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21.Cyclic anti-tumor promoter compounds, compositions and methods for production and use 失效
标题翻译: 循环抗肿瘤启动子化合物,用于生产和使用的组合物和方法公开(公告)号:US5349112A
公开(公告)日:1994-09-20
申请号:US157425
申请日:1993-11-26
申请人: Marcus A. Tius
发明人: Marcus A. Tius
IPC分类号: A61K31/045 , A61K31/075 , A61K31/19 , A61K31/215 , A61P35/00 , C07C35/08 , C07C35/18 , C07C35/20 , C07C35/205 , C07C35/21 , C07C43/188 , C07C45/51 , C07C45/67 , C07C49/587 , C07C61/08 , C07C61/10 , C07C61/12 , C07C61/22 , C07C61/26 , C07C61/28 , C07C61/35 , C07C61/39 , C07C62/02 , C07C62/32 , C07C255/16 , C07C255/46 , C07F7/18 , A01N31/00 , C07C63/64 , C07C69/76
CPC分类号: C07C255/46 , A61K31/045 , C07C255/16 , C07C35/18 , C07C35/205 , C07C35/21 , C07C45/511 , C07C45/515 , C07C45/67 , C07C45/673 , C07C49/587 , C07C2101/18
摘要: Novel cyclic anti-tumor promoter compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents.
摘要翻译: 公开了新的环状抗肿瘤促进剂化合物和治疗组合物,以及其生产和用作抗癌剂和癌症预防剂的方法。
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公开(公告)号:US5276217A
公开(公告)日:1994-01-04
申请号:US854414
申请日:1992-03-19
申请人: Marcus A. Tius
发明人: Marcus A. Tius
IPC分类号: A61K31/045 , A61K31/075 , A61K31/19 , A61K31/215 , A61P35/00 , C07C35/08 , C07C35/18 , C07C35/20 , C07C35/205 , C07C35/21 , C07C43/188 , C07C45/51 , C07C45/67 , C07C49/587 , C07C61/08 , C07C61/10 , C07C61/12 , C07C61/22 , C07C61/26 , C07C61/28 , C07C61/35 , C07C61/39 , C07C62/02 , C07C62/32 , C07C255/16 , C07C255/46 , C07F7/18 , A01N31/00 , C07C63/64 , C07C69/76
CPC分类号: C07C255/46 , A61K31/045 , C07C255/16 , C07C35/18 , C07C35/205 , C07C35/21 , C07C45/511 , C07C45/515 , C07C45/67 , C07C45/673 , C07C49/587 , C07C2101/18
摘要: Novel cyclic anti-tumor promoter compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents.
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公开(公告)号:US5118827A
公开(公告)日:1992-06-02
申请号:US555999
申请日:1990-07-16
IPC分类号: C07C33/42 , C07C45/29 , C07C45/51 , C07C47/24 , C07C49/587 , C07C69/65 , C07C255/16 , C07C255/46 , C07F7/18
CPC分类号: C07F7/1856 , C07C255/16 , C07C255/46 , C07C33/423 , C07C45/298 , C07C45/511 , C07C45/512 , C07C47/24 , C07C49/587 , C07C69/65 , C07F7/1852 , C07C2101/18
摘要: Novel monocyclic terpene derivative of the formula: ##STR1## wherein R is hydrogen atom, trimethylsilyl group or 1-ethoxyethyl group, and novel intermediate therefor. The terpene derivative (I) is a useful intermediate for preparing Sarcophytol A having an anti-carcinogenesis promoter activity and an antitumor activity.
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24.Pear flavoring containing a mixture of 2- and 3-cyclotetradecen-1-ones 失效
标题翻译: 含有2-和3-环十四碳烯-1-酮的混合物的梨调味剂公开(公告)号:US4224352A
公开(公告)日:1980-09-23
申请号:US52829
申请日:1979-06-27
申请人: Braja D. Mookherjee , Robert W. Trenkle , Manfred H. Vock , Domenick Luccarelli, Jr. , Frederick L. Schmitt , Gilbert Stork , Timothy MacDonald , Arthur L. Liberman
发明人: Braja D. Mookherjee , Robert W. Trenkle , Manfred H. Vock , Domenick Luccarelli, Jr. , Frederick L. Schmitt , Gilbert Stork , Timothy MacDonald , Arthur L. Liberman
CPC分类号: C11B9/0038 , A23L27/203 , A23L27/29 , C07C45/562 , C07C49/587
摘要: Described is a pear flavoring containing isomer mixtures of 2- and 3-cyclotetradecen-1-ones having the structures: ##STR1##
摘要翻译: 描述了含有具有以下结构的2-和3-环十四碳烯-1-酮的异构体混合物的梨调味剂:
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公开(公告)号:US4183965A
公开(公告)日:1980-01-15
申请号:US973093
申请日:1978-12-26
申请人: Braja D. Mookherjee , Robert W. Trenkle , Manfred H. Vock , Domenick Luccarelli, Jr. , Frederick L. Schmitt , Gilbert Stork , Timothy MacDonald , Arthur L. Liberman
发明人: Braja D. Mookherjee , Robert W. Trenkle , Manfred H. Vock , Domenick Luccarelli, Jr. , Frederick L. Schmitt , Gilbert Stork , Timothy MacDonald , Arthur L. Liberman
IPC分类号: A23F5/46 , A23G3/00 , A23G3/36 , A23L27/20 , A23L27/30 , C07C45/56 , C07C49/587 , C11B9/00 , A23F1/04 , A23L1/22 , A23L1/226 , C12C3/00
CPC分类号: A23G3/36 , A23F5/465 , A23L27/203 , A23L27/30 , C07C45/562 , C07C49/587 , C11B9/0038
摘要: Processes and compositions are described for the use in foodstuff flavor and aroma and perfume and perfumed article aroma augmenting, modifying, altering and enhancing compositions and as foodstuffs, chewing gum, toothpaste, medicinal product, perfume and perfumed article aroma imparting materials of specific isomer and isomer mixtures of 2- and 3-cyclotetradecen-1-ones having the structures: ##STR1## or mixtures of same or mixtures of such 2- and 3-cyclotetradecen-1-ones with cyclotetradecanone having the structure: ##STR2## or cyclododecanone having the structure: ##STR3## Addition of said 2- and 3-cyclotetradecen-1-ones or mixtures is indicated to produce:(a) In food flavorings, a sweet, brown sugar and musky aroma and sweet and musky flavor characteristics (useful for flavor augmentation or enhancement in pear, blackberry, apricot and peach flavors and as a bitterness depressant for such foodstuffs, flavor adjuvants and beverages as black coffee; and(b) In perfumes and perfumed articles, a sweet, musk aroma and exaltone-like, scorched linen, waxy and rooty nuances.
摘要翻译: 描述了用于食品香料和香料和香料和香料制品香气增强,改性,改变和增强组合物以及作为食品,口香糖,牙膏,药用产品,香料和香料赋予特定异构体的芳香赋予材料的方法和组合物, 具有以下结构的2-和3-环十四碳烯-1-酮的异构体混合物:或其混合物或这些2-和3-环十四碳烯-1-酮与环十四烷酮的混合物,其具有以下结构:具有以下结构: 结构:
所述2-和3-环十四碳烯-1-酮或其混合物的添加表明产生:(a)在食品香料中,甜味,红糖和麝香的香气和甜味和麝香风味特征(可用于 梨,黑莓,杏子和桃子香味的香味增强或增强,以及作为黑咖啡的这类食品,风味佐剂和饮料的苦味抑制剂;和(b)在香水和香料中 一种甜美的麝香,麝香香气和高雅的香味,烧焦的亚麻,蜡质和根深蒂固的细微差别。 -
公开(公告)号:US3914315A
公开(公告)日:1975-10-21
申请号:US39907473
申请日:1973-09-20
申请人: TORAY INDUSTRIES
发明人: MIYAKE AKIHISA , KONDO HISAO , NISHIDOI TAKASHI , ONNAGAWA OSAMU
IPC分类号: C07C49/587 , C07C45/00 , C07C45/51 , C07C67/00 , C11B9/00
CPC分类号: C07C45/512 , C07C49/587
摘要: 5-CYCLOHEXADECEN-1-ON IS PREPARED IN A HIGH YIELD BY HEAT TREATING 1,2-DIVINYL-CYCLODODECAN-1-OL IN THE PRESENCE OF N,Ndialkyl carboxylic acid amide, N-alkyl lactam or sulfoxide.
摘要翻译: 在N,N-二烷基羧酸酰胺,N-烷基内酰胺或亚砜存在下,通过热处理1,2-二氨基环己烷-1-醇制备5-环辛烯-1-酮。
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公开(公告)号:US3439056A
公开(公告)日:1969-04-15
申请号:US3439056D
申请日:1967-09-01
发明人: CALDERON NISSIM
IPC分类号: B01J31/02 , B01J31/12 , B01J31/14 , B01J31/22 , B01J31/34 , C07C6/06 , C07C3/10 , C07C3/12 , C07C3/18
CPC分类号: C07C6/06 , B01J31/0202 , B01J31/0217 , B01J31/143 , B01J31/2208 , B01J31/34 , B01J2231/30 , B01J2231/70 , B01J2231/72 , C07C45/27 , C07C45/58 , C07C49/587 , C07C49/395 , C07C49/385
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公开(公告)号:US09758467B2
公开(公告)日:2017-09-12
申请号:US15041112
申请日:2016-02-11
发明人: Benjamin Amorelli , Edward Arruda , Robert Belko , Tingwei Cai , Adam Closson , Nicole Giffin , Gary Mertz , Michael Monteleone
IPC分类号: A61K8/00 , C07C69/75 , A61K8/49 , C11B9/00 , C11D3/50 , A61K8/36 , A61K8/33 , A61Q5/02 , A61Q19/10 , A61Q11/00 , C07D307/87 , C07C47/21 , C07D307/83 , C07C69/96 , C07C43/162 , C07C69/60 , C07C49/385 , C07C49/587 , A61Q13/00 , C11D3/20 , A61K8/37 , A61Q5/00 , A61Q15/00 , A61Q19/00
CPC分类号: C07C69/75 , A61K8/33 , A61K8/36 , A61K8/37 , A61K8/498 , A61Q5/00 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q19/00 , A61Q19/10 , C07C43/162 , C07C47/21 , C07C49/385 , C07C49/587 , C07C69/60 , C07C69/96 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/42 , C07D307/83 , C07D307/87 , C11B9/0015 , C11B9/0019 , C11B9/0034 , C11B9/0038 , C11B9/0076 , C11D3/2072 , C11D3/50
摘要: The present invention relates to novel compounds and their use as fragrance materials.
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29.
公开(公告)号:US09346729B2
公开(公告)日:2016-05-24
申请号:US14821595
申请日:2015-08-07
发明人: Sandip Shinde
IPC分类号: C07C209/60 , C07C67/333 , C07C67/035 , C07C45/62 , C07C45/68 , C07C67/00 , C07C1/207 , C07C45/45 , C07C67/313 , C07C67/343 , C07C67/475 , C07C45/67 , C07C6/04 , C10G3/00 , C07C45/65
CPC分类号: C07C45/68 , C07C1/207 , C07C6/04 , C07C45/455 , C07C45/62 , C07C45/65 , C07C45/676 , C07C67/00 , C07C67/035 , C07C67/313 , C07C67/333 , C07C67/343 , C07C67/475 , C07C209/60 , C07C2531/18 , C07C2531/22 , C07C2601/18 , C10G3/44 , C10G3/52 , C10G2300/1011 , C10G2300/1014 , C10G2300/1018 , C10G2400/20 , C10G2400/22 , C07C69/593 , C07C69/757 , C07C49/587 , C07C11/02 , C07C69/533 , C07C49/385 , C07C211/40 , C07C69/738
摘要: The invention describes methods and systems for making particular organic compounds from unsaturated fatty acids derived from biological materials. Particular embodiments describe synthesizing civetone and olefins from a mixture of palmitoleic and oleic unsaturated fatty acid esters. The inventive methods use reaction steps such as metathesis, cyclization, hydrolysis, and/or decarboxylation.
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公开(公告)号:US20150057207A1
公开(公告)日:2015-02-26
申请号:US14465993
申请日:2014-08-22
发明人: Benjamin Amorelli , Edward Mark Arruda , Robert P. Belko , Tingwei Cai , Adam P. Closson , Nicole L. Giffin , Gary J. Mertz , Michael G. Monteleone
IPC分类号: A61K8/49 , C11D3/50 , A61K8/36 , A61K8/33 , A61Q5/02 , A61Q19/10 , A61Q11/00 , C07D307/87 , C07C47/21 , C07D307/83 , C07C69/96 , C07C43/162 , C07C69/533 , C07C69/75 , C11B9/00
CPC分类号: C07C69/75 , A61K8/33 , A61K8/36 , A61K8/37 , A61K8/498 , A61Q5/00 , A61Q5/02 , A61Q11/00 , A61Q13/00 , A61Q15/00 , A61Q19/00 , A61Q19/10 , C07C43/162 , C07C47/21 , C07C49/385 , C07C49/587 , C07C69/60 , C07C69/96 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/42 , C07D307/83 , C07D307/87 , C11B9/0015 , C11B9/0019 , C11B9/0034 , C11B9/0038 , C11B9/0076 , C11D3/2072 , C11D3/50
摘要: The present invention relates to novel compounds and their use as fragrance materials.
摘要翻译: 本发明涉及新型化合物及其作为香料的用途。
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