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公开(公告)号：US07022284B2
公开(公告)日：2006-04-04
申请号：US10434887
申请日：2003-05-09
申请人： Ben F. Brian , John Thomas Buckley , Jean-Pierre Dueri , Mehrdad Farhangnia , Steven K. Stringer
发明人： Ben F. Brian , John Thomas Buckley , Jean-Pierre Dueri , Mehrdad Farhangnia , Steven K. Stringer
CPC分类号： A61M1/1698 , A61M1/262 , A61M1/267 , A61M2205/502 , A61M2205/505 , A61M2209/084 , B01D19/0031 , Y10S128/03 , Y10S261/28
摘要： Apparatus for oxygenating and pumping blood includes a housing defining a blood flow path including, in series, a gas collection plenum, a pump space and a blood oxygenation element. A pump disposed in the pump space is configured to draw blood from the gas collection plenum and propel blood from the pump space through a heat exchanger and the blood oxygenation element. The heat exchanger includes a heat exchange plate and a coolant space.
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公开(公告)号：US07022099B2
公开(公告)日：2006-04-04
申请号：US10392441
申请日：2003-03-17
申请人： A. Kenneth Litzie , Steven K. Stringer , Mehrdad Farhangnia , Muslim Tyebjee , Thomas A. Afzal , Ben F. Brian, III
发明人： A. Kenneth Litzie , Steven K. Stringer , Mehrdad Farhangnia , Muslim Tyebjee , Thomas A. Afzal , Ben F. Brian, III
CPC分类号： A61M1/3629 , A61M1/1006 , A61M1/101 , A61M1/1029 , A61M1/1086 , A61M2027/004 , A61M2205/33 , A61M2205/3303 , A61M2205/3334 , Y10S128/03
摘要： Apparatus for processing blood in an extracorporeal circuit with automatic flow control is provided in which error conditions are sensed and system operation is modulated responsive to the error conditions. The apparatus includes an extracorporeal blood processing system, at least one sensor that senses the presence or absence of gas or monitors venous pressure, and a controller operably coupled to the blood processing system to selectively reduce pump speed or to reconfigure flow paths within the blood processing system responsive to the sensor output.
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3.发明授权公开(公告)号：US06773670B2
公开(公告)日：2004-08-10
申请号：US10067434
申请日：2002-02-05
申请人： Steven K. Stringer , Kevin L. Hultquist , Mehrdad Farhangnia , Fred I. Linker , Ben F. Brian, III
发明人： Steven K. Stringer , Kevin L. Hultquist , Mehrdad Farhangnia , Fred I. Linker , Ben F. Brian, III
IPC分类号： A61M136
CPC分类号： A61M1/3626 , A61M1/1006 , A61M1/101 , A61M1/262 , A61M1/267 , A61M1/3606 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3666 , Y10S128/03 , Y10S261/28 , Y10S417/902
摘要： Apparatus and methods for removing gas from a blood handling system. A filter apparatus for monitoring and removing gas is provided comprising of a gas removal/blood filter, a sensor to sense the presence of gas, and a valve operably coupled to the sensor to evacuate gas from the apparatus when the sensor detects an accumulation of gas. When used with a previously known blood handling system, the present filter apparatus facilitates priming and the addition of additional blood handling elements during operation of the blood handling system.
摘要翻译： 从血液处理系统中除去气体的装置和方法。 提供了一种用于监测和去除气体的过滤装置，其包括气体去除/血液过滤器，用于感测气体存在的传感器，以及可操作地耦合到传感器的阀，当传感器检测到气体的积聚时，从装置排出气体 。 当与先前已知的血液处理系统一起使用时，本过滤装置有利于在血液处理系统的操作期间起动和添加额外的血液处理元件。
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公开(公告)号：US06689315B2
公开(公告)日：2004-02-10
申请号：US10117964
申请日：2002-04-05
IPC分类号： A61M136
CPC分类号： A61M1/3626 , A61M1/1006 , A61M1/101 , A61M1/262 , A61M1/267 , A61M1/3606 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3666 , Y10S128/03 , Y10S261/28 , Y10S417/902
摘要： Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system and a pump impeller with a single piece metal insert. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.
摘要翻译： 提供了用于泵送和充氧血液的装置和方法，其包括气体去除系统和具有单件金属插入件的泵叶轮。 提供了一种集成血液处理单元，其中气体去除/血液过滤器，泵和血氧元件安装在公共壳体内。 气体去除系统包括安装在壳体上以感测气体存在的传感器，并且当传感器检测到气体积聚时，阀可操作地耦合到传感器以从系统排出气体。
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5.发明授权Anion exchange materials comprised of derivatized cellulose-polyester composites 失效由衍生的纤维素 - 聚酯复合材料组成的阴离子交换材料
公开(公告)号：US5354472A
公开(公告)日：1994-10-11
申请号：US981912
申请日：1992-11-23
IPC分类号： G01N30/00 , A61M1/36 , B01D15/08 , B01J20/26 , B01J20/28 , B01J20/281 , B01J20/285 , B01J20/32 , B01J41/12 , B01J41/16 , C08J5/22 , D04H1/44 , D04H1/46 , G01N30/88 , C02J5/20
CPC分类号： C08J5/2275 , A61M1/3675 , B01J41/16 , B01J41/20 , C08J5/2212 , D04H1/44 , D04H1/46 , C08J2301/08 , C08J2435/02
摘要： A novel biocompatible anion exchange membrane is prepared by reacting the hydroxyl groups of a chromatographic support material with a polyester-cellulose solution containing glycidyl trimethyl ammonium chloride and bis glycidyl polyethylene oxide.
摘要翻译： 通过使色谱载体材料的羟基与含有缩水甘油基三甲基氯化铵和双缩水甘油基聚环氧乙烷的聚酯 - 纤维素溶液反应来制备新的生物相容性阴离子交换膜。
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公开(公告)号：US09364246B2
公开(公告)日：2016-06-14
申请号：US13533745
申请日：2012-06-26
IPC分类号： A61B17/32 , A61B17/3209 , A61B18/18 , A61N1/30 , A61B18/20 , A61B17/3201 , A61B18/14 , A61B17/00 , A61B17/30 , A61B17/34 , A61B18/00 , A61B19/00 , A61H23/02 , A61N1/32 , A61N1/40 , A61N7/02 , A61N7/00
CPC分类号： A61B17/32093 , A61B17/00 , A61B17/32 , A61B17/320016 , A61B17/32002 , A61B17/3201 , A61B18/1402 , A61B18/1477 , A61B18/18 , A61B18/20 , A61B2017/00119 , A61B2017/00747 , A61B2017/00761 , A61B2017/308 , A61B2017/320028 , A61B2017/32004 , A61B2017/320052 , A61B2017/320056 , A61B2017/32006 , A61B2017/3405 , A61B2017/3407 , A61B2018/0016 , A61B2018/00291 , A61B2018/00452 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/143 , A61B2018/1432 , A61B2090/0811 , A61B2090/0815 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61H23/0245 , A61H2201/0207 , A61H2201/10 , A61H2201/105 , A61H2207/00 , A61N1/306 , A61N1/327 , A61N1/328 , A61N1/403 , A61N7/02 , A61N2007/0008
摘要： A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
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7.发明授权Fluid-jet dissection system and method for reducing the appearance of cellulite 有权流体喷射解剖系统和减少脂肪团外观的方法公开(公告)号：US09358033B2
公开(公告)日：2016-06-07
申请号：US12787377
申请日：2010-05-25
申请人： Sowmya Ballakur , Robert L. Clark, III , James E. Chomas , Ben F. Brian, III , David M. Clapper
发明人： Sowmya Ballakur , Robert L. Clark, III , James E. Chomas , Ben F. Brian, III , David M. Clapper
CPC分类号： A61B17/3203 , A61B17/00234 , A61B18/20 , A61B2017/00747 , A61B2017/306 , A61B2017/32035 , A61B2018/00452 , A61B2217/005 , A61M5/28 , A61M5/3007 , A61N2007/0008
摘要： A minimally invasive skin treatment system includes a platform having a recessed area on its bottom and one or more injection ports orthogonal to its top, each injection port including a through-hole to the recessed area. The system includes an injection device including a needle slidably disposed in a selective port such that the needle passes into the recessed area and percutaneously through a dermis disposed within the recessed area. A nozzle is configured to discharge a fluid at a high pressure in a direction orthogonal to an axis of the needle and parallel to the top of the platform to cut create a plane of dissection within the subcutaneous tissue.
摘要翻译： 微创皮肤治疗系统包括其底部具有凹陷区域和与其顶部正交的一个或多个注射端口的平台，每个注射端口包括到凹陷区域的通孔。 该系统包括注射装置，其包括可滑动地设置在选择性口中的针，使得针穿过凹陷区域并经皮穿过设置在凹陷区域内的真皮。 喷嘴构造成在与针的轴线正交的方向上以高压排出流体，并且平行于平台的顶部切割，从而在皮下组织内产生解剖平面。
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公开(公告)号：US08439940B2
公开(公告)日：2013-05-14
申请号：US12975966
申请日：2010-12-22
IPC分类号： A61B17/32
CPC分类号： A61M1/0039 , A61B17/00234 , A61B17/30 , A61B17/320016 , A61B17/320725 , A61B17/32075 , A61B18/14 , A61B2017/00747 , A61B2017/308 , A61B2018/0022 , A61B2018/00464 , A61B2018/00589 , A61B2018/00601 , A61B2018/1425 , A61B2018/1467 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61M1/008
摘要： A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.
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公开(公告)号：US20110022136A1
公开(公告)日：2011-01-27
申请号：US12897637
申请日：2010-10-04
申请人： David J. Scott , Ben F. Brian , Lloyd F. Wright , Leo A. Chin , Edward W. Hollmen , Daniel W. Seegars , Mark A. Logan
发明人： David J. Scott , Ben F. Brian , Lloyd F. Wright , Leo A. Chin , Edward W. Hollmen , Daniel W. Seegars , Mark A. Logan
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F2007/0054 , A61F2007/0093 , A61F2007/0095 , A61F2007/126 , A61M1/369 , A61M2205/3372 , F28D2021/005 , F28F2280/02
摘要： Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. The control unit includes a heater/cooler device for providing heated or cooled fluid to a heat exchanger in thermal communication with the fluid heat exchange medium circulating to the heat exchange catheter, a user input device, and a processor connected to receive input from various sensors around the body and the system. A temperature control scheme for ramping the body temperature up or down without overshoot is provided.
摘要翻译： 包括诱导低温的状态的患者的温度改变方法和装置，或其选定区域。 使用在其中流体热交换介质循环的内部热交换导管来实现温度改变。 热交换盒附接到导管的循环导管，热交换盒的尺寸设计成与控制单元内的空腔接合。 控制单元包括加热器/冷却器装置，用于将热或冷却的流体提供给与循环到热交换导管的流体热交换介质热连通的热交换器，用户输入装置和连接以从各种传感器接收输入的处理器 围绕身体和系统。 提供了一种用于使体温上升或下降而没有过冲的温度控制方案。
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10.发明申请公开(公告)号：US20100228182A1
公开(公告)日：2010-09-09
申请号：US12787382
申请日：2010-05-25
CPC分类号： A61B17/32093 , A61B17/00 , A61B17/32 , A61B17/320016 , A61B17/32002 , A61B17/3201 , A61B18/1402 , A61B18/1477 , A61B18/18 , A61B18/20 , A61B2017/00119 , A61B2017/00747 , A61B2017/00761 , A61B2017/308 , A61B2017/320028 , A61B2017/32004 , A61B2017/320052 , A61B2017/320056 , A61B2017/32006 , A61B2017/3405 , A61B2017/3407 , A61B2018/0016 , A61B2018/00291 , A61B2018/00452 , A61B2018/00702 , A61B2018/00791 , A61B2018/00875 , A61B2018/143 , A61B2018/1432 , A61B2090/0811 , A61B2090/0815 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61H23/0245 , A61H2201/0207 , A61H2201/10 , A61H2201/105 , A61H2207/00 , A61N1/306 , A61N1/327 , A61N1/328 , A61N1/403 , A61N7/02 , A61N2007/0008
摘要： A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
摘要翻译： 提供皮肤病治疗装置。 该装置包括一个手持件和一个切割工具，其中工具插入通过导管并经皮地插入设置在手持件的凹进区域内的组织中。 该装置和方法切割皮肤下的纤维结构，其以基本上平行于皮肤表面的角度引起脂肪团，并通过将高度纤维状网状物通过单个针孔部署来形成非脂肪团形成结构来代替这些结构，以产生 高度纤维层直接或通过伤口愈合过程。
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