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公开(公告)号:US20050112676A1
公开(公告)日:2005-05-26
申请号:US10993432
申请日:2004-11-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
摘要翻译: 本发明提供了用于测序,指纹和绘制生物大分子(通常为生物聚合物)的方法和装置。 该方法利用多种序列特异性识别试剂,其也可用于生物样品的分类和表征其来源。
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公开(公告)号:US20050053928A9
公开(公告)日:2005-03-10
申请号:US10125530
申请日:2002-04-19
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
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公开(公告)号:US20050009014A9
公开(公告)日:2005-01-13
申请号:US10102774
申请日:2002-03-22
申请人: Stephen Fodor , Dennis Solas , William Dower
发明人: Stephen Fodor , Dennis Solas , William Dower
IPC分类号: B01J19/00 , C07B61/00 , C07H19/10 , C07H21/00 , C07K1/04 , C07K17/06 , C07K17/14 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/14 , G03F7/00 , G03F7/26 , G03F7/38 , G11C13/02 , C12M1/34 , G01N33/53 , G01N33/542
CPC分类号: G03F7/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00641 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07H19/10 , C07H21/00 , C07K1/042 , C07K1/045 , C07K17/06 , C07K17/14 , C12Q1/6804 , C12Q1/6809 , C12Q1/6816 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , G01N15/1475 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , C12Q2565/513 , C12Q2565/507 , C12Q2545/101 , C12Q2525/185 , C12Q2565/514 , C12Q2563/173 , C12Q2563/119 , C12Q2563/149 , C12Q2525/151 , C12Q2525/179 , C12Q2525/204
摘要: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
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公开(公告)号:US20060210452A1
公开(公告)日:2006-09-21
申请号:US11212551
申请日:2005-08-25
IPC分类号: B01J19/00
CPC分类号: C08G69/00 , B01J19/0046 , B01J2219/00315 , B01J2219/00432 , B01J2219/00434 , B01J2219/00436 , B01J2219/00459 , B01J2219/00468 , B01J2219/00475 , B01J2219/005 , B01J2219/00527 , B01J2219/00529 , B01J2219/00531 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00619 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00639 , B01J2219/00648 , B01J2219/00659 , B01J2219/00689 , B01J2219/00695 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L7/52 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07C229/14 , C07C229/16 , C07D263/44 , C07D317/62 , C07H19/04 , C07H19/10 , C07H21/00 , C07K1/04 , C07K1/042 , C07K1/045 , C07K1/047 , C07K1/062 , C07K7/06 , C07K17/06 , C07K17/14 , C12Q1/6809 , C12Q1/6816 , C12Q1/6837 , C12Q1/6874 , C40B40/06 , C40B40/10 , C40B60/14 , C40B80/00 , G01N15/1475 , G01N21/253 , G01N21/6428 , G01N21/6452 , G03F7/00 , G03F7/26 , G03F7/265 , G03F7/38 , G11C13/0014 , G11C13/0019 , H01L25/50 , H01L2924/0002 , Y02P20/55 , Y10S435/961 , Y10S435/968 , Y10S435/969 , Y10S435/973 , Y10S436/807 , Y10S436/809 , Y10T428/31971 , Y10T436/2575 , H01L2924/00
摘要: A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protective groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
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