Droplet Actuator Loading and Target Concentration
    84.
    发明申请
    Droplet Actuator Loading and Target Concentration 审中-公开
    液滴致动器装载和目标浓度

    公开(公告)号:US20130146461A1

    公开(公告)日:2013-06-13

    申请号:US13686495

    申请日:2012-11-27

    IPC分类号: C25B15/00

    摘要: A droplet actuator and method of providing a droplet comprising an target substance on the droplet actuator, and including discrete flow and continuous flow functionality. Discrete flow function is controlled by electrodes arranged for conducting droplet operations on a substrate surface. The continuous flow function includes a fluid path arranged for flowing a fluid therethrough. The discrete flow and continuous flow functions may be by a barrier, including a second fluid path through the barrier. The continuous flow function may include a capture surface comprising a component having an affinity for the target substance. Methods of the invention may include flowing a fluid comprising the target substance through the fluid path; capturing the target substance on the capture surface; and forming a droplet in the discrete flow region via the second fluid path and the electrodes comprising the captured target substance.

    摘要翻译: 液滴致动器和在液滴致动器上提供包含目标物质的液滴的方法,并且包括离散流动和连续流动功能。 离散流动功能由布置用于在基板表面上进行液滴操作的电极控制。 连续流动功能包括设置成使流体流过其中的流体路径。 离散的流动和连续流动功能可以是通过屏障,包括通过屏障的第二流体路径。 连续流动功能可以包括包含对目标物质具有亲和性的成分的捕获表面。 本发明的方法可以包括使包含目标物质的流体流过流体路径; 捕获表面上的目标物质; 以及经由所述第二流体路径在所述离散流动区域中形成液滴,并且所述电极包括所捕获的目标物质。

    DROPLET-BASED NUCLEIC ACID AMPLIFICATION METHOD AND APPARATUS
    86.
    发明申请
    DROPLET-BASED NUCLEIC ACID AMPLIFICATION METHOD AND APPARATUS 有权
    基于滴液的核酸放大方法和装置

    公开(公告)号:US20130092539A1

    公开(公告)日:2013-04-18

    申请号:US13680979

    申请日:2012-11-19

    IPC分类号: G01N27/447

    摘要: Aspects of embodiments of the invention relate to a simulator including a visual display capable of outputting to a user a display one or more effects of a command series selected and a system including a droplet microactuator electronically coupled to and controlled by a processor capable of executing instructions, the droplet microactuator including a substrate comprising electrodes for conducting droplet operations. Further aspects of embodiments of the invention relate to a droplet operations troubleshooting apparatus. Other aspects of embodiments of the invention relate to a computer implemented method of displaying simulated microactuator droplets.

    摘要翻译: 本发明的实施例的方面涉及一种模拟器,其包括能够向用户输出显示所选择的命令序列的一个或多个效果的视觉显示器,以及包括电子耦合到能够执行指令的处理器并由其控制的液滴微致动器的系统 液滴微致动器包括包括用于进行液滴操作的电极的基板。 本发明的实施例的其它方面涉及一种液滴操作故障排除装置。 本发明的实施例的其他方面涉及一种显示模拟微致动器液滴的计算机实现的方法。

    Droplet actuator loading and target concentration
    88.
    发明授权
    Droplet actuator loading and target concentration 有权
    液滴致动器负载和目标浓度

    公开(公告)号:US08317990B2

    公开(公告)日:2012-11-27

    申请号:US12531835

    申请日:2008-03-24

    IPC分类号: G01N35/08 G01N33/543

    摘要: A droplet actuator and method of providing a droplet comprising an target substance on the droplet actuator, and including discrete flow and continuous flow functionality. Discrete flow function is controlled by electrodes arranged for conducting droplet operations on a substrate surface. The continuous flow function includes a fluid path arranged for flowing a fluid therethrough. The discrete flow and continuous flow functions may be by a barrier, including a second fluid path through the barrier. The continuous flow function may include a capture surface comprising a component having an affinity for the target substance. Methods of the invention may include flowing a fluid comprising the target substance through the fluid path; capturing the target substance on the capture surface; and forming a droplet in the discrete flow region via the second fluid path and the electrodes comprising the captured target substance.

    摘要翻译: 液滴致动器和在液滴致动器上提供包含目标物质的液滴的方法,并且包括离散流动和连续流动功能。 离散流动功能由布置用于在基板表面上进行液滴操作的电极控制。 连续流动功能包括设置成使流体流过其中的流体路径。 离散的流动和连续流动功能可以是通过屏障,包括通过屏障的第二流体路径。 连续流动功能可以包括包含对目标物质具有亲和性的成分的捕获表面。 本发明的方法可以包括使包含目标物质的流体流过流体路径; 捕获表面上的目标物质; 以及经由所述第二流体路径在所述离散流动区域中形成液滴,并且所述电极包括所捕获的目标物质。