公开(公告)号：US20080045954A1

公开(公告)日：2008-02-21

申请号：US11831870

申请日：2007-07-31

Applicant: Mark REILEY ,  Robert Scribner ,  James Davidson

Inventor： Mark REILEY ,  Robert Scribner ,  James Davidson

IPC: A61B17/58

CPC classification number: A61F2/4405 ,  A61B17/7064 ,  A61B17/86 ,  A61F2/28 ,  A61F2002/30387 ,  A61F2002/30433 ,  A61F2002/305 ,  A61F2002/30537 ,  A61F2002/30604 ,  A61F2002/30777 ,  A61F2002/30874 ,  A61F2002/449 ,  A61F2002/4631 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2250/0004 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00131 ,  A61F2310/00179 ,  A61F2310/00329 ,  A61F2310/00604 ,  A61F2310/00634 ,  A61F2310/0097 ,  A61F2310/00976 ,  Y10S606/907 ,  Y10S606/91

Abstract: Cephalad and caudal vertebral facet joint prostheses and methods of use are provided. The prostheses provide an artificial facet joint structure including an artificial articular configuration unlike the preexisting articular configuration. The radii and material stress values of the prostheses are configured to sustain contact stress. The cephalad prosthesis provides for posterior-anterior adjustment. Both prostheses permit lateral adjustment and adjustment to accommodate interpedicle distance. Further, the prostheses may be customized to provide a pre-defined lordotic angle and a pre-defined pedicle entry angle.

Abstract translation: 提供头颅和尾椎椎骨小关节假体和使用方法。 所述假体提供与预先存在的关节构造不同的人造关节构造，其包括人造关节构造。 假体的半径和材料应力值被配置为维持接触应力。 头部假体提供前后调整。 两个假体允许横向调整和调节以适应插入距离。 此外，假体可以被定制以提供预定义的脊柱前凸角度和预定义的椎弓根进入角度。

公开(公告)号：US20070168355A1

公开(公告)日：2007-07-19

申请号：US11562287

申请日：2006-11-21

Applicant: Linda Dozier ,  George Williams ,  Dave Long ,  Douglas McKee ,  James Davidson ,  Karen Brady

Inventor： Linda Dozier ,  George Williams ,  Dave Long ,  Douglas McKee ,  James Davidson ,  Karen Brady

IPC: G06F17/30

CPC classification number: G06F16/10 ,  G06F16/958

Abstract: The present invention addresses the critical needs of publishers seeking to create and publish hypermedia content in electronic form across the wide area networks (“WAN's”) such as the World Wide Web. Toward this end, a client-server development platform is provided for handling the important functions of document authoring, content-based indexing and retrieval of documents, management and control of proprietary assets, and a support for developing form-driven interactive services, all in a manner that is uniquely and seamlessly WAN-integrated.

Abstract translation: 本发明解决了出版商寻求通过诸如万维网的广域网（“WAN”）以电子形式创建和发布超媒体内容的关键需求。 为此，提供了一个客户端 - 服务器开发平台，用于处理文档创作，基于内容的索引和文档检索，管理和控制专有资产的重要功能，以及支持开发形式驱动的互动服务 一种独特而无缝的WAN集成方式。

公开(公告)号：US20070033569A1

公开(公告)日：2007-02-08

申请号：US11195327

申请日：2005-08-02

Applicant: James Davidson ,  James Ridgeway ,  Nathan Folkman ,  Richard Landsman

Inventor： James Davidson ,  James Ridgeway ,  Nathan Folkman ,  Richard Landsman

IPC: G06F9/44

CPC classification number: G06F17/30902 ,  H04L43/0811 ,  H04L63/126 ,  H04L67/02 ,  H04L67/1095 ,  H04L67/28 ,  H04L67/2842 ,  H04L67/2861 ,  H04L67/289 ,  H04L2463/121

Abstract: Client-server architectures for allowing web applications to operate even when the client and server are disconnected. Exemplary architectures include a local web engine associated with a local cache which can be separate from a browser cache and browser application. Exemplary data structures include web documents having one or more control commands embedded in the head with manifest code. Exemplary methods include operating web applications when the client is offline, caching web applications, executable code, web documents, security code, and/or remote files, allowing web application access of local files, and operating client/web applications.

公开(公告)号：US20060276452A1

公开(公告)日：2006-12-07

申请号：US10552574

申请日：2004-04-29

Applicant: James Davidson ,  David Adams ,  Michael Bickerdike ,  Alan Fletcher

Inventor： James Davidson ,  David Adams ,  Michael Bickerdike ,  Alan Fletcher

IPC: A61K31/55

CPC classification number: A61K31/397

Abstract: The use of a compound of formula (1): wherein: R1 is aryl; R2 is H, alkyl or aryl; and R3 is hydrogen or alkyl; or a pharmaceutically acceptable salt or prodrug thereof, in the manufacture of a medicament for the treatment of a disorder mediated by CB1 receptors.

Abstract translation: 使用式（1）化合物：其中：R 1是芳基; R 2是H，烷基或芳基; 和R 3是氢或烷基; 或其药学上可接受的盐或前药在制备用于治疗由CB1受体介导的病症的药物中的用途。

公开(公告)号：US07074812B2

公开(公告)日：2006-07-11

申请号：US10633325

申请日：2003-08-02

Applicant: David P. Summers ,  James Davidson

Inventor： David P. Summers ,  James Davidson

IPC: A61K31/44

CPC classification number: A61K31/465

Abstract: In a method of developing muscle mass in a mammal, nicotine or nicotine acetylcholine receptor agonist (nAChR) is administered in combination with exercise to stimulate, recruit and mobilize muscle cells to a specific muscle mass.

Abstract translation: 在哺乳动物中发展肌肉质量的方法中，将尼古丁或尼古丁乙酰胆碱受体激动剂（nAChR）与运动组合施用以刺激，募集和将肌细胞移动到特定肌肉块。

公开(公告)号：US20060042830A1

公开(公告)日：2006-03-02

申请号：US10926882

申请日：2004-08-25

Applicant: Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

Inventor： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

IPC: H05K1/03

CPC classification number: H05K1/032 ,  H05K1/0393 ,  H05K3/4676 ,  H05K2201/0162

Abstract: A flexible cable comprises a cable body of a silicone material and circuits in the flexible cable body. In one embodiment the flexible cable body comprises a multiple number of individual layers of poly(dimethylsiloxane). In one embodiment silicone material encapsulates the individual layers. The flexible cable is made by providing a multiplicity of substrates of a flexible silicone material, producing circuits in the substrates, and stacking the multiplicity of substrates to produce the high density flexible cable.

Abstract translation: 柔性电缆包括硅树脂材料的电缆体和柔性电缆体中的电路。 在一个实施例中，柔性电缆体包括多个单独的聚（二甲基硅氧烷）层。 在一个实施方案中，硅氧烷材料封装各个层。 柔性电缆通过提供多种柔性硅树脂材料的基底，在基底中产生电路，并堆叠多个基底以产生高密度柔性电缆制成。

公开(公告)号：US20060005765A1

公开(公告)日：2006-01-12

申请号：US10885269

申请日：2004-07-06

Applicant: James Davidson

Inventor： James Davidson

IPC: B05B13/02 ,  B05B3/00 ,  B05C5/00

CPC classification number: B05B13/005 ,  B05B13/041

Abstract: A device adapted to dispense or spray a coating such as a foam in a predetermined pattern or manner on a substrate, preferably a roof. The spray coating apparatus comprises a spray assembly having a carriage which is operatively mounted on a track that preferably provides a linear travel path. The carriage is controlled by a drive mechanism which causes reciprocating movement of the carriage. A spray gun is mounted on a holder of the carriage and controlled by an actuator and is used to uniformly apply coatings at a predetermined thickness controlled in part by a spray rate on the intended substrate. In one embodiment, the apparatus includes a cart which is either motorized or manual. The apparatus is lightweight and easily disassembled into sections in order to transport the device from a ground surface to a roof.

公开(公告)号：US20050267579A1

公开(公告)日：2005-12-01

申请号：US11197679

申请日：2005-08-03

Applicant: Mark Reiley ,  Robert Scribner ,  James Davidson

Inventor： Mark Reiley ,  Robert Scribner ,  James Davidson

IPC: A61B17/00 ,  A61B17/16 ,  A61B17/70 ,  A61B17/86 ,  A61F2/00 ,  A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46

CPC classification number: A61F2/4405 ,  A61B17/7064 ,  A61B17/86 ,  A61F2/28 ,  A61F2002/30387 ,  A61F2002/30433 ,  A61F2002/305 ,  A61F2002/30537 ,  A61F2002/30604 ,  A61F2002/30777 ,  A61F2002/30874 ,  A61F2002/449 ,  A61F2002/4631 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2250/0004 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00131 ,  A61F2310/00179 ,  A61F2310/00329 ,  A61F2310/00604 ,  A61F2310/00634 ,  A61F2310/0097 ,  A61F2310/00976 ,  Y10S606/907 ,  Y10S606/91

Abstract: Cephalad and caudal vertebral facet joint prostheses and methods of use are provided. The prostheses provide an artificial facet joint structure including an artificial articular configuration unlike the preexisting articular configuration. The radii and material stress values of the prostheses are configured to sustain contact stress. The cephalad prosthesis provides for posterior-anterior adjustment. Both prostheses permit lateral adjustment and adjustment to accomodate interpedicle distance. Further, the prostheses may be customized to provide a pre-defined lordotic angle and a pre-defined pedicle entry angle.

Abstract translation: 提供头颅和尾椎椎骨小关节假体和使用方法。 所述假体提供与预先存在的关节构造不同的人造关节构造，其包括人造关节构造。 假体的半径和材料应力值被配置为维持接触应力。 头部假体提供前后调整。 两个假体允许横向调整和调整以适应插入距离。 此外，假体可以被定制以提供预定义的脊柱前凸角度和预定义的椎弓根进入角度。

公开(公告)号：US20050187282A1

公开(公告)日：2005-08-25

申请号：US11117459

申请日：2005-04-29

Applicant: Jonathan Roffey ,  James Davidson ,  Howard Mansell ,  Richard Hamlyn ,  David Adams

Inventor： Jonathan Roffey ,  James Davidson ,  Howard Mansell ,  Richard Hamlyn ,  David Adams

IPC: C07D491/048 ,  A61K31/4045 ,  A61K31/407 ,  A61K31/4745 ,  A61P1/04 ,  A61P3/04 ,  A61P7/02 ,  A61P9/10 ,  A61P25/04 ,  A61P25/06 ,  A61P25/08 ,  A61P25/14 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28 ,  A61P25/30 ,  A61P43/00 ,  C07D209/60 ,  C07D209/70 ,  C07D471/04 ,  C07D491/04 ,  C07D491/056 ,  C07D495/04 ,  A61K31/403 ,  C07D209/56

CPC classification number: C07D471/04 ,  A61K31/403 ,  A61K31/404 ,  A61K31/405 ,  A61K31/407 ,  A61K31/437 ,  A61K31/4745 ,  C07D209/60 ,  C07D209/70 ,  C07D209/90 ,  C07D471/06 ,  C07D491/04 ,  C07D491/06 ,  C07D495/04 ,  C07D495/06

Abstract: A chemical compound of formula (I) wherein R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 and R5 are selected from hydrogen and alkyl; R6 and R7 are independently selected from hydrogen, halogen, hydroxyl, alkyl, aryl, amino, alkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, alkylsulfoxyl, nitro, carbonitrile, carbo-alkoxy, carbo-aryloxy and carboxyl; and A is a 5- or 6-membered ring optionally containing one or more heteroatoms wherein the atoms of the ring A, other than the unsaturated carbon atoms of the phenyl ring to which the ring A is fused, are saturated or unsaturated, and pharmaceutically acceptable salts, addition compounds and prodrugs thereof; and the use thereof in therapy, particularly as an agonist or antagonist of a 5HT receptor, particularly a 5HT2C receptor, for instance in the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.

Abstract translation: 式（I）的化合物，其中R 1和R 2各自独立地选自氢和烷基; R 3是烷基; R 4和R 5选自氢和烷基; R 6和R 7独立地选自氢，卤素，羟基，烷基，芳基，氨基，烷基氨基，二烷基氨基，烷氧基，芳氧基，烷硫基，烷基亚砜基，硝基，腈 ，碳 - 烷氧基，碳 - 芳氧基和羧基; 并且A是任选地含有一个或多个杂原子的5-或6-元环，其中除了环A稠合的苯环的不饱和碳原子之外的环A的原子是饱和或不饱和的， 可接受的盐，加成化合物和前药; 以及其在治疗中的用途，特别是作为5HT受体，特别是5HT 2C受体的激动剂或拮抗剂，例如用于治疗中枢神经系统疾病; 损害中枢神经系统; 心血管疾病; 胃肠道疾病; 尿崩症和睡眠呼吸暂停，特别是用于治疗肥胖。

公开(公告)号：US20050030698A1

公开(公告)日：2005-02-10

申请号：US10939771

申请日：2004-09-13

Applicant: Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

Inventor： Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

IPC: A61N1/04 ,  A61N1/05 ,  H01L23/538 ,  H01L25/065 ,  H05K1/00 ,  H05K1/03 ,  H01G4/30

CPC classification number: A61N1/0456 ,  A61B2560/0412 ,  A61N1/0452 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/05 ,  A61N1/0534 ,  H01L23/5387 ,  H01L25/065 ,  H01L2924/0002 ,  H01L2924/09701 ,  H05K1/0313 ,  H05K1/0393 ,  H05K2201/0162 ,  H05K2201/09118 ,  H01L2924/00

Abstract: A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

Abstract translation: 剥离和粘贴电子系统包括硅树脂体和至少一个可操作地连接到硅氧烷体的电子单元。 该电子系统是通过在衬底上提供硅树脂层，在硅树脂层上提供金属层，并提供至少一个与金属层连接的电子单元来制造的。