公开(公告)号：US20050279614A1

公开(公告)日：2005-12-22

申请号：US11212085

申请日：2005-08-25

申请人： Edward Dickinson ,  Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Bruce LeDoyt

发明人： Edward Dickinson ,  Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Bruce LeDoyt

IPC分类号： B65G15/14 ,  B65G29/02 ,  B65G47/252 ,  B65G37/00

CPC分类号： B65G29/02 ,  B65G15/14 ,  B65G47/252

摘要： A flipping apparatus for turning over product pieces such as potato crisps having a first conveyor and a second conveyor. A terminal portion of the first conveyor is nested within a concavity defined by an upturned and curved portion of the second conveyor. A channel is provided between the first conveyor and the curved portion of the second conveyor through which the product pieces can pass. Centrifugal force along the curved portion promotes a gentle and effective transfer of the product pieces from the first conveyor to the second conveyor. Thereby, the product pieces are turned over.

公开(公告)号：US20050077150A1

公开(公告)日：2005-04-14

申请号：US10684937

申请日：2003-10-14

申请人： Edward Dickinson ,  Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Bruce LeDoyt

发明人： Edward Dickinson ,  Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Bruce LeDoyt

IPC分类号： B65G15/14 ,  B65G29/02 ,  B65G47/252 ,  B65G47/248

CPC分类号： B65G29/02 ,  B65G15/14 ,  B65G47/252

摘要： A flipping apparatus for turning over product pieces such as potato crisps having a first conveyor and a second conveyor. A terminal portion of the first conveyor is nested within a concavity defined by an upturned and curved portion of the second conveyor. A channel is provided between the first conveyor and the curved portion of the second conveyor through which the product pieces can pass. Centrifugal force along the curved portion promotes a gentle and effective transfer of the product pieces from the first conveyor to the second conveyor. Thereby, the product pieces are turned over.

摘要翻译： 一种用于翻转诸如具有第一输送机和第二输送机的马铃薯薯片的产品的翻转装置。 第一输送机的端部嵌套在由第二输送机的向上弯曲部分限定的凹部内。 在第一输送机和第二输送机的弯曲部分之间设置通道，产品可以穿过该通道。 沿着弯曲部分的离心力促进产品从第一输送机到第二输送机的平缓和有效的转移。 由此，产品被翻转。

公开(公告)号：US20050016447A1

公开(公告)日：2005-01-27

申请号：US10889823

申请日：2004-07-13

申请人： Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Ali Peyrovi ,  Donald Tatsch ,  Mehrnaz Vafaie ,  Tim Wilding

发明人： Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Ali Peyrovi ,  Donald Tatsch ,  Mehrnaz Vafaie ,  Tim Wilding

IPC分类号： A23G3/20 ,  A23L27/00 ,  A47J37/12 ,  B05C19/04 ,  B05C19/06 ,  B65G15/10 ,  B65G47/66

CPC分类号： B65G15/105 ,  A21C15/002 ,  A23L7/117 ,  A23L7/13 ,  A23P20/12 ,  B65G47/66 ,  B65G2201/0202

摘要： Seasoning for use with snack chips can be recovered and recycled. A seasoning permeable conveyor transports snack chips through a seasoning application. The seasoning applicator deposits seasoning onto the snack chips. The conveyor allows the seasoning not adhered to the moving snack chips to substantially pass through and by toward a seasoning recoverer. The seasoning recoverer, which is positioned beneath the conveyor, collects the seasoning for purification and blending with fresh seasoning. After blending, the seasoning mixture is transported to the seasoning application for use.

公开(公告)号：US20060016390A1

公开(公告)日：2006-01-26

申请号：US11225229

申请日：2005-09-13

申请人： Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Ali Peyrovi ,  Donald Tatsch ,  Mehrnaz Vafaie ,  Tim Wilding

发明人： Kathryn Dove ,  Joseph Gold ,  Ponnattu Joseph ,  Ali Peyrovi ,  Donald Tatsch ,  Mehrnaz Vafaie ,  Tim Wilding

IPC分类号： A21C9/04

CPC分类号： B65G15/105 ,  A21C15/002 ,  A23L7/117 ,  A23L7/13 ,  A23P20/12 ,  B65G47/66 ,  B65G2201/0202

摘要： Seasoning for use with snack chips can be recovered and recycled. A seasoning permeable conveyor transports snack chips through a seasoning application. The seasoning applicator deposits seasoning onto the snack chips. The conveyor allows the seasoning not adhered to the moving snack chips to substantially pass through and by toward a seasoning recoverer. The seasoning recoverer, which is positioned beneath the conveyor, collects the seasoning for purification and blending with fresh seasoning. After blending, the seasoning mixture is transported to the seasoning application for use.

摘要翻译： 可以回收和回收用于小吃切片的调味料。 经调味的输送机通过调味料运送小吃片。 调料机将调味料调料到小吃片上。 输送机允许调味料不会附着在移动的小吃片上，从而基本上经过调味料回收器。 位于输送机下面的调味料回收机收集调味料以进行新鲜调味料的纯化和混合。 混合后，将调味混合物运送到调味品应用中使用。

公开(公告)号：US4867978A

公开(公告)日：1989-09-19

申请号：US276059

申请日：1988-11-25

申请人： Joseph Gold

发明人： Joseph Gold

IPC分类号： A61K33/02 ,  A61K33/04

CPC分类号： A61K33/04 ,  A61K33/02

摘要： Hydrazine sulfate, alone or formulated with liquid or solid carriers, will prolong patient survival when administered to early-stage human cancer patients parenterally or orally.

摘要翻译： 单独使用或与液体或固体载体一起配制的硫酸肼将在肠胃外或口服给予早期人类癌症患者时延长患者的存活时间。

公开(公告)号：US20050054092A1

公开(公告)日：2005-03-10

申请号：US10805099

申请日：2004-03-19

申请人： Chunhui Xu ,  Joseph Gold

发明人： Chunhui Xu ,  Joseph Gold

IPC分类号： A61K35/12 ,  C12N5/0735 ,  C12N5/077 ,  C12N5/08

CPC分类号： C12N5/0606 ,  A61K35/12 ,  C12N5/0657 ,  C12N2500/30 ,  C12N2500/44 ,  C12N2500/62 ,  C12N2501/06 ,  C12N2501/105 ,  C12N2501/15 ,  C12N2501/155 ,  C12N2501/16 ,  C12N2501/385 ,  C12N2501/999 ,  C12N2503/02 ,  C12N2506/02 ,  C12N2510/00

摘要： This invention provides populations human cells of the cardiomyocyte lineage. The cells are obtained by causing cultures of pluripotent stem cells to differentiate in vitro, and then harvesting cells with certain phenotypic features. Differentiated cells bear cell surface and morphologic markers characteristic of cardiomyocytes, and a proportion of them undergo spontaneous periodic contraction. Highly enriched populations of cardiomyocytes and their replicating precursors can be obtained, suitable for use in a variety of applications, such as drug screening and therapy for cardiac disease.

摘要翻译： 本发明提供了心肌细胞谱系的群体人细胞。 通过使多能干细胞的培养物在体外分化获得细胞，然后收获具有某些表型特征的细胞。 分化细胞具有心肌细胞特征的细胞表面和形态学标记，其中一部分经历自发性周期性收缩。 可以获得高度富集的心肌细胞群及其复制前体，适用于各种应用，如药物筛选和心脏病治疗。

公开(公告)号：US4110437A

公开(公告)日：1978-08-29

申请号：US765362

申请日：1977-02-03

申请人： Joseph Gold

发明人： Joseph Gold

IPC分类号： A61K33/04 ,  A61K33/02

CPC分类号： A61K33/04

摘要： Hydrazine sulfate alone or formulated with liquid or solid carriers will retard and reduce cancerous cachexia even in the absence of tumor reduction when administered to humans either orally or parenterally.

公开(公告)号：USD929862S1

公开(公告)日：2021-09-07

申请号：US29672055

申请日：2018-12-03

申请人： GALILEE WINECELLAR JOSEPH GOLD & SONS LTD.

设计人： Joseph Gold

公开(公告)号：US20050153445A1

公开(公告)日：2005-07-14

申请号：US11010140

申请日：2004-12-10

申请人： Ramkumar Mandalam ,  Chunhui Xu ,  Joseph Gold ,  Melissa Carpenter

发明人： Ramkumar Mandalam ,  Chunhui Xu ,  Joseph Gold ,  Melissa Carpenter

IPC分类号： C12N15/09 ,  A61K35/12 ,  A61P43/00 ,  C12N5/0735 ,  C12N5/077 ,  C12N5/079 ,  C12N5/0793 ,  C12N5/10 ,  C12N15/10 ,  C12N5/08

CPC分类号： C12N15/1096 ,  C12N5/0062 ,  C12N5/0068 ,  C12N5/0075 ,  C12N5/0603 ,  C12N5/0606 ,  C12N5/0607 ,  C12N5/0619 ,  C12N5/0622 ,  C12N5/0662 ,  C12N5/0671 ,  C12N5/0672 ,  C12N5/0678 ,  C12N5/068 ,  C12N5/0692 ,  C12N5/0693 ,  C12N5/0696 ,  C12N11/04 ,  C12N15/1034 ,  C12N2500/25 ,  C12N2500/90 ,  C12N2500/98 ,  C12N2500/99 ,  C12N2501/065 ,  C12N2501/105 ,  C12N2501/115 ,  C12N2501/119 ,  C12N2501/125 ,  C12N2501/13 ,  C12N2501/145 ,  C12N2501/155 ,  C12N2501/2306 ,  C12N2501/235 ,  C12N2501/237 ,  C12N2501/26 ,  C12N2501/998 ,  C12N2502/13 ,  C12N2502/99 ,  C12N2503/02 ,  C12N2506/02 ,  C12N2510/00 ,  C12N2510/04 ,  C12N2533/50 ,  C12N2533/90

摘要： This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy.

摘要翻译： 本公开提供了一种用于培养人多能干细胞的改进系统。 传统上，多能干细胞在一层饲养细胞（如小鼠胚胎成纤维细胞）上培养以防止它们分化。 在这里描述的系统中，饲养细胞的作用由添加到培养环境中的组分代替，其支持快速增殖而不分化。 有效的特征是细胞的合适的支持结构，以及可以在不被另一种细胞类型预处理的情况下可以新鲜添加到培养物中的有效培养基。 在根据本发明的新鲜培养基中培养人胚胎干细胞导致细胞惊人地快速扩张，同时保持分化成代表所有三个胚胎胚层的细胞的能力。 这种新的培养系统允许pPS细胞的大量增殖用于商业生产用于药物筛选和人类治疗的重要产品。

公开(公告)号：US20050153444A1

公开(公告)日：2005-07-14

申请号：US11009571

申请日：2004-12-10

申请人： Ramkumar Mandalam ,  Chunhui Xu ,  Joseph Gold ,  Melissa Carpenter

发明人： Ramkumar Mandalam ,  Chunhui Xu ,  Joseph Gold ,  Melissa Carpenter

IPC分类号： C12N15/09 ,  A61K35/12 ,  A61P43/00 ,  C12N5/0735 ,  C12N5/077 ,  C12N5/079 ,  C12N5/0793 ,  C12N5/10 ,  C12N15/10 ,  C12N5/08

CPC分类号： C12N15/1096 ,  C12N5/0062 ,  C12N5/0068 ,  C12N5/0075 ,  C12N5/0603 ,  C12N5/0606 ,  C12N5/0607 ,  C12N5/0619 ,  C12N5/0622 ,  C12N5/0662 ,  C12N5/0671 ,  C12N5/0672 ,  C12N5/0678 ,  C12N5/068 ,  C12N5/0692 ,  C12N5/0693 ,  C12N5/0696 ,  C12N11/04 ,  C12N15/1034 ,  C12N2500/25 ,  C12N2500/90 ,  C12N2500/98 ,  C12N2500/99 ,  C12N2501/065 ,  C12N2501/105 ,  C12N2501/115 ,  C12N2501/119 ,  C12N2501/125 ,  C12N2501/13 ,  C12N2501/145 ,  C12N2501/155 ,  C12N2501/2306 ,  C12N2501/235 ,  C12N2501/237 ,  C12N2501/26 ,  C12N2501/998 ,  C12N2502/13 ,  C12N2502/99 ,  C12N2503/02 ,  C12N2506/02 ,  C12N2510/00 ,  C12N2510/04 ,  C12N2533/50 ,  C12N2533/90

摘要： This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is replaced by components added to the culture environment that support rapid proliferation without differentiation. Effective features are a suitable support structure for the cells, and an effective medium that can be added fresh to the culture without being preconditioned by another cell type. Culturing human embryonic stem cells in fresh medium according to this invention causes the cells to expand surprisingly rapidly, while retaining the ability to differentiate into cells representing all three embryonic germ layers. This new culture system allows for bulk proliferation of pPS cells for commercial production of important products for use in drug screening and human therapy.

摘要翻译： 本公开提供了一种用于培养人多能干细胞的改进系统。 传统上，多能干细胞在一层饲养细胞（如小鼠胚胎成纤维细胞）上培养以防止它们分化。 在这里描述的系统中，饲养细胞的作用由添加到培养环境中的组分代替，其支持快速增殖而不分化。 有效的特征是细胞的合适的支持结构，以及可以在不被另一种细胞类型预处理的情况下可以新鲜添加到培养物中的有效培养基。 在根据本发明的新鲜培养基中培养人胚胎干细胞导致细胞惊人地快速扩张，同时保持分化成代表所有三个胚胎胚层的细胞的能力。 这种新的培养系统允许pPS细胞的大量增殖用于商业生产用于药物筛选和人类治疗的重要产品。