Method and apparatus for identifying mechanisms responsible for “no-trouble-found” (NTF) events in computer systems
    8.
    发明授权
    Method and apparatus for identifying mechanisms responsible for “no-trouble-found” (NTF) events in computer systems 有权
    用于识别负责计算机系统中“无故障发现”(NTF)事件的机制的方法和装置

    公开(公告)号:US07171586B1

    公开(公告)日:2007-01-30

    申请号:US10739827

    申请日:2003-12-17

    IPC分类号: G06F11/00

    摘要: One embodiment of the present invention provides a technique for detecting anomalies during operation of a test computer system. Initially, a golden system and the test system are equipped with the same hardware configuration, wherein the golden system has gone through extensive qualification testing and is presumed to be operating correctly. Next, a deterministic load is executed on the golden system, and values for performance parameters from the golden system are monitored while the deterministic load is executing. Similarly, the deterministic load is also executed on the test system, and values for performance parameters from the test system are monitored while the deterministic load is executing. Next, pairwise differences are computed between values for performance parameters received from the test system and values for performance parameters received from the golden system. Finally, change detection techniques are applied to the pairwise differences to detect anomalies during operation of the test system.

    摘要翻译: 本发明的一个实施例提供一种用于在测试计算机系统的操作期间检测异常的技术。 最初,黄金系统和测试系统配备相同的硬​​件配置,其中黄金系统已经经过广泛的资格测试,并被认为是正常运行。 接下来,在黄金系统上执行确定性负载,并且在执行确定性负载时监视来自黄金系统的性能参数的值。 类似地,确定性负载也在测试系统上执行,并且在执行确定性负载时监视来自测试系统的性能参数的值。 接下来,在从测试系统接收的性能参数的值和从黄金系统接收的性能参数的值之间计算成对差异。 最后,将变化检测技术应用于成对差异,以检测测试系统运行过程中的异常情况。

    System and Method for Determining Copies-per-Unit-Volume Using PCR and Flow Control of Droplets
    9.
    发明申请
    System and Method for Determining Copies-per-Unit-Volume Using PCR and Flow Control of Droplets 有权
    使用PCR和流量控制液滴确定每单位体积份数的系统和方法

    公开(公告)号:US20140248623A1

    公开(公告)日:2014-09-04

    申请号:US14009304

    申请日:2012-03-30

    IPC分类号: C12Q1/68

    摘要: Methods and systems for quantification of a target nucleic acid in a sample are provided. The method includes forming a plurality of discrete sample portions. Each of the plurality of discrete sample portions comprising a portion of the sample, and a reaction mixture. The method further includes amplifying the plurality of discrete sample portions to form a plurality of discrete processed sample portions. At least one discrete processed sample portion containing nucleic acid amplification reaction products. Fluorescence signals are detected from the at least one of the plurality of discrete processed sample portions to determine a presence of the at least one target nucleic acid. The method also includes determining the respective volumes of the plurality of the plurality of discrete processed sample portions, and estimating the number of copies-per-unit-volume of the at least one target nucleic acid in the sample. Estimating the number of copies-per-unit-volume is based on the number of discrete processed sample portions determined to contain the at least one target nucleic acid therein.

    摘要翻译: 提供了用于定量样品中靶核酸的方法和系统。 该方法包括形成多个离散的样本部分。 多个离散样品部分中的每一个包含样品的一部分和反应混合物。 该方法还包括放大多个离散样本部分以形成多个离散处理的样本部分。 至少一个离散加工的样品部分含有核酸扩增反应产物。 从所述多个离散处理样品部分中的至少一个检测荧光信号以确定所述至少一种靶核酸的存在。 该方法还包括确定多个多个离散处理的样本部分的相应体积,以及估计样品中至少一个靶核酸的每单位体积的拷贝数。 估计每单位体积的拷贝数是基于确定为在其中含有至少一种靶核酸的离散加工样品部分的数量。