公开(公告)号：US20070275394A1

公开(公告)日：2007-11-29

申请号：US11634437

申请日：2006-12-06

申请人： Dong Shin ,  Moon Jung ,  Se Park ,  Hyeon Pyo ,  Chang Choi

发明人： Dong Shin ,  Moon Jung ,  Se Park ,  Hyeon Pyo ,  Chang Choi

IPC分类号： C12Q1/68 ,  C12M3/00

CPC分类号： C12Q1/6825 ,  B82B1/001 ,  C12Q2565/133 ,  C12Q2563/137

摘要： Provided are a nucleic acid nanostructure including: a substrate; a nucleic acid quadruplex immobilized on the substrate to be vertical with respect to the substrate; a metal ion present in a unit lattice of the nucleic acid quadruplex, the unit lattice being made up of eight nucleobases; and a nanoparticle bound to an end of the nucleic acid quadruplex, and a method of manufacturing the same. According to the method, a nucleic acid nanostructure having an array of nanoparticles can be manufactured. The nucleic acid nanostructure can be applied as a sensor nanostructure for sensors such as gas sensors, chemical sensors, and biosensors. In particular, a nucleic acid nanostructure in which metal nanoparticles, e.g., gold or silver, are introduced can be useful as a device having local surface plasmon characteristics.

摘要翻译： 提供的核酸纳米结构包括：底物; 固定在所述基板上的相对于所述基板垂直的核酸四重链; 存在于核酸四联体的单位晶格中的金属离子，单位晶格由八个核碱基组成; 和结合到核酸四链体末端的纳米颗粒及其制造方法。 根据该方法，可以制造具有纳米颗粒阵列的核酸纳米结构。 核酸纳米结构可用作传感器的传感器纳米结构，如气体传感器，化学传感器和生物传感器。 特别地，其中引入金属纳米颗粒例如金或银的核酸纳米结构可用作具有局部表面等离子体特征的器件。

公开(公告)号：US20060030030A1

公开(公告)日：2006-02-09

申请号：US11100544

申请日：2005-04-07

申请人： Moon Jung ,  Dong Shin ,  Young Kim ,  Se Park ,  Hyeon Pyo ,  Chang Choi

发明人： Moon Jung ,  Dong Shin ,  Young Kim ,  Se Park ,  Hyeon Pyo ,  Chang Choi

IPC分类号： C12M1/34 ,  G02F1/13

CPC分类号： G03F7/70291 ,  G02F1/1393 ,  G03F7/70566

摘要： The present invention relates to a programmable mask used in a photolithography process for fabricating a biomolecule array and a method of fabricating a biomolecule array using the same and, more particularly, to a programmable mask which can increase a contrast ratio of transmittance versus shielding of light incident to a liquid crystal which constitutes each pixel by irradiating parallel ultraviolet (“UV”) light generated from an external parallel light exposure device to a certain cell and using a vertically aligned liquid crystal panel or an LC panel having no spacer, and a method of fabricating a biomolecule array using the same.

摘要翻译： 本发明涉及用于制造生物分子阵列的光刻工艺中使用的可编程掩模，以及使用该可编程掩模制造生物分子阵列的方法，更具体地说，涉及一种可增加透射率对光屏蔽对比度的可编程掩模 通过将从外部平行曝光装置产生的平行紫外线（“UV”）光照射到某个单元并使用垂直取向的液晶面板或不具有间隔物的LC面板，对构成每个像素的液晶进行入射;以及方法 制造使用其的生物分子阵列。

公开(公告)号：US20070131552A1

公开(公告)日：2007-06-14

申请号：US11634710

申请日：2006-12-06

申请人： Moon Jung ,  Se Park ,  Dong Shin ,  Hyeon Pyo

发明人： Moon Jung ,  Se Park ,  Dong Shin ,  Hyeon Pyo

IPC分类号： C07K1/26 ,  G01N27/00

CPC分类号： G01N27/44704 ,  A61B5/0002 ,  G01N33/5438 ,  G01N33/544 ,  G01N33/548

摘要： Provided are a biomolecule detection device, a mobile phone for biomolecule detection, and a biomolecule detection method. The biomolecule detection device includes an electrophoresis unit comprising an electrophoretic gel filtering erythrocytes and leukocytes in blood and transferring proteins and DNAs in the blood, and at least one type of a probe biomolecule, immobilized in the electrophoretic gel, reacting with a target biomolecule; a conversion unit converting a result of a reaction between the target biomolecule and the probe biomolecule to an electrical signal; and a lead-out unit receiving, converting, and transmitting the electrical signal.

摘要翻译： 提供了生物分子检测装置，用于生物分子检测的移动电话和生物分子检测方法。 生物分子检测装置包括电泳单元，其包含在血液中过滤红细胞和白细胞并在血液中转移蛋白质和DNA的电泳凝胶，以及固定在电泳凝胶中的至少一种类型的探针生物分子，与目标生物分子反应; 转换单元，将目标生物分子与探针生物分子之间的反应结果转换为电信号; 以及接收，转换和发送电信号的引出单元。

公开(公告)号：US20070134831A1

公开(公告)日：2007-06-14

申请号：US11634408

申请日：2006-12-06

申请人： Moon Jung ,  Dong Shin ,  Se Park ,  Hyeon Pyo ,  Chi Jun

发明人： Moon Jung ,  Dong Shin ,  Se Park ,  Hyeon Pyo ,  Chi Jun

IPC分类号： H01L21/00

CPC分类号： G03F7/70291 ,  B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00434 ,  B01J2219/00448 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00689 ,  B01J2219/00711 ,  B01J2219/0072 ,  B01J2219/00722 ,  B82Y30/00 ,  G03F7/70275

摘要： Provided are a programmable mask for promptly fabricating a biomolecule or polymer array having high density, an apparatus for fabricating a biomolecule or polymer array including the mask, and a method of fabricating a biomolecule or polymer array using the programmable mask. The programmable mask for fabricating a biomolecule array or polymer array includes a first substrate including a black matrix having openings and first pixel electrodes; a second substrate including thin film transistors for switching pixel regions which correspond to the openings according to applied electric signals and second pixel electrodes connected to drain electrodes of the thin film transistors; a liquid crystal layer interposed between the first substrate and the second substrate, the liquid crystal layer including liquid crystal whose arrangement can be changed according to electric signals of the thin film transistors so as to selectively transmit light; a first polarizing plate laminated on one side of the first substrate; a second polarizing plate laminated on one side of the second substrate; and a lens array layer laminated on one side of the second polarizing plate including lenses which correspond to the pixel regions.

摘要翻译： 提供了一种用于及时制造具有高密度的生物分子或聚合物阵列的可编程掩模，用于制造包括掩模的生物分子或聚合物阵列的装置，以及使用可编程掩模制造生物分子或聚合物阵列的方法。 用于制造生物分子阵列或聚合物阵列的可编程掩模包括包括具有开口的黑矩阵的第一基底和第一像素电极; 第二基板，包括用于根据施加的电信号切换对应于开口的像素区域的薄膜晶体管和连接到薄膜晶体管的漏极的第二像素电极; 介于所述第一基板和所述第二基板之间的液晶层，所述液晶层包括可根据所述薄膜晶体管的电信号而配置的液晶，以选择性地透射光; 层叠在第一基板的一侧的第一偏振片; 层叠在所述第二基板的一侧的第二偏振片; 以及层叠在第二偏振片的一侧上的透镜阵列层，其包括对应于像素区域的透镜。

公开(公告)号：US20050142872A1

公开(公告)日：2005-06-30

申请号：US11026572

申请日：2004-12-30

申请人： Se Park

发明人： Se Park

IPC分类号： H01L21/027 ,  H01L21/44 ,  H01L21/768

CPC分类号： H01L21/76802

摘要： An object of the present invention is to provide a method that is capable of forming easily a fine pattern corresponding to a high integration density device, without using a new exposure apparatus. The object of the present invention as noted above is accomplished by etching a second insulating layer to expose a portion of an underlying first insulating layer; forming a third insulating layer on the entire surface of the substrate; etching the third insulating layer and the first insulating layer using the second insulating layer as an etch barrier, to define a pattern region; forming a material layer on the entire surface of the substrate so as to fill the pattern region; and planarizing the material layer and/or substrate so as to expose the first insulating layer, to form a pattern.

摘要翻译： 本发明的目的是提供一种能够容易地形成与高集成度密度装置相对应的精细图案的方法，而不使用新的曝光装置。 如上所述的本发明的目的是通过蚀刻第二绝缘层以暴露下面的第一绝缘层的一部分来实现; 在所述基板的整个表面上形成第三绝缘层; 使用第二绝缘层作为蚀刻阻挡层蚀刻第三绝缘层和第一绝缘层，以限定图案区域; 在基板的整个表面上形成材料层以填充图案区域; 并且平坦化材料层和/或衬底以露出第一绝缘层，以形成图案。

公开(公告)号：US20060196230A1

公开(公告)日：2006-09-07

申请号：US11244664

申请日：2005-10-06

申请人： Se Park ,  Jin-Haing Kim ,  Jin-Han Kim ,  Mun-Hyun Do

发明人： Se Park ,  Jin-Haing Kim ,  Jin-Han Kim ,  Mun-Hyun Do

IPC分类号： C03B37/018

CPC分类号： H01J37/32541 ,  C03B37/01426 ,  H05H1/46

摘要： A plasma apparatus is disclosed. The plasma apparatus includes an internal electrode having a hollow section for receiving precursor gas and oxygen gas therein, an external electrode accommodating the internal electrode therein while forming a gap therebetween in such a manner that inert gas and oxygen gas are introduced into the gap. The plasma apparatus also includes a power source for applying a DC voltage or a radio frequency (RF) AC voltage to the internal and external electrodes in order to generate plasma between the internal and external electrodes.

摘要翻译： 公开了一种等离子体装置。 等离子体装置包括内部电极，其具有用于接收前体气体和氧气的中空部分，外部电极容纳内部电极，同时在惰性气体和氧气引入到间隙中形成间隙。 等离子体装置还包括用于向内部和外部电极施加直流电压或射频（RF）AC电压以在内部和外部电极之间产生等离子体的电源。

公开(公告)号：US20060014937A1

公开(公告)日：2006-01-19

申请号：US11100553

申请日：2005-04-07

申请人： Heui Kang ,  Byung Lee ,  Se Park ,  Moo Song ,  Tae Yoo ,  Jae Lee ,  Chang Kim ,  Sang Park ,  Kang Na

发明人： Heui Kang ,  Byung Lee ,  Se Park ,  Moo Song ,  Tae Yoo ,  Jae Lee ,  Chang Kim ,  Sang Park ,  Kang Na

IPC分类号： A61K39/42 ,  C07K16/44

CPC分类号： C07K16/082 ,  C07K2317/24

摘要： A humanized antibody of the present invention shows similar antigen-binding affinity to a mouse monoclonal antibody and significantly low immunogenecity. Therefore, the humanized antibody of the present invention can be effectively used for treating chronic hepatitis B and preventing HBV infection of a patient received liver transplantation and vertical transmission from a mother infected with HBV to a fetus.

摘要翻译： 本发明的人源化抗体对小鼠单克隆抗体显示出类似的抗原结合亲和力，并且显着低的免疫原性。 因此，本发明的人源化抗体可以有效地用于治疗慢性乙型肝炎并预防接受肝移植的患者和从感染HBV的母亲到胎儿的垂直传播的HBV感染。

公开(公告)号：US20050139993A1

公开(公告)日：2005-06-30

申请号：US10899177

申请日：2004-07-27

申请人： Dae Lee ,  Hae Yang ,  Yong Lim ,  Kwang Chung ,  Sung Kim ,  Se Park ,  Kyu Kim ,  Yun Kim

发明人： Dae Lee ,  Hae Yang ,  Yong Lim ,  Kwang Chung ,  Sung Kim ,  Se Park ,  Kyu Kim ,  Yun Kim

IPC分类号： H01L23/02 ,  B01J19/00 ,  B01L3/00 ,  C40B60/14 ,  H01L23/10 ,  H01L27/14 ,  H01L29/06 ,  H01L29/82 ,  H01L29/84

CPC分类号： B01J19/0093 ,  B01J2219/00495 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00783 ,  B01J2219/00804 ,  B01J2219/00833 ,  B01J2219/00853 ,  B01J2219/00858 ,  B01J2219/00873 ,  B01J2219/00961 ,  B01L3/502707 ,  B01L3/50851 ,  B01L2200/12 ,  B01L2200/147 ,  B01L2300/0819 ,  B01L2300/12 ,  B01L2300/1827 ,  B33Y80/00 ,  C40B60/14 ,  G01N27/128

摘要： Provided are a plastic microfabricated structure, and a microfabricated thermal device, a microfabricated reactor, a microfabricated reactor array and a micro array using the same, which may be applied to a bio chip, and the present invention may fabricate the plastic microfabricated structure for providing a heating region by means of insulating plastic, which has a thin thickness, flatness enough to allow a photolithography process to be performed, thermal isolation in its some or total area, and a small thermal mass, and on top of the heating region of the plastic microfabricated structure, a heater, a temperature sensor for sensing a temperature, an electrode, and an electrode pad are formed to thereby fabricate the microfabricated heating device, whereby element may be readily fabricated at a low cost, and the heating region is formed of a plastic thin layer, so that uniform temperature control is possible even with a low power, and various samples may be thermally treated at a fast speed to obtain their reaction and analysis.

摘要翻译： 本发明提供一种塑料微制造结构，微制造热装置，微制造反应器，微制造反应器阵列和使用其的微阵列，其可以应用于生物芯片，并且本发明可以制造塑料微制造结构以提供 通过绝缘塑料的加热区域，其具有薄的厚度，足够的平坦度，以允许执行光刻工艺，其一些或总面积的热隔离和小的热质量，以及在 形成塑料微加工结构，加热器，用于感测温度的温度传感器，电极和电极焊盘，从而制造微制造加热装置，从而可以以低成本容易地制造元件，并且加热区域由 塑料薄层，使得即使在低功率下也能进行均匀的温度控制，并且各种样品可以在fa处进行热处理 速度获得反应和分析。

公开(公告)号：US20060185398A1

公开(公告)日：2006-08-24

申请号：US11348390

申请日：2006-02-06

申请人： Jin-Haing Kim ,  Se Park ,  Mun-Hyun Do

发明人： Jin-Haing Kim ,  Se Park ,  Mun-Hyun Do

IPC分类号： C03B37/07 ,  C03B37/018

CPC分类号： C03B37/01807 ,  C03B2201/31 ,  C03B2203/26 ,  C03B2207/70

摘要： A method for fabricating a multimode optical fiber preform having a longitudinal uniformity is provided. The method of fabricating includes performing a plurality of radial deposition passes using a thermal source while inserting raw materials into a glass tube. A reference chemical core shape index is set to determine a refractive index profile of a preform section. A core shape index distribution of each longitudinal deposition pass varying in a longitudinal direction of the glass tube is set such that an error of a reference chemical core shape index distribution in the longitudinal direction of the preform defined by the reference chemical core shape index is compensated for and such that a uniform chemical core shape index is obtained in the longitudinal direction. Deposition is performed while an amount of raw materials corresponding to a preset chemical core shape index is inserted in each longitudinal deposition pass of each radial deposition pass.

摘要翻译： 提供了一种制造具有纵向均匀性的多模光纤预制件的方法。 制造方法包括在将原材料插入玻璃管中时使用热源进行多个径向沉积通道。 设定参考化学品核心形状指数以确定预制件部分的折射率分布。 设定在玻璃管的长度方向上变化的各纵向沉积通路的芯形指数分布，使得由参考化学核心形状指数所限定的预成型件在长度方向上的基准化学品核心形状指数分布的误差被补偿 并且使得在纵向方向上获得均匀的化学核心形状指数。 在每个径向沉积通道的每个纵向沉积通道中插入对应于预设化学核心形状指数的原料的量的沉积。

公开(公告)号：US20060077716A1

公开(公告)日：2006-04-13

申请号：US11158346

申请日：2005-06-22

申请人： Se Park

发明人： Se Park

IPC分类号： G11C11/34

CPC分类号： G11C8/08 ,  G11C16/0483 ,  G11C16/08 ,  G11C16/12

摘要： A row decoder circuit of a NAND flash memory and method of supplying an operating voltage using the same. To prevent an operating voltage (e.g., a program voltage, a pass voltage, or a read voltage) from being abnormally transferred to a gate of a memory cell because a pumping voltage is applied to a gate of a high-voltage pass transistor of the row decoder circuit in a level lower than a target voltage, the pumping voltage is first applied to the gate of the high-voltage pass transistor (i.e., precharging the gate of the high-voltage pass transistor) and next the operating voltage is applied to a drain of the high voltage pass transistor. Thus, the pumping voltage becomes higher than the target voltage due to a self-boosting effect through the structure of transistor, enabling the operating voltage to be normally transferred to the gate of the memory cell.

摘要翻译： NAND闪速存储器的行解码器电路和使用其的工作电压的提供方法。 为了防止工作电压（例如，编程电压，通过电压或读取电压）异常地传送到存储器单元的栅极，因为泵浦电压被施加到高压通过晶体管的栅极 行解码器电路的电平低于目标电压，首先将泵浦电压施加到高压通过晶体管的栅极（即，对高压通过晶体管的栅极进行预充电），接下来将工作电压施加到 高压晶体管的漏极。 因此，由于通过晶体管的结构的自增强效应，泵浦电压变得高于目标电压，使得工作电压能够正常地传送到存储器单元的栅极。