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公开(公告)号:US20230305030A1
公开(公告)日:2023-09-28
申请号:US17996419
申请日:2021-04-22
Applicant: GEN-PROBE INCORPORATED
Inventor: Rolf SILBERT
CPC classification number: G01N35/0095 , G01N35/00732 , G01N35/026
Abstract: A system for processing a plurality of sample containers, each containing sample with at least one open assay associated therewith, includes two or more analyzers, each configured to perform at least one functional assay in receptacle apparatuses including a process number of two or more receptacle vessels, a conveyance for transporting containers to the analyzers, a buffer queue associated with each analyzer for holding containers to be processed by the associated analyzer, and a scanner associated with each analyzer. Each scanner scans machine-readable identification information associated with each container transported by the conveyance past the scanner and the open assay(s) for that container are identified based on the scanned information. The sample container is diverted into the associated buffer queue only if at least one open assay for that container matches at least one functional assay of the associated analyzer. The system attempts to accumulate at least the process number of sample containers with the same open assay so that the matching functional assay can be performed on the different samples in each of the process number of receptacle vessels of each receptacle apparatus.
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公开(公告)号:US11761026B2
公开(公告)日:2023-09-19
申请号:US17842535
申请日:2022-06-16
Applicant: Gen-Probe Incorporated
Inventor: David Opalsky , Byron J. Knight
IPC: C12Q1/6806 , C12Q1/686 , G01N35/04 , B01L3/00 , B01L7/00
CPC classification number: C12Q1/6806 , B01L3/50825 , B01L3/565 , B01L7/5255 , C12Q1/686 , G01N35/04 , B01L3/527 , B01L2200/026 , B01L2200/0689 , B01L2300/046 , G01N2035/0418 , G01N2035/0436
Abstract: A nucleic acid diagnostic system includes a unit-dose reagent compartment storing at least one unit-dose pack, one or more unit-dose pack loading stations for holding a unit-dose pack at a location that permits a substance transfer device to dispense a reconstitution reagent into each well of the pack, a unit-dose pack distributor configured to transfer a unit-dose pack from the unit-dose reagent compartment to one of the unit-dose pack loading stations, and an electrostatic generator disposed within the housing of the unit-dose reagent compartment and/or adjacent the one or more unit-dose pack loading stations. The electrostatic generator imparts an electrostatic charge to each of the wells of the unit-dose pack and/or to a lyophilized reagent pellet within each well so that the electrostatic charge positions and holds each lyophilized reagent pellet at a bottom of each respective well of the unit-dose pack.
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公开(公告)号:US20230243001A1
公开(公告)日:2023-08-03
申请号:US18015619
申请日:2021-07-19
Applicant: Gen-Probe Incorporated
Inventor: Barbara L. Eaton , Benjamin Grobarczyk , Laurent Franzil
IPC: C12Q1/689
CPC classification number: C12Q1/689 , C12Q2600/106 , C12Q2600/156
Abstract: Provided are methods, compositions, and systems for detecting nucleic acids of macrolide-resistant Mycoplasma geni-talium using FRET probes for detecting SNPs at position 2058 and 2059.
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公开(公告)号:US20230204616A1
公开(公告)日:2023-06-29
申请号:US18111865
申请日:2023-02-20
Applicant: Gen-Probe Incorporated
Inventor: Rolf SILBERT , David Opalsky , David Aaron Buse , Robert J. Rosati , Olev Tammer , Richard Capella , Matthias Merten
CPC classification number: G01N35/1004 , G01N35/1079 , G01N35/1016 , G01F23/265 , G01N35/025 , G01N35/04 , G01N1/28 , G01N1/31 , G01N35/0099 , G01N35/00732 , G01N35/1002 , G01N2035/1018 , G01N2035/1046 , G01N2035/00524 , C40B60/12
Abstract: A sample processing station includes two or more container holders on a platform that is rotatable about a central axis of rotation. Each holder is configured to rotate about a secondary axis of rotation. The station includes a capping/decapping mechanism to cap or decap a container held in one of the container holders and an elevator with a chuck guide that contact the container holder as the chuck is lowered by the elevator to positon the chuck with respect to the cap of the container held in the holder and to hold jaws of the container holder in a closed position. In embodiment, the chuck guide includes a yoke with opposed arms and spindles located near distal ends of the arms that engage beveled shoulders of the container holder.
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公开(公告)号:US11685957B2
公开(公告)日:2023-06-27
申请号:US17199683
申请日:2021-03-12
Applicant: Gen-Probe Incorporated
Inventor: Scott Higgins , Mike Webb
IPC: C12Q1/6886 , C12Q1/6848 , C12Q1/686 , C12Q1/6851
CPC classification number: C12Q1/6886 , C12Q1/686 , C12Q1/6848 , C12Q1/6851 , C12Q2545/101 , C12Q2545/114 , C12Q2600/112 , C12Q2600/156 , C12Q2600/16 , C12Q1/6848 , C12Q2545/101
Abstract: Methods, kits, and compositions for evaluating the quality of nucleic acids within a biological sample for analysis in a molecular assay are provided.
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公开(公告)号:US20230176084A1
公开(公告)日:2023-06-08
申请号:US17996924
申请日:2021-04-22
Applicant: GEN-PROBE INCORPORATED
Inventor: Rolf SILBERT , David H. COMBS
CPC classification number: G01N35/0099 , B25J9/026 , B25J13/086 , B25J15/10 , B25J15/0033
Abstract: A gripper apparatus is configured to grasp a closed receptacle having a closure affixed to an open top end of a receptacle. Opposed jaw members capable of lateral movement between an open position, a first closed position, and a second closed position are configured to grasp the closed receptacle when the closed receptacle is situated between the jaw members at the first closed position and to release the closed receptacle at the open position. The gripper apparatus further includes a plurality of fingers configured to grasp a sidewall of the closure beneath a top surface of the closure when the closure is situated between the plurality of fingers and beneath a base of each of the jaw members as the jaw members move laterally toward each other from the open position to the second closed position.
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公开(公告)号:USD987850S1
公开(公告)日:2023-05-30
申请号:US29755963
申请日:2020-10-23
Applicant: GEN-PROBE INCORPORATED
Designer: David A. Buse
Abstract: FIG. 1 is a top front perspective view of a receptacle holder showing the claimed design;
FIG. 2 is a bottom rear perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top view thereof; and,
FIG. 8 is a bottom view thereof.
The broken lines in the figures show portions of the receptacle holder that form no part of the claimed design.-
公开(公告)号:US20230087588A1
公开(公告)日:2023-03-23
申请号:US17820256
申请日:2022-08-17
Applicant: GEN-PROBE INCORPORATED
Inventor: Mehrdad R. MAJLESSI , Ankur Shah , Amber Hillius , Pamela Douglass , Daniel Kolk
IPC: C12Q1/6844 , C12Q1/70
Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
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公开(公告)号:US11543349B2
公开(公告)日:2023-01-03
申请号:US17321907
申请日:2021-05-17
Applicant: GEN-PROBE INCORPORATED
Inventor: Norbert D. Hagen , David Opalsky , George T. Walker , Byron J. Knight
Abstract: Method for calibrating or monitoring performance of an optical measurement device that includes using a robotic arm to move a reference device having an optical reference material into a signal-detecting position of the optical measurement device. With the optical measurement device, detecting an emission emitted by the optical reference material of the reference device in the signal-detecting position. Then generating a reference signal representing a characteristic of the emission detected by the optical measurement device and comparing the reference signal to an expected reference signal for the emission to calibrate or monitor the performance of the optical measurement device.
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公开(公告)号:US20220396786A1
公开(公告)日:2022-12-15
申请号:US17775053
申请日:2020-11-13
Applicant: Gen-Probe Incorporated
Inventor: Marcela Alejandra Carvallo Pinto , Ankur H. Shah
IPC: C12N15/10
Abstract: Capture mixtures and activated capture mixtures are provided that are useful for nucleic acid separation and purification are provided. The mixtures comprise lithium lauryl sulfate, lithium hydroxide, a zwitterionic sulfonic acid buffering agent, and optionally, proteinase K, capture probes comprising a first specific binding partner (SBP), and a second specific binding partner immobilized to a solid support. Related combinations, methods, uses, and kits, are also provided.
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