公开(公告)号：US08722802B2

公开(公告)日：2014-05-13

申请号：US13380455

申请日：2010-06-24

Applicant: Joachim Berthold ,  Bernd Lothar Marczinke ,  Diana Doetsch ,  Johannes-Gerhard Müller

Inventor： Joachim Berthold ,  Bernd Lothar Marczinke ,  Diana Doetsch ,  Johannes-Gerhard Müller

IPC: C08F8/00 ,  C08L23/00

CPC classification number: C08L23/0815 ,  C08L2203/16 ,  C08L2205/025 ,  C08L2207/068 ,  C08L2308/00 ,  C08L2314/02

Abstract: A novel polyethylene composition is described. The composition is suitable for manufacturing especially stretched bands or tapes, also coined raffia in the art.

Abstract translation: 描述了一种新型聚乙烯组合物。 该组合物适用于制造特别是拉伸的条带或带子，也是本领域中制造的拉法。

公开(公告)号：US08721579B2

公开(公告)日：2014-05-13

申请号：US12962626

申请日：2010-12-07

Applicant: Gerhard Müller-Spanka ,  Hans-Reinhard Zerkowski

Inventor： Gerhard Müller-Spanka ,  Hans-Reinhard Zerkowski

IPC: A61M1/36 ,  A61M1/34 ,  A61M1/16 ,  F16K31/00 ,  F16K35/00

CPC classification number: A61M1/34 ,  A61M1/1698 ,  A61M1/32 ,  A61M1/3403 ,  A61M1/3612 ,  A61M1/3621 ,  A61M1/3626 ,  A61M1/3627 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3646 ,  A61M1/3666 ,  A61M1/3693 ,  A61M39/281 ,  A61M2016/0015 ,  A61M2205/3331 ,  A61M2205/505 ,  A61M2209/08 ,  F04B43/12 ,  F16K31/00 ,  F16K35/00

Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure such as cardiopulonary bypass graft surgery, keyhole cardiopulonary bypass graft surgery, percutaneous angioplasty, percutaneous stent placement, and percutaneous etherectomy.

Abstract translation: 用于提供体外血液循环和氧合控制的装置和方法包括血液的多级脱气以提供自动化的心肺置换，以在诸如心肺旁路移植手术，锁孔心肺旁路移植手术，经皮血管成形术，经皮的医学过程中维持患者的生命 支架置入和经皮钝性。

公开(公告)号：US06898106B2

公开(公告)日：2005-05-24

申请号：US10458965

申请日：2003-06-11

Applicant: Heinz Hoenigschmid ,  Gerhard Müller

Inventor： Heinz Hoenigschmid ,  Gerhard Müller

IPC: G11C8/02 ,  G11C11/15 ,  G11C11/22 ,  H01L21/8246 ,  H01L27/105

CPC classification number: G11C11/22

Abstract: A memory device is configured to guarantee a high degree of flexibility and a compact construction. To this end, the existing plate line device of the memory device which functions on the basis of a hysteresis process is configured to detect the state of a memory capacitor and hence, the information that is stored.

Abstract translation: 存储器件被配置为保证高度的灵活性和紧凑的结构。 为此，基于滞后处理起作用的存储器件的现有板线器件被配置为检测存储电容器的状态，并因此检测存储的信息。

公开(公告)号：US06716014B2

公开(公告)日：2004-04-06

申请号：US09767452

申请日：2001-01-23

Applicant: Klaus Schäfer ,  Dieter Wiemer ,  Detlev Schulz ,  Hansjörg Meise ,  Ulrich Enders ,  Hans-Gerhard Hutter ,  Peter Senge ,  Roland Nitschke ,  Gerhard Müller

Inventor： Klaus Schäfer ,  Dieter Wiemer ,  Detlev Schulz ,  Hansjörg Meise ,  Ulrich Enders ,  Hans-Gerhard Hutter ,  Peter Senge ,  Roland Nitschke ,  Gerhard Müller

IPC: D01D5092

CPC classification number: D01D5/092

Abstract: A melt spinning apparatus for spinning a synthetic yarn, wherein the yarn is formed by combining a plurality of filaments and wound to a package by means of a takeup device downstream of the spinning apparatus. Downstream of the spinneret, an inlet cylinder with a gas-permeable wall and a cooling tube are arranged. The cooling tube connects to a suction device such that an air stream forms in the cooling tube in the direction of the advancing yarn. This air stream assists the advance of the filaments and leads to a delayed cooling. To ensure adequate cooling of the filaments within the cooling zone, an air supply device is provided for generating an additional cooling air stream which flows in the axial direction of the cooling tube for cooling the filaments downstream of the inlet to the cooling tube.

Abstract translation: 一种用于纺丝合成纱线的熔融纺丝设备，其中纱线通过组合多根细丝而形成，并通过纺丝设备下游的卷取装置卷绕到包装上。 在喷丝头的下游配置有具有气体透过壁的入口筒和冷却管。 冷却管连接到抽吸装置，使得沿着前进纱线的方向在冷却管中形成空气流。 这种气流有助于长丝的推进并导致延迟的冷却。 为了确保冷却区内的细丝的充分冷却，提供了一个空气供应装置，用于产生一个额外的冷却空气流，该冷却空气流在冷却管的轴向方向上流动，以冷却冷却管入口下游的细丝。

公开(公告)号：US06462074B1

公开(公告)日：2002-10-08

申请号：US09600355

申请日：2000-07-14

Applicant: Andreas Stolle ,  Horst-Peter Antonicek ,  Stephen Lensky ,  Arnd Voerste ,  Thomas Müller ,  Jörg Baumgarten ,  Karsten von dem Bruch ,  Gerhard Müller ,  Udo Stropp ,  Ervin Horváth ,  Jean-Marie-Viktor de Vry ,  Rudy Schreiber

Inventor： Andreas Stolle ,  Horst-Peter Antonicek ,  Stephen Lensky ,  Arnd Voerste ,  Thomas Müller ,  Jörg Baumgarten ,  Karsten von dem Bruch ,  Gerhard Müller ,  Udo Stropp ,  Ervin Horváth ,  Jean-Marie-Viktor de Vry ,  Rudy Schreiber

IPC: A61K31343

CPC classification number: C07D401/10 ,  C07D307/88 ,  C07D401/12 ,  C07D405/06 ,  C07D405/10 ,  C07D405/12 ,  C07D407/12 ,  C07D409/06 ,  C07D409/12 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14 ,  C07D417/10 ,  C07D417/12

Abstract: The present invention relates to novel substituted (&agr;,&bgr;-fused butyrolactones, to processes for their preparation and to their use for the prevention and/or treatment of disorders caused by hyper- or hypofunction of the glutamatergic system, in particular of cerebral ischaemias, craniocerebral trauma, states of pain or CNS-mediated spasms.

Abstract translation: 本发明涉及新的取代的（α，β-稠合丁内酯，其制备方法及其用于预防和/或治疗由谷氨酸能系统，特别是脑缺血性系统的过度功能或功能不全引起的疾病的用途， 颅脑创伤，疼痛状态或CNS介导的痉挛状态。

公开(公告)号：US09090719B2

公开(公告)日：2015-07-28

申请号：US13375766

申请日：2010-05-27

Applicant: Joachim Berthold ,  Bernd Lothar Marczinke ,  Diana Doetsch ,  Iakovos Vittorias ,  Dieter Lilge ,  Heinz Vogt ,  Johannes-Gerhard Müller

Inventor： Joachim Berthold ,  Bernd Lothar Marczinke ,  Diana Doetsch ,  Iakovos Vittorias ,  Dieter Lilge ,  Heinz Vogt ,  Johannes-Gerhard Müller

IPC: C08L23/06 ,  C08F10/02 ,  C08F10/00 ,  C08F210/16 ,  C08L23/08

CPC classification number: C08F10/00 ,  C08F210/16 ,  C08L23/06 ,  C08L23/0815 ,  C08L2205/035 ,  C08L2207/068 ,  C08L2314/02 ,  C08F4/6555 ,  C08F2/001 ,  C08L2666/02 ,  C08F210/08 ,  C08F2500/05 ,  C08F2500/07 ,  C08F2500/09 ,  C08F2500/12 ,  C08F2500/17 ,  C08F2500/19 ,  C08F2500/26

Abstract: Novel polyethylenes having defined molecular weight distribution and LCB structure are devised, for films or moldings.

Abstract translation: 设计了具有限定分子量分布和LCB结构的新型聚乙烯，用于薄膜或模制品。

公开(公告)号：US09027590B2

公开(公告)日：2015-05-12

申请号：US13617273

申请日：2012-09-14

Applicant: Torsten Gerlich ,  Gerhard Müller-Riederer

Inventor： Torsten Gerlich ,  Gerhard Müller-Riederer

IPC: F16K31/06 ,  F16K17/06 ,  F16K17/196 ,  F16K24/00 ,  F16K15/18 ,  B60K15/035 ,  F16K39/02 ,  F16K24/04 ,  B60K15/03

CPC classification number: B60K15/035 ,  B60K15/03519 ,  B60K2015/03296 ,  B60K2015/03561 ,  F16K24/04 ,  F16K31/0655 ,  F16K39/024 ,  Y10T137/7761 ,  Y10T137/778 ,  Y10T137/87507

Abstract: A ventilation arrangement for the head space of the fuel tank of a vehicle comprises a switchable main valve intended for adjusting an arbitrary pressure in the head space of the tank. By way of the opening position of the main valve, a connection between a connection (5) intended for connection to the head space and a connection (6) intended for connection to the surrounding atmosphere is established, wherein the main valve is assigned a pilot valve, which opens during a first path element of a switching movement, wherein the main valve only opens following this first path element. Because of the small cross section of the pilot valve and the pressure relief that materialized through its opening, the switching power can be reduced and a smaller size drive can be employed.

Abstract translation: 用于车辆的燃料箱的顶部空间的通风装置包括用于调节罐的顶部空间中的任意压力的可切换主阀。 通过主阀的打开位置，建立了用于连接到顶部空间的连接件（5）和用于连接到周围大气的连接件（6）之间的连接，其中主阀被分配有导向件 阀，其在切换运动的第一路径元件期间打开，其中主阀仅在该第一路径元件之后打开。 由于先导阀的小横截面和通过其开口实现的压力释放，可以减小开关功率并且可以采用更小尺寸的驱动。

公开(公告)号：US08084457B2

公开(公告)日：2011-12-27

申请号：US10572043

申请日：2004-09-15

Applicant: Axel Choidas ,  Alexander Backes ,  Matt Cotten ,  Ola Engkvist ,  Beatrice Felber ,  Achim Freisleben ,  Klaus Godl ,  Zoltán Greff ,  Peter Habenberger ,  Doris Hafenbradl ,  Christian Hartung ,  Thomas Herget ,  Edmund Hoppe ,  Bert Klebl ,  Andrea Missio ,  Gerhard Müller ,  Wilfried Schwab ,  Birgit Zech ,  Jose Bravo ,  John Harris ,  Joelle Le ,  Jackie Macritchie ,  Vladimir Savic ,  Brad Sherborne ,  Don Simpson

Inventor： Axel Choidas ,  Alexander Backes ,  Matt Cotten ,  Ola Engkvist ,  Beatrice Felber ,  Achim Freisleben ,  Klaus Godl ,  Zoltán Greff ,  Peter Habenberger ,  Doris Hafenbradl ,  Christian Hartung ,  Thomas Herget ,  Edmund Hoppe ,  Bert Klebl ,  Andrea Missio ,  Gerhard Müller ,  Wilfried Schwab ,  Birgit Zech ,  Jose Bravo ,  John Harris ,  Joelle Le ,  Jackie Macritchie ,  Vladimir Savic ,  Brad Sherborne ,  Don Simpson

IPC: A01N43/54 ,  C07D239/42 ,  C07D401/04 ,  C07D239/00 ,  C07D239/02

CPC classification number: C04B35/632 ,  C07D239/42 ,  C07D239/48 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12

Abstract: The present invention relates to 4,6-disubstituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, and pharmaceutical compositions containing at least one of said 4,6-di substituted aminopyrimidine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said 4,6-disubstituted aminopyrimidine derivatives as inhibitors for a protein kinase and a medium comprising at least one of said 4,6-disubstituted aminopyrimidine derivatives in an immobilized form and the use of said medium for enriching, purifying and/or depleting nucleotide binding proteins which bind to the immobilized 4,6-disubstituted aminopyrimidine derivatives.

Abstract translation: 本发明涉及4,6-二取代的氨基嘧啶衍生物和/或其药学上可接受的盐，这些衍生物作为药物活性剂的用途，特别是用于预防和/或治疗感染性疾病，包括机会性疾病，朊病毒疾病，免疫学 疾病，自身免疫疾病，双相和临床疾病，心血管疾病，细胞增殖性疾病，糖尿病，炎症，移植排斥，勃起功能障碍，神经变性疾病和中风，以及含有所述4,6-二取代氨基嘧啶衍生物和 /或其药学上可接受的盐。 此外，本发明涉及所述4,6-二取代氨基嘧啶衍生物作为蛋白激酶的抑制剂和包含至少一种固定化形式的所述4,6-二取代氨基嘧啶衍生物的介质和使用所述培养基 用于富集，纯化和/或消除与固定的4,6-二取代氨基嘧啶衍生物结合的核苷酸结合蛋白。

公开(公告)号：US20110294113A1

公开(公告)日：2011-12-01

申请号：US13207197

申请日：2011-08-10

Applicant: Alois FRIEDBERGER ,  Ulrich REIDT ,  Gerhard MÜLLER

Inventor： Alois FRIEDBERGER ,  Ulrich REIDT ,  Gerhard MÜLLER

IPC: C12Q1/70 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/569

CPC classification number: C12M1/3446 ,  C12Q1/6888 ,  G01N33/56911 ,  G01N33/56983

Abstract: A device for the detection of micro particles that can be marked by probes or antibodies capable of being detected by radiation has a filter, a supply system, and a detection system. Fluid to be examined is passed over a filter to filter out the micro particles and to perform the marking steps by supplying corresponding marking substances to the filter

Abstract translation: 用于检测可被能够被辐射检测的探针或抗体标记的微粒的装置具有过滤器，供给系统和检测系统。 要检查的流体通过过滤器以过滤出微粒子，并通过向过滤器提供相应的标记物质来执行标记步骤

公开(公告)号：US20110071037A1

公开(公告)日：2011-03-24

申请号：US12994420

申请日：2009-05-13

Applicant: Gerhard Müller ,  Andreas Helwig

Inventor： Gerhard Müller ,  Andreas Helwig

IPC: C40B30/00 ,  C12M1/34 ,  C40B60/12 ,  C12Q1/04

CPC classification number: G01N33/0026 ,  G01N1/2214

Abstract: The invention relates to a gas detection system (1) for detecting gases, vapors and biological pathogens, having at least one receptor (4) arranged on a line (5) connecting the ambient air (7) to an air storage unit, wherein the gas detection system (1) is designed as a “breathing” system containing clean CO2-carrying and moisture-saturated air in the air storage unit (2), wherein the operating temperature of the gas detection system (1) is the room temperature. Additionally, a method is proposed for detecting gases, vapors and biological pathogens using the inventive gas detection system. This avoids the shortcomings of the known solutions of the prior art, and an improved and more cost-effective solution for detecting trace gases is made available.

Abstract translation: 本发明涉及一种用于检测气体，蒸汽和生物病原体的气体检测系统（1），其具有布置在将周围空气（7）连接到空气存储单元的管线（5）上的至少一个接收器（4），其中 气体检测系统（1）被设计为在空气存储单元（2）中含有清洁的含CO 2和湿气的空气的“呼吸”系统，其中气体检测系统（1）的工作温度为室温。 另外，提出了使用本发明的气体检测系统来检测气体，蒸气和生物病原体的方法。 这避免了现有技术的已知解决方案的缺点，并且提供了用于检测痕量气体的改进且更具成本效益的解决方案。