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    Flexible Circuit Electrode Array
    4.
    发明申请
    Flexible Circuit Electrode Array 有权
    柔性电路电极阵列

    公开(公告)号：US20090264972A1

    公开(公告)日：2009-10-22

    申请号：US12163658

    申请日：2008-06-27

    申请人： David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Boon-Khai Ng ,  James Singleton Little

    发明人： David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Boon-Khai Ng ,  James Singleton Little

    IPC分类号： A61N1/05 ,  B29C70/88 ,  B05D5/12

    CPC分类号： A61N1/0543 ,  A61N1/0541 ,  H05K1/036 ,  H05K1/0393 ,  H05K1/118 ,  H05K3/28 ,  H05K2201/0133 ,  H05K2201/0195 ,  Y10T156/1002

    摘要： A flexible circuit electrode array, which comprises: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a partial or entire coating of the base and top layer by a soft polymer.A method of preparing a flexible circuit electrode array, comprising: (a) providing a first soft polymer layer; (b) depositing a first a base layer on the first soft polymer layer; (c) providing a metal thin film on the base layer; (d) depositing a top polymer layer on the metal thin film; (e) providing holes in the top polymer layer; (f) depositing a second soft polymer layer on the top polymer layer; (g) providing holes in the second soft polymer layer for bond pads and electrodes; and (h) preparing electrodes in the provided holes.A method of preparing a flexible circuit electrode array, comprising: (a) providing a first soft polymer layer; (b) depositing a first a base layer on the first soft polymer layer; (c) providing a metal thin film on the base layer; (d) depositing a top polymer layer on the metal thin film; (e) depositing a second soft polymer layer on the top polymer layer; (f) providing holes in the second soft polymer layer and in the top polymer layer for bond pads and electrodes; and (g) preparing electrodes in the provided holes.

    摘要翻译： 一种柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层; 以及通过软聚合物的基底和顶层的部分或全部涂层。 一种制备柔性电路电极阵列的方法，包括：（a）提供第一软聚合物层; （b）在第一软聚合物层上沉积第一基底层; （c）在基层上提供金属薄膜; （d）在金属薄膜上沉积顶部聚合物层; （e）在顶部聚合物层中提供孔; （f）在顶部聚合物层上沉积第二软聚合物层; （g）在第二软聚合物层中为接合焊盘和电极提供孔; 和（h）在所提供的孔中制备电极。 一种制备柔性电路电极阵列的方法，包括：（a）提供第一软聚合物层; （b）在第一软聚合物层上沉积第一基底层; （c）在基层上提供金属薄膜; （d）在金属薄膜上沉积顶部聚合物层; （e）在顶部聚合物层上沉积第二软聚合物层; （f）在第二软聚合物层和顶部聚合物层中提供用于接合焊盘和电极的孔; 和（g）在所提供的孔中制备电极。

    Cochlear Stimulation Device
    5.
    发明申请
    Cochlear Stimulation Device 有权
    耳蜗刺激装置

    公开(公告)号：US20090143848A1

    公开(公告)日：2009-06-04

    申请号：US12267489

    申请日：2008-11-07

    申请人： Robert J. Greenberg ,  David Daomin Zhou ,  Jordan Matthew Neysmith ,  Kelly H. McClure ,  Jianing Wei ,  Neil Hamilton Talbot ,  James Singleton Little

    发明人： Robert J. Greenberg ,  David Daomin Zhou ,  Jordan Matthew Neysmith ,  Kelly H. McClure ,  Jianing Wei ,  Neil Hamilton Talbot ,  James Singleton Little

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0541 ,  A61N1/0472

    摘要： A cochlear stimulation device comprising an electrode array designed to provide enhanced charge injection capacity necessary for neural stimulation. The electrode array comprises electrodes with high surface area or a fractal geometry and correspondingly high electrode capacitance and low electrical impedance. The resultant electrodes have a robust surface and sufficient mechanical strength to withstand physical stress vital for long term stability. The device further comprises wire traces having a multilayer structure which provides a reduced width for the conducting part of the electrode array. The cochlear prosthesis is attached by a grommet to the cochleostomy that is made from a single piece of biocompatible polymer. The device, designed to achieve optimum neural stimulation by appropriate electrode design, is a significant improvement over commercially available hand-built devices.

    摘要翻译： 耳蜗刺激装置包括设计成提供神经刺激所需的增强的电荷注入能力的电极阵列。 电极阵列包括具有高表面积或分形几何形状的电极以及相当高的电极电容和低的电阻抗。 所得电极具有坚固的表面和足够的机械强度以抵抗对于长期稳定性至关重要的物理应力。 该装置还包括具有多层结构的导线迹线，其为电极阵列的导电部分提供减小的宽度。 耳蜗假体通过索环连接到由单一生物相容性聚合物制成的耳蜗切开术。 该设备旨在通过适当的电极设计实现最佳神经刺激，这是相对于市售的手工设备的显着改进。

    Cochlear stimulation device
    6.
    发明授权
    Cochlear stimulation device 有权
    人工耳蜗刺激装置

    公开(公告)号：US08874239B2

    公开(公告)日：2014-10-28

    申请号：US12267489

    申请日：2008-11-07

    申请人： Robert J. Greenberg ,  David Daomin Zhou ,  Jordan Matthew Neysmith ,  Kelly H. McClure ,  Jianing Wei ,  Neil Hamilton Talbot ,  James Singleton Little

    发明人： Robert J. Greenberg ,  David Daomin Zhou ,  Jordan Matthew Neysmith ,  Kelly H. McClure ,  Jianing Wei ,  Neil Hamilton Talbot ,  James Singleton Little

    IPC分类号： A61N1/00 ,  A61N1/05

    CPC分类号： A61N1/0541 ,  A61N1/0472

    摘要： A cochlear stimulation device comprising an electrode array designed to provide enhanced charge injection capacity necessary for neural stimulation. The electrode array comprises electrodes with high surface area or a fractal geometry and correspondingly high electrode capacitance and low electrical impedance. The resultant electrodes have a robust surface and sufficient mechanical strength to withstand physical stress vital for long term stability. The device further comprises wire traces having a multilayer structure which provides a reduced width for the conducting part of the electrode array. The cochlear prosthesis is attached by a grommet to the cochleostomy that is made from a single piece of biocompatible polymer. The device, designed to achieve optimum neural stimulation by appropriate electrode design, is a significant improvement over commercially available hand-built devices.

    摘要翻译： 耳蜗刺激装置包括设计成提供神经刺激所需的增强的电荷注入能力的电极阵列。 电极阵列包括具有高表面积或分形几何形状的电极以及相当高的电极电容和低的电阻抗。 所得电极具有坚固的表面和足够的机械强度以抵抗对于长期稳定性至关重要的物理应力。 该装置还包括具有多层结构的导线迹线，其为电极阵列的导电部分提供减小的宽度。 耳蜗假体通过索环连接到由单一生物相容性聚合物制成的耳蜗切开术。 该设备旨在通过适当的电极设计实现最佳神经刺激，这是相对于市售的手工设备的显着改进。

    Return Electrode for a Flexible Circuit Electrode Array
    7.
    发明申请
    Return Electrode for a Flexible Circuit Electrode Array 审中-公开
    用于柔性电路电极阵列的返回电极

    公开(公告)号：US20090118805A1

    公开(公告)日：2009-05-07

    申请号：US12168740

    申请日：2008-07-07

    申请人： Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Kelly H. McClure ,  Brian V. Mech ,  Rongqing Dai ,  David Daomin Zhou ,  Gaillard R. Nolan

    发明人： Robert J. Greenberg ,  Jordan Matthew Neysmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Kelly H. McClure ,  Brian V. Mech ,  Rongqing Dai ,  David Daomin Zhou ,  Gaillard R. Nolan

    IPC分类号： A61F9/08 ,  A61N1/05

    CPC分类号： A61N1/0543 ,  A61N1/36046 ,  H05K1/118

    摘要： In a visual prosthesis electrodes stimulate retinal tissue to induce the perception of light to a user implanted with the prosthesis. The prosthesis must have a return, or common, electrode to make a complete circuit with the retinal tissue. To avoid stimulating tissue with the return electrode, it is advantageous if the electrode is large.The invention involver a flexible circuit electrode array comprising a polymer base layer, metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue a polymer top layer deposited on said polymer base layer and said metal traces, and a return electrode separate from said stimulating electrodes.The flexible circuit electrode array comprises a secondary coil for receiving visual data; an electronics package electrically coupled to said receiving coil, and a plurality of stimulating electrode electrically coupled to said electronics package.

    摘要翻译： 在视觉假体中，电极刺激视网膜组织以诱导植入假体的使用者对光的感知。 假体必须具有返回或常见的电极以与视网膜组织形成完整的电路。 为了避免用返回电极刺激组织，如果电极很大，则是有利的。 本发明涉及柔性电路电极阵列，其包括聚合物基底层，沉积在所述聚合物基底层上的金属迹线，包括适于刺激沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层的神经组织的电极和分离的回流电极 从所述刺激电极。 柔性电路电极阵列包括用于接收视觉数据的次级线圈; 电耦合到所述接收线圈的电子封装，以及电耦合到所述电子封装的多个刺激电极。