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公开(公告)号：US20130214776A1
公开(公告)日：2013-08-22
申请号：US13398496
申请日：2012-02-16
申请人： Perry Holman , Aravind Padmanabhan
发明人： Perry Holman , Aravind Padmanabhan
IPC分类号： G01R33/09
CPC分类号： G01R33/098 , G01R33/09
摘要： A sensing device exhibits a tunneling magneto-resistive (TMR) effect, and changes electrical resistance in response to a magnetic field. A first current carrying conductor is positioned in proximity to the TMR sensing device, such that upon an application of a sufficient current, a magnetic field is generated. The magnetic field is sufficiently strong and properly oriented so as to cause a magnetization of a soft magnetic layer of the TMR sensing device, thereby causing a change of the TMR sensing device from one bi-stable state to another bi-stable state.
摘要翻译： 感测装置呈现隧道磁阻（TMR）效应，并响应于磁场改变电阻。 第一载流导体位于TMR感测装置附近，使得在施加足够的电流时，产生磁场。 磁场足够强并且被适当地定向以便引起TMR感测装置的软磁性层的磁化，从而导致TMR感测装置从一个双稳态到另一个双稳态的改变。
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公开(公告)号：US08394644B2
公开(公告)日：2013-03-12
申请号：US11983255
申请日：2007-11-08
申请人： Yuandong Gu , Wei Yang , Aravind Padmanabhan
发明人： Yuandong Gu , Wei Yang , Aravind Padmanabhan
CPC分类号： F04B19/006 , A61M5/1486 , F04B17/00 , Y10T436/11 , Y10T436/25 , Y10T436/2575
摘要： A micro-fluidic osmotic pump capable of delivering a desired fluid at a predetermined destination comprising an inside fluid reservoir housing a compressible sac, a surrounding compartment having an external surface made up of a semi-permeable membrane and a fluid duct. The inside fluid reservoir houses a compressible sac containing a predetermined amount of a fluid that is desired to be pumped to a predetermined destination. The surrounding compartment holds a desired osmotic agent and its saturated solution in the remaining volume thereof. The surrounding compartment has an outer surface made up of a semi-permeable membrane that allows a predetermined second external fluid to permeate into the surrounding compartment. The fluid duct is substantially housed within the inside fluid reservoir and runs through openings and respectively provided through the inside fluid reservoir and the surrounding compartment.
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公开(公告)号：US08361410B2
公开(公告)日：2013-01-29
申请号：US11428332
申请日：2006-06-30
IPC分类号： G01N21/00
CPC分类号： B01L3/502746 , B01L3/50273 , B01L9/527 , B01L2200/14 , B01L2200/146 , B01L2200/147 , B01L2300/14 , B01L2300/1838 , B01L2400/0487 , B01L2400/082 , G01N15/1484 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1486
摘要： A hematology analyzer or cytometer cartridge system having flow metering. It may have on- or off-cartridge flow metering and control. The system may have local and direct flow measurement to provide accurate counts per unit volume. There may be numerous arrangements for fluidic circuit checks of the cartridge. Examples may include checks pertaining to zero flow, interface, pressure, flow rate, fluid type and quality, backflow, dry qualification, temperature exposure limits, and so on, of the circuits and cartridge associated items.
摘要翻译： 具有流量计量的血液分析仪或血细胞计数器系统。 它可以具有开/关流量计量和控制。 该系统可以具有本地和直接流量测量，以提供每单位体积的精确计数。 可能存在许多针对盒的流体回路检查的布置。 示例可以包括关于电路和盒相关物品的零流量，界面，压力，流速，流体类型和质量，回流，干质量鉴定，温度暴露限制等的检查。
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公开(公告)号：US08273294B2
公开(公告)日：2012-09-25
申请号：US11428370
申请日：2006-06-30
CPC分类号： G01N15/1484 , B01L3/502715 , B01L3/502776 , B01L2200/0621 , B01L2200/0636 , B01L2200/12 , B01L2300/087 , B01L2300/0877 , G01N15/1404 , G01N2015/008 , G01N2015/1486 , Y10T436/117497 , Y10T436/2575
摘要： A microfluidic circuit cartridge having 3-D hydrodynamic focusing. The cartridge may be fabricated with injection-molded or other molded layers providing a 3-D structure. A flow channel on the card may have a sample core flowing in a fluid of a flow channel for analysis. The sample core may be adjustable in position within the channel with one or more jets or channels of fluid being injected into the flow channel. The jets may also adjust the size of the sample core. There may be a hemoglobin measurement mechanism or card with a cuvette.
摘要翻译： 具有3-D流体动力学聚焦的微流体电路盒。 盒可以用提供3-D结构的注射成型或其它模制层制造。 卡上的流动通道可以具有在流动通道的流体中流动的样本核心用于分析。 样品芯可以在通道内的位置可调节，其中一个或多个喷射流体或通道的流体被注入到流动通道中。 射流也可以调节样品芯的尺寸。 可能有一个血红蛋白测量机制或一个有比色皿的卡。
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75.发明授权Microfluidic cartridge with reservoirs for increased shelf life of installed reagents 有权具有储存器的微流控筒，以提高安装试剂的保质期公开(公告)号：US08097225B2
公开(公告)日：2012-01-17
申请号：US10900887
申请日：2004-07-28
IPC分类号： G01N21/00
CPC分类号： B41J2/17513 , B01L3/502707 , B01L2200/16 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , B01L2300/165 , B01L2400/06
摘要： A microfluidic cartridge that includes at least one reservoir for storing a reagent or the like for an extended period of time. In one illustrative embodiment, at least part of a wall of a reservoir includes a hydrophobic material, such as a polymonochlorotrifluoroethylene (PCTFE) homopolymer and/or copolymer. The hydrophobic material may help reduce leaching, evaporation, diffusion and/or other transfer of the reagent or one of its components from the reservoir. When the reagent or the like is lyophilized, the hydrophobic material may help keep water, water vapor and/or other gases or liquids from entering the reservoir prior to use of the microfluidic cartridge.
摘要翻译： 一种微流体盒，其包括用于长时间存储试剂等的至少一个贮存器。 在一个示例性实施方案中，储存器的壁的至少一部分包括疏水性材料，例如聚单氯三氟乙烯（PCTFE）均聚物和/或共聚物。 疏水性材料可以帮助减少试剂或其一种组分从贮存器的浸出，蒸发，扩散和/或其它转移。 当试剂等被冻干时，在使用微流控盒之前，疏水材料可以帮助保持水，水蒸气和/或其它气体或液体不会进入储存器。
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公开(公告)号：US20120003730A1
公开(公告)日：2012-01-05
申请号：US13220449
申请日：2011-08-29
IPC分类号： C12M1/34
CPC分类号： B01L3/502715 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/146 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0487 , G01N15/1484 , G01N35/00722 , G01N2015/0073 , G01N2015/0084 , G01N2015/0088 , G01N2015/1413 , G01N2015/1486 , G01N2035/00891
摘要： A sample analyzer cartridge for use at a point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.
摘要翻译： 在患者的护理点使用的样品分析器盒，例如在医生的办公室，家庭或现场的其他地方。 通过提供具有所有需要的试剂和/或流体的可拆卸和/或一次性的筒，样品分析仪可以在实验室环境之外被可靠地使用，很少或没有专门的培训。
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公开(公告)号：US20100014068A1
公开(公告)日：2010-01-21
申请号：US12572694
申请日：2009-10-02
CPC分类号： G01N15/1404 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150274 , A61B5/150343 , A61B5/150351 , A61B5/157 , A61B5/417 , A61B5/7264 , B01L3/5027 , G01B11/272 , G01N15/1434 , G01N15/1459 , G01N15/1484 , G01N33/5094 , G01N33/569 , G01N35/085 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0238 , G01N2015/1075 , G01N2015/1486 , Y10T436/24
摘要： A system for scattered light and simultaneous multi-color (e.g., greater than sixteen colors) fluorescence light detecting, and for analyzing, classifying and identifying biological particles and items of interest. A sample to be tested may be entered in a disposable microfluidic cartridge which in turn is insertable in a portable, hand-holdable, or wearable miniaturized cytometer instrument. The present system may be incorporated in the cytometer instrument. It may have significant application relative to biological warfare, environmental substances, the medical field and other fields.
摘要翻译： 用于散射光和同时多色（例如，大于十六种颜色）荧光检测的系统，并用于分析，分类和识别生物颗粒和感兴趣的物品。 待测试的样品可以输入到一次性微流控盒中，该滤芯又可插入便携式，手持式或可穿戴式小型化的细胞仪器中。 本系统可以并入细胞仪器中。 相对于生物战，环境物质，医疗领域等领域可能有重大应用。
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公开(公告)号：US07641856B2
公开(公告)日：2010-01-05
申请号：US10908461
申请日：2005-05-12
CPC分类号： G01N15/1404 , G01N2015/1413 , G01N2015/1486 , Y10T436/101666
摘要： A sample analyzer with a removable and/or disposable cartridge for use at the point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.
摘要翻译： 具有可拆卸和/或一次性药筒的样品分析器，用于患者的护理点，例如在医生的办公室，家庭或现场的其他地方。 通过提供具有所有需要的试剂和/或流体的可拆卸和/或一次性的筒，样品分析仪可以在实验室环境之外被可靠地使用，很少或没有专门的培训。
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公开(公告)号：US07471394B2
公开(公告)日：2008-12-30
申请号：US11027134
申请日：2004-12-30
IPC分类号： G01J4/00
CPC分类号： G01N15/1404 , A61B5/150022 , A61B5/150213 , A61B5/150221 , A61B5/150343 , A61B5/150351 , A61B5/157 , A61B5/7264 , G01N15/1459 , G01N2015/008 , G01N2015/1486
摘要： An optical detection system for use in flow cytometry or the like, which includes a polarizing beamsplitter 820 such as a Wollaston prism. A light source provides an input light beam to a flow stream, wherein the input light beam has a polarization direction. The particles in the flow stream may produce an output light beam that includes a polarized component and a depolarized component. The polarizing beamsplitter receives the output light beam, and provides a polarized light beam and a depolarized light beam to a pair of detectors. The pair of detectors provide a first output signal that corresponds to the polarized light beam and a second output signal that corresponds to the depolarized light beam. A controller or processor may use the first output signal and the second output signal to help identify/classify particles and/or particle characteristics in the flow stream.
摘要翻译： 一种用于流式细胞仪等的光学检测系统，其包括诸如Wollaston棱镜的偏振分束器820。 光源向流动流提供输入光束，其中输入光束具有偏振方向。 流动流中的颗粒可以产生包括偏振分量和去极化分量的输出光束。 偏振分束器接收输出光束，并将偏振光束和去极化光束提供给一对检测器。 这对检测器提供对应于偏振光束的第一输出信号和对应于去偏振光束的第二输出信号。 控制器或处理器可以使用第一输出信号和第二输出信号来帮助识别/分类流动流中的粒子和/或粒子特征。
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公开(公告)号：US20080268298A1
公开(公告)日：2008-10-30
申请号：US11761290
申请日：2007-06-11
CPC分类号： H01G9/155 , H01G9/058 , H01G9/28 , H01M4/8626 , H01M8/0247 , H01M8/04201 , H01M8/1004 , H01M8/1048 , H01M16/003 , H01M2008/1095 , Y02E60/13
摘要： A power generator includes a hydrogen producing fuel and a fuel cell stack layer that includes a proton exchange membrane. An anode layer and a cathode layer are disposed on opposite surfaces of the fuel cell stack. A capacitor layer is integrated with the other layers and electrically coupled to the anode layer and the cathode layer.
摘要翻译： 发电机包括产氢燃料和包含质子交换膜的燃料电池堆层。 阳极层和阴极层设置在燃料电池堆的相对表面上。 电容器层与其它层集成并电耦合到阳极层和阴极层。
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