Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve
    12.
    发明授权
    Microfluidic valve, method of manufacturing the same, and microfluidic device comprising the microfluidic valve 有权
    微流控阀,其制造方法以及包含微流体阀的微流体装置

    公开(公告)号:US07980272B2

    公开(公告)日:2011-07-19

    申请号:US12133396

    申请日:2008-06-05

    IPC分类号: F15C1/04

    摘要: Provided is a microfluidic valve, a method of manufacturing the microfluidic valve, and a microfluidic device that employs the microfluidic valve. The microfluidic valve includes a platform that includes two substrates combined facing each other; a channel having a first depth allowing a fluid to flow between the two substrates; a valve gap that is disposed on at least a region of the channel and has a second depth which is smaller than the first depth; and a valve plug that is disposed to fill the valve gap and is formed of a valve material made by mixing a phase change material, which is solid at room temperature, with a plurality of exothermic particles that emit an amount of heat sufficient to melt the phase change material by absorbing electromagnetic waves.

    摘要翻译: 本发明提供一种微流体阀,微流体阀的制造方法和采用该微流体阀的微流体装置。 该微流体阀包括一个平台,该平台包括彼此相结合的两个基板; 具有允许流体在两个基板之间流动的第一深度的通道; 阀间隙,其设置在所述通道的至少一个区域上,并且具有小于所述第一深度的第二深度; 以及阀塞,其设置成填充阀间隙,并且由阀室材料形成,所述阀门材料是通过将在室温下为固体的相变材料与多个放出足以熔化的 相变材料吸收电磁波。

    PUMP UNIT AND CENTRIFUGAL MICROFLUIDIC SYSTEM HAVING THE SAME
    16.
    发明申请
    PUMP UNIT AND CENTRIFUGAL MICROFLUIDIC SYSTEM HAVING THE SAME 审中-公开
    泵单元和离心微流体系统

    公开(公告)号:US20080226504A1

    公开(公告)日:2008-09-18

    申请号:US11861324

    申请日:2007-09-26

    IPC分类号: B04B5/10

    摘要: Provided are a pump unit and a centrifugal microfluidic system including the pump unit. The pump unit includes a gas generating agent. The gas generating agent includes a plurality of heating particles generating heat by absorbing energy and one of a sublimation material, azide, and azo compound mixed with the heating particles. When energy is supplied to the gas generating agent, the gas generating agent generates gas due to heat emitted from the heating particles to increase an air pressure around the gas generation agent so that the fluid is moved by the increased air pressure.

    摘要翻译: 提供了包括泵单元的泵单元和离心微流体系统。 泵单元包括气体发生剂。 气体发生剂包括通过吸收能量产生热的多个加热颗粒和与加热颗粒混合的升华材料,叠氮化物和偶氮化合物之一。 当向气体发生剂供应能量时,气体发生剂由加热颗粒发出的热量产生气体,从而增加气体发生剂周围的空气压力,使得流体通过增加空气压力而移动。

    Method of and apparatus for the purification of nucleic acids using immobilized metal-ligand complex
    20.
    发明申请
    Method of and apparatus for the purification of nucleic acids using immobilized metal-ligand complex 审中-公开
    使用固定化金属 - 配体复合物纯化核酸的方法和设备

    公开(公告)号:US20060275815A1

    公开(公告)日:2006-12-07

    申请号:US11446795

    申请日:2006-06-05

    IPC分类号: C12Q1/68 C07H21/04

    CPC分类号: C07H21/04 C12N15/1006

    摘要: Provided is a method of purifying nucleic acids using a metal-ligand complex, the method comprising: immobilizing the metal-ligand complex on a solid support; bringing a sample containing the nucleic acid into contact with the immobilized complex on the solid support to bind the nucleic acid to the complex; and adding a solution containing a chelate capable of removing the metal to elute the nucleic acid bound to the complex. The nucleic acids can be efficiently purified using a metal-ligand complex interacting with a base of the nucleic acid instead of interacting with a phosphoric acid of the nucleic acid to selectively bind the nucleic acid, and using a chelator capable of removing the metal to elute the nucleic acid.

    摘要翻译: 提供了使用金属 - 配体络合物纯化核酸的方法,所述方法包括:将所述金属 - 配体复合物固定在固体支持物上; 使含有核酸的样品与固体支持物上的固定化复合物接触以将核酸结合到复合物上; 并加入含有能除去金属的螯合物的溶液以洗脱与络合物结合的核酸。 可以使用与核酸的碱基相互作用的金属 - 配体复合物来有效纯化核酸,而不是与核酸的磷酸相互作用以选择性地结合核酸,并且使用能够去除金属洗脱的螯合剂 核酸。