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公开(公告)号：US09020591B2
公开(公告)日：2015-04-28
申请号：US14100998
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, Jr. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61N1/18 , A61N7/00 , A61B5/11 , A61B5/00 , A61M5/142 , A61M5/172 , A61M35/00 , A61N1/04 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/145 , A61F7/00 , A61M5/168 , A61M37/00 , A61N1/30 , A61N1/32 , A61N1/36 , A61N1/372 , A61N2/00
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with ultrasound are disclosed. In an aspect, neural activity is blocked cyclically with an ultrasonic blocking stimulus source positioned adjacent a skin surface in a vicinity of a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过用超声周期性阻断外周神经结构传导来调节神经活动的方法和相关系统。 在一个方面，神经活动被周期性阻挡，超声阻断刺激源位于神经附近的皮肤表面附近。 在一方面，在感觉神经中产生传导阻滞。 神经调节可用于例如调节免疫或炎症反应或过程。
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公开(公告)号：US08670633B2
公开(公告)日：2014-03-11
申请号：US13645359
申请日：2012-10-04
Applicant: Searete LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC classification number: G06T5/006 , G06T2207/30012
Abstract: Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.
Abstract translation: 某些方面可以涉及响应于至少一些输入补偿信息，以至少限制与至少一个失真特征相关联的至少一个失真特征的至少一部分的至少一些失真效应的方式成像该个体的至少一部分 所述个体的至少一部分至少部分地通过当应用于与所述个体的至少一部分相关联的所述至少一个失真特征的所述至少一部分时，从成像模态修改非光学电磁输出。 某些方面可以涉及产生非光学电磁输出的至少一个共形缺失，以将失真限制到个体的至少一部分的成像，至少部分地由至少一个与至少部分相关联的变形特征 的个人。
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13.发明申请SYSTEM, DEVICES, AND METHODS INCLUDING STERILIZING EXCITATION DELIVERY IMPLANTS WITH GENERAL CONTROLLERS AND ONBOARD POWER 审中-公开系统，设备和方法，包括用一般控制器和ONBOARD功率灭菌激活输送植入物公开(公告)号：US20140039357A1
公开(公告)日：2014-02-06
申请号：US14046577
申请日：2013-10-04
Applicant: Searete LLC
Inventor： Edward S. Boyden , Ralph G. Dacey, JR. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kara , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC: A61L2/00
CPC classification number: A61L2/0011 , A61L2/0023 , A61L2/0052
Abstract: Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
Abstract translation: 描述了用于提供主动控制的消毒可植入装置的系统，装置，方法和组合物，其被配置为例如治疗或预防生物学对象中的感染。
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14.发明申请SYSTEMS AND METHODS FOR AUTOMATICALLY INSERTING A NEEDLE INTO A LIVING SUBJECT 审中-公开将针头自动插入生活用品的系统和方法公开(公告)号：US20130041253A1
公开(公告)日：2013-02-14
申请号：US13648752
申请日：2012-10-10
Applicant: SEARETE LLC
Inventor： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Michael A. Smith , Leif T. Stordal , Lowell L. Wood, Jr. , Victoria Y.H. Wood
IPC: A61B6/12
CPC classification number: A61M5/3287 , A61B5/150022 , A61B5/15003 , A61B5/150106 , A61B5/150167 , A61B5/150229 , A61B5/150748 , A61B5/15087 , A61B5/15109 , A61B5/15117 , A61B5/15121 , A61B5/15123 , A61B5/15125 , A61B5/153 , A61B6/00 , A61B10/0283 , A61B17/3403 , A61B34/30 , A61B90/11 , A61B90/361 , A61B2017/00199 , A61B2017/00398 , A61B2017/00402 , A61B2017/00539 , A61B2017/00544 , A61B2017/3409 , A61B2090/376 , A61B2090/378 , A61M5/427 , A61M2005/14252 , A61M2005/1585 , A61M2205/59
Abstract: Embodiments disclosed herein are directed to systems and methods for automatically inserting a needle into an insertion-target region of a living subject in response to a machine-vision system locating the insertion-target region. In an embodiment, a needle insertion system includes a moveable needle configured to be inserted into a living subject, a machine-vision system configured to locate an insertion-target region of the living subject, control electrical circuitry, and an actuator coupled to the control electrical circuitry. The control electrical circuitry may be coupled to the machine-vision system to receive location information therefrom about the insertion-target region, and configured to output needle targeting instructions. The actuator may be coupled to the control electrical circuitry to receive the needle targeting instructions therefrom and coupled to the moveable needle. The actuator may be configured to move the moveable needle to the insertion-target region automatically in response to receiving the needle targeting instructions from the control electrical circuitry.
Abstract translation: 本文公开的实施例涉及用于响应于定位插入目标区域的机器视觉系统而自动将针插入活体的插入目标区域的系统和方法。 在一个实施例中，针插入系统包括构造成插入生物体的可移动针，被配置为定位活体的插入目标区域，控制电路和耦合到控制器的致动器的机器视觉系统 电路。 控制电路可以耦合到机器视觉系统以从其接收关于插入目标区域的位置信息，并且被配置为输出针瞄准指令。 致动器可以联接到控制电路以从其接收针头指令并且联接到可移动的针。 致动器可以被配置为响应于接收到来自控制电路的针瞄准指令而自动地将可移动针移动到插入目标区域。
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公开(公告)号：US20130034288A1
公开(公告)日：2013-02-07
申请号：US13645359
申请日：2012-10-04
Applicant: SEARETE LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K.Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y.H. Wood
IPC: G06K9/40
CPC classification number: G06T5/006 , G06T2207/30012
Abstract: Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.
Abstract translation: 某些方面可以涉及响应于至少一些输入补偿信息，以至少限制与至少一个失真特征相关联的至少一个失真特征的至少一部分的至少一些失真效应的方式成像该个体的至少一部分 所述个体的至少一部分至少部分地通过当应用于与所述个体的至少一部分相关联的所述至少一个失真特征的所述至少一部分时，从成像模态修改非光学电磁输出。 某些方面可以涉及产生非光学电磁输出的至少一个共形缺失，以将失真限制到个体的至少一部分的成像，至少部分地由至少一个与至少部分相关联的变形特征 的个人。
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Patent Agency Ranking
公开(公告)号：US20160027147A1
公开(公告)日：2016-01-28
申请号：US14788455
申请日：2015-06-30
Applicant: SEARETE LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Thomas A. Weaver , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC classification number: G06T3/0075 , G06K2209/05 , G06T3/0006 , G06T7/0012 , G06T7/33 , G06T2200/04 , G06T2207/10072 , G06T2207/30016 , G06T2207/30048 , G06T2207/30061 , G06T2207/30101
Abstract: A method may include processing two or more fiducials included in a three-dimensional medical image and included in a current image to generate two or more transform coefficients of a transform, and applying the transform to the three-dimensional medical image to form a present image.
Abstract translation: 一种方法可以包括处理包括在三维医学图像中并包括在当前图像中的两个或更多个基准以产生变换的两个或更多个变换系数，并且将该变换应用于三维医学图像以形成当前图像 。
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公开(公告)号：US20150283365A1
公开(公告)日：2015-10-08
申请号：US14683198
申请日：2015-04-10
Applicant: Searete LLC
Inventor： Ralph G. Dacey, JR. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, JR. , Victoria Y.H. Wood , Gregory J. Zipfel
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures are disclosed. Neural activity may blocked cyclically by blocking stimuli delivered via various types of blocking stimulus sources. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an undesired sensation, such as pain, or an immune or inflammatory response or process. Delivery of blocking stimuli may be controlled in part in response to an input from a user input device.
Abstract translation: 公开了通过循环阻断外周神经结构传导来调节神经活动的方法和相关系统。 通过阻断通过各种类型的阻断刺激源递送的刺激，神经活动可能会周期性阻断。 在一方面，在感觉神经中产生传导阻滞。 例如，可以使用神经调节来调节不期望的感觉，例如疼痛，或免疫或炎症反应或过程。 可以部分地响应于来自用户输入设备的输入来控制传递阻塞刺激。
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公开(公告)号：US20140163647A1
公开(公告)日：2014-06-12
申请号：US14101022
申请日：2013-12-09
Applicant: Searete LLC
Inventor： Ralph G. Dacey, JR. , Gregory J. Della Rocca , Colin P. Derdeyn , Joshua L. Dowling , Eleanor V. Goodall , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Michael A. Smith , Lowell L. Wood, JR. , Victoria Y. H. Wood , Gregory J. Zipfel
IPC: A61N1/36
CPC classification number: A61M5/14276 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/1118 , A61B5/14539 , A61B5/4035 , A61B5/4041 , A61B5/411 , A61B5/441 , A61B5/4821 , A61B5/4839 , A61F7/00 , A61F7/0085 , A61F2007/0075 , A61M5/14244 , A61M5/14248 , A61M5/16827 , A61M5/1723 , A61M35/00 , A61M37/00 , A61M37/0015 , A61M37/0092 , A61M2005/14208 , A61M2005/1726 , A61M2037/0007 , A61M2205/0244 , A61M2210/1003 , A61N1/0412 , A61N1/0428 , A61N1/30 , A61N1/303 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36103 , A61N1/36135 , A61N1/37252 , A61N2/002 , A61N2/006 , A61N7/00 , A61N2007/0026
Abstract: Methods and related systems for modulating neural activity by cyclical blocking of conduction in peripheral neural structures with electrical blocking stimuli are disclosed. In an aspect, neural activity is blocked cyclically with an electrical blocking stimulus source implanted adjacent a nerve. In an aspect, a conduction block is produced in a sensory nerve. Neural modulation may be used, for example, to modulate an immune or inflammatory response or process.
Abstract translation: 公开了通过具有电阻塞刺激的周围神经结构中的传导的循环阻断来调节神经活动的方法和相关系统。 在一个方面，神经活动被循环地阻挡，其中植入邻近神经的电阻塞刺激源。 在一方面，在感觉神经中产生传导阻滞。 神经调节可用于例如调节免疫或炎症反应或过程。
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公开(公告)号：US20130248580A1
公开(公告)日：2013-09-26
申请号：US13901888
申请日：2013-05-24
Applicant: Searete LLC
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, JR. , Victoria Y.H. Wood
IPC: A61B17/068
CPC classification number: A61B17/068 , A61B17/00491 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/00022 , A61B2017/00221 , A61B2017/00398 , A61B2017/00402 , A61B2017/00871 , A61B2017/07214 , A61B2017/07278 , A61B2017/2905
Abstract: Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.
Abstract translation: 实施例包括手术装置和方法。 手术器械的一个实施例包括至少一个抓持爪，所述至少一个抓持爪适于通过由容纳在所述至少一个抓持爪内的力产生器机构产生的力来输送外科缝合钉，或者靠近 所述至少一个抓握爪。 另一个实施例包括至少一个抓持爪，至少一个致动机构，其适于递送手术紧固件，所述致动机构位于所述至少一个抓持爪附近或者包含在所述至少一个抓持爪内，所述手术紧固件包含至少一个形状转换材料 ，至少一个传感器，至少一个化学组织密封剂和至少一个切割器。 一种方法包括：用至少一个抓持爪抓住身体器官/组织，响应于信号或基准面或图像调节抓握的构型，以及响应于信号，基准或释放手术钉/紧固件 图片。
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20.发明申请SYSTEMS, DEVICES, AND METHODS INCLUDING INFECTION-FIGHTING AND MONITORING SHUNTS 有权系统，设备和方法，包括感染和监测公开(公告)号：US20130131575A1
公开(公告)日：2013-05-23
申请号：US13715296
申请日：2012-12-14
Applicant: Searete LLC
Inventor： Ralph G. Dacey, JR. , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, JR. , Victoria Y.H. Wood
CPC classification number: A61N5/0601 , A61B5/0084 , A61B5/053 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/412 , A61B18/20 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2202/24 , A61M5/14276 , A61M27/006 , A61N1/205 , A61N1/37252 , A61N1/3785 , A61N1/3787 , A61N1/40 , A61N1/403 , A61N5/02 , A61N5/0624 , A61N5/10 , A61N7/00 , A61N2005/0651 , A61N2005/0652 , A61N2005/0661
Abstract: Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
Abstract translation: 描述了用于提供被配置为例如监视，治疗或预防感染的主动控制分路的系统，装置，方法和组合物。
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