Abstract:
A micro integrated analysis system includes a testing chip, system main body and heat insulating section. The chip has a pump connecting section to communicate with micro pumps; a mixing flow path for mixing a specimen and reagent and for reaction processing by heating; and a testing flow path for performing a predetermined test of a mixed solution heated and processed for reaction. The system main body has a holding section to hold the testing chip; micro pumps for injecting a specimen and reagent; a heating section for heating the mixing flow path; and a detection section for performing a test in the testing flow path. The heat insulating section insulates flow path portions continuing from both an inlet end and outlet end of a heated flow path area of the mixing flow path, from heat of the heating section so as to prevent a rise in temperature.
Abstract:
A testing microchip includes a specimen storage section; a reagent storage section; a reaction section; a testing section for a test of a reaction product obtained from the reaction; a liquid feed control section; and a gas bubble trapping structure. The sections are connected continuously by a series of flow channels. The liquid feed control section stops passing of liquid until a liquid feeding pressure reaches a predetermined pressure, and passes the liquid when the liquid feeding pressure becomes higher than the predetermined pressure; and the gas bubble trapping structure traps a gas bubble in the liquid that flows in the flow channel so that the gas bubble does not flow to the downstream side and only the liquid passes to the downstream side. A testing apparatus that performs testing in the testing section of the testing microchip, wherein the testing microchip is attachably and detachably mounted to the apparatus.
Abstract:
A micro total analysis system, comprising: an examination chip provided with a micro flow path and a flow path opening section communicating with a micropump on the upstream side of a reagent containing section, a drive fluid tank containing drive fluid, a micropump unit provided with a plurality of the micropumps such that the upstream side of each micropump communicates with the drive fluid tank and a flow path opening communicating with the micro flow path of the examination chip is provided on the downstream side, and a system body including the micropump unit and the drive fluid tank in one storing body, wherein analysis is performed while the examination chip is attached to the system body, and a mechanism for altering the direction of pressure at the flow path opening of the micropump unit depending on attaching/detaching of the examination chip to/from the system main body is provided.
Abstract:
A microchip having: two flow path substrates having flow paths in a shape of a groove formed on one side of each substrate thereof; and a communication hole substrate on which a communication hole is formed to communicate the flow paths of the two substrates each other; wherein the two substrates are bonded in a way that the surfaces, on which the flow paths in the shape of the groove formed, face each other, having the communication hole substrate therebetween.
Abstract:
A method and a device are provided which can mix two liquids faster at a precise mixing ratio. The method for mixing at least two liquids transported in respective channels includes transporting, of the two liquids, a liquid having a low mixing rate intermittently in one of the channels, and transporting, of the two liquids, a liquid having a high mixing rate so as to join the liquid having a low mixing rate from both sides of the channel for the liquid having a low mixing rate.
Abstract:
A system including an inspection chip equipped with at least a pump connection having a flow path opening for interconnecting to a micro-pump, a flow path through which a fluid flows, and a fluid mixing section for joining and mixing two or more fluids, and including a system body equipped with at least a base body, a chip connection having a flow path opening for interconnecting to the inspection chip, a micro-pump unit in the base body including micro-pumps in substantially the same shape, a detection processor and a controller for controlling at least the functions of the micro-pump unit and the detection processor, and the joining amount ratio is adjusted to set the mixing ratio of two fluids to be joined in the fluid mixing section to be approximately m:n (not 1:1) by making the drive voltages of the micro-pumps substantially equal to each other.
Abstract:
A micro integrated analysis system includes a testing chip, system main body and heat insulating section. The chip has a pump connecting section to communicate with micro pumps; a mixing flow path for mixing a specimen and reagent and for reaction processing by heating; and a testing flow path for performing a predetermined test of a mixed solution heated and processed for reaction. The system main body has a holding section to hold the testing chip; micro pumps for injecting a specimen and reagent; a heating section for heating the mixing flow path; and a detection section for performing a test in the testing flow path. The heat insulating section insulates flow path portions continuing from both an inlet end and outlet end of a heated flow path area of the mixing flow path, from heat of the heating section so as to prevent a rise in temperature.
Abstract:
A micro reactor for inspecting a biological material, comprising: a first substrate on which a minute flow path is formed; a second substrate laminated on the first substrate so as to cover the minute flow path; a detection section provided on the minute flow path formed between the first and second substrates so as to inspect a liquid mixture of a sample and a reagent; (4) an opening section formed at a region on the second substrate corresponding to the detection section so as to irradiate inspection light to the liquid mixture arriving the detection; and (5) a transparent member to cover the opening section.
Abstract:
A microfluidic device for performing a test on the reagent includes a fill port formed on the chip to inject the reagent into at least one of the channels, one or more heating portions for performing a test on the reagent injected into the channel, and a micropump. An inside of the micropump and a vicinity of the channel connecting to an inlet and an outlet of the micropump are filled with a drive solution that is driven by the micropump, a gas is sealed between the reagent and the drive solution in the channel to prevent the reagent from contacting the drive solution directly, and the micropump directly drives the drive solution in the forward and backward directions, so that the reagent is repeatedly moved to the test portions through the gas in an indirect manner or is repeatedly passed through the test portions through the gas.
Abstract:
A micro-reactor for analyzing a sample, comprises (1) a plate-shaped chip; (2) a plurality of regent storage sections each having a chamber to store respective agents; (3) a regent mixing section to mix plural regents fed from the plurality of regent storage sections so as to produce a mixed reagent; (4) a sample receiving section having an injection port through which a sample is injected from outside; and (5) a reacting section to mix and react the mixed regent fed from the reagent mixing section and the sample fed from the sample receiving section. The plurality of regent storage sections, the regent mixing section, the sample receiving section and the reacting section are incorporated in the chip and are connected through flow paths, and the regent mixing section includes a feed-out preventing mechanism to prevent an initially-mixed regent from being fed out to the reacting section.