COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK
    2.
    发明申请
    COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK 有权
    包含SIRT1表达诱发剂的组合物,用于预防或治疗食欲或分解性震动

    公开(公告)号:US20130150555A1

    公开(公告)日:2013-06-13

    申请号:US13818847

    申请日:2012-02-17

    IPC分类号: A61K38/21

    CPC分类号: A61K38/215 A61P31/04

    摘要: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.

    摘要翻译: 本发明涉及含有用于预防或治疗败血症或败血性休克的SIRT1诱导剂(沉默交配型信息调节2同系物)表达的组合物。 SIRT1表达的诱导物可以通过减少促炎细胞因子和增加抗炎细胞因子,显着降低败血症或败血性休克引起的死亡率。 因此,SIRT1表达诱导剂可用于预防或治疗败血症或败血性休克。

    PROMOTABLE INTELLIGENT DISPLAY DEVICE AND PROMOTING METHOD THEREOF
    3.
    发明申请
    PROMOTABLE INTELLIGENT DISPLAY DEVICE AND PROMOTING METHOD THEREOF 审中-公开
    可启动智能显示设备及其推广方法

    公开(公告)号:US20120146906A1

    公开(公告)日:2012-06-14

    申请号:US13390003

    申请日:2010-08-11

    申请人: Se Kyung Song

    发明人: Se Kyung Song

    IPC分类号: G06F3/033

    摘要: A promotable intelligent display device includes: an image output means outputting character and promotion images; a camera taking pictures of people; an image recognition means receiving the taken image, and outputting contextual information source among information on position of people, moving direction, distance, number, and size; a controlling means specifying a promotion target at time intervals based on the contextual information, determining driving information on the direction and speed of rotation of the image output means based on the information on moving direction and position of the promotion target, and determining promotion activities by the distance, number, and size of the promotion target; a voice output means outputting promotion and character voices based on the promotion activities; and a driving means connected with the image output means by connection shaft to enable the rotation of the image output means by controlling a shaft based on the driving information and promotion activities.

    摘要翻译: 一种可升级智能显示装置,包括:输出字符和促销图像的图像输出装置; 相机拍照人物; 图像识别装置接收所拍摄的图像,并且在人物的位置,移动方向,距离,数量和大小的信息之间输出上下文信息源; 基于上下文信息以时间间隔指定促销目标的控制装置,基于关于促销对象的移动方向和位置的信息来确定图像输出装置的旋转方向和速度的驾驶信息,并且通过以下方式确定促销活动: 晋升目标的距离,数量和大小; 语音输出意味着基于促销活动输出促销和角色声音; 以及通过连接轴与图像输出装置连接的驱动装置,以通过基于驾驶信息和促销活动来控制轴来实现图像输出装置的旋转。

    FUNCTIONAL OUTER COVER FOR FEEDING CUSHION AND FUNCTIONAL FEEDING CUSHION USING SAME

    公开(公告)号:US20220167758A1

    公开(公告)日:2022-06-02

    申请号:US17215577

    申请日:2021-03-29

    IPC分类号: A47D13/08 A47D15/00

    摘要: Provided is a functional feeding cushion, and more particularly, to a functional feeding cushion in which an outer cover to which a fixation band is coupled is used and the outer cover is used while covering a cushion body and as necessary, at least one of a striped cover, a side cushion, a lower cushion, etc., may be coupled and used. Further provided is a functional outer cover for a feeding cushion, which includes: a cover body covered as an outer cover of a feeding cushion for an infant; and a fixation band vertically disposed at the center of a front surface of the cover body on which an infant's body is placed and having upper and lower ends coupled to the cover body.

    DEVICE AND METHOD FOR INDUCING USE
    8.
    发明申请
    DEVICE AND METHOD FOR INDUCING USE 审中-公开
    用于诱导使用的装置和方法

    公开(公告)号:US20130014055A1

    公开(公告)日:2013-01-10

    申请号:US13513679

    申请日:2010-12-06

    IPC分类号: G06F3/048

    CPC分类号: G09B19/00 G06F2203/011

    摘要: The device for inducing use according to the present invention comprises an input unit for receiving user input, an event storage unit for storing a plurality of events which can be perceived by the user, an event extraction unit for extracting one of the events stored in the event storage unit if the user input is sensed at the input unit, and an event expression unit for displaying the event extracted from the event extraction unit to the user; thereby making it possible to induce the user to use the input unit in an enjoyably engaged fashion.

    摘要翻译: 根据本发明的用于诱导使用的装置包括用于接收用户输入的输入单元,用于存储可由用户感知的多个事件的事件存储单元,用于提取存储在用户输入中的事件之一的事件提取单元 如果在输入单元处感测到用户输入的事件存储单元,以及用于将从事件提取单元提取的事件显示给用户的事件表达单元; 从而能够以令人愉快的方式使用户使用输入单元。

    MARKER GENES FOR SCREENING OF DRUG-INDUCED TOXICITY IN HUMAN CELLS AND SCREENING METHOD USING THE SAME
    10.
    发明申请
    MARKER GENES FOR SCREENING OF DRUG-INDUCED TOXICITY IN HUMAN CELLS AND SCREENING METHOD USING THE SAME 审中-公开
    用于筛选人类细胞毒性诱发毒性的标记基因及其筛选方法

    公开(公告)号:US20110118127A1

    公开(公告)日:2011-05-19

    申请号:US12720134

    申请日:2010-03-09

    IPC分类号: C40B30/00 C40B40/08

    摘要: The present invention relates to a marker gene for screening a drug inducing toxicity in human and a screening method using the same. More precisely, the invention relates to a microarray on which marker genes up-or down-regulated specifically by 16 drugs inducing pulmonary toxicity, teratogenicity, nephrotoxicity, cardiotoxicity or mutation (Methotrexate, Nitrofurantoin, Amiodarone, Carbamazepine, Valproic acid, Thalidomide, Cisplatin, Gentamycin, Amphotericine, Furylfuramide, N-nitroso-N-methylurea, methylmethanesulfonate, 4-nitroquinoline-N-oxide, 2-nitrofluorene, Doxorubicin and Daunorubicin) are integrated, a kit comprising the said microarray, and a screening method of a drug inducing toxicity in human using the same. The DNA microarray containing the marker gene of the present invention facilitates the construction of Toxtarget Array for screening a drug inducing toxicity in human using drug-specific genes, suggesting that this chip can be effectively used for monitoring drugs or chemicals carrying toxicity to human or determining risks thereof and also it can be used as a tool for examining mechanisms of toxicity/side effects caused by the drugs.

    摘要翻译: 本发明涉及用于筛选诱导人体毒性的药物的标记基因和使用其的筛选方法。 更准确地说,本发明涉及一种微阵列,其上由16种药物诱导肺毒性,致畸性,肾毒性,心脏毒性或突变特异性地上调或下调的标记基因(甲氨蝶呤,呋喃妥因,胺碘酮,卡马西平,丙戊酸,沙利度胺,顺铂, 整合了庆大霉素,两性霉素,呋喃酰胺,N-亚硝基-N-甲基脲,甲基磺酸甲酯,4-硝基喹啉-N-氧化物,2-硝基芴,多柔比星和柔红霉素),包含所述微阵列的试剂盒和诱导药物的筛选方法 人体毒性相同。 含有本发明标记基因的DNA微阵列有利于构建Toxtarget Array,用于筛选使用药物特异性基因在人体中诱导毒性的药物,表明该芯片可有效用于监测对人体具有毒性或确定性的药物或化学物质 也可以作为检测药物毒性/副作用机制的工具。