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    4-membered ring compound and optical phase optical retardation plate using the same
    71.
    发明授权
    4-membered ring compound and optical phase optical retardation plate using the same 有权
    4元环化合物和使用其的光学相位光学延迟板

    公开(公告)号：US06811833B2

    公开(公告)日：2004-11-02

    申请号：US10244404

    申请日：2002-09-17

    申请人： Naoyuki Nishikawa ,  Kentaro Toyooka

    发明人： Naoyuki Nishikawa ,  Kentaro Toyooka

    IPC分类号： C09K1952

    CPC分类号： C07C237/24 ,  C07C62/34 ,  C07C69/757 ,  C07C69/76 ,  C07C235/40 ,  C07C237/42 ,  C07C323/62 ,  C07C327/24 ,  C07C327/26 ,  C07C327/28 ,  C07C2601/04 ,  C07C2601/14 ,  C07D333/20 ,  C07D333/38 ,  Y10T428/10

    摘要： A 4-membered compound is represented by the following formula (I) is disclosed (in the formula, X1 and X2 each independently represent an oxygen atom, a sulfur atom or a substituted or unsubstituted imino group, Y1 and Y2 each independently represent a single bond, an oxygen atom or a substituted or unsubstituted imino group, B1 and B2 each independently represent an optionally substituted aliphatic, aliphatic carbonyl, aromatic or aromatic carbonyl group having 1-20 carbon atoms, and A1 and A2 each independently represent a group represented by the following formula (II) (Ar1, Ar2 and Ar3 each independently represent a cyclic group having 5-14 carbon atoms, L1 and L2 each independently represent a single bond or a divalent linking group, and p represents an integer of 0-2)). There is also disclosed a birefringence medium containing a 4-membered compound represented by the formula (I) and an optical element comprising the birefringence medium.

    摘要翻译： 公开了下式（I）表示的4元化合物（式中，X 1和X 2各自独立地表示氧原子，硫原子或取代或未取代的亚氨基， 1＆gt;和Y 2各自独立地表示单键，氧原子或取代或未取代的亚氨基，B 1和B 2各自独立地表示任选取代的脂族，脂族羰基，芳族或芳族羰基 具有1-20个碳原子，并且A 1和A 2各自独立地表示由下式（II）表示的基团（Ar 1，Ar 2和Ar 3）各自独立地表示环状 具有5-14个碳原子的基团，L 1和L 2各自独立地表示单键或二价连接基团，p表示0-2的整数））。 还公开了含有由式（I）表示的4元化合物和包含双折射介质的光学元件的双折射介质。

    3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation
    72.
    发明授权
    3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation 有权
    3-氨基-2-巯基苯甲酸衍生物及其制备方法

    公开(公告)号：US06498265B2

    公开(公告)日：2002-12-24

    申请号：US09963046

    申请日：2001-09-25

    申请人： Walter Kunz ,  Beat Jau

    发明人： Walter Kunz ,  Beat Jau

    IPC分类号： C07C32700

    CPC分类号： C07D285/14 ,  C07C323/63 ,  C07C327/26 ,  C07C335/22 ,  C07D277/82

    摘要： Compounds of the formula I and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III In the compounds of the formulae I and III: X is halogen, n is 0,1,2 or 3; Z is CN, CO—A or CS—A, A is hydrogen, halogen, OR1, SR2 and N(R3)R4; R1 to R4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or R3 and R4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O, S and/or N. Processes for the preparation of compounds of the formula I are described.

    摘要翻译： 式I及其二硫化物及其盐的化合物是制备具有式III的杀微生物和植物免疫作用的化合物的重要的中间产物。在式I和III的化合物中：X为卤素，n为0,1 ，2或3; Z是CN，CO-A或CS-A，A是氢，卤素，OR1，SR2和N（R3）R4; R1至R4是氢，取代或未取代的开链，饱和或 含有不超过8个碳原子的不饱和烃基，取代或未取代的含有不超过10个碳原子的环状，饱和或不饱和烃基，取代或未取代的苄基或苯乙基，取代或未取代的含有不超过8个碳原子的烷酰基 取代或未取代的苯甲酰基或取代或未取代的杂环基; 或R 3和R 4与它们所键合的氮原子一起是具有1-3个杂原子O，S和/或N的5或6元取代或未取代的杂环基。 描述了式I。

    Ortho-diphenol compounds, methods and pharmaceutical compositions for inhibiting parp
    73.
    发明申请
    Ortho-diphenol compounds, methods and pharmaceutical compositions for inhibiting parp 审中-公开
    邻苯二酚化合物，用于抑制parp的方法和药物组合物

    公开(公告)号：US20010020013A1

    公开(公告)日：2001-09-06

    申请号：US09745858

    申请日：2000-12-26

    申请人： GUILFORD PHARMACEUTICALS, INC.

    发明人： Jie Zhang ,  Larisa E. Serdyuk ,  Jia-He Li

    IPC分类号： A61K031/655 ,  A61K031/40

    CPC分类号： C07C327/26 ,  C07C69/017

    摘要： This invention relates to compounds, pharmaceutical compositions, and methods of using compounds of the formula; 1 A is O or S; R is C1-C10 straight or branched chain alkyl, C2-C10 straight or branched chain alkenyl, C2-C10 straight or branched chain alkynyl, aryl, heteroaryl, carbocycle, or heterocycle; D is a bond, or a C1-C3 straight or branched chain alkyl, C2-C3 straight or branched chain alkenyl, C2-C3 straight or branched chain alkynyl, wherein any of the carbon atoms of said alkyl, alkenyl, or alkynyl of D are optionally replaced with oxygen, nitrogen, or sulfur; and X is aryl, heteroaryl, carbocycle, or heterocycle.

    摘要翻译： 本发明涉及化合物，药物组合物和使用下式的化合物的方法： A是O或S; R是C1-C10直链或支链烷基，C2-C10直链或支链烯基，C2-C10直链或支链炔基，芳基，杂芳基，碳环或杂环; D是键或C1-C3直链或支链烷基，C2-C3直链或支链烯基，C2-C3直链或支链炔基，其中所述D的所述烷基，链烯基或炔基的任何碳原子 任选地被氧，氮或硫取代; X是芳基，杂芳基，碳环或杂环。

    Polysulfide derivatives
    77.
    发明授权
    Polysulfide derivatives 失效
    多硫化物衍生物

    公开(公告)号：US5359003A

    公开(公告)日：1994-10-25

    申请号：US104681

    申请日：1993-08-11

    申请人： Gerhard Horpel ,  Karl-Heinz Nordsiek

    发明人： Gerhard Horpel ,  Karl-Heinz Nordsiek

    IPC分类号： C07C327/36 ,  C07C327/26 ,  C08G75/14 ,  C08K5/36 ,  C08K5/38 ,  C08L21/00 ,  C08F8/00

    CPC分类号： C08K5/38 ,  C07C327/26 ,  C08G75/14 ,  C08L21/00

    摘要： Polysulfide derivatives, having the general formula (A--S--S--).sub.2 X--S--S--A processes for their production and their use for crosslinking of reversion-stable rubber vulcanizates are provided. Crosslinking with reduced reversion and loss of elastomeric properties with age is achieved by the crosslinking system provided by the invention.

    摘要翻译： 提供了具有通式（A-S-S-）2 X-S-S-A的制备方法及其用于交联反转稳定的橡胶硫化橡胶的多硫化物衍生物。 通过本发明提供的交联体系实现了具有降低的回复和随着年龄的弹性体特性损失的交联。

    Optically active compound and liquid crystal composition containing same
    79.
    发明授权
    Optically active compound and liquid crystal composition containing same 失效
    含有其的光学活性化合物和液晶组合物

    公开(公告)号：US4816178A

    公开(公告)日：1989-03-28

    申请号：US42814

    申请日：1987-04-27

    申请人： Kazuharu Katagiri ,  Kenji Shinjo ,  Kazuo Yoshinaga

    发明人： Kazuharu Katagiri ,  Kenji Shinjo ,  Kazuo Yoshinaga

    IPC分类号： C07C327/26 ,  C09K19/28 ,  C09K19/58 ,  C09K19/52 ,  C09K19/06 ,  C09K19/12

    CPC分类号： C07C327/26 ,  C09K19/28 ,  C09K19/58 ,  C09K19/586

    摘要： An optically active 4-alkylbenzenethiol and an optically active bis(4-alkylphenyl)disulfide represented by the formula: ##STR1## respectively, wherein R.sub.1 * and R.sub.2 * are respectively an alkyl group having 4-12 carbon atoms including an asymmetric carbon atom, may be prepared, e.g., through halogenation or sulfonation of an optically active alcohol, followed by reaction with a phenylmagnesium halide, chlorosulfonylation and reduction. The optically active thiol or disulfide is effective, e.g., in preventing occurrence of reverse domain when added to a nematic liquid crystal, and also can be bonded to an intermediate to provide a functional material including a mesomorphic compound represented by the formula: ##STR2## wherein R.sub.3 is an alkyl or alkoxy group having 1-18 carbon atoms, n is 1 or 2, and C* is an asymmetric carbon atom.

    摘要翻译： 分别由下式表示的光学活性4-烷基苯硫酚和光学活性双（4-烷基苯基）二硫化物：其中R1 *和R2 *分别是具有4-12个碳原子的烷基，包括 不对称碳原子，可以通过例如通过光学活性醇的卤化或磺化，然后与苯基卤化镁反应，氯磺酰化和还原来制备。 光学活性硫醇或二硫化物是有效的，例如在加入向列型液晶时防止反向结构域的发生，并且还可以与中间体结合，从而提供包括由下式表示的介晶化合物的功能材料：＆lt; IMAGE＆gt; 其中R3是具有1-18个碳原子的烷基或烷氧基，n是1或2，C *是不对称碳原子。