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    Electrospray devices for mass spectrometry
    2.
    发明授权
    Electrospray devices for mass spectrometry 有权
    用于质谱的电喷雾装置

    公开(公告)号：US07060975B2

    公开(公告)日：2006-06-13

    申请号：US10982189

    申请日：2004-11-05

    申请人： Karen L. Seaward ,  Hongfeng Yin ,  Kevin P. Killeen ,  Daniel Sobek ,  Daniel Roitman

    发明人： Karen L. Seaward ,  Hongfeng Yin ,  Kevin P. Killeen ,  Daniel Sobek ,  Daniel Roitman

    IPC分类号： H01J49/10

    CPC分类号： H01J49/165

    摘要： An electrospray device for a mass spectrometry system is described. The electrospray device comprises a body portion and a tip portion extending from the body portion. The tip portion comprises a polymeric material. The electrospray device also comprises a hydrophobic coating substantially selectively covering the tip portion. The hydrophobic coating is electrically nonconductive.

    摘要翻译： 描述了用于质谱系统的电喷雾装置。 电喷雾装置包括主体部分和从主体部分延伸的尖端部分。 尖端部分包括聚合材料。 电喷雾装置还包括基本上选择性地覆盖尖端部分的疏水涂层。 疏水涂层是不导电的。

    Devices and methods for separating constituents
    6.
    发明授权
    Devices and methods for separating constituents 有权
    用于分离成分的装置和方法

    公开(公告)号：US07111501B2

    公开(公告)日：2006-09-26

    申请号：US10678332

    申请日：2003-10-03

    申请人： Roy D. Rocklin ,  Kevin P. Killeen ,  Hongfeng Yin

    发明人： Roy D. Rocklin ,  Kevin P. Killeen ,  Hongfeng Yin

    IPC分类号： G01N30/00

    CPC分类号： G01N30/34 ,  G01N30/6095 ,  G01N2030/324 ,  G01N2030/347 ,  G01N2030/645

    摘要： The subject invention includes constituent separation apparatuses that include a fluid pathway and a pair of spaced-apart electrodes positioned within the pathway for detecting current flow within a mobile phase present in the pathway. Coupled to the pair of spaced-apart electrodes is a mix ratio determinator for determining the mix ratio of the mobile phase from the detected current flow. Also provided are methods that include contacting a mobile phase with an apparatus for separating constituents of a mobile phase, detecting the current flow of the mobile phase when the mobile phase is in contact with the apparatus and determining the mix ratio of the mobile phase from the detected current flow. The mix ratio may be adjusted based on the determined mix ratio. Algorithms for practicing the subject methods are also provided on computer readable mediums. Systems and kits for practicing the subject methods are also provided.

    摘要翻译： 本发明包括构成分离装置，其包括流体通道和位于通路内的一对间隔开的电极，用于检测存在于通路中的流动相中的电流。 耦合到一对间隔开的电极是用于确定流动相与检测到的电流的混合比的混合比率确定器。 还提供了包括使流动相与用于分离流动相的组分的装置接触的方法，当流动相与装置接触时检测流动相的当前流量，并确定流动相与装置的混合比 检测电流。 可以基于所确定的混合比来调节混合比。 用于实践主题方法的算法也提供在计算机可读介质上。 还提供了用于实践主题方法的系统和套件。

    TANDEM IONIZER ION SOURCE FOR MASS SPECTROMETER AND METHOD OF USE
    8.
    发明申请
    TANDEM IONIZER ION SOURCE FOR MASS SPECTROMETER AND METHOD OF USE 有权
    用于质谱仪的串联离子源和使用方法

    公开(公告)号：US20100193702A1

    公开(公告)日：2010-08-05

    申请号：US12363685

    申请日：2009-01-30

    申请人： Gangqiang Li ,  Hongfeng Yin

    发明人： Gangqiang Li ,  Hongfeng Yin

    IPC分类号： H01J27/02 ,  H01J49/04 ,  H01J49/10 ,  H01J49/14 ,  H01J27/20

    CPC分类号： H01J49/107 ,  H01J49/165

    摘要： An ion source a first ionizer comprising: an electrospray needle comprising a tip; and a conduit disposed annularly about the needle and configured to pass an inert gas in proximity of the tip to nebulize a fluid emerging from the tip, the nebulized fluid comprising analytes and a mobile phase. The ion source comprises a capillary in tandem with the first ionizer and configured to receive the droplets; a heater configured to heat the capillary to a temperature at which mobile phase vaporizes; and a second ionizer in tandem with the capillary and configured to receive the vaporized mobile phase and the analytes. A method is also described.

    摘要翻译： 离子源，第一离子发生器，包括：电喷针，包括尖端; 以及围绕所述针环设置的导管，其被配置成使所述尖端附近的惰性气体通过，以使从所述尖端出来的流体雾化，所述雾化流体包含分析物和流动相。 离子源包括与第一离子发生器串联的毛细管并且构造成接收液滴; 加热器，被配置为将毛细管加热至流动相蒸发的温度; 以及第二离子发生器，其与所述毛细管串联并且被配置为接收蒸发的流动相和所述分析物。 还描述了一种方法。

    Incremental update of long-term and short-term user profile scores in a behavioral targeting system
    9.
    发明申请
    Incremental update of long-term and short-term user profile scores in a behavioral targeting system 有权
    在行为定位系统中增加长期和短期用户配置文件分数

    公开(公告)号：US20070260624A1

    公开(公告)日：2007-11-08

    申请号：US11394358

    申请日：2006-03-29

    申请人： Christina Chung ,  Abhinav Gupta ,  Joshua Koran ,  Long-Ji Lin ,  Hongfeng Yin

    发明人： Christina Chung ,  Abhinav Gupta ,  Joshua Koran ,  Long-Ji Lin ,  Hongfeng Yin

    IPC分类号： G06F7/00

    CPC分类号： G06Q30/02

    摘要： A behavioral targeting system determines user profiles from online activity. The system includes a plurality of models that define parameters for determining a user profile score. Event information, which comprises on-line activity of the user, is received at an entity. To generate a user profile score, a model is selected. The model comprises recency, intensity and frequency dimension parameters. The behavioral targeting system generates a user profile score for a target objective, such as brand advertising or direct response advertising. The parameters from the model are applied to generate the user profile score in a category. The behavioral targeting system has application for use in ad serving to on-line users.

    摘要翻译： 行为定位系统从在线活动确定用户个人资料。 该系统包括多个模型，其定义用于确定用户简档分数的参数。 事件信息，包括用户的在线活动，在一个实体被接收。 要生成用户配置文件分数，选择一个模型。 该模型包括近似度，强度和频率尺寸参数。 行为定位系统为目标目标生成用户简档分数，例如品牌广告或直接回应广告。 应用来自模型的参数以在类别中生成用户简档分数。 行为定位系统具有在在线用户的广告投放中使用的应用。

    Behavioral targeting system that generates user profiles for target objectives
    10.
    发明申请
    Behavioral targeting system that generates user profiles for target objectives 有权
    为目标目标生成用户配置文件的行为定位系统

    公开(公告)号：US20070239535A1

    公开(公告)日：2007-10-11

    申请号：US11394332

    申请日：2006-03-29

    申请人： Joshua Koran ,  Christina Chung ,  Long-Ji Lin ,  Hongfeng Yin

    发明人： Joshua Koran ,  Christina Chung ,  Long-Ji Lin ,  Hongfeng Yin

    IPC分类号： G06Q30/00

    CPC分类号： G06F17/30528 ,  G06F17/30294 ,  G06F17/30587 ,  G06F17/30876 ,  G06Q30/02 ,  G06Q30/0224 ,  G06Q30/0251

    摘要： A behavioral targeting system determines user profiles from online activity. The system includes a plurality of models that define parameters for determining a user profile score. Event information, which comprises on-line activity of the user, is received at an entity. To generate a user profile score, a model is selected. The model comprises recency, intensity and frequency dimension parameters. The behavioral targeting system generates a user profile score for a target objective, such as brand advertising or direct response advertising. The parameters from the model are applied to generate the user profile score in a category. The behavioral targeting system has application for use in ad serving to on-line users.

    摘要翻译： 行为定位系统从在线活动确定用户个人资料。 该系统包括多个模型，其定义用于确定用户简档分数的参数。 事件信息，包括用户的在线活动，在一个实体被接收。 要生成用户配置文件分数，选择一个模型。 该模型包括近似度，强度和频率尺寸参数。 行为定位系统为目标目标生成用户简档分数，例如品牌广告或直接回应广告。 应用来自模型的参数以在类别中生成用户简档分数。 行为定位系统具有在在线用户的广告投放中使用的应用。