-
公开(公告)号：US10143774B2
公开(公告)日：2018-12-04
申请号：US15657868
申请日：2017-07-24
申请人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
发明人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
IPC分类号： A61L27/20 , A61L27/12 , A61L27/56 , A61L27/46 , C08B37/00 , C08B37/02 , C08J9/00 , C08J9/26 , C08J9/28
摘要： The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralization of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.
-
2.发明申请公开(公告)号：US20170319741A1
公开(公告)日：2017-11-09
申请号：US15657868
申请日：2017-07-24
申请人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
发明人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
IPC分类号： A61L27/12 , A61L27/46 , A61L27/56 , C08J9/28 , C08B37/02 , A61L27/20 , C08J9/26 , C08J9/00 , C08B37/00
CPC分类号： A61L27/12 , A61L27/20 , A61L27/46 , A61L27/56 , A61L2300/112 , A61L2400/08 , A61L2400/12 , A61L2430/02 , C08B37/0018 , C08B37/0021 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/026 , C08J2201/0444 , C08J2201/0484 , C08J2205/022 , C08J2207/10 , C08J2305/00 , C08J2405/02
摘要： The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.
-
公开(公告)号：US09757494B2
公开(公告)日：2017-09-12
申请号：US14728412
申请日：2015-06-02
申请人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
发明人： Joelle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
IPC分类号： A61L27/20 , A61L27/12 , A61L27/56 , A61L27/46 , C08B37/00 , C08B37/02 , C08J9/00 , C08J9/26 , C08J9/28
CPC分类号： A61L27/12 , A61L27/20 , A61L27/46 , A61L27/56 , A61L2300/112 , A61L2400/08 , A61L2400/12 , A61L2430/02 , C08B37/0018 , C08B37/0021 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/026 , C08J2201/0444 , C08J2201/0484 , C08J2205/022 , C08J2207/10 , C08J2305/00 , C08J2405/02
摘要： The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stent cells or growth factors.
-
4.发明申请POROUS POLYSACCHARIDE SCAFFOLD COMPRISING NANO-HYDROXYAPATITE AND USE FOR BONE FORMATION 审中-公开包含纳米羟基磷灰石的多糖多糖和用于骨形成的多糖多糖公开(公告)号：US20130224277A1
公开(公告)日：2013-08-29
申请号：US13819546
申请日：2011-08-30
申请人： Joëlle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
发明人： Joëlle Amedee , Didier Letourneur , Catherine Le Visage , Sidi Mohammed Derkaoui , Jean-Christophe Fricain , Sylvain Catros
CPC分类号： A61L27/12 , A61L27/20 , A61L27/46 , A61L27/56 , A61L2300/112 , A61L2400/08 , A61L2400/12 , A61L2430/02 , C08B37/0018 , C08B37/0021 , C08J9/0061 , C08J9/26 , C08J9/28 , C08J2201/026 , C08J2201/0444 , C08J2201/0484 , C08J2205/022 , C08J2207/10 , C08J2305/00 , C08J2405/02
摘要： The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.
摘要翻译： 本发明涉及在不存在干细胞或生长因子的情况下，能够在骨骼部位以及非骨骼部位诱导组织的矿化的三维多孔多糖基质。
-
公开(公告)号：US09381250B2
公开(公告)日：2016-07-05
申请号：US13819437
申请日：2011-08-30
CPC分类号： A61K9/1652 , A61K9/0019 , A61K9/0024 , A61K9/1075 , A61K9/1682 , A61K47/26 , A61L27/20 , A61L2430/02 , A61L2430/06 , A61L2430/20 , C08B37/0018 , C08B37/0021 , Y10T428/2982 , C08L5/00
摘要： The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads are highly useful for tissue engineering, in situ tissue regeneration, as well as for drug and/or cells delivery. In addition, said beads may support biotechnological applications such as cell carriers.
摘要翻译： 本发明涉及适于在人或动物体内使用的生物相容性材料的珠粒。 所述珠对组织工程，原位组织再生以及药物和/或细胞递送非常有用。 此外，所述珠粒可以支持生物技术应用，例如细胞载体。
-
公开(公告)号：US20130171126A1
公开(公告)日：2013-07-04
申请号：US13819437
申请日：2011-08-30
IPC分类号： A61K47/26
CPC分类号： A61K9/1652 , A61K9/0019 , A61K9/0024 , A61K9/1075 , A61K9/1682 , A61K47/26 , A61L27/20 , A61L2430/02 , A61L2430/06 , A61L2430/20 , C08B37/0018 , C08B37/0021 , Y10T428/2982 , C08L5/00
摘要： The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads are highly useful for tissue engineering, in situ tissue regeneration, as well as for drug and/or cells delivery. In addition, said beads may support biotechnological applications such as cell carriers.
摘要翻译： 本发明涉及适于在人或动物体内使用的生物相容性材料的珠粒。 所述珠对组织工程，原位组织再生以及药物和/或细胞递送非常有用。 此外，所述珠粒可以支持生物技术应用，例如细胞载体。
-
公开(公告)号：US09028857B2
公开(公告)日：2015-05-12
申请号：US12681676
申请日：2008-10-10
IPC分类号： A61F13/00 , C07H1/00 , C08B37/02 , A61L27/20 , A61L27/38 , A61L27/50 , A61L27/52 , A61L27/56 , C12N5/00 , C08B37/00 , C08B37/08 , C08H1/06 , C08J9/28
CPC分类号： A61L27/56 , A61L27/20 , A61L27/3804 , A61L27/3826 , A61L27/3834 , A61L27/3847 , A61L27/3852 , A61L27/507 , A61L27/52 , A61L27/54 , A61L2300/21 , A61L2430/02 , A61L2430/06 , C08B37/0018 , C08B37/0021 , C08B37/003 , C08B37/0039 , C08B37/0054 , C08B37/0063 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/06 , C08J3/24 , C08J9/28 , C08J2201/026 , C08J2201/0484 , C08J2205/04 , C08J2207/10 , C08J2305/00 , C08J2305/02 , C08J2305/08 , C08J2305/12 , C12N5/0068 , C12N11/10 , C12N2533/70 , Y10T436/147777
摘要： The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprise the steps consisting of a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide and one cross-linking agent b) freezing the aqueous solution of step a) c) sublimating the frozen solution of step b). characterized in that step b) is performed before the cross-linking of the polysaccharide occurs in the solution of step a).
摘要翻译： 本发明涉及一种用于组织工程的多孔支架的制备方法。 本发明的另一个目的是提供可通过上述方法获得的多孔支架及其在组织工程，细胞培养和细胞递送中的应用。 本发明的方法包括以下步骤：a）制备含有至少一种多糖和一种交联剂的碱性水溶液b）冷冻步骤a）的水溶液c）升华步骤b的冷冻溶液 ）。 其特征在于步骤b）在多糖的交联发生在步骤a）的溶液中之前进行。
-
8.发明申请Method for Preparing Porous Scaffold for Tissue Engineering, Cell Culture and Cell Delivery 有权制备多孔支架用于组织工程，细胞培养和细胞递送的方法公开(公告)号：US20100221303A1
公开(公告)日：2010-09-02
申请号：US12681682
申请日：2008-10-10
IPC分类号： A61K9/00 , B28B1/14 , C12N5/071 , C12N5/077 , C12N5/0775 , C12N5/0735 , C12N5/10 , C12N1/00 , A61K35/12 , A61K35/66 , C12Q1/02 , C12N1/16 , C12N1/19 , C12N5/04 , A61P43/00
CPC分类号： A61L27/20 , A61L27/3804 , A61L27/3834 , A61L27/3847 , A61L27/3852 , A61L27/507 , A61L27/52 , A61L27/54 , A61L27/56 , C08B37/0018 , C08B37/0021 , C08B37/003 , C08B37/0039 , C08B37/0054 , C08B37/0063 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08J9/08 , C08J9/28 , C08J9/283 , C08J2201/026 , C08J2201/0484 , C08J2201/0504 , C08J2205/022 , C08J2207/10 , C08J2305/00 , C08J2305/02 , C08J2305/04 , C08J2305/08 , C08J2305/10 , C08J2305/12 , C12N5/0068 , C12N2533/70 , C12N2533/72 , C12N2533/74
摘要： The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).
摘要翻译： 本发明涉及一种用于组织工程的多孔支架的制备方法。 本发明的另一个目的是提供可通过上述方法获得的多孔支架及其在组织工程，细胞培养和细胞递送中的应用。 本发明的方法包括以下步骤：a）制备包含一定量的多糖，一定量的交联剂和一定量的致孔剂的碱性水溶液b）将溶液转化成水凝胶 通过将所述溶液置于约4℃至约80℃的温度下足够的时间以允许所述量的多糖的交联和c）将所述水凝胶浸入水溶液中d）洗涤多孔支架 在步骤c）获得。
-
9.发明授权Method for preparing porous scaffold for tissue engineering, cell culture and cell delivery 有权用于组织工程，细胞培养和细胞递送的多孔支架的制备方法公开(公告)号：US09522218B2
公开(公告)日：2016-12-20
申请号：US12681682
申请日：2008-10-10
IPC分类号： A61L27/20 , C08J3/075 , C08B37/00 , C08B37/02 , C08B37/04 , C08B37/10 , C08B37/12 , C08J9/08 , A61L27/52 , A61L27/56 , A61L27/38 , A61L27/50 , C12N5/00 , C08B37/08 , C08J9/28
CPC分类号： A61L27/20 , A61L27/3804 , A61L27/3834 , A61L27/3847 , A61L27/3852 , A61L27/507 , A61L27/52 , A61L27/54 , A61L27/56 , C08B37/0018 , C08B37/0021 , C08B37/003 , C08B37/0039 , C08B37/0054 , C08B37/0063 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08J9/08 , C08J9/28 , C08J9/283 , C08J2201/026 , C08J2201/0484 , C08J2201/0504 , C08J2205/022 , C08J2207/10 , C08J2305/00 , C08J2305/02 , C08J2305/04 , C08J2305/08 , C08J2305/10 , C08J2305/12 , C12N5/0068 , C12N2533/70 , C12N2533/72 , C12N2533/74
摘要： The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).
摘要翻译： 本发明涉及一种用于组织工程的多孔支架的制备方法。 本发明的另一个目的是提供可通过上述方法获得的多孔支架及其在组织工程，细胞培养和细胞递送中的应用。 本发明的方法包括以下步骤：a）制备包含一定量的多糖，一定量的交联剂和一定量的致孔剂的碱性水溶液b）将溶液转化成水凝胶 通过将所述溶液置于约4℃至约80℃的温度下足够的时间以允许所述量的多糖的交联和c）将所述水凝胶浸入水溶液中d）洗涤多孔支架 在步骤c）获得。
-
公开(公告)号：US20100221301A1
公开(公告)日：2010-09-02
申请号：US12681676
申请日：2008-10-10
CPC分类号： A61L27/56 , A61L27/20 , A61L27/3804 , A61L27/3826 , A61L27/3834 , A61L27/3847 , A61L27/3852 , A61L27/507 , A61L27/52 , A61L27/54 , A61L2300/21 , A61L2430/02 , A61L2430/06 , C08B37/0018 , C08B37/0021 , C08B37/003 , C08B37/0039 , C08B37/0054 , C08B37/0063 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/06 , C08J3/24 , C08J9/28 , C08J2201/026 , C08J2201/0484 , C08J2205/04 , C08J2207/10 , C08J2305/00 , C08J2305/02 , C08J2305/08 , C08J2305/12 , C12N5/0068 , C12N11/10 , C12N2533/70 , Y10T436/147777
摘要： The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprise the steps consisting of a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide and one cross-linking agent b) freezing the aqueous solution of step a) c) sublimating the frozen solution of step b). characterized in that step b) is performed before the cross-linking of the polysaccharide occurs in the solution of step a).
摘要翻译： 本发明涉及一种用于组织工程的多孔支架的制备方法。 本发明的另一个目的是提供可通过上述方法获得的多孔支架及其在组织工程，细胞培养和细胞递送中的应用。 本发明的方法包括以下步骤：a）制备含有至少一种多糖和一种交联剂的碱性水溶液b）冷冻步骤a）的水溶液c）升华步骤b的冷冻溶液 ）。 其特征在于在步骤a）的溶液中发生多糖的交联之前进行步骤b）。
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.029 秒)
