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公开(公告)号：US20210393496A1
公开(公告)日：2021-12-23
申请号：US17284643
申请日：2019-10-10
Applicant: AMOREPACIFIC CORPORATION
Inventor： Eun Jeong CHOI , Young Gyu KANG , Jihyun KIM , Euidong SON , Gayoung CHO , Sowoong CHOI , Hyoung June KIM , Tae Ryong LEE
Abstract: Provided are a composition including coumestrol extracted from soybeans as an active ingredient, and a method of inhibiting cortisone reductase by applying it to skin of a subject.
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公开(公告)号：US20200261351A1
公开(公告)日：2020-08-20
申请号：US16651878
申请日：2018-08-23
Applicant: AMOREPACIFIC CORPORATION
Inventor： Hyoung-June KIM , Kyeonghwan HWANG , Jun Seong PARK , Tae Ryong LEE
IPC: A61K8/9789 , A61K36/82 , A23L33/105 , A61Q19/08
Abstract: The present specification discloses a composition for caring for skin damage caused by fine dust, wherein the composition includes a fermented tea extract as an active ingredient and adjusts the expression level of at least one selected from the following group of genes which are present in skin cells and have expression levels that are affected by fine dust to normal levels, said group consisting of: IL-1B (NM_000576), IL-36G (NM_019618), S100A7 (NM_002963), LCE3D (NM_032563), PTGS2 (NM_000963) and XDH (NM_000379). Damage to skin cells can be cared for by using the composition for caring for skin damage caused by fine dust to return gene expression levels, which change due to fine dust, to normal levels.
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公开(公告)号：US20190041383A1
公开(公告)日：2019-02-07
申请号：US15764615
申请日：2016-09-29
Applicant: AMOREPACIFIC CORPORATION
Inventor： Suh-Yeon CHOI , Eunkyung LEE , Eun-Gyung CHO , Tae Ryong LEE
Abstract: Disclosed in the present specification are a method for preparing senescent melanocytes, senescent cells prepared by the preparation method and a method for screening a senescence-alleviating or skin whitening material by using the senescent cells. The cells can be used for studying a cell senescence phenomenon and a pigmentation mechanism, which are caused by the accumulation of UV ray stimulation. Particularly, the cells are useful since a material having both senescence-alleviating and skin whitening effects can be screened.
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24.发明申请公开(公告)号：US20180044734A1
公开(公告)日：2018-02-15
申请号：US15554886
申请日：2016-04-04
Applicant: AMOREPACIFIC CORPORATION
Inventor： Hyoung-June KIM , Na Ri CHA , Ju Yearl PARK , Changjo JUNG , Lee-Kyoung KWON , Dong Wook SHIN , Tae Ryong LEE
CPC classification number: C12Q1/6883 , A23L33/10 , A23L33/30 , A23V2002/00 , A61K8/498 , A61K31/352 , A61Q19/00 , A61Q19/10 , C12Q2600/136 , C12Q2600/158 , G01N33/6893 , G01N2500/00 , G01N2800/20
Abstract: The present specification discloses a biomarker for diagnosing skin cell damage caused by fine dust, a kit using the same, and a novel use of a composition comprising galangin as an active ingredient. Specifically, it is possible to conveniently check skin damage caused by fine dust by measuring and comparing the expression amounts of the biomarker in normal cells and cells damaged by fine dust. In addition, a composition of the present invention comprising galangin, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof or a solvate thereof as an active ingredient can normalize the gene expression of skin damaged by fine dust and promote differentiation of skin keratinocytes, thereby having a skin moisturizing or skin-barrier strengthening effect. Accordingly, since the composition can be used to prevent, treat, or alleviate skin diseases such as atopy, psoriasis, etc. the composition is useful.
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公开(公告)号：US20170181796A1
公开(公告)日：2017-06-29
申请号：US15304993
申请日：2015-04-28
Applicant: AMOREPACIFIC CORPORATION
Inventor： Min Sik CHOI , Hyoung June KIM , Ji Yong JUNG , Tae Ryong LEE , Dong Wook SHIN
CPC classification number: A61B18/22 , A61B18/20 , A61B18/203 , A61B2018/00273 , A61B2018/00464 , A61B2018/2005 , A61N5/0601 , A61N5/0613 , A61N5/0616 , A61N2005/0612 , A61N2005/0643 , A61N2005/0659 , A61N2005/0662
Abstract: This specification provides a light source radiation apparatus for radiating light, a kit for lipolysis having a manual describing a method for dissolving fat by radiating light, and a slimming method for radiating light to skin. According to the specification, the present invention can dissolve neutral fat in a fat cell by radiating light of a wavelength in a range of light harmless to the body, thus can safely and effectively dissolve fat, and can be used for the slimming method by having the advantage of being more economical and convenient than a conventional lipolysis method.
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Patent Agency Ranking
公开(公告)号：US20170143617A1
公开(公告)日：2017-05-25
申请号：US15323198
申请日：2015-06-26
Applicant: AMOREPACIFIC CORPORATION
Inventor： Pil Joon PARK , So Hee LEE , Eun Gyung CHO , Tae Ryong LEE
CPC classification number: A61K8/97 , A23L2/52 , A23L33/105 , A23V2002/00 , A61K8/0204 , A61K8/0216 , A61K8/11 , A61K36/536 , A61K36/539 , A61K2800/782 , A61K2800/91 , A61K2800/92 , A61Q19/02
Abstract: The present specification discloses a composition comprising a Scutellaria alpina extract as an active ingredient. The composition disclosed in the present specification exhibits the effect of reducing melanogenesis or inhibiting tyrosinase activity by comprising the Scutellaria alpina extract. As a result of the effect, the Scutellaria alpina extract of the present specification can exhibit a whitening effect and thus can be widely used as a whitening composition in the field of pharmaceuticals or cosmetics.
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公开(公告)号：US20170114326A1
公开(公告)日：2017-04-27
申请号：US15402060
申请日：2017-01-09
Applicant: AMOREPACIFIC CORPORATION
Inventor： Joong Hyun SHIM , Seung Ha YANG , Tae Ryong LEE , Hak Hee KANG , Dong Wook SHIN
IPC: C12N5/0775 , C12Q1/68 , G01N33/74 , C12N5/071
CPC classification number: C12N5/0668 , A61K35/28 , A61K35/32 , A61K35/35 , A61K35/36 , C12N5/0625 , C12N2533/54 , C12Q1/6881 , C12Q2600/158 , G01N33/74 , G01N2333/475 , G01N2333/485 , G01N2333/49 , G01N2333/50
Abstract: Provided in the present invention are adult stem cells derived from human skin dermis, and a method for isolating same. Further provided in the present invention are osteoblastic cells and adipocytes differentiated from the adult stem cells derived from human skin dermis, and a differentiation method therefor. Further provided in the present invention is a composition for osteogenesis or lipogenesis containing the stem cells, osteoblastic cells, or adipocytes. The isolation method of the present invention enables the adult stem cells derived from human skin dermis to be obtained in an easy and simple manner at a high yield rate. Genes and growth factors which are specifically expressed in the adult stem cells derived from human skin dermis isolated using the method can be separated, identified, and used later.
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公开(公告)号：US20170035828A1
公开(公告)日：2017-02-09
申请号：US15305433
申请日：2015-04-29
Applicant: AMOREPACIFIC CORPORATION
Inventor： Pil Joon PARK , So Hee LEE , Eun Gyung CHO , Tae Ryong LEE
IPC: A61K36/539 , A61Q19/00 , A61K8/97
CPC classification number: A61K36/539 , A61K8/97 , A61K2800/74 , A61Q19/00 , A61Q19/08
Abstract: The present invention relates to a composition containing a Scutellaria alpina extract as an active ingredient. The composition of the present invention exhibits effects of reducing the amount of endothelin 1 by containing a Scutellaria alpina extract, and reducing the overexpression of NK1R and EDN1 genes. Therefore, the Scutellaria alpina extract of the present invention can exhibit, by said effects, skin homeostasis maintenance and anti-stress effects, and thus can be widely used as a composition for maintaining skin homeostasis in the pharmaceutical or cosmetic field.
Abstract translation: 本发明涉及含有黄芩提取物作为活性成分的组合物。 本发明的组合物显示出通过含有黄芩提取物来减少内皮素1的量并降低NK1R和EDN1基因的过表达的效果。 因此，本发明的黄芩提取物可以通过所述效果显示皮肤稳态维持和抗应激作用，因此可广泛用作药物或美容领域中用于维持皮肤稳态的组合物。
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公开(公告)号：US20230302769A1
公开(公告)日：2023-09-28
申请号：US17910715
申请日：2021-03-12
Applicant: Amorepacific Corporation
Inventor： Jeong Eun SEO , Hyun Hyub KO , JinYoung MYOUNG , Jong Hwa PARK , Young Oh LEE , Young Kyung KIM , Seung Han PARK , Won Seok PARK , Sung Won YI , Tae Ryong LEE , Byung Guen CHAE
CPC classification number: B32B9/045 , G01K7/183 , B32B27/304 , B32B27/283 , B32B27/18 , B32B2250/03 , B32B2307/20 , B32B2457/00
Abstract: A sensor for measuring a temperature change amount. The sensor includes a first composite material layer including a polymer having a volume changing according to a temperature change amount; an electrode layer provided on one side of the first composite material layer and capable of representing the temperature change amount as a resistance change amount; and a second composite material layer at least partially provided on the upper side of the first composite material layer and containing polydimethylsiloxane (PDMS) and at least one of carbon nanotubes (CNT), boron nitride nanotubes (BNNT), and graphene or containing a thermoplastic polyurethane (TPU) so that the temperature change occurring on one side thereof is transferred to the other side thereof.
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30.发明申请公开(公告)号：US20220000816A1
公开(公告)日：2022-01-06
申请号：US17285750
申请日：2019-10-15
Applicant: AMOREPACIFIC CORPORATION
Inventor： Eun Jeong CHOI , Euidong SON , Young Gyu KANG , Hyoung June KIM , Tae Ryong LEE
IPC: A61K31/192 , A61K9/00 , A61K36/15
Abstract: Provided are a composition including a compound of the following chemical formula as an active ingredient and a method of inhibiting a cortisone reductase by applying the same:
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