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113 条记录 (耗时 0.033 秒)

    INTEGRATED HEATER AND MAGNETIC SEPARATOR
    12.
    发明申请
    INTEGRATED HEATER AND MAGNETIC SEPARATOR 审中-公开

    公开(公告)号：US20190145546A1

    公开(公告)日：2019-05-16

    申请号：US16200356

    申请日：2018-11-26

    申请人： HandyLab, Inc.

    发明人： Kalyan Handique

    IPC分类号： F16K99/00 ,  B03C1/28 ,  B01L7/00 ,  B01L9/00

    摘要： An apparatus for providing thermal and magnetic energy to a receptacle containing a reaction mixture and a magnetic retention member. The apparatus can also control heating of a reaction mixture, and bring about a separation of magnetic particles from the reaction mixture. The reaction mixture typically comprises polynucleotides from a biological sample that are being brought into a PCR-ready form.

    MICROFLUIDIC CARTRIDGE
    13.
    发明申请
    MICROFLUIDIC CARTRIDGE 审中-公开

    公开(公告)号：US20190054467A1

    公开(公告)日：2019-02-21

    申请号：US16119812

    申请日：2018-08-31

    申请人： HandyLab, Inc.

    发明人： Kalyan Handique

    IPC分类号： B01L3/00 ,  B01L7/00 ,  F16K99/00

    摘要： The technology described herein generally relates to microfluidic cartridges configured to amplify and detect polynucleotides extracted from multiple biological samples in parallel. The technology includes a microfluidic substrate, comprising: a plurality of sample lanes, wherein each of the plurality of sample lanes comprises a microfluidic network having, in fluid communication with one another: an inlet; a first valve and a second valve; a first channel leading from the inlet, via the first valve, to a reaction chamber; and a second channel leading from the reaction chamber, via the second valve, to a vent.

    MULTIPLEXED DIAGNOSTIC DETECTION APPARATUS AND METHODS
    16.
    发明申请
    MULTIPLEXED DIAGNOSTIC DETECTION APPARATUS AND METHODS 审中-公开
    多重诊断检测装置及方法

    公开(公告)号：US20140329301A1

    公开(公告)日：2014-11-06

    申请号：US14267232

    申请日：2014-05-01

    申请人： Handylab, Inc.

    发明人： Kalyan Handique

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6806 ,  B01L3/5027 ,  B01L3/502723 ,  B01L3/502738 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2400/06 ,  B01L2400/0677 ,  F16K99/0036 ,  F16K2099/0084

    摘要： Disclosed herein are devices configured for the amplification and detection of multiple targets from a sample, and methods of using the same. The devices disclosed herein comprise microfluidic cartridges have a first stage (amplification) and a second (detection) stage. The two-stage design of the cartridges enables testing for multiple targets within a sample, i.e., from a single nucleic acid amplification reaction. Methods for the amplification and detection of a plurality of target nucleic acids from a sample are also disclosed herein.

    摘要翻译： 这里公开了被配置用于从样品中放大和检测多个靶的装置及其使用方法。 本文公开的装置包括具有第一阶段（放大）和第二（检测）阶段的微流体盒。 盒的两级设计使得能够测试样品内的多个靶，即来自单个核酸扩增反应。 本文还公开了用于从样品扩增和检测多种靶核酸的方法。