公开(公告)号：US20050250200A1

公开(公告)日：2005-11-10

申请号：US11121096

申请日：2005-05-04

申请人： Akihisa Nakajima ,  Eiichi Ueda ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Nobuhisa Ishida

发明人： Akihisa Nakajima ,  Eiichi Ueda ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Nobuhisa Ishida

IPC分类号： B01F5/06 ,  B01F13/00 ,  B01F15/02 ,  B01L3/00 ,  C12M1/00 ,  C12M1/34 ,  C12N15/09 ,  C12Q1/68 ,  G01N33/53 ,  G01N37/00

CPC分类号： B01L3/50273 ,  B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/024 ,  B01L3/502723 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0439 ,  B01L2400/0487 ,  B01L2400/0605 ,  B01L2400/0633 ,  B01L2400/0677

摘要： A micro-reactor for analyzing a sample, comprises (1) a plate-shaped chip; (2) a plurality of regent storage sections each having a chamber to store respective agents; (3) a regent mixing section to mix plural regents fed from the plurality of regent storage sections so as to produce a mixed reagent; (4) a sample receiving section having an injection port through which a sample is injected from outside; and (5) a reacting section to mix and react the mixed regent fed from the reagent mixing section and the sample fed from the sample receiving section. The plurality of regent storage sections, the regent mixing section, the sample receiving section and the reacting section are incorporated in the chip and are connected through flow paths, and the regent mixing section includes a feed-out preventing mechanism to prevent an initially-mixed regent from being fed out to the reacting section.

摘要翻译： 用于分析样品的微反应器包括（1）板状芯片; （2）多个存储部分，每个存储部分具有用于存储相应代理的室; （3）注射混合部，混合从多个摄取储存部供给的多个药剂，以制备混合试剂; （4）具有从外部注入样品的注入口的样本接收部分; 和（5）反应部分，用于混合并反应从试剂混合部分供给的混合的试剂和从样品接收部分供给的样品。 多个摄取储存部分，摄取混合部分，样品接收部分和反应部分结合在芯片中并且通过流动路径连接，并且注射混合部分包括防止初始混合的防止出料机构 摄政从被送到反应部分。

公开(公告)号：US06322198B1

公开(公告)日：2001-11-27

申请号：US09286637

申请日：1999-04-02

申请人： Kusunoki Higashino ,  Hisashi Takata ,  Yasuhiro Sando ,  Yasuhisa Fujii

发明人： Kusunoki Higashino ,  Hisashi Takata ,  Yasuhiro Sando ,  Yasuhisa Fujii

IPC分类号： B41J204

CPC分类号： B41J2/14314

摘要： An electrostatic inkjet head has first and second electrodes. The first electrode is supported on a substrate and the second electrode is on a diaphragm so that a gap is formed between the first and second electrodes. A drive circuit is connected to the first and second electrodes to apply a voltage or pulse between the electrodes. When a voltage is applied between the electrodes, an electrostatic attraction force is generated between the electrodes. The attraction force displaces the diaphragm toward the substrate. This displacement of the diaphragm is used for the ejection of ink. Also, when the voltage is turned off, opposing central portions of the first and second electrodes define a gap that is greater than that defined by opposing end portions of the first and second electrodes. On the other hand, when the voltage is turned on, the opposing central portions of the first and second electrodes define another gap that is substantially equal to that defined by the opposing end portions of the first and second electrodes.

摘要翻译： 静电喷墨头具有第一和第二电极。 第一电极被支撑在基板上，并且第二电极在隔膜上，使得在第一和第二电极之间形成间隙。 驱动电路连接到第一和第二电极以在电极之间施加电压或脉冲。 当在电极之间施加电压时，在电极之间产生静电吸引力。 吸引力将隔膜移向基板。 隔膜的这种位移用于喷墨。 此外，当电压关闭时，第一和第二电极的相对的中心部分限定了大于由第一和第二电极的相对端部限定的间隙的间隙。 另一方面，当电压接通时，第一和第二电极的相对的中心部分限定了与由第一和第二电极的相对端部限定的间隙基本相等的另一间隙。

公开(公告)号：US08444396B2

公开(公告)日：2013-05-21

申请号：US12699331

申请日：2010-02-03

申请人： Kusunoki Higashino ,  Yasuhisa Fujii ,  Shunichi Hayamizu ,  Yasuhiro Sando

发明人： Kusunoki Higashino ,  Yasuhisa Fujii ,  Shunichi Hayamizu ,  Yasuhiro Sando

IPC分类号： F04B25/00 ,  F04B17/03

CPC分类号： F16K99/0001 ,  B01L3/5027 ,  F04B43/043 ,  F15C5/00 ,  F16K99/0015 ,  F16K99/0048 ,  F16K2099/0074 ,  F16K2099/0094 ,  Y10T137/2224 ,  Y10T137/2273

摘要： Disclosed herein is a micro fluid transferring system that comprises a micropump having a chamber, a first fluid transferring portion connected to the chamber, and a second fluid transferring portion connected to the chamber. This system is characterized in that at least one of the first and second fluid transferring portions comprises a pressure absorbing section for absorbing or alleviating a liquid vibrational pressure therein.

公开(公告)号：US20130063530A1

公开(公告)日：2013-03-14

申请号：US13697994

申请日：2011-04-27

申请人： Kusunoki Higashino ,  Shinya Matsuda

发明人： Kusunoki Higashino ,  Shinya Matsuda

IPC分类号： B41J2/045 ,  H01L41/09

CPC分类号： H01L41/0973 ,  B41J2/14233 ,  B41J2/161 ,  B41J2/1623 ,  B41J2/1628 ,  B41J2/1631 ,  B41J2/1645 ,  B41J2/1646 ,  B81B3/0072 ,  B81B2201/032 ,  B81B2203/0127 ,  H01L41/0475

摘要： An electromechanical transducer (1) has a pressurizing chamber (21) and a side-chamber (23) formed in a plate (11). On a driven film (13) forming the upper wall surface (21a) of the pressurizing chamber (21) and the side-chamber (23), a lower electrode (33), a driving member, and an upper electrode (35) are formed in this order. The driving member is composed of an operation section (31p) located over the pressurizing chamber (21), and an extended section (31a) extending from the operation section (31p) to over the side-chamber (23). The side-chamber (23) has a smaller width than the pressurizing chamber (21) in a second direction perpendicular to a first direction in which the side-chamber (23) is located beside the pressurizing chamber (21). The extended section (31a) of the driving member has a smaller width than the side-chamber (23) in the second direction.

摘要翻译： 机电换能器（1）具有形成在板（11）中的加压室（21）和侧室（23）。 在形成加压室（21）的上壁面（21a）和侧室（23）的从动膜（13）上，下电极（33），驱动部件和上电极（35） 按此顺序形成。 驱动部件由位于加压室（21）的上方的操作部（31p）和从操作部（31p）延伸到侧室（23）的延伸部（31a）构成。 侧室（23）在垂直于侧室（23）位于加压室（21）旁边的第一方向的第二方向上具有比加压室（21）更小的宽度。 驱动构件的延伸部（31a）在第二方向上具有比侧室（23）更小的宽度。

公开(公告)号：US20120156800A1

公开(公告)日：2012-06-21

申请号：US13393020

申请日：2010-09-03

申请人： Youichi Aoki ,  Kusunoki Higashino ,  Naoki Hikage

发明人： Youichi Aoki ,  Kusunoki Higashino ,  Naoki Hikage

IPC分类号： G01N1/28 ,  G01N21/55 ,  G01N21/64 ,  B01L3/00

CPC分类号： B01L3/50273 ,  B01L2200/0684 ,  B01L2200/143 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0877 ,  G01N21/553 ,  G01N21/648 ,  G01N33/54373 ,  G01N2035/00158 ,  G01N2035/106 ,  Y10T436/2575

摘要： A liquid feeding system for a microchip performs: a first liquid feeding step in which a sample liquid in a sample liquid containing section is fed in the direction to a primary containing section via a reaction field; a second liquid feeding step in which, after the first liquid feeding step, the sample liquid is fed from the primary containing section in the direction to the reaction field; and a third liquid feeding step in which, after the second liquid feeding step, the feedings of the sample liquid from and to the reaction field and the primary containing section a rear side gas-liquid boundary face of the sample liquid in the first liquid feeding step and the front side and rear side gas-liquid boundary faces of the sample liquid in the second and third liquid feeding steps do not pass through the reaction field.

摘要翻译： 用于微芯片的液体供给系统执行：第一液体供给步骤，其中样品液体容纳部分中的样品液体经由反应场沿着方向被供给到初级容纳部分; 第二液体供给步骤，在第一供液步骤之后，将样品液体从主容纳部分沿着反应场方向进料; 以及第三液体供给步骤，其中在所述第二供液步骤之后，所述样品液体从所述反应场和所述主容纳部分进料到所述第一液体进料中的样品液体的后侧气液界面 第二和第三液体供给步骤中的样品液体的前侧和后侧气液界面不通过反应场。

公开(公告)号：US20100261290A1

公开(公告)日：2010-10-14

申请号：US12803060

申请日：2010-06-18

申请人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki ,  Kohsuke Tanimoto

发明人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki ,  Kohsuke Tanimoto

IPC分类号： G01N1/00

CPC分类号： G01N35/1095 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2400/0487 ,  B01L2400/0688 ,  G01N27/44756 ,  G01N2035/00158 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/2575

摘要： In the case of passing a reagent in a reaction channel in a microchip, which carries a reactant capable of reacting with the reagent on the wall thereof, and bringing the reactant into contact with the reagent so as to carry out a reaction, the reagent is efficiently passed to the reactant to thereby promote the progress of the reaction. In carrying out the reaction as described above, the reagent (30a) is passed in such a manner that the periphery of the gas/liquid interface at the front end of the reagent moves forward and backward along the wall face of the reaction channel (10). After the completion of the reaction between the reagent (30a) and the reactant, another reagent (30b), which is to be reacted with the reactant capable of reacting with the reagent that is carried on the reaction channel, is passed into the reaction channel (10) while providing a gas in the front edge side thereof. In carrying out the reaction, the reagent (30b) is passed in such manner that the periphery of the gas/liquid interface at the front end of the reagent moves forward and backward along the wall face of the reaction channel (10).

摘要翻译： 在将反应物通过试剂的微芯片中，其携带能够与其壁上的试剂反应的反应物，并使反应物与试剂接触以进行反应，试剂为 有效地传递到反应物中，从而促进反应的进行。 在进行如上所述的反应时，试剂（30a）以这样的方式通过，即试剂前端的气/液界面的周边沿着反应通道（10）的壁面前后移动 ）。 反应物（30a）与反应物反应结束后，与反应物反应的反应物（反应物）与反应通道反应物反应的另一试剂（30b）进入反应通道 （10），同时在其前缘侧提供气体。 在进行反应时，试剂（30b）以这样的方式通过，使得试剂前端处的气/液界面的周边沿着反应通道（10）的壁面向前和向后移动。

公开(公告)号：US07666538B2

公开(公告)日：2010-02-23

申请号：US11005747

申请日：2004-12-07

申请人： Nobuhisa Ishida ,  Yasuhiro Sando ,  Kusunoki Higashino

发明人： Nobuhisa Ishida ,  Yasuhiro Sando ,  Kusunoki Higashino

IPC分类号： H01M2/00

CPC分类号： H01M8/1009 ,  H01M8/04156 ,  H01M8/04194 ,  H01M8/04291 ,  H01M8/1011 ,  Y02E60/523

摘要： A fuel cell device has a small and compact structure as a whole. The fuel cell device employs a fuel cell (e.g., direct methanol fuel cell of an MEA structure) using liquid fuel. Diluted liquid fuel is prepared by diluting the liquid fuel (methanol-contained liquid in the case of DMFC) with dilution liquid, and is supplied to the fuel cell. A first pump unit stacked on the fuel cell supplies the diluted liquid fuel to the fuel cell while diluting the liquid fuel by mixing the liquid fuel and the dilution liquid together. A second pump unit stacked on the fuel cell collects liquid (water usable as dilution liquid in DMFC) produced by an electrochemical reaction in the fuel cell.

摘要翻译： 燃料电池装置整体上具有小而紧凑的结构。 燃料电池装置采用液体燃料的燃料电池（例如MEA结构的直接甲醇燃料电池）。 通过稀释液体燃料（在DMFC的情况下含有甲醇的液体）稀释液体来制备稀释的液体燃料，并将其供应到燃料电池。 堆叠在燃料电池上的第一泵单元将稀释的液体燃料供应到燃料电池，同时通过将液体燃料和稀释液混合在一起来稀释液体燃料。 堆叠在燃料电池上的第二泵单元收集通过燃料电池中的电化学反应产生的液体（可用作DMFC中的稀释液体的水）。

公开(公告)号：US20090233378A1

公开(公告)日：2009-09-17

申请号：US12225598

申请日：2007-02-21

申请人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki ,  Kohsuke Tanimoto

发明人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki ,  Kohsuke Tanimoto

IPC分类号： G01N21/00 ,  G01N1/00

CPC分类号： G01N35/1095 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2400/0487 ,  B01L2400/0688 ,  G01N27/44756 ,  G01N2035/00158 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/2575

摘要： In case of performing a reaction between reacting material and reagent by bringing the reagent in contact with the reacting material through flowing the reagent into a reaction flow channel in which the reaction material which reacts with the reagent is carried on a wall surface of the reaction flow channel of a microchip, the reaction is expedited efficiently by passing the reagent to the reacting material. The reagent 30a is flowed such that a peripheral portion of a gas-liquid interface at a front end of the reagent moves back and forth on the wall surface of the reaction flow channel 10 when the reaction is performed.

摘要翻译： 通过使试剂与反应物质接触而使反应物质与试剂反应的反应流入反应流路，反应物质与反应物质反应的反应物质与试剂反应的反应物质在反应流的壁面上进行反应 微芯片的通道，通过使试剂通过反应材料而有效地加速反应。 试剂30a流动，使得当进行反应时，试剂前端的气 - 液界面的周边部分在反应流路10的壁表面上来回移动。

公开(公告)号：US20080118369A1

公开(公告)日：2008-05-22

申请号：US11940598

申请日：2007-11-15

申请人： Yasuhiro Sando ,  Akihisa Nakajima ,  Kusunoki Higashino ,  Youichi Aoki

发明人： Yasuhiro Sando ,  Akihisa Nakajima ,  Kusunoki Higashino ,  Youichi Aoki

IPC分类号： F04B49/00

CPC分类号： F04B43/043 ,  B01L3/50273 ,  B01L7/00 ,  B01L2200/14 ,  B01L2200/143 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/1822 ,  B01L2400/0487 ,  G01N2035/1034 ,  G01P13/0006 ,  G05D7/0694

摘要： An objective is to provide a microchip inspection system in which an amount of driving liquid filled in a flow path between a micropump and a microchip is kept constant. Also disclosed is a microchip inspection system possessing a micropump by which driving liquid is injected into a microchip from a flow path; a driving liquid sensing device by which a sensing signal is output by sensing presence or absence of the driving liquid at a predetermined position of the flow path; and a pump driving control section by which the driving liquid is moved to a position based on the predetermined position as a reference position by driving the micropump in response to the sensing signal obtained from the driving liquid sensing device.

摘要翻译： 目的是提供一种微芯片检查系统，其中填充在微型泵和微芯片之间的流动路径中的驱动液体的量保持恒定。 还公开了一种具有微型泵的微芯片检查系统，通过该微泵将驱动液体从流路注入微芯片; 驱动液体检测装置，通过在所述流路的预定位置处感测驱动液体的存在或不存在来输出感测信号; 以及泵驱动控制部，通过利用从驱动液体检测装置得到的感测信号，通过驱动微型泵将驱动液体移动到基于规定位置的位置作为基准位置。

公开(公告)号：US20080101992A1

公开(公告)日：2008-05-01

申请号：US11923234

申请日：2007-10-24

申请人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki

发明人： Akihisa Nakajima ,  Kusunoki Higashino ,  Yasuhiro Sando ,  Youichi Aoki

IPC分类号： B01J19/00

CPC分类号： B01L3/502707 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/049 ,  B01L2300/069 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/1822 ,  B01L2400/0439 ,  B01L2400/0677

摘要： An objective is to provide a microchip exhibiting no scattering of stored reagent together with reduced size, which is capable of rapidly mixing the reagent when used. Also disclosed is a microchip possessing a reaction section in which reaction with a reagent or a specimen supplied from a flow path is conducted via heat, wherein the reaction section possesses a storage section to store the reagent in advance, and the reagent previously stored in the storage section is sealed with a material which generates phase transition from a solid phase to a liquid phase between a storage temperature and a reaction temperature.

摘要翻译： 目的是提供一种显示不存在的试剂的散射的微芯片以及减小的尺寸，其能够在使用时快速混合试剂。 还公开了具有反应部的微芯片，其中与从流路供给的试剂或试样的反应通过加热进行反应，其中反应部具有预先存储试剂的储存部，预先存储在试剂中的试剂 存储部分用在储存温度和反应温度之间产生从固相到液相的相变的材料密封。