09427342B2

公开(公告)日：2016-08-30

申请号：US14577777

申请日：2014-12-19

Applicant: Cook Medical Technologies LLC

Inventor： James M. Carlson ,  Shyam S. V. Kuppurathanam ,  Fred T. Parker ,  Rebecca Sue Todd

IPC: A61F2/07 ,  A61F2/90 ,  A61L31/02 ,  A61L31/04 ,  A61L31/14 ,  D02G3/12 ,  D02G3/44 ,  D03D3/02 ,  D03D13/00 ,  D03D15/00 ,  D03D15/08 ,  A61F2/06

CPC classification number: A61F2/90 ,  A61F2/06 ,  A61F2/07 ,  A61F2002/075 ,  A61F2210/0014 ,  A61L31/022 ,  A61L31/041 ,  A61L31/14 ,  A61L2400/16 ,  C08L2201/12 ,  D02G3/12 ,  D02G3/448 ,  D03D3/02 ,  D03D13/004 ,  D03D13/008 ,  D03D15/00 ,  D03D15/08 ,  D10B2101/20 ,  D10B2321/021 ,  D10B2321/022 ,  D10B2321/042 ,  D10B2331/04 ,  D10B2331/10 ,  D10B2401/046 ,  D10B2401/061 ,  D10B2509/06

Abstract: The disclosure relates to a woven fabric for use in an implantable medical device. The woven fabric comprises shape memory element strands woven with textile strands. At least one of the shape memory element strands has at least one float of at least five textile strands between binding points.

Abstract translation: 本公开涉及用于可植入医疗装置的机织织物。 机织织物包括用织物股线编织的形状记忆元件股线。 形状记忆元件股线中的至少一个在结合点之间具有至少一个至少五个纺织股线的浮子。

公开(公告)号：US09339331B2

公开(公告)日：2016-05-17

申请号：US12345606

申请日：2008-12-29

Applicant: Troy T. Tegg ,  Richard E. Stehr

Inventor： Troy T. Tegg ,  Richard E. Stehr

IPC: A61B18/14 ,  A61B18/00 ,  A61B17/00 ,  A61B19/00

CPC classification number: A61B5/042 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61B2090/065 ,  A61B2218/002 ,  C08L2201/12

Abstract: Catheter systems and methods are disclosed. An exemplary catheter includes an outer tubing housing and an inner fluid delivery tubing, the inner fluid delivery tubing having at least one fluid delivery port. The catheter also includes a deployment member movable axially within the inner fluid delivery tubing. A plurality of splines are each connected at a proximal end to the outer tubing and at a distal end to deployment member. A seal is provided between the outer tubing and the inner fluid delivery tubing. A gasket is provided between the deployment member and the inner fluid delivery tubing. Both the seal and the gasket are configured to prevent blood or other fluid from ingressing into the outer tubing.

Abstract translation: 公开了导管系统和方法。 示例性导管包括外管壳体和内流体输送管，内流体输送管具有至少一个流体输送端口。 导管还包括可在内部流体输送管内轴向移动的展开构件。 多个花键各自在近端连接到外管，并且在末端连接到展开构件。 在外管和内流体输送管之间提供密封。 在展开构件和内部流体输送管之间设置垫圈。 密封件和垫圈均被配置成防止血液或其他流体进入外管。

公开(公告)号：US20160096015A1

公开(公告)日：2016-04-07

申请号：US14966827

申请日：2015-12-11

Applicant: REGION HOVEDSTADEN v/HERLEV HOSPITAL

Inventor： Karen Julie GEHL ,  Karsten VIDEBÆK

IPC: A61N1/32 ,  A61N1/05

CPC classification number: A61N1/327 ,  A61B18/1477 ,  A61B2017/00867 ,  A61B2018/00083 ,  A61B2018/00613 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B2018/1495 ,  A61B2218/002 ,  A61N1/05 ,  A61N1/0502 ,  C08L2201/12

Abstract: A method of generating an electric field in a target region of a patient includes inserting a set of electrodes having respective distal ends enclosed within a single elongate introducer shaft having a distal tip, into the vicinity of the target region; extending at least a pair of the electrodes to an extended position such that the electrode distal ends are deflected away from a longitudinal axis of the shaft in such a way that at least one planar projection taken in a plane perpendicular to the longitudinal axis of a distance between a pair of distal ends of the electrodes is larger than a maximal extent of a cross-section of the introducer shaft, the cross-section taken in a plane perpendicular to the a longitudinal axis at a distal end of the introducer shaft; and applying one or more electric pulses to the target tissue through the electrodes.

Abstract translation: 在患者的目标区域中产生电场的方法包括将具有封闭在具有远端尖端的单个细长导引器轴内的各个远端的一组电极插入目标区域附近; 将至少一对电极延伸到延伸位置，使得电极远端从轴的纵向轴线偏转，使得至少一个平面突出部在垂直于纵向轴线的平面的一段距离 在电极的一对远端之间大于引导器轴的横截面的最大范围，该横截面在与引导器轴的远端处的纵向轴线垂直的平面中截取; 以及通过电极向目标组织施加一个或多个电脉冲。

公开(公告)号：US09216100B2

公开(公告)日：2015-12-22

申请号：US13375261

申请日：2009-05-30

Applicant: Jürgen Seibold ,  Erhard Müller ,  Karel Volenec ,  Petr Sittner ,  Ludek Heller ,  Jan Pilch

Inventor： Jürgen Seibold ,  Erhard Müller ,  Karel Volenec ,  Petr Sittner ,  Ludek Heller ,  Jan Pilch

IPC: A61F2/06 ,  A61F2/90 ,  A61F2/07 ,  A61L31/02 ,  A61L31/10 ,  A61L31/14 ,  D02G3/36 ,  D02G3/44 ,  D03D3/02 ,  D03D13/00 ,  D03D15/00 ,  D03D27/00

CPC classification number: A61F2/90 ,  A61F2/06 ,  A61F2/07 ,  A61F2002/075 ,  A61L31/022 ,  A61L31/10 ,  A61L31/14 ,  A61L2400/16 ,  C08L2201/12 ,  D02G3/36 ,  D02G3/448 ,  D03D3/02 ,  D03D13/004 ,  D03D13/008 ,  D03D15/0027 ,  D03D15/0077 ,  D03D27/00 ,  D10B2401/046 ,  D10B2509/06 ,  C08L67/02

Abstract: A medical device includes yarns made of a shape memory material and polymer yarns, wherein the yarns made of said shape memory material include polymer sheathing.

Abstract translation: 医疗装置包括由形状记忆材料和聚合物纱线制成的纱线，其中由所述形状记忆材料制成的纱线包括聚合物护套。