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公开(公告)号:US08328023B2
公开(公告)日:2012-12-11
申请号:US12620754
申请日:2009-11-18
申请人: Douglas E. Weiss , Clinton P. Waller, Jr. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
发明人: Douglas E. Weiss , Clinton P. Waller, Jr. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
CPC分类号: B01D39/163 , C08F255/00 , C08F289/00 , C08F291/00 , C08L51/08 , C08L2666/02
摘要: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.
摘要翻译: 公开了接枝非织造基材,其平均纤维尺寸为0.7-15微米,空隙体积为50至95%,以及包含接枝到非织造基材表面的阳离子氨基烷基(甲基)丙烯酰基单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物纯化或分离靶物质,例如寡核苷酸或单克隆抗体(MAb)。
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公开(公告)号:US20100155323A1
公开(公告)日:2010-06-24
申请号:US12620754
申请日:2009-11-18
申请人: Douglas E. Weiss , Clinton P. Waller, JR. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
发明人: Douglas E. Weiss , Clinton P. Waller, JR. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
CPC分类号: B01D39/163 , C08F255/00 , C08F289/00 , C08F291/00 , C08L51/08 , C08L2666/02
摘要: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.
摘要翻译: 公开了接枝非织造基材,其平均纤维尺寸为0.7-15微米,空隙体积为50至95%,以及包含接枝到非织造基材表面的阳离子氨基烷基(甲基)丙烯酰基单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物纯化或分离靶物质,例如寡核苷酸或单克隆抗体(MAb)。
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公开(公告)号:US20100320138A1
公开(公告)日:2010-12-23
申请号:US12819261
申请日:2010-06-21
CPC分类号: B01D67/0093 , B01D39/1623 , B01D39/1692 , B01D63/00 , B01D63/10 , B01D63/14 , B01D67/009 , B01D69/10 , B01D69/105 , B01D2239/0421 , B01D2239/0464 , B01D2239/065 , B01D2239/069 , B01D2239/10 , B01D2239/1216 , B01D2239/1225 , B01D2239/1266 , B01D2239/1291 , B01D2323/385 , D04H1/42 , D04H1/4334 , D04H1/4382 , D04H1/56 , D06M14/26 , D06M14/28 , Y10T442/2008
摘要: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.
摘要翻译: 公开了接枝非织造基材,其平均纤维尺寸为0.7至15微米,空隙体积为50至95%,以及包含接枝到非织造基材表面的阴离子单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物中纯化或分离靶物质,例如单克隆抗体(MAb)。
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公开(公告)号:US08652582B2
公开(公告)日:2014-02-18
申请号:US12937458
申请日:2009-05-26
申请人: Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, Jr. , Douglas E. Weiss
发明人: Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, Jr. , Douglas E. Weiss
IPC分类号: C08F2/46
CPC分类号: C07C279/12 , B01D39/1676 , B01J20/285 , C07C277/08 , C07C279/14 , C07C281/16 , C07K1/34 , C08F259/08 , C08F283/04 , C08G69/48 , C08J7/18 , C08J9/283 , C08J9/42 , C08J2327/16 , C08J2377/00 , C12N7/00 , Y02C10/08 , Y10T428/31855
摘要: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed. The ligand functionalized substrate may be described as the grafted reaction product of a substrate and a ligand monomer of Formula I:
摘要翻译: 配体功能化底物,制备配体官能化底物的方法,以及使用官能化底物的方法。 配体官能化底物可以描述为底物和式I的配体单体的接枝反应产物:
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公开(公告)号:US08329034B2
公开(公告)日:2012-12-11
申请号:US12819261
申请日:2010-06-21
CPC分类号: B01D67/0093 , B01D39/1623 , B01D39/1692 , B01D63/00 , B01D63/10 , B01D63/14 , B01D67/009 , B01D69/10 , B01D69/105 , B01D2239/0421 , B01D2239/0464 , B01D2239/065 , B01D2239/069 , B01D2239/10 , B01D2239/1216 , B01D2239/1225 , B01D2239/1266 , B01D2239/1291 , B01D2323/385 , D04H1/42 , D04H1/4334 , D04H1/4382 , D04H1/56 , D06M14/26 , D06M14/28 , Y10T442/2008
摘要: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising anionic monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as monoclonal antibodies (MAb), from a fluid mixture.
摘要翻译: 公开了接枝非织造基材,其平均纤维尺寸为0.7至15微米,空隙体积为50至95%,以及包含接枝到非织造基材表面的阴离子单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物中纯化或分离靶物质,例如单克隆抗体(MAb)。
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公开(公告)号:US20110033633A1
公开(公告)日:2011-02-10
申请号:US12937458
申请日:2009-05-26
申请人: Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, JR. , Douglas E. Weiss
发明人: Catherine A. Bothof , Yi He , Jerald K. Rasmussen , Kannan Seshadri , Clinton P. Waller, JR. , Douglas E. Weiss
IPC分类号: C08F2/54 , C07C233/09 , C07C229/26 , C07C69/54 , C08F2/48
CPC分类号: C07C279/12 , B01D39/1676 , B01J20/285 , C07C277/08 , C07C279/14 , C07C281/16 , C07K1/34 , C08F259/08 , C08F283/04 , C08G69/48 , C08J7/18 , C08J9/283 , C08J9/42 , C08J2327/16 , C08J2377/00 , C12N7/00 , Y02C10/08 , Y10T428/31855
摘要: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
摘要翻译: 配体功能化底物,制备配体官能化底物的方法,以及使用官能化底物的方法。
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公开(公告)号:US09056316B2
公开(公告)日:2015-06-16
申请号:US13703267
申请日:2011-06-17
申请人: Del R. Lawson , James I. Hembre , Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , Robert T. Fitzsimons, Jr. , Andrew W. Rabins , Taib K. Ansera
发明人: Del R. Lawson , James I. Hembre , Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , Robert T. Fitzsimons, Jr. , Andrew W. Rabins , Taib K. Ansera
IPC分类号: B01J41/14 , B01J39/20 , C08J3/24 , C08L33/26 , C08L101/00
CPC分类号: B01J41/14 , B01J39/20 , B01J39/26 , B01J41/20 , C08J3/246 , C08J2333/26 , C08J2400/00 , C08L23/06 , C08L33/26 , C08L77/00 , C08L101/00 , C08L2205/04 , C08L2205/16 , C08L2205/22 , C08L2312/00
摘要: Semi-interpenetrating polymeric networks are described. More specifically, the semi-interpenetrating polymeric networks include at least two polymers that are closely associated. The first polymer is an ionic polymer that is not crosslinked. The second polymer is a cross-linked polymer that can be either another ionic polymer or a non-ionic polymer. Methods of making the semi-interpenetrating polymeric networks, articles containing the semi-interpenetrating polymeric networks, and methods of using the semi-interpenetrating polymeric networks are also described. The semi-interpenetrating polymeric networks can function as ion exchange resins.
摘要翻译: 描述了半互穿聚合物网络。 更具体地说,半互穿聚合物网络包括至少两种紧密相关的聚合物。 第一聚合物是不交联的离子聚合物。 第二聚合物是可以是另一离子聚合物或非离子聚合物的交联聚合物。 还描述了制备半互穿聚合物网络的方法,含有半互穿聚合物网络的制品以及使用半互穿聚合物网络的方法。 半互穿聚合物网络可用作离子交换树脂。
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公开(公告)号:US20130090397A1
公开(公告)日:2013-04-11
申请号:US13703267
申请日:2011-06-17
申请人: Del R. Lawson , James I. Hembre , Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , Robert T. Fitzsimons, JR. , Andrew W. Rabins , Taib K. Ansera
发明人: Del R. Lawson , James I. Hembre , Jerald K. Rasmussen , Catherine A. Bothof , Kannan Seshadri , Robert T. Fitzsimons, JR. , Andrew W. Rabins , Taib K. Ansera
CPC分类号: B01J41/14 , B01J39/20 , B01J39/26 , B01J41/20 , C08J3/246 , C08J2333/26 , C08J2400/00 , C08L23/06 , C08L33/26 , C08L77/00 , C08L101/00 , C08L2205/04 , C08L2205/16 , C08L2205/22 , C08L2312/00
摘要: Semi-interpenetrating polymeric networks are described. More specifically, the semi-interpenetrating polymeric networks include at least two polymers that are closely associated. The first polymer is an ionic polymer that is not crosslinked. The second polymer is a cross-linked polymer that can be either another ionic polymer or a non-ionic polymer. Methods of making the semi-interpenetrating polymeric networks, articles containing the semi-interpenetrating polymeric networks, and methods of using the semi-interpenetrating polymeric networks are also described. The semi-interpenetrating polymeric networks can function as ion exchange resins.
摘要翻译: 描述了半互穿聚合物网络。 更具体地说,半互穿聚合物网络包括至少两种紧密相关的聚合物。 第一聚合物是不交联的离子聚合物。 第二聚合物是可以是另一离子聚合物或非离子聚合物的交联聚合物。 还描述了制备半互穿聚合物网络的方法,含有半互穿聚合物网络的制品以及使用半互穿聚合物网络的方法。 半互穿聚合物网络可用作离子交换树脂。
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公开(公告)号:US20110006007A1
公开(公告)日:2011-01-13
申请号:US12746961
申请日:2008-12-19
申请人: Gokhan Kuruc , Marjorie Bucholz , Todd E. Arnold , Robert T. Fitzsimons, JR. , Kannan Seshadri , Steven M. Heilmann , Andrew W. Rabins , Catherine A. Bothof
发明人: Gokhan Kuruc , Marjorie Bucholz , Todd E. Arnold , Robert T. Fitzsimons, JR. , Kannan Seshadri , Steven M. Heilmann , Andrew W. Rabins , Catherine A. Bothof
CPC分类号: B01J20/26 , B01D39/1653 , B01D2239/086 , B01J20/2803 , B01J20/285 , B01J2220/58 , B01J2220/66 , C02F1/285 , C02F2103/343
摘要: Provided are filtration media, matrixes, and systems for liquid purification that utilize functional polymer particles. The functional polymer particles can comprise a cationic charge. Exemplary functional polymer particles comprise comprise [3-(methacryloylamino)propyl]-trimethylammonium chloride (MAPTAC) polymerized with trimethylolpropane trimethacrylate (TMPTMA).
摘要翻译: 提供了使用功能性聚合物颗粒的过滤介质,基质和用于液体纯化的系统。 功能性聚合物颗粒可以包含阳离子电荷。 示例性功能性聚合物颗粒包含由三羟甲基丙烷三甲基丙烯酸酯(TMPTMA)聚合的[3-(甲基丙烯酰氨基)丙基] - 三甲基氯化铵(MAPTAC)。
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公开(公告)号:US20110217752A1
公开(公告)日:2011-09-08
申请号:US13026331
申请日:2011-02-14
申请人: Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, JR. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
发明人: Jerald K. Rasmussen , Kannan Seshadri , Robert T. Fitzsimons, JR. , James I. Hembre , Catherine A. Bothof , Erin A. Satterwhite , George W. Griesgraber , Yi He , Louis C. Haddad
CPC分类号: C07K1/14 , B01D21/01 , C08F120/60 , C08F126/02 , C08G69/10 , C08G73/0206 , C08G73/022 , C08G73/028 , C08L77/04 , C08L79/02 , C08L83/08 , C12N7/02 , C12N11/08 , G01N33/54393 , G01N33/545 , Y10T428/249978 , Y10T428/249991 , Y10T428/2935 , Y10T428/2998 , Y10T442/20
摘要: Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
摘要翻译: 配体功能化底物,制备配体官能化底物的方法,以及使用官能化底物的方法。
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