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    Device for controlling particle distribution in an evaporating droplet using radial electroosmotic flow
    13.
    发明授权
    Device for controlling particle distribution in an evaporating droplet using radial electroosmotic flow 有权
    用于使用径向电渗流控制蒸发液滴中的颗粒分布的装置

    公开(公告)号：US08287707B2

    公开(公告)日：2012-10-16

    申请号：US11501124

    申请日：2006-08-08

    Applicant: Jeong-gun Lee ,  Sung-jae Kim

    Inventor： Jeong-gun Lee ,  Sung-jae Kim

    IPC: B01D57/00 ,  B01D15/00

    CPC classification number: C07K1/26

    Abstract: Provided is a device for controlling a particle distribution in a droplet including particles. The device includes: a first electrode for developing an electric field in the vicinity of the droplet; and a second electrode for developing the electric field that is fixed to a substrate, is insulated from the first electrode, and located at about the center of the droplet. A micro electrode system including a circular electrode placed along a droplet rim and a point electrode at about the center of the bottom is used to cause radial electroosmotic flow, thereby obtaining a uniform solute distribution after complete evaporation of the droplet. The direction and strength of the radial electroosmotic flow can be varied and the radial electroosmotic flow is periodically applied. Particles used to obtain uniformity are selected from the group consisting of a polymer, an organic substance, an inorganic substance, a metal, and a biomolecule. The particles can be neutral, negatively charged or positively charged.

    Abstract translation: 提供了一种用于控制包含颗粒的液滴中的颗粒分布的装置。 该装置包括：用于在液滴附近形成电场的第一电极; 并且用于显影固定到基板的电场的第二电极与第一电极绝缘，并且位于液滴的中心附近。 使用包括沿着液滴边缘放置的圆形电极和位于底部中心附近的点电极的微电极系统引起径向电渗流，从而在液滴完全蒸发之后获得均匀的溶质分布。 径向电渗流的方向和强度可以变化，并且周期性地施加径向电渗流。 用于获得均匀性的颗粒选自聚合物，有机物质，无机物质，金属和生物分子。 颗粒可以是中性的，带负电的或带正电的。

    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL
    16.
    发明申请
    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL 有权
    目标颗粒分离装置和使用多元流动分离通道的方法

    公开(公告)号：US20110303586A1

    公开(公告)日：2011-12-15

    申请号：US13156630

    申请日：2011-06-09

    Applicant: Tae-seok SIM ,  Jeong-gun LEE ,  Hyo-il JUNG ,  Ki-ho KWON

    Inventor： Tae-seok SIM ,  Jeong-gun LEE ,  Hyo-il JUNG ,  Ki-ho KWON

    IPC: B03B7/00 ,  B07B1/00

    CPC classification number: B01L3/502761 ,  B01L3/502753 ,  B01L2200/0652 ,  B01L2300/087 ,  B01L2400/0487

    Abstract: A device separating target particles in a fluid sample includes first through third multi-orifice flow fractionation (“MOFF”) channels, each including a multi-orifice segment with an inlet and an outlet at opposite ends, and an alternating series of contraction channels and expansion chambers interconnected in a lengthwise direction; a first separation unit including a first separation channel which is interconnected in fluid communication with a center region of the outlet of the first MOFF channel, and first branch channels which are interconnected in fluid communication with sidewall regions of the outlet of the first MOFF channel, and respectively with inlets of the second and third MOFF channels; and buffer inlets which are connected to the inlets of the second and third MOFF channels and through which a buffer flows into the second and third MOFF channels.

    Abstract translation: 分离流体样品中的目标颗粒的装置包括第一至第三多孔流动分馏（“MOFF”）通道，每个通道包括具有相对端的入口和出口的多孔段，以及交替的一系列收缩通道和 膨胀室沿长度方向互相连接; 第一分离单元，包括与第一MOFF通道的出口的中心区域流体连通的第一分离通道和与第一MOFF通道的出口的侧壁区域流体连通地互连的第一分支通道， 并分别具有第二和第三MOFF通道的入口; 以及连接到第二和第三MOFF通道的入口并且缓冲器通过其流入第二和第三MOFF通道的缓冲器入口。

    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP
    17.
    发明申请
    MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP 有权
    使用生物分子微量芯片的微流控芯片和微流化器件的微流体装置

    公开(公告)号：US20110257037A1

    公开(公告)日：2011-10-20

    申请号：US13168298

    申请日：2011-06-24

    Applicant: Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

    Inventor： Beom-seok LEE ,  Jeong-gun Lee ,  Jong-myeon Park ,  Yoon-kyoung Cho

    IPC: C40B40/00 ,  C40B40/10 ,  C40B40/02 ,  C40B40/06

    CPC classification number: B01L3/502738 ,  B01L3/502707 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/025 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/04 ,  B01L2300/0636 ,  B01L2300/0806 ,  B01L2400/0409 ,  B01L2400/0677 ,  Y10T436/15

    Abstract: Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.

    Abstract translation: 公开了一种微流体装置，其包括在平台中形成的微流体结构，其中可以使用生物分子微阵列芯片自动执行各种检查，例如免疫血清检查。 使用生物分子微阵列芯片的生物分子微阵列芯片型微流器件包括：可旋转的平台; 设置在平台中的微流体结构，包括：多个室; 连接所述室的多个通道; 以及多个阀，其控制通过所述通道的流体流动，其中所述微流体结构通过所述平台和所述阀的旋转来控制流体样品的流动; 以及安装在平台中的生物分子微阵列芯片，使得与生物分子微阵列芯片结合的生物分子捕获探针与微流体结构中的流体样品接触。

    Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve
    20.
    发明授权
    Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve 有权
    微流控阀，其制造方法以及包含微流体阀的微流体装置

    公开(公告)号：US07980272B2

    公开(公告)日：2011-07-19

    申请号：US12133396

    申请日：2008-06-05

    Applicant: Jong-myeon Park ,  Yoon-kyoung Cho ,  Beom-seok Lee ,  Jeong-gun Lee

    Inventor： Jong-myeon Park ,  Yoon-kyoung Cho ,  Beom-seok Lee ,  Jeong-gun Lee

    IPC: F15C1/04

    CPC classification number: F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0084 ,  Y10T29/49412 ,  Y10T137/2191 ,  Y10T137/2196

    Abstract: Provided is a microfluidic valve, a method of manufacturing the microfluidic valve, and a microfluidic device that employs the microfluidic valve. The microfluidic valve includes a platform that includes two substrates combined facing each other; a channel having a first depth allowing a fluid to flow between the two substrates; a valve gap that is disposed on at least a region of the channel and has a second depth which is smaller than the first depth; and a valve plug that is disposed to fill the valve gap and is formed of a valve material made by mixing a phase change material, which is solid at room temperature, with a plurality of exothermic particles that emit an amount of heat sufficient to melt the phase change material by absorbing electromagnetic waves.

    Abstract translation: 本发明提供一种微流体阀，微流体阀的制造方法和采用该微流体阀的微流体装置。 该微流体阀包括一个平台，该平台包括彼此相结合的两个基板; 具有允许流体在两个基板之间流动的第一深度的通道; 阀间隙，其设置在所述通道的至少一个区域上，并且具有小于所述第一深度的第二深度; 以及阀塞，其设置成填充阀间隙，并且由阀室材料形成，所述阀门材料是通过将在室温下为固体的相变材料与多个放出足以熔化的 相变材料吸收电磁波。

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