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    Porous composite materials
    54.
    发明授权
    Porous composite materials 有权
    多孔复合材料

    公开(公告)号：US06281257B1

    公开(公告)日：2001-08-28

    申请号：US09292896

    申请日：1999-04-16

    申请人： Peter X. Ma ,  Ruiyun Zhang

    发明人： Peter X. Ma ,  Ruiyun Zhang

    IPC分类号： C08J926

    CPC分类号： C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2367/00 ,  C12N5/0068 ,  C12N2533/12 ,  C12N2533/18 ,  C12N2533/30 ,  C12N2533/40 ,  G01N15/14

    摘要： Methods and compositions are described that provide three dimensional porous matrices as structural templates for cells. The porous matrices of the present invention have desirable mechanical properties suitable to a variety of applications, including platforms for in vitro cell cultivation, implants for tissue and organ engineering, and materials suitable for chromatography and filtration.

    摘要翻译： 描述了提供三维多孔基质作为细胞结构模板的方法和组合物。 本发明的多孔基质具有适合于各种应用的理想的机械性能，包括用于体外细胞培养的平台，用于组织和器官工程的植入物，以及适用于色谱和过滤的材料。

    Expansible macromolecular material and porous macromolecular membrane
    56.
    发明授权
    Expansible macromolecular material and porous macromolecular membrane 失效
    可膨胀大分子材料和多孔大分子膜

    公开(公告)号：US4717800A

    公开(公告)日：1988-01-05

    申请号：US031675

    申请日：1987-03-30

    申请人： Makoto Suzuki

    发明人： Makoto Suzuki

    IPC分类号： C08L29/04 ,  A61F2/08 ,  A61F2/68 ,  B25J9/00 ,  B25J9/10 ,  C08F8/00 ,  C08J9/28 ,  C08L29/02 ,  B01D39/14

    CPC分类号： C08J9/28 ,  A61F2/08 ,  A61F2/68 ,  B25J9/0012 ,  B25J9/1095 ,  A61F2002/0894 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2201/0502

    摘要： An expansible macromolecular material is produced by a method which comprises mixing an aqueous polyvinyl alcohol solution, an acidic aqueous macromolecular electrolyte solution, and a basic aqueous macromolecular electrolyte solution thereby preparing a composite polymer and subjecting this composite polymer to at least one cycle of alternate freezing and defrosting treatments. A macromolecular membrane constituted of said expansible macromolecular material and containing numerous through holes is obtained by mixing, freezing, and defrosting the aforementioned three mixed aqueous solutions under specific conditions.

    摘要翻译： 通过包括将聚乙烯醇水溶液，酸性高分子电解质水溶液和碱性高分子电解质水溶液混合从而制备复合聚合物并使该复合聚合物经受至少一个交替冷冻循环的方法制备可膨胀的高分子材料 和除霜治疗。 通过在特定条件下混合，冷冻和除霜上述三种混合水溶液，获得由所述可膨胀大分子材料构成并含有许多通孔的高分子膜。

    Low density microcellular foams
    57.
    发明授权
    Low density microcellular foams 失效
    低密度微孔泡沫

    公开(公告)号：US4673695A

    公开(公告)日：1987-06-16

    申请号：US785436

    申请日：1985-10-08

    申请人： James H. Aubert ,  Roger L. Clough ,  John G. Curro ,  Carlos A. Quintana ,  Edward M. Russick ,  Montgomery T. Shaw

    发明人： James H. Aubert ,  Roger L. Clough ,  John G. Curro ,  Carlos A. Quintana ,  Edward M. Russick ,  Montgomery T. Shaw

    IPC分类号： B01D39/16 ,  B01D67/00 ,  B01D71/28 ,  C08J9/26 ,  C08J9/28

    CPC分类号： C08J9/28 ,  B01D39/1676 ,  B01D67/003 ,  B01D71/28 ,  C08J9/26 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2201/052 ,  C08J2325/06

    摘要： Low density, microporous polymer foams are provided by a process which comprises forming a solution of polymer and a suitable solvent followed by rapid cooling of the solution to form a phase-separated system and freeze the phase-separated system. The phase-separated system comprises a polymer phase and a solvent phase, each of which is substantially continuous within the other. The morphology of the polymer phase prior to and subsequent to freezing determine the morphology of the resultant foam.Both isotropic and anisotropic foams can be produced. If isotropic foams are produced, the polymer and solvent are tailored such that the solution spontaneously phase-separates prior to the point at which any component freezes. The morphology of the resultant polymer phase determines the morphology of the resultant foam and the morphology of the polymer phase is retained by cooling the system at a rate sufficient to freeze one or both components of the system before a change in morphology can occur. Anisotropic foams are produced by forming a solution of polymer and solvent that will not phase separate prior to freezing of one or both components of the solution. In such a process, the solvent typically freezes before phase separation occurs. The morphology of the resultant frozen two-phase system determines the morphology of the resultant foam.The process involves subjecting the solution to essentially one-dimensional cooling. Means for subjecting such a solvent to one-dimensional cooling are also provided.Foams having a density of less than 0.1 g/cc and a uniform cell size of less than 10 .mu.m and a volume such that the foams have a length greater than 1 cm are provided.

    摘要翻译： 通过包括形成聚合物溶液和合适溶剂的方法提供低密度，微孔聚合物泡沫，然后快速冷却溶液以形成相分离系统并冷冻相分离系统。 相分离系统包括聚合物相和溶剂相，其各自在另一个内基本连续。 在冷冻之前和之后的聚合物相的形态决定所得泡沫的形态。 可以生产各向同性和各向异性泡沫。 如果产生各向同性泡沫，则定制聚合物和溶剂使得溶液在任何组分冻结的点之前自发相分离。 所得聚合物相的形态决定了所得泡沫体的形态，并且通过以足以在形态变化发生之前冻结体系的一个或两个组分的速率冷却系统来保留聚合物相的形态。 通过形成聚合物和溶剂的溶液来产生各向异性泡沫，该溶液在溶液的一个或两个组分冷冻之前不会相分离。 在这种过程中，溶剂通常在相分离发生之前冻结。 所得冷冻两相体系的形态决定所得泡沫的形态。 该方法包括使溶液基本上进行一维冷却。 还提供了使这种溶剂进行一维冷却的方法。 具有小于0.1g / cc的密度和小于10μm的均匀泡孔尺寸的泡沫和具有长度大于1cm的泡沫的体积。