SOFT FILLED PROSTHESIS SHELL WITH DISCRETE FIXATION SURFACES

    公开(公告)号:US20180200045A1

    公开(公告)日:2018-07-19

    申请号:US15923932

    申请日:2018-03-16

    申请人: Allergan, Inc.

    摘要: A soft prosthetic implant shell, such as a silicone breast implant shell, that has discrete fixation surfaces thereon for tissue adhesion. The fixation surfaces may be provided on the posterior face of the shell, as well as either on the periphery or at discrete areas on the anterior face. Band-shaped fixation surfaces may be provided on the anterior face of the shell to generally match the angle of pectoralis major or pectoralis minor muscle groups. The fixation surfaces may be roughened areas of the shell, or may be separate elements adhered to the shell.

    COMPOSITION FOR ENTERIC HARD CAPSULE AND METHOD FOR PRODUCING ENTERIC HARD CAPSULE

    公开(公告)号:US20180015045A1

    公开(公告)日:2018-01-18

    申请号:US15641952

    申请日:2017-07-05

    发明人: Naosuke MARUYAMA

    IPC分类号: A61K9/48 B29C41/14 B29K1/00

    摘要: A composition for an enteric hard capsule by taking advantage of conventionally unknown thermal gelation characteristics of a neutralized aqueous solution of an enteric polymer, so as to obtain an enteric capsule having sufficient water and acid resistances. More specifically, the composition has hypromellose acetate succinate having a molar substitution with an acetyl group per anhydroglucose unit of 0.6 to 0.8 and a ratio of the molar substitution with an acetyl group to a molar substitution with a succinyl group per anhydroglucose unit of 2.0 to 4.0, a neutralizer, and water method produces an enteric hard capsule having the steps of: immersing a core pin heated at 50 to 80° C. in the composition, taking the immersed core pin out of the composition, and drying a gel layer of the hypromellose acetate succinate formed on the taken-out core pin.