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    BIOEFFECTIVE KRILL OIL COMPOSITIONS
    43.
    发明申请
    BIOEFFECTIVE KRILL OIL COMPOSITIONS 有权
    生物油橄榄油组合物

    公开(公告)号：US20150164963A1

    公开(公告)日：2015-06-18

    申请号：US14620784

    申请日：2015-02-12

    申请人： AKER BIOMARINE ANTARCTIC AS

    发明人： Inge Bruheim ,  Snorre Tilseth ,  Daniele Mancinelli

    IPC分类号： A61K35/612 ,  A61K31/235 ,  A61K9/48 ,  A61K31/122 ,  A61K31/20

    CPC分类号： A61K35/612 ,  A23L33/115 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K31/122 ,  A61K31/20 ,  A61K31/202 ,  A61K31/215 ,  A61K31/23 ,  A61K31/235 ,  A61K31/575 ,  A61K31/683 ,  A61K31/685 ,  A61K45/06 ,  C11B3/006 ,  A61K2300/00

    摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obatined are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

    摘要翻译： 本发明公开了新的磷虾油组合物，其特征在于含有大量的磷脂，虾青素酯和/或ω-3含量。 磷虾油在两阶段过程中使用超临界流体萃取从磷虾粉中获得。 阶段1通过用纯超临界CO 2或CO 2加上约5％的共溶剂萃取来除去中性脂质。 阶段2通过使用超临界CO2与约20％乙醇组合提取实际的磷虾油。 将磷虾油材料与市售的磷虾油进行比较，发现在抗炎，抗氧化作用，改善胰岛素抵抗和改善血脂特征等多个领域更具生物效力。

    BIOEFFECTIVE KRILL OIL COMPOSITIONS
    47.
    发明申请
    BIOEFFECTIVE KRILL OIL COMPOSITIONS 有权
    生物油橄榄油组合物

    公开(公告)号：US20150004223A1

    公开(公告)日：2015-01-01

    申请号：US14490176

    申请日：2014-09-18

    申请人： AKER BIOMARINE AS

    发明人： Inge Bruheim ,  Snorre Tilseth ,  Daniele Mancinelli

    IPC分类号： A61K35/56

    CPC分类号： A61K35/612 ,  A23L33/115 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K31/122 ,  A61K31/20 ,  A61K31/202 ,  A61K31/215 ,  A61K31/23 ,  A61K31/235 ,  A61K31/575 ,  A61K31/683 ,  A61K31/685 ,  A61K45/06 ,  C11B3/006 ,  A61K2300/00

    摘要： This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.

    摘要翻译： 本发明公开了新的磷虾油组合物，其特征在于含有大量的磷脂，虾青素酯和/或ω-3含量。 磷虾油在两阶段过程中使用超临界流体萃取从磷虾粉中获得。 阶段1通过用纯超临界CO 2或CO 2加上约5％的共溶剂萃取来除去中性脂质。 阶段2通过使用超临界CO2与约20％乙醇组合提取实际的磷虾油。 将所获得的磷虾油材料与市售的磷虾油进行比较，发现在抗炎，抗氧化作用，改善胰岛素抵抗和改善血脂特征等多个领域中具有更高的生物有效性。

    Method for separating neutral and polar lipids and an oil rich in polar lipids
    49.
    发明授权
    Method for separating neutral and polar lipids and an oil rich in polar lipids 有权
    分离中性和极性脂质和富含极性脂质的油的方法

    公开(公告)号：US08865923B2

    公开(公告)日：2014-10-21

    申请号：US13255869

    申请日：2010-03-10

    申请人： Magnus Härröd

    发明人： Magnus Härröd

    IPC分类号： C11B3/00 ,  C07H15/08 ,  C11B7/00 ,  C07H13/06 ,  C07H1/08

    CPC分类号： C11B7/0083 ,  C07H13/06 ,  C11B3/006 ,  C11B7/0025

    摘要： A method for separating neutral and polar lipids from an oil of biological material, wherein the oil is fractionated using a mixture of a polar solvent comprising at least one carbon atom, water and an additional substance selected from the group consisting of: mono-, di- and oligosaccharides comprising from 3 to 10 monosaccharide units, said additional substance is present in an amount of at least 0.1 wt % calculated on the total weight of solvent, water and additional substance, to form at least two liquid fractions having different densities, wherein one fraction is rich in polar lipids and another fraction is rich in neutral lipids. An oil rich in polar lipids obtained from the method is disclosed, said oil I contains at least 40, preferably at least 50 lipid % polar lipids as calculated on the total amount of lipids in said oil and that the total amount of polar solvent and water in said oil is between 20 and 30 wt %. An oat oil containing high amounts of estolides of DGDG can further be obtained.

    摘要翻译： 一种从生物材料的油中分离中性和极性脂质的方法，其中使用包含至少一个碳原子的极性溶剂，水和选自以下的另外的物质的混合物将油分馏：单 - ，二 - 和包含3至10个单糖单元的寡糖，所述另外的物质以基于溶剂，水和附加物质的总重量计算的至少0.1重量％的量存在，以形成至少两个具有不同密度的液体馏分，其中 一部分富含极性脂质，另一部分富含中性脂质。 公开了从该方法获得的富含极性脂质的油，所述油I含有至少40种，优选至少50种脂质％极性脂质，根据所述油中脂质的总量计算，并且极性溶剂和水的总量 在所述油中的含量为20-30重量％。 可以进一步获得含有大量的DGDG的耳塞油的燕麦油。

    Method for lipid extraction from biomass
    50.
    发明授权
    Method for lipid extraction from biomass 有权
    从生物质提取脂质的方法

    公开(公告)号：US08845765B2

    公开(公告)日：2014-09-30

    申请号：US13291306

    申请日：2011-11-08

    申请人： Annika Malm ,  Reijo Tanner ,  Mervi Hujanen

    发明人： Annika Malm ,  Reijo Tanner ,  Mervi Hujanen

    IPC分类号： C10L1/00 ,  C11B1/10 ,  C10L1/02 ,  C10L1/18

    CPC分类号： C11B1/10 ,  C10L1/026 ,  C10L1/18 ,  C10L1/1802 ,  C11B3/006 ,  Y02E50/13

    摘要： A method for recovering lipids from microbial biomass, the method including providing wet microbial biomass which contains lipids to extraction without disrupting the biomass cell walls, and subsequently, extracting the wet microbial biomass with a liquid extractant at elevated temperature of at least 170° C. and elevated pressure. The combination of the temperature and pressure is such that the lipids in the cells are contacted with the extractant. Subsequently the extracted lipids are recovered from or with the extractant.

    摘要翻译： 一种从微生物生物质中回收脂质的方法，该方法包括提供湿微生物生物质，其含有脂质以提取而不破坏生物质细胞壁，随后用液体萃取剂在至少170℃的升高的温度下萃取湿的微生物生物量。 并提高压力。 温度和压力的组合使得细胞中的脂质与萃取剂接触。 随后从提取剂中回收提取的脂质。