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    Systems and Methods for Cooling in a Thermal Cycler
    2.
    发明申请
    Systems and Methods for Cooling in a Thermal Cycler 审中-公开
    热循环器冷却系统和方法

    公开(公告)号：US20080050781A1

    公开(公告)日：2008-02-28

    申请号：US11767327

    申请日：2007-06-22

    申请人： Mark Oldham ,  Eric Henderson ,  Vinod Mirchandani ,  Eric Nordman ,  Marc Haberstroh ,  Johannes Sluis

    发明人： Mark Oldham ,  Eric Henderson ,  Vinod Mirchandani ,  Eric Nordman ,  Marc Haberstroh ,  Johannes Sluis

    IPC分类号： C12P19/34 ,  B01J19/00 ,  C12M1/38

    CPC分类号： B01L7/52 ,  B01L2300/0636 ,  B01L2300/0829 ,  B01L2300/0877 ,  B01L2300/1822 ,  B01L2300/1844 ,  B01L2300/185

    摘要： A device for performing polymerase chain reactions using cooling members not used in conventional thermal cyclers. A device for performing polymerase chain reactions may include a sample holder configured to receive a nucleic acid sample, a heating system configured to raise the temperature of the sample, a cooling system configured to lower the temperature of the sample, and a controller configured to operably control the heating system and the cooling system to cycle the device through a desired time-temperature profile. The cooling system may comprise at least one cooling member selected from a synthetic jet ejector array, a vibration-induced droplet atomization system, a vibrating diaphragm system, a piezo fan, a Cold Gun, a microchannel cooling loop, and a Cool Chip.

    摘要翻译： 使用不用于常规热循环仪的冷却部件进行聚合酶链反应的装置。 用于进行聚合酶链式反应的装置可以包括配置成接收核酸样品的样品架，配置成提高样品温度的加热系统，配置成降低样品温度的冷却系统，以及配置成可操作地 控制加热系统和冷却系统以使设备循环所需的时间 - 温度曲线。 冷却系统可以包括选自合成射流喷射器阵列，振动诱导液滴雾化系统，振动膜系统，压电风扇，冷枪，微通道冷却回路和冷却芯片中的至少一个冷却构件。

    Device including inductively heatable fluid retainment region, and method
    3.
    发明申请
    Device including inductively heatable fluid retainment region, and method 失效
    装置包括电感可加热流体保留区域和方法

    公开(公告)号：US20070012683A1

    公开(公告)日：2007-01-18

    申请号：US11417756

    申请日：2006-05-04

    申请人： Steven Boege ,  Mark Oldham ,  Marc Haberstroh ,  Stephen Gunstream ,  Adrian Fawcett ,  Douglas Grunewald

    发明人： Steven Boege ,  Mark Oldham ,  Marc Haberstroh ,  Stephen Gunstream ,  Adrian Fawcett ,  Douglas Grunewald

    IPC分类号： H05B6/02

    CPC分类号： H05B6/108 ,  B01F13/0818 ,  B01L3/50851 ,  B01L2300/0803 ,  B01L2300/0809 ,  B01L2300/1816 ,  H05B6/109 ,  H05B2214/04 ,  Y10T137/6606

    摘要： A device is provided that comprises one or more fluid retainment regions each having at least one wall, and one or more loops in heat-transfer communication with the at least one wall. Each of the loops can comprise an electrical conductor that surrounds the same or a different fluid retainment region. A device is provided that comprises one or more fluid retainment regions each having particulates disposed therein. A system is provided that includes a platen adapted to hold a device including fluid retainment regions and one or more electrical conductors in heat-transfer communication with the fluid retainment regions. Methods of heating a sample are also provided.

    摘要翻译： 提供了一种装置，其包括一个或多个流体保持区域，每个流体保持区域各自具有至少一个壁，以及与所述至少一个壁热传递连通的一个或多个环路。 每个环可以包括围绕相同或不同流体保持区域的电导体。 提供了一种装置，其包括一个或多个流体保持区域，每个流体保持区域各自具有设置在其中的微粒。 提供了一种系统，其包括适于保持包括流体保持区域的装置和与流体保持区域传热连通的一个或多个电导体的压板。 还提供了加热样品的方法。

    CAPILLARY ELECTROPHORESIS CATHODE SYSTEMS AND METHODS
    8.
    发明公开
    CAPILLARY ELECTROPHORESIS CATHODE SYSTEMS AND METHODS 审中-公开

    公开(公告)号：US20230184714A1

    公开(公告)日：2023-06-15

    申请号：US18166745

    申请日：2023-02-09

    申请人： Marc Haberstroh ,  Geoffrey DAHLHOFF

    发明人： Marc Haberstroh ,  Geoffrey DAHLHOFF

    IPC分类号： G01N27/447 ,  G01F23/263 ,  G01R19/25

    CPC分类号： G01N27/44713 ,  G01N27/44782 ,  G01F23/263 ,  G01R19/25

    摘要： The present disclosure relates, in some embodiments, to a system for measuring capillary electrophoresis current. The system includes a plurality of capillaries, where each capillary has a cathode end and an anode end. The system further includes a plurality of cathode buffers. Each of the cathode buffers is configured to be electrically isolated from the other cathode buffers. Further, each cathode buffer is associated with one capillary of the plurality of capillaries. The cathode end of each capillary is immersed in its associated cathode buffer. The system includes a plurality of current sensors, each current sensor associated with one capillary of the plurality of capillaries for measuring current. In some embodiments, the plurality of capillaries is four capillaries.