公开(公告)号：US20130206230A1

公开(公告)日：2013-08-15

申请号：US13808571

申请日：2011-07-22

申请人： Srinivasan Sridharan ,  Robert P. Blonski ,  Chandrashekhar Khadilkar ,  John J. Maloney

发明人： Srinivasan Sridharan ,  Robert P. Blonski ,  Chandrashekhar Khadilkar ,  John J. Maloney

IPC分类号： B23K1/19 ,  B23K31/02 ,  H01L31/18 ,  H05K13/00 ,  H01L31/048

CPC分类号： B23K1/0008 ,  B23K1/0016 ,  B23K1/002 ,  B23K1/005 ,  B23K1/0053 ,  B23K1/0056 ,  B23K1/06 ,  B23K1/19 ,  B23K31/02 ,  B23K35/262 ,  C03C27/08 ,  H01G9/2077 ,  H01L23/10 ,  H01L31/048 ,  H01L31/0488 ,  H01L31/18 ,  H01L51/5246 ,  H01L2924/0002 ,  H01L2924/09701 ,  H01L2924/12044 ,  H05K13/00 ,  Y02E10/50 ,  Y10T156/10 ,  Y10T156/1062 ,  H01L2924/00

摘要： Solder can be used to wet and bind glass substrates together to ensure a hermetic seal that superior (less penetrable) than conventional polymeric (thermoplastic or thermoplastic elastomer) seals in electric and electronic applications.

摘要翻译： 焊接可用于将玻璃基板湿润并粘合在一起，以确保在电气和电子应用中比常规聚合物（热塑性或热塑性弹性体）密封件更好（更不易穿透）的气密密封。

公开(公告)号：US20120219521A1

公开(公告)日：2012-08-30

申请号：US13468956

申请日：2012-05-10

申请人： Eugene T. Michal ,  Evgenia Mandrusov ,  Charles D. Claude ,  Ni Ding ,  Murthy Simhambhatia ,  Syed Faiyez Ahmed Hossainy ,  Srinivasan Sridharan ,  Paul Consigny

发明人： Eugene T. Michal ,  Evgenia Mandrusov ,  Charles D. Claude ,  Ni Ding ,  Murthy Simhambhatia ,  Syed Faiyez Ahmed Hossainy ,  Srinivasan Sridharan ,  Paul Consigny

IPC分类号： A61K31/765 ,  A61M25/00

CPC分类号： A61K9/0019 ,  A61K9/0024 ,  A61K31/7088

摘要： Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle. In other embodiments, the method includes the introduction of structurally reinforcing agents. In other embodiments, agents are introduced into a ventricle to increase compliance of the ventricle. In an alternative embodiment, the prevention of remodeling includes the prevention of thinning of the ventricular infarct zone. In another embodiment, the prevention of remodeling and thinning of the infarct zone involves the cross-linking of collagen and prevention of collagen slipping. In other embodiments, the structurally reinforcing agent may be accompanied by other therapeutic agents. These agents may include but are not limited to pro-fibroblastic and angiogenic agents.

摘要翻译： 用于治疗心肌梗塞的方法，装置，试剂盒和组合物。 在一个实施例中，该方法包括防止脑室梗死区的重塑。 在其它实施方案中，该方法包括引入结构上增强剂。 在其它实施方案中，将药剂引入心室以增加心室的依从性。 在替代实施例中，预防重塑包括防止心室梗塞区变薄。 在另一个实施方案中，预防梗塞区的重塑和变薄包括胶原蛋白的交联和预防胶原蛋白滑脱。 在其它实施方案中，结构上增强剂可以伴随其它治疗剂。 这些药剂可以包括但不限于前成纤维细胞和血管生成剂。

公开(公告)号：US07504349B2

公开(公告)日：2009-03-17

申请号：US11609998

申请日：2006-12-13

申请人： Orville W. Brown ,  Srinivasan Sridharan

发明人： Orville W. Brown ,  Srinivasan Sridharan

IPC分类号： C03C8/18 ,  C03C8/22 ,  H01B1/02

CPC分类号： C03C8/02 ,  C03C3/064 ,  C03C3/066 ,  C03C8/04 ,  C03C8/18 ,  C03C8/22 ,  C04B41/009 ,  C04B41/5127 ,  C04B41/88 ,  C04B2111/00844 ,  H01B1/22 ,  H05K1/092 ,  Y10T428/24909 ,  Y10T428/24926 ,  C04B35/10 ,  C04B41/4539 ,  C04B41/5022 ,  C04B41/5049

摘要： Thick film conductive copper pastes that are lead-free and cadmium-free. The inventive copper pastes possess desirable characteristics, including good solderability, good wire bondability, a low firing temperature, and a wide temperature processing window, and provide excellent adhesion to a variety of substrates, including alumina and glass coated stainless steel substrates, as well as low resistivity, and a microstructure after firing that is dense and substantially free of pores.

摘要翻译： 厚膜导电铜浆，无铅，无镉。 本发明的铜浆具有所需的特性，包括良好的可焊性，良好的线焊接性，低的烧制温度和宽的温度加工窗口，并且对各种基材（包括氧化铝和玻璃涂层的不锈钢基材）以及对 低电阻率和烧结后的微观结构是致密的并且基本上没有孔。

公开(公告)号：US20080103478A1

公开(公告)日：2008-05-01

申请号：US11923068

申请日：2007-10-24

申请人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

发明人： Jessica Chiu ,  Gregory Chan ,  Gabriel Asongwe ,  Robert Esselstein ,  Douglas Gesswein ,  Srinivasan Sridharan ,  Nianjiong Bei ,  William Webler ,  Stephen Schaible ,  Mina Chow ,  Yan Shen ,  Hongzhi Bai ,  Mark Bly ,  Thomas Hatten

IPC分类号： A61M31/00 ,  A61M25/10

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

公开(公告)号：US07339780B2

公开(公告)日：2008-03-04

申请号：US11201278

申请日：2005-08-10

申请人： Srinivasan Sridharan ,  Umesh Kumar

发明人： Srinivasan Sridharan ,  Umesh Kumar

IPC分类号： H01G4/228

CPC分类号： H01G4/232 ,  H01G4/2325 ,  H01G4/30

摘要： A reduction resistant lead-free and cadmium-free glass composition that is particularly suitable for use in conductive ink applications is disclosed. The invention includes a capacitor, which includes a conductive copper termination. The copper termination is made by firing an ink including a glass component, which may include ZnO, provided the amount does not exceed about 65 mole %; B2O3, provided the amount does not exceed about 61 mole %; and, SiO2, provided the amount does not exceed about 63 mole %. The molar ratio of B2O3 to SiO2 is from about 0.05 to about 3.

摘要翻译： 公开了一种特别适用于导电油墨应用的耐还原性无铅和无镉玻璃组合物。 本发明包括电容器，其包括导电铜端接件。 铜终端是通过焙烧包括玻璃组分的油墨制成的，该玻璃组分可以包括ZnO，只要该量不超过约65摩尔％; B 2 O 3 3，条件是该量不超过约61摩尔％; 和SiO 2，条件是该量不超过约63摩尔％。 B 2 O 3 O 3与SiO 2的摩尔比为约0.05至约3。

公开(公告)号：US20070148251A1

公开(公告)日：2007-06-28

申请号：US11317837

申请日：2005-12-22

申请人： Syed Hossainy ,  Florian Ludwig ,  Srinivasan Sridharan

发明人： Syed Hossainy ,  Florian Ludwig ,  Srinivasan Sridharan

IPC分类号： A61K9/14

CPC分类号： A61L31/16 ,  A61L27/34 ,  A61L27/54 ,  A61L31/10 ,  A61L2300/416 ,  A61L2300/624 ,  A61L2300/626 ,  A61L2400/12 ,  A61L2420/04

摘要： Nanoparticles comprising a matrix or shell material and a bioactive agent and medical devices containing the nanoparticles are provided.

摘要翻译： 提供了包含基质或壳材料和生物活性剂的纳米颗粒和含有纳米颗粒的医疗装置。

公开(公告)号：US20060028788A1

公开(公告)日：2006-02-09

申请号：US11201278

申请日：2005-08-10

申请人： Srinivasan Sridharan ,  Umesh Kumar

发明人： Srinivasan Sridharan ,  Umesh Kumar

IPC分类号： H01G9/00

CPC分类号： H01G4/232 ,  H01G4/2325 ,  H01G4/30

摘要： A reduction resistant lead-free and cadmium-free glass composition that is particularly suitable for use in conductive ink applications. The invention includes a capacitor comprising a conductive copper termination, the copper termination is made by firing an ink including a glass component, the glass component may comprise ZnO, provided the amount does not exceed about 65 mole %; B2O3, provided the amount does not exceed about 61 mole %; and, SiO2, provided the amount does not exceed about 63 mole %. The molar ratio of B2O3 to SiO2 is from about 0.05 to about 3.

摘要翻译： 特别适用于导电油墨应用的抗还原性无铅和无镉玻璃组合物。 本发明包括一种包括导电铜端接件的电容器，铜端接件是通过烧制包括玻璃组分的油墨制成的，该玻璃组分可以包含ZnO，只要该量不超过约65摩尔％; B 2 O 3 3，条件是该量不超过约61摩尔％; 和SiO 2，条件是该量不超过约63摩尔％。 B 2 O 3 O 3与SiO 2的摩尔比为约0.05至约3。

公开(公告)号：US20050121824A1

公开(公告)日：2005-06-09

申请号：US11040704

申请日：2005-01-20

申请人： Fernando Gonzalez ,  Srinivasan Sridharan ,  Delma Blankenship

发明人： Fernando Gonzalez ,  Srinivasan Sridharan ,  Delma Blankenship

IPC分类号： B29C61/00 ,  B29C55/22 ,  B29C61/02

CPC分类号： B29C61/006 ,  B29C2049/0089 ,  B29C2049/4655 ,  B29C2791/001 ,  B29K2023/0683 ,  B29K2027/18 ,  B29K2105/258 ,  B29L2031/7542

摘要： A method of making a catheter balloon or other expandable tubular medical device or component thereof formed of a compacted porous polymeric material, in which a tube of porous polymeric material is axially compacted, preferably without increasing the outer diameter of the tube, by positioning heat shrink material on the porous polymeric tube and heating the heat shrink material to decrease the length and diameter of the heat shrink material.

公开(公告)号：US08383158B2

公开(公告)日：2013-02-26

申请号：US10414602

申请日：2003-04-15

申请人： Eugene T. Michal ,  Evgenia Mandrusov ,  Charles D. Claude ,  Ni Ding ,  Murthy Simhambhatla ,  Syed Faiyez Ahmed Hossainy ,  Srinivasan Sridharan ,  Paul Consigny

发明人： Eugene T. Michal ,  Evgenia Mandrusov ,  Charles D. Claude ,  Ni Ding ,  Murthy Simhambhatla ,  Syed Faiyez Ahmed Hossainy ,  Srinivasan Sridharan ,  Paul Consigny

IPC分类号： A61K9/14

CPC分类号： A61N1/3625 ,  A61K9/0024 ,  A61K31/00 ,  A61K31/728 ,  A61K31/732 ,  A61K31/734 ,  A61K31/78 ,  A61K31/79 ,  A61K36/886 ,  A61K38/40 ,  A61K41/0042 ,  A61K45/06 ,  A61K47/02 ,  A61K47/34 ,  A61K47/60 ,  A61K47/62 ,  A61K49/0404 ,  A61L24/043 ,  A61L27/20 ,  A61L27/50 ,  A61L27/54 ,  A61L2430/20 ,  A61N1/36521 ,  A61K2300/00

摘要： Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle. In other embodiments, the method includes the introduction of structurally reinforcing agents. In other embodiments, agents are introduced into a ventricle to increase compliance of the ventricle. In an alternative embodiment, the prevention of remodeling includes the prevention of thinning of the ventricular infarct zone. In another embodiment, the prevention of remodeling and thinning of the infarct zone involves the cross-linking of collagen and prevention of collagen slipping. In other embodiments, the structurally reinforcing agent may be accompanied by other therapeutic agents. These agents may include, but are not, limited to pro-fibroblastic and angiogenic agents.

摘要翻译： 用于治疗心肌梗塞的方法，装置，试剂盒和组合物。 在一个实施例中，该方法包括防止脑室梗死区的重塑。 在其它实施方案中，该方法包括引入结构上增强剂。 在其它实施方案中，将药剂引入心室以增加心室的依从性。 在替代实施例中，预防重塑包括防止心室梗塞区变薄。 在另一个实施方案中，预防梗塞区的重塑和变薄包括胶原蛋白的交联和预防胶原蛋白滑脱。 在其它实施方案中，结构上增强剂可以伴随其它治疗剂。 这些试剂可以包括但不限于前成纤维细胞和血管生成剂。

公开(公告)号：US08182463B2

公开(公告)日：2012-05-22

申请号：US11609143

申请日：2006-12-11

申请人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

发明人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

IPC分类号： A61M31/00

CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.

摘要翻译： 输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉 截面面积至少约5 mm2; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或 合成胶乳 其中所述气囊适于膨胀至约4至约15mm的直径范围。