利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

23 条记录 (耗时 0.022 秒)

    Apparatus and method for gas flow management
    4.
    发明授权
    Apparatus and method for gas flow management 有权
    气流管理装置及方法

    公开(公告)号：US07397028B2

    公开(公告)日：2008-07-08

    申请号：US11216884

    申请日：2005-08-30

    申请人： Reid A. Brennen ,  Tom A van de Goor ,  Gangqiang Li ,  Kevin P. Killeen

    发明人： Reid A. Brennen ,  Tom A van de Goor ,  Gangqiang Li ,  Kevin P. Killeen

    IPC分类号： B01D59/44

    CPC分类号： H01J49/10

    摘要： The invention described herein provides a mass spectrometry system, having an ion source including an ionization device for producing ions, a collection conduit adjacent to the ionization device for collecting ions produced by the ionization device, a first gas source for supplying gas to desolvate ions produced by the ionization device, a second gas source for supplying gas at a defined flow to the ionization region, and a detector downstream from the ion source for detecting ions produced by the ion source. The invention also provides an ion source including an ionization device for producing ions, a collection conduit adjacent to the ionization device for collecting ions produced by the ionization device, a first gas source for supplying gas to desolvate ions produced by the ionization device, and a second gas source for supplying gas at a defined flow to the ionization region. A method for producing analyte ions is also disclosed. The method includes producing analyte ions from an ionization device, directing a first heated gas toward the analyte ions to desolvate the analyte ions, and directing a second gas toward the analyte ions at a defined and continual flow rate.

    摘要翻译： 本发明提供了一种质谱系统，其具有离子源，该离子源包括用于产生离子的离子化装置，与电离装置相邻的收集管，用于收集由离子化装置产生的离子;第一气体源，用于向产生的脱溶质离子供应气体 通过电离装置将用于以规定的流量供给到电离区域的气体的第二气体源和离子源下游的检测器，用于检测由离子源产生的离子。 本发明还提供了一种离子源，其包括用于产生离子的离子化装置，与离子化装置相邻的用于收集由离子化装置产生的离子的收集管，用于向离子化装置产生的脱溶质离子供给气体的第一气体源， 用于以限定的流量供应气体至电离区的第二气体源。 还公开了一种生产分析物离子的方法。 该方法包括从电离装置产生分析物离子，将第一加热气体引向分析物离子以使分析物离子脱溶质，并以限定和持续的流速将第二气体引向分析物离子。

    Electrospray devices for mass spectrometry
    5.
    发明授权
    Electrospray devices for mass spectrometry 有权
    用于质谱的电喷雾装置

    公开(公告)号：US07060975B2

    公开(公告)日：2006-06-13

    申请号：US10982189

    申请日：2004-11-05

    申请人： Karen L. Seaward ,  Hongfeng Yin ,  Kevin P. Killeen ,  Daniel Sobek ,  Daniel Roitman

    发明人： Karen L. Seaward ,  Hongfeng Yin ,  Kevin P. Killeen ,  Daniel Sobek ,  Daniel Roitman

    IPC分类号： H01J49/10

    CPC分类号： H01J49/165

    摘要： An electrospray device for a mass spectrometry system is described. The electrospray device comprises a body portion and a tip portion extending from the body portion. The tip portion comprises a polymeric material. The electrospray device also comprises a hydrophobic coating substantially selectively covering the tip portion. The hydrophobic coating is electrically nonconductive.

    摘要翻译： 描述了用于质谱系统的电喷雾装置。 电喷雾装置包括主体部分和从主体部分延伸的尖端部分。 尖端部分包括聚合材料。 电喷雾装置还包括基本上选择性地覆盖尖端部分的疏水涂层。 疏水涂层是不导电的。

    Devices and methods for separating constituents
    6.
    发明授权
    Devices and methods for separating constituents 有权
    用于分离成分的装置和方法

    公开(公告)号：US07111501B2

    公开(公告)日：2006-09-26

    申请号：US10678332

    申请日：2003-10-03

    申请人： Roy D. Rocklin ,  Kevin P. Killeen ,  Hongfeng Yin

    发明人： Roy D. Rocklin ,  Kevin P. Killeen ,  Hongfeng Yin

    IPC分类号： G01N30/00

    CPC分类号： G01N30/34 ,  G01N30/6095 ,  G01N2030/324 ,  G01N2030/347 ,  G01N2030/645

    摘要： The subject invention includes constituent separation apparatuses that include a fluid pathway and a pair of spaced-apart electrodes positioned within the pathway for detecting current flow within a mobile phase present in the pathway. Coupled to the pair of spaced-apart electrodes is a mix ratio determinator for determining the mix ratio of the mobile phase from the detected current flow. Also provided are methods that include contacting a mobile phase with an apparatus for separating constituents of a mobile phase, detecting the current flow of the mobile phase when the mobile phase is in contact with the apparatus and determining the mix ratio of the mobile phase from the detected current flow. The mix ratio may be adjusted based on the determined mix ratio. Algorithms for practicing the subject methods are also provided on computer readable mediums. Systems and kits for practicing the subject methods are also provided.

    摘要翻译： 本发明包括构成分离装置，其包括流体通道和位于通路内的一对间隔开的电极，用于检测存在于通路中的流动相中的电流。 耦合到一对间隔开的电极是用于确定流动相与检测到的电流的混合比的混合比率确定器。 还提供了包括使流动相与用于分离流动相的组分的装置接触的方法，当流动相与装置接触时检测流动相的当前流量，并确定流动相与装置的混合比 检测电流。 可以基于所确定的混合比来调节混合比。 用于实践主题方法的算法也提供在计算机可读介质上。 还提供了用于实践主题方法的系统和套件。

    System and method for using electrowetting on dielectric (EWOD) for controlling fluid in a microfluidic circuit
    9.
    发明申请
    System and method for using electrowetting on dielectric (EWOD) for controlling fluid in a microfluidic circuit 审中-公开
    在电介质（EWOD）上使用电润湿来控制微流体电路中的流体的系统和方法

    公开(公告)号：US20080264506A1

    公开(公告)日：2008-10-30

    申请号：US11796891

    申请日：2007-04-30

    申请人： Timothy Beerling ,  Kevin P. Killeen

    发明人： Timothy Beerling ,  Kevin P. Killeen

    IPC分类号： F15C1/04 ,  G01N27/26

    CPC分类号： B01L3/502792 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2400/0427 ,  Y10T137/2191 ,  Y10T137/2213

    摘要： A system for controlling fluid flow in a microfluidic circuit includes at least one microfluidic channel having a first fluid, a switch element coupled to the microfluidic channel, the switch element comprising at least one inlet, at least one outlet and a second fluid, the second fluid being immiscible with respect to the first fluid. The system also includes an actuator configured to alter the position of the second fluid, such that when in a first position, the second fluid allows the first fluid to flow from the at least one inlet to the at least one outlet, and such that when in a second position, the second fluid prevents the first fluid from flowing from the at least one inlet to the at least one outlet.

    摘要翻译： 用于控制微流体回路中的流体流动的系统包括至少一个具有第一流体的微流体通道，耦合到微流体通道的开关元件，该开关元件包括至少一个入口，至少一个出口和第二流体，第二流体 流体相对于第一流体是不混溶的。 该系统还包括被配置为改变第二流体的位置的致动器，使得当处于第一位置时，第二流体允许第一流体从至少一个入口流动到至少一个出口，并且使得当 在第二位置，第二流体防止第一流体从至少一个入口流到至少一个出口。